TY  - JOUR
A1  - Bramborg, Andrea
A1  - Linker, Torsten
T1  - Selective synthesis of 1,4-dialkylbenzenes from terephthalic acid
N2  - Terephthalic acid reacts with alkyl halides under Birch conditions to substituted 1,4-cyclohexadienes in high yields and good stereoselectivities. Electrophiles containing ester or nitrile groups undergo a surprising fragmentation under the reaction conditions. Subsequent treatment with chlorosulfonic acid proceeds by an interesting tandem decarbonylation/decarboxylation, affording 1,4-dialkylbenzenes in excellent regioselectivity. Thus our new method is superior to classical Friedel-Crafts alkylations.
Y1  - 2010
UR  - http://www3.interscience.wiley.com/cgi-bin/jhome/77002176
U6  - https://doi.org/10.1002/adsc.201000322
SN  - 1615-4150
ER  -