TY  - JOUR
A1  - Secker, Christian
A1  - Brosnan, Sarah M.
A1  - Limberg, Felix Rolf Paul
A1  - Braun, Ulrike
A1  - Trunk, Matthias
A1  - Strauch, Peter
A1  - Schlaad, Helmut
T1  - Thermally Induced Crosslinking of Poly(N-Propargyl Glycine)
JF  - Macromolecular chemistry and physics
N2  - As polypeptoids become increasingly popular, they present a more soluble and processable alternative to natural and synthetic polypeptides; the breadth of their potential functionality slowly comes into focus. This report analyzes the ability of an alkyne-functionalized polypeptoid, poly(N-propargyl glycine), to crosslink upon heating. The crosslinking process is analyzed by thermal analysis (differential scanning calorimetry and thermogravimetric analysis), Fourier-transform infrared, electron paramagnetic resonance, and solid-state NMR spectroscopy. While a precise mechanism cannot be confidently assigned, it is clear that the reaction proceeds by a radical mechanism that exclusively involves the alkyne functionality, which, upon crosslinking, yields alkene and aromatic products.
KW  - Fourier-transform infrared
KW  - metal-free crosslinking
KW  - polypeptoid
KW  - propargyl
KW  - solid-state NMR
Y1  - 2015
U6  - https://doi.org/10.1002/macp.201500223
SN  - 1022-1352
SN  - 1521-3935
VL  - 216
IS  - 21
SP  - 2080
EP  - 2085
PB  - Wiley-VCH
CY  - Weinheim
ER  -