TY  - JOUR
A1  - Deyou, Tsegaye
A1  - Marco, Makungu
A1  - Heydenreich, Matthias
A1  - Pan, Fangfang
A1  - Gruhonjic, Amra
A1  - Fitzpatrick, Paul A.
A1  - Koch, Andreas
A1  - Derese, Solomon
A1  - Pelletier, Jerry
A1  - Rissanen, Kari
A1  - Yenesew, Abiy
A1  - Erdelyi, Mate
T1  - Isoflavones and Rotenoids from the Leaves of Millettia oblata ssp teitensis
JF  - Journal of natural products
N2  - A new isoflavone, 8-prenylmilldrone (1), and four new rotenoids, oblarotenoids A-D (2-5), along with nine known compounds (6-14), were isolated from the CH2Cl2/CH3OH (1:1) extract of the leaves of Millettia oblata ssp. teitensis by chromatographic separation. The purified compounds were identified by NMR spectroscopic and mass spectrometric analyses, whereas the absolute configurations of the rotenoids were established on the basis of chiroptical data and in some cases by single-crystal X-ray crystallography. Maximaisoflavone J (11) and oblarotenoid C (4) showed weak activity against the human breast cancer cell line MDA-MB-231 with IC50 values of 33.3 and 93.8 mu M, respectively.
Y1  - 2017
U6  - https://doi.org/10.1021/acs.jnatprod.7b00255
SN  - 0163-3864
SN  - 1520-6025
VL  - 80
SP  - 2060
EP  - 2066
PB  - American Chemical Society
CY  - Washington
ER  -