TY  - JOUR
A1  - Czarnecki, Maciej
A1  - Wessig, Pablo
T1  - Scaling Up UV-Mediated Intramolecular Photodehydro-Diels-Alder Reactions Using a Homemade High-Performance Annular Continuous-Flow Reactor
JF  - Organic Process Research & Development
N2  - Here we present a self-made annular continuous-flow reactor that can be used in the UV/vis range in an internal numbering-up manner. As a model reaction, we chose a powerful batch-scale-limited benzoannelation method, namely, an intramolecular photodehydro-Diels-Alder (IMPDDA) reaction. The scale-up potential of this particular photochemical benchmark reaction toward the preparation of macrocylic (1,7)naphthalenophanes by variation of selected flow parameters is presented.
KW  - flow photochemistry
KW  - photocycloaddition
KW  - photodehydro-Diels-Alder reaction
KW  - scale-up
Y1  - 2018
U6  - https://doi.org/10.1021/acs.oprd.8b00353
SN  - 1083-6160
SN  - 1520-586X
VL  - 22
IS  - 12
SP  - 1823
EP  - 1827
PB  - American Chemical Society
CY  - Washington
ER  -