TY - BOOK ED - Schmidt, Marco F. T1 - Drug target miRNA BT - methods and protocols T3 - Methods in Molecular Biology N2 - This volume provides a concise and technical discussion of recently developed approaches to overcome challenges in miRNA drug discovery. Drug Target miRNA: Methods and Protocols explores strategies to overcome pharmacodynamics and pharmacokinetics challenges. These strategies cover anti-sense agents targeting miRNA that are applied in advanced formulations or are chemically optimized to increase delivery; small molecule miRNA modulators to overcome anti-sense agents’ limitations; general enhancers of miRNA maturation; and Argonaute 2 protein and its pharmacokinetic parameters. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Drug Target miRNA: Methods and Protocols is a valuable resource for anyone interested in the ever-evolving field of miRNA drug discovery. Y1 - 2017 SN - 978-1-4939-6561-8 SN - 978-1-4939-6563-2 U6 - https://doi.org/10.1007/978-1-4939-6563-2 SN - 1064-3745 SN - 1940-6029 PB - Springer CY - New York ER - TY - JOUR ED - Scheller, Frieder W. T1 - Biosensors Y1 - 2002 UR - http://www.elsevier.com/locate/issn/13890352 ER - TY - JOUR ED - Kleine-Vehn, Jürgen ED - Sauer, Michael T1 - Plant Hormones BT - Methods and Protocols JF - Methods in Molecular Biology N2 - This volume aims to present a representative cross-section of modern experimental approaches relevant to Plant Hormone Biology, ranging from relatively simple physiological to highly sophisticated methods. Chapters describe physiological, developmental, microscopy-based techniques, measure hormone contents, and heterologous systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. KW - phenotyping KW - four-dimensional tissue reconstruction KW - hormonal pathways KW - measure hormone contents KW - heterologous systems Y1 - 2017 SN - 978-1-4939-6467-3 SN - 978-1-4939-8210-3 SN - 978-1-4939-6469-7 U6 - https://doi.org/10.1007/978-1-4939-6469-7 SN - 1064-3745 SN - 1940-6029 IS - 1497 PB - Springer CY - New York ER - TY - JOUR ED - Gronau, Norbert ED - Eggert, Sandy T1 - Auswahl, Einführung und Integration von ERP-Systemen Y1 - 2006 SN - 3-936771-91-6 PB - GITO CY - Berlin ER - TY - BOOK ED - Rogge, Detlev T1 - Helgoland-Praktikum : Ergebnisse des zoologisch-meeresbiologischen Praktikums mit Studierenden der Universität Potsdam an der Biologischen Anstalt Helgoland Y1 - 1994 PB - Univ. CY - Potsdam ER - TY - BOOK ED - Holtzhauer, Martin T1 - Methoden in der Proteinanalytik Y1 - 1996 PB - Springer CY - Berlin ER - TY - BOOK ED - Walz, Bernd ED - Somlyo, Avril D. T1 - Calcium and vision : collected papers and reviews Y1 - 1995 ER - TY - BOOK ED - Rösing, Friedrich Wilhelm ED - Greil, Holle ED - Henneberg, Maciej ED - Schultz, Michael T1 - Homo : journal of comparative human biology Y1 - 1998 SN - 0018-442X PB - Urban & Fischer CY - Jena ER - TY - BOOK ED - Scheller, Frieder W. T1 - Frontiers in biosensorics : 2. Practical applications Y1 - 1997 SN - 3-7643-5479-8 VL - 81 PB - Birkhäuser CY - Basel, Boston, Berlin ER - TY - BOOK ED - Scheller, Frieder W. T1 - Frontiers in biosensorics : 1. Fundamental aspects Y1 - 1997 SN - 3-7643-5475-5 VL - 80 PB - Birkhäuser CY - Basel, Boston, Berlin ER -