TY  - GEN
A1  - Wutke, Saskia
A1  - Andersson, Leif
A1  - Benecke, Norbert
A1  - Sandoval-Castellanos, Edson
A1  - Gonzalez, Javier
A1  - Hallsson, Jon Hallsteinn
A1  - Lougas, Lembi
A1  - Magnell, Ola
A1  - Morales-Muniz, Arturo
A1  - Orlando, Ludovic
A1  - Palsdottir, Albina Hulda
A1  - Reissmann, Monika
A1  - Munoz-Rodriguez, Mariana B.
A1  - Ruttkay, Matej
A1  - Trinks, Alexandra
A1  - Hofreiter, Michael
A1  - Ludwig, Arne
T1  - The origin of ambling horses
T2  - Current biology
N2  - Horseback riding is the most fundamental use of domestic horses and has had a huge influence on the development of human societies for millennia. Over time, riding techniques and the style of riding improved. Therefore, horses with the ability to perform comfortable gaits (e.g. ambling or pacing), so-called ‘gaited’ horses, have been highly valued by humans, especially for long distance travel. Recently, the causative mutation for gaitedness in horses has been linked to a substitution causing a premature stop codon in the DMRT3 gene (DMRT3_Ser301STOP) [1]. In mice, Dmrt3 is expressed in spinal cord interneurons and plays an important role in the development of limb movement coordination [1]. Genotyping the position in 4396 modern horses from 141 breeds revealed that nowadays the mutated allele is distributed worldwide with an especially high frequency in gaited horses and breeds used for harness racing [2]. Here, we examine historic horse remains for the DMRT3 SNP, tracking the origin of gaitedness to Medieval England between 850 and 900 AD. The presence of the corresponding allele in Icelandic horses (9th–11th century) strongly suggests that ambling horses were brought from the British Isles to Iceland by Norse people. Considering the high frequency of the ambling allele in early Icelandic horses, we believe that Norse settlers selected for this comfortable mode of horse riding soon after arrival. The absence of the allele in samples from continental Europe (including Scandinavia) at this time implies that ambling horses may have spread from Iceland and maybe also the British Isles across the continent at a later date.
Y1  - 2016
U6  - https://doi.org/10.1016/j.cub.2016.07.001
SN  - 0960-9822
SN  - 1879-0445
VL  - 26
SP  - R697
EP  - R699
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Schubert, Mikkel
A1  - Jonsson, Hakon
A1  - Chang, Dan
A1  - Sarkissian, Clio Der
A1  - Ermini, Luca
A1  - Ginolhac, Aurelien
A1  - Albrechtsen, Anders
A1  - Dupanloup, Isabelle
A1  - Foucal, Adrien
A1  - Petersen, Bent Larsen
A1  - Fumagalli, Matteo
A1  - Raghavan, Maanasa
A1  - Seguin-Orlando, Andaine
A1  - Korneliussen, Thorfinn S.
A1  - Velazquez, Amhed M. V.
A1  - Stenderup, Jesper
A1  - Hoover, Cindi A.
A1  - Rubin, Carl-Johan
A1  - Alfarhan, Ahmed H.
A1  - Alquraishi, Saleh A.
A1  - Al-Rasheid, Khaled A. S.
A1  - MacHugh, David E.
A1  - Kalbfleisch, Ted
A1  - MacLeod, James N.
A1  - Rubin, Edward M.
A1  - Sicheritz-Ponten, Thomas
A1  - Andersson, Leif
A1  - Hofreiter, Michael
A1  - Marques-Bonet, Tomas
A1  - Gilbert, M. Thomas P.
A1  - Nielsen, Rasmus
A1  - Excoffier, Laurent
A1  - Willerslev, Eske
A1  - Shapiro, Beth
A1  - Orlando, Ludovic
T1  - Prehistoric genomes reveal the genetic foundation and cost of horse domestication
JF  - Proceedings of the National Academy of Sciences of the United States of America
Y1  - 2014
U6  - https://doi.org/10.1073/pnas.1416991111
SN  - 0027-8424
VL  - 111
IS  - 52
SP  - E5661
EP  - E5669
PB  - National Acad. of Sciences
CY  - Washington
ER  -