TY - JOUR A1 - Czapka, Sophia A1 - Schwieter, John W. A1 - Festman, Julia T1 - The influence of peripheral emotions on inhibitory control among children JF - Acta psychologica : international journal of psychonomics N2 - In this study, we investigated the cognitive-emotional interplay by measuring the effects of executive competition (Pessoa, 2013), i.e., how inhibitory control is influenced when emotional information is encountered. Sixty-three children (8 to 9 years of age) participated in an inhibition task (central task) accompanied by happy, sad, or neutral emoticons (displayed in the periphery). Typical interference effects were found in the main task for speed and accuracy, but in general, these effects were not additionally modulated by the peripheral emoticons indicating that processing of the main task exhausted the limited capacity such that interference from the task-irrelevant, peripheral information did not show (Pessoa, 2013). Further analyses revealed that the magnitude of interference effects depended on the order of congruency conditions: when incongruent conditions preceded congruent ones, there was greater interference. This effect was smaller in sad conditions, and particularly so at the beginning of the experiment. These findings suggest that the bottom-up perception of task-irrelevant emotional information influenced the top-down process of inhibitory control among children in the sad condition when processing demands were particularly high. We discuss if the salience and valence of the emotional stimuli as well as task demands are the decisive characteristics that modulate the strength of this relation. KW - Executive function KW - Inhibitory control task KW - Cognitive emotional KW - regulation KW - Primary school children Y1 - 2022 U6 - https://doi.org/10.1016/j.actpsy.2022.103507 SN - 0001-6918 SN - 1873-6297 VL - 223 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Duit, Andreas A1 - Lim, Sijeong A1 - Sommerer, Thomas T1 - The state and the environment BT - environmental policy and performance in 37 countries 1970–2010 JF - Politics & policy N2 - The limitations and possibilities of the state in solving societal problems are perennial issues in the political and policy sciences and increasingly so in studies of environmental politics. With the aim of better understanding the role of the state in addressing environmental degradation through policy making, this article investigates the nexus between the environmental policy outputs and the environmental performance. Drawing on three theoretical perspectives on the state and market nexus in the environmental dilemma, we identify five distinct pathways. We then examine the extent to which these pathways are manifested in the real world. Our empirical investigation covers up to 37 countries for the period 1970–2010. While we see no global pattern of linkages between policy outputs and performance, our exploratory analysis finds evidence of policy effects, which suggest that the state can, under certain circumstances, improve the environment through policy making. KW - comparative environmental politics KW - ecological modernization KW - environmental degradation KW - environmental policy effects KW - environmental policy performance KW - national ecological footprint KW - policy output KW - regulation KW - state KW - treadmill of production KW - política ambiental comparada KW - modernización ecológica KW - huella ecológica KW - regulación estatal Y1 - 2023 U6 - https://doi.org/10.1111/polp.12561 SN - 1555-5623 SN - 1747-1346 VL - 51 IS - 6 SP - 1046 EP - 1068 PB - Wiley-Blackwell CY - Hoboken, NJ ER - TY - JOUR A1 - Ebers, Martin A1 - Hoch, Veronica R. S. A1 - Rosenkranz, Frank A1 - Ruschemeier, Hannah A1 - Steinrötter, Björn T1 - The European Commission’s proposal for an Artificial Intelligence Act BT - a critical assessment by members of the Robotics and AI Law Society (RAILS) JF - J : multidisciplinary scientific journal N2 - On 21 April 2021, the European Commission presented its long-awaited proposal for a Regulation “laying down harmonized rules on Artificial Intelligence”, the so-called “Artificial Intelligence Act” (AIA). This article takes a critical look at the proposed regulation. After an introduction (1), the paper analyzes the unclear preemptive effect of the AIA and EU competences (2), the scope of application (3), the prohibited uses of Artificial Intelligence (AI) (4), the provisions on high-risk AI systems (5), the obligations of providers and users (6), the requirements for AI systems with limited risks (7), the enforcement system (8), the relationship of the AIA with the existing legal framework (9), and the regulatory gaps (10). The last section draws some final conclusions (11). KW - artificial intelligence KW - machine learning KW - European Union KW - regulation KW - harmonization KW - Artificial Intelligence Act Y1 - 2021 U6 - https://doi.org/10.3390/j4040043 SN - 2571-8800 VL - 4 IS - 4 SP - 589 EP - 603 PB - MDPI CY - Basel ER - TY - JOUR A1 - Tiberius, Victor A1 - Hauptmeijer, Raoul T1 - Equity crowdfunding BT - Forecasting market development, platform evolution, and regulation JF - Journal of small business management : advancing small business management and entrepreneurship research worldwide / published on behalf of the International Council for Small Business N2 - In this study, we explore the development of equity crowdfunding (ECF) over the next 5 to 10 years by conducting an international Delphi study. Our results indicate that the ECF market is expected to grow significantly. However, it is unlikely to disrupt other forms of financing and will not cover all SME financing needs. ECF will remain a funding technique for SMEs and small investors; it is unlikely to attract large corporations or institutional investors. Platforms will impose stricter requirements for capital raisers, expand their services, and innovate their business models. National governments will probably partly liberalize the ECF market. KW - Equity crowdfunding KW - entrepreneurial finance KW - regulation KW - small KW - business KW - startup funding Y1 - 2021 U6 - https://doi.org/10.1080/00472778.2020.1849714 SN - 0047-2778 SN - 1540-627X VL - 59 IS - 2 SP - 337 EP - 369 PB - Taylor & Francis Group CY - London ER - TY - JOUR A1 - Niere, Oliver A1 - Spannemann, Lisa A1 - Stenzel, Patrick A1 - Bogin, Barry A1 - Hermanussen, Michael A1 - Scheffler, Christiane T1 - Plasticity of human growth BT - a systematic review on psychosocial factors influencing growth JF - Journal of biological and clinical anthropology : Anthropologischer Anzeiger ; Mitteilungsorgan der Gesellschaft für Anthropologie N2 - Background: This systematic review aimed at collecting, analyzing and summarizing scientific studies focusing on psychosocial factors that influence linear growth among humans. Methods: The online database "PubMed" was used in order to acquire suitable scientific studies. These studies were evaluated based on clearly defined criteria that determine whether a study was to be excluded or included in the literature review. In the end, a total sum of 36 studies remained, which were carefully analyzed and used to generate an overview of the association between psychosocial factors and linear growth. Results: In the 36 reviewed studies, different social and psychological factors, such as socioeconomic status, parental education or emotional deprivation were set in relation to physical growth among humans. The studies were listed and summarized, depending on the investigated psychosocial factor. A clear association between psychosocial factors and growth could be observed in most of the reviewed studies. Discussion: Based on the results of the reviewed studies it could be concluded that the regulation of linear growth is also subject to different psychosocial factors. The way in which the developing human and the specific social environment interact seemed to have a major impact on linear growth. Statusspecific stress was discussed as one possible explanation for the regulating mechanism of human linear growth. KW - linear growth KW - final body height KW - regulation KW - psychosocial factors KW - social factors KW - psychological factors Y1 - 2020 U6 - https://doi.org/10.1127/anthranz/2020/1223 SN - 0003-5548 SN - 2363-7099 VL - 77 IS - 5 SP - 431 EP - 443 PB - Schweizerbart CY - Stuttgart ER - TY - JOUR A1 - Schwahn, Kevin A1 - Nikoloski, Zoran T1 - Data reduction approaches for dissecting transcriptional effects on metabolism JF - Frontiers in plant science N2 - The availability of high-throughput data from transcriptomics and metabolomics technologies provides the opportunity to characterize the transcriptional effects on metabolism. Here we propose and evaluate two computational approaches rooted in data reduction techniques to identify and categorize transcriptional effects on metabolism by combining data on gene expression and metabolite levels. The approaches determine the partial correlation between two metabolite data profiles upon control of given principal components extracted from transcriptomics data profiles. Therefore, they allow us to investigate both data types with all features simultaneously without doing preselection of genes. The proposed approaches allow us to categorize the relation between pairs of metabolites as being under transcriptional or post-transcriptional regulation. The resulting classification is compared to existing literature and accumulated evidence about regulatory mechanism of reactions and pathways in the cases of Escherichia coil, Saccharomycies cerevisiae, and Arabidopsis thaliana. KW - E. coil KW - S. cerevisiae KW - A. thaliana KW - partial correlation KW - principal component analysis KW - metabolomics KW - data reduction KW - regulation Y1 - 2018 U6 - https://doi.org/10.3389/fpls.2018.00538 SN - 1664-462X VL - 9 PB - Frontiers Research Foundation CY - Lausanne ER - TY - GEN A1 - Jekauc, Darko A1 - Brand, Ralf T1 - Editorial: How do Emotions and Feelings Regulate Physical Activity? T2 - Frontiers in psychology KW - physical activity KW - exercise KW - emotions KW - feelings KW - affect KW - regulation KW - implicit KW - enjoyment Y1 - 2017 U6 - https://doi.org/10.3389/fpsyg.2017.01145 SN - 1664-1078 VL - 8 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Hernandez, Martin A. A1 - Gleixner, Gerd A1 - Sachse, Dirk A1 - Alvarez, Hector M. T1 - Carbon Allocation in Rhodococcus jostii RHA1 in Response to Disruption and Overexpression of nlpR Regulatory Gene, Based on C-13-labeling Analysis JF - Frontiers in microbiology N2 - Nitrogen lipid regulator (NlpR) is a pleiotropic regulator that positively controls genes associated with both nitrogen and lipid metabolism in the oleaginous bacterium Rhodococcus jostii RHA1. In this study, we investigated the effect of nlpR disruption and overexpression on the assimilation of C-13-labeled glucose as carbon source, during cultivation of cells under nitrogen-limiting and nitrogen-rich conditions, respectively. Label incorporation into the total lipid extract (TLE) fraction was about 30% lower in the mutant strain in comparison with the wild type strain under low-nitrogen conditions. Moreover, a higher C-13 abundance (similar to 60%) into the extracellular polymeric substance fraction was observed in the mutant strain, nlpR disruption also promoted a decrease in the label incorporation into several TLE-derivative fractions including neutral lipids (NL), glycolipids (GL), phospholipids (PL), triacylglycerols (TAG), diacylglycerols (DAG), and free fatty acids (FFA), with the DAG being the most affected. In contrast, the nlpR overexpression in RHA1 cells under nitrogen-rich conditions produced an increase of the label incorporation into the TLE and its derivative NL and PL fractions, the last one being the highest C-13 enriched. In addition, a higher C-13 enrichment occurred in the TAG, DAG, and FFA fractions after nlpR induction, with the FFA fraction being the most affected within the TLE. Isotopic-labeling experiments demonstrated that NlpR regulator is contributing in oleaginous phenotype of R. jostii RHA1 to the allocation of carbon into the different lipid fractions in response to nitrogen levels, increasing the rate of carbon flux into lipid metabolism. KW - Rhodococcus KW - RHA1 KW - NlpR KW - regulation KW - C-13-glucose KW - lipid metabolism Y1 - 2017 U6 - https://doi.org/10.3389/fmicb.2017.01992 SN - 1664-302X VL - 8 PB - Frontiers Research Foundation CY - Lausanne ER - TY - GEN A1 - Nikoloski, Zoran A1 - van Dongen, Joost T. T1 - Modeling alternatives for interpreting the change in oxygen-consumption rates during hypoxic conditions T2 - New phytologist : international journal of plant science KW - hypoxia KW - modeling KW - regulation KW - respiration KW - roots Y1 - 2011 U6 - https://doi.org/10.1111/j.1469-8137.2011.03674.x SN - 0028-646X VL - 190 IS - 2 SP - 273 EP - 276 PB - Wiley-Blackwell CY - Malden ER - TY - JOUR A1 - Christian, Jan-Ole A1 - Braginets, Rostyslav A1 - Schulze, Waltraud X. A1 - Walther, Dirk T1 - Characterization and prediction of protein phosphorylation hotspots in Arabidopsis thaliana JF - Frontiers in plant science N2 - The regulation of protein function by modulating the surface charge status via sequence-locally enriched phosphorylation sites (P-sites) in so called phosphorylation "hotspots" has gained increased attention in recent years. We set out to identify P-hotspots in the model plant Arabidopsis thaliana. We analyzed the spacing of experimentally detected P-sites within peptide-covered regions along Arabidopsis protein sequences as available from the PhosPhAt database. Confirming earlier reports (Schweiger and Lanial, 2010), we found that, indeed, P-sites tend to cluster and that distributions between serine and threonine P-sites to their respected closest next P-site differ significantly from those for tyrosine P-sites. The ability to predict P-hotspots by applying available computational P-site prediction programs that focus on identifying single P-sites was observed to be severely compromised by the inevitable interference of nearby P-sites. We devised a new approach, named HotSPotter, for the prediction of phosphorylation hotspots. HotSPotter is based primarily on local amino acid compositional preferences rather than sequence position-specific motifs and uses support vector machines as the underlying classification engine. HotSPotter correctly identified experimentally determined phosphorylation hotspots in A. thaliana with high accuracy. Applied to the Arabidopsis proteome, HotSPotter-predicted 13,677 candidate P-hotspots in 9,599 proteins corresponding to 7,847 unique genes. Hotspot containing proteins are involved predominantly in signaling processes confirming the surmised modulating role of hotspots in signaling and interaction events. Our study provides new bioinformatics means to identify phosphorylation hotspots and lays the basis for further investigating novel candidate P-hotspots. All phosphorylation hotspot annotations and predictions have been made available as part of the PhosPhAt database at http://phosphat.mpimp-golm.mpg.de. KW - protein phosphorylation KW - hotspots KW - Arabidopsis thaliana KW - support vector machines KW - regulation Y1 - 2012 U6 - https://doi.org/10.3389/fpls.2012.00207 SN - 1664-462X VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER -