TY - JOUR A1 - Piluso, Susanna A1 - Vukicevie, Radovan A1 - Nöchel, Ulrich A1 - Braune, Steffen A1 - Lendlein, Andreas A1 - Neffe, Axel T. T1 - Sequential alkyne-azide cycloadditions for functionalized gelatin hydrogel formation JF - European polymer journal N2 - While click chemistry reactions for biopolymer network formation are attractive as the defined reactions may allow good control of the network formation and enable subsequent functionalization, tailoring of gelatin network properties over a wide range of mechanical properties has yet to be shown. Here, it is demonstrated that copper-catalyzed alkyne-azide cycloaddition of alkyne functionalized gelatin with diazides gave hydrogel networks with properties tailorable by the ratio of diazide to gelatin and diazide rigidity. 4,4′-diazido-2,2′-stilbenedisulfonic acid, which has been used as rigid crosslinker, yielded hydrogels with Young’s moduli E of 50–390 kPa and swelling degrees Q of 150–250 vol.%, while the more flexible 1,8-diazidooctane resulted in hydrogels with E = 125–280 kPa and Q = 225–470 vol.%. Storage moduli could be varied by two orders of magnitude (G′ = 100–20,000 Pa). An indirect cytotoxicity test did not show cytotoxic properties. Even when employing 1:1 ratios of alkyne and azide moieties, the hydrogels were shown to contain both, unreacted alkyne groups on the gelatin backbone as well as dangling chains carrying azide groups as shown by reaction with functionalized fluorescein. The free groups, which can be tailored by the employed ratio of the reactants, are accessible for covalent attachment of drugs, as was demonstrated by functionalization with dexamethasone. The sequential network formation and functionalization with click chemistry allows access to multifunctional materials relevant for medical applications. KW - Click chemistry KW - Hydrogel KW - Polymer functionalization KW - Biopolymer KW - Rheology KW - Multifunctionality Y1 - 2018 U6 - https://doi.org/10.1016/j.eurpolymj.2018.01.017 SN - 0014-3057 SN - 1873-1945 VL - 100 SP - 77 EP - 85 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Rolf, Werner A1 - Pauleit, Stephan A1 - Wiggering, Hubert T1 - A stakeholder approach, door opener for farmland and multifunctionality in urban green infrastructure JF - Urban forestry & urban greening N2 - During the last years Urban Green Infrastructure (UGI) has evolved as a research focus across Europe. UGI can be understood as a multifunctional network of different urban green spaces and elements contributing to urban benefits. Urban agriculture has gained increasing research interest in this context. While a strong focus has been made on functions and benefits of small scale activities, the question is still open, whether these findings can be up-scaled and transferred to the farmland scale. Furthermore, multifunctionality of urban and peri-urban agriculture is rarely being considered in the landscape context. This research aims to address these gaps and harnesses the question if agricultural landscapes – which in many European metropolitan regions provide significant spatial potential – can contribute to UGI as multifunctional green spaces. This work considers multifunctionality qualitatively based on stakeholder opinion, using a participatory research approach. This study provides new insights in peri-urban farmland potentials for UGI development, resulting into a strategy framework. Furthermore, it reflects on the role of the stakeholder involvement for `multifunctionality planning´. It suggests that it helps to define meaningful bundles of intertwined functions that interact on different scales, helping to deal with non-linearity of multiple functions and to better manage them simultaneously. KW - Benefits KW - Functions KW - Green surge KW - Multifunctionality KW - Participation KW - Peri-urban agriculture KW - Stakeholder KW - Urban learning lab Y1 - 2018 U6 - https://doi.org/10.1016/j.ufug.2018.07.012 SN - 1618-8667 VL - 40 SP - 73 EP - 83 PB - Urban & Fischer CY - Jena ER - TY - JOUR A1 - Wiggering, Hubert A1 - Steinhardt, Uta T1 - A conceptual model for site-specific agricultural land-use JF - Ecological modelling : international journal on ecological modelling and engineering and systems ecolog N2 - Land-use concepts provide decision support for the most efficient usage options according to sustainable development and multifunctionality requirements. However, developments in landscape-related, agricultural production schemes are primarily driven by economic benefits. Therefore, most agricultural land-use concepts tackle particular problems or interests and lack a systemic perspective. As a result, we discuss a conceptual model for future site-specific agricultural land-use with an inbuilt requirement for adequate experimental sites to enable monitoring systems for a new generation of ecosystem models and for new approaches to address science-stakeholder interactions. KW - Site-specific agricultural land-use KW - Concept of differentiated land use KW - Sustainable land use KW - Multifunctionality KW - Modeling tools for decision-making Y1 - 2015 U6 - https://doi.org/10.1016/j.ecolmodel.2014.08.011 SN - 0304-3800 SN - 1872-7026 VL - 295 SP - 42 EP - 46 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Wiggering, Hubert T1 - The geology - land use - nexus JF - Environmental earth sciences KW - Multifunctionality KW - Site-adequate land use KW - Ecosystem services KW - Land use conception Y1 - 2014 U6 - https://doi.org/10.1007/s12665-013-2908-8 SN - 1866-6280 SN - 1866-6299 VL - 71 IS - 12 SP - 5037 EP - 5044 PB - Springer CY - New York ER -