TY - JOUR A1 - Knapp, Michael A1 - Lalueza-Fox, Carles A1 - Hofreiter, Michael T1 - Re-inventing ancient human DNA JF - Investigative Genetics N2 - For a long time, the analysis of ancient human DNA represented one of the most controversial disciplines in an already controversial field of research. Scepticism in this field was only matched by the long-lasting controversy over the authenticity of ancient pathogen DNA. This ambiguous view on ancient human DNA had a dichotomous root. On the one hand, the interest in ancient human DNA is great because such studies touch on the history and evolution of our own species. On the other hand, because these studies are dealing with samples from our own species, results are easily compromised by contamination of the experiments with modern human DNA, which is ubiquitous in the environment. Consequently, some of the most disputed studies published - apart maybe from early reports on million year old dinosaur or amber DNA - reported DNA analyses from human subfossil remains. However, the development of so-called next-or second-generation sequencing (SGS) in 2005 and the technological advances associated with it have generated new confidence in the genetic study of ancient human remains. The ability to sequence shorter DNA fragments than with PCR amplification coupled to traditional Sanger sequencing, along with very high sequencing throughput have both reduced the risk of sequencing modern contamination and provided tools to evaluate the authenticity of DNA sequence data. The field is now rapidly developing, providing unprecedented insights into the evolution of our own species and past human population dynamics as well as the evolution and history of human pathogens and epidemics. Here, we review how recent technological improvements have rapidly transformed ancient human DNA research from a highly controversial subject to a central component of modern anthropological research. We also discuss potential future directions of ancient human DNA research. KW - Archaic humans KW - Human evolution KW - Human population genomics KW - Next/second-generation sequencing Y1 - 2015 U6 - https://doi.org/10.1186/s13323-015-0020-4 SN - 2041-2223 VL - 6 PB - BioMed Central CY - London ER - TY - JOUR A1 - Trauth, Martin H. A1 - Bergner, Andreas G. N. A1 - Foerster, Verena A1 - Junginger, Annett A1 - Maslin, Mark A. A1 - Schäbitz, Frank T1 - Episodes of environmental stability versus instability in Late Cenozoic lake records of Eastern Africa JF - Journal of human evolution N2 - Episodes of environmental stability and instability may be equally important for African hominin speciation, dispersal, and cultural innovation. Three examples of a change from stable to unstable environmental conditions are presented on three different time scales: (1) the Mid Holocene (MH) wet dry transition in the Chew Bahir basin (Southern Ethiopian Rift; between 11 ka and 4 ka), (2) the MIS 5-4 transition in the Naivasha basin (Central Kenya Rift; between 160 ka and 50 ka), and (3) the Early Mid Pleistocene Transition (EMPT) in the Olorgesailie basin (Southern Kenya Rift; between 1.25 Ma and 0.4 Ma). A probabilistic age modeling technique is used to determine the timing of these transitions, taking into account possible abrupt changes in the sedimentation rate including episodes of no deposition (hiatuses). Interestingly, the stable-unstable conditions identified in the three records are always associated with an orbitally-induced decrease of insolation: the descending portion of the 800 kyr cycle during the EMPT, declining eccentricity after the 115 ka maximum at the MIS 5-4 transition, and after similar to 10 ka. This observation contributes to an evidence-based discussion of the possible mechanisms causing the switching between environmental stability and instability in Eastern Africa at three different orbital time scales (10,000 to 1,000,000 years) during the Cenozoic. This in turn may lead to great insights into the environmental changes occurring at the same time as hominin speciation, brain expansion, dispersal out of Africa, and cultural innovations and may provide key evidence to build new hypotheses regarding the causes of early human evolution. (C) 2015 Elsevier Ltd. All rights reserved. KW - Paleoclimate KW - East Africa KW - Human evolution KW - Lakes KW - Sediments Y1 - 2015 U6 - https://doi.org/10.1016/j.jhevol.2015.03.011 SN - 0047-2484 VL - 87 SP - 21 EP - 31 PB - Elsevier CY - London ER - TY - JOUR A1 - Maslin, Mark A. A1 - Brierley, Chris M. A1 - Milner, Alice M. A1 - Shultz, Susanne A1 - Trauth, Martin H. A1 - Wilson, Katy E. T1 - East African climate pulses and early human evolution JF - Quaternary science reviews : the international multidisciplinary research and review journal N2 - Current evidence suggests that all of the major events in hominin evolution have occurred in East Africa. Over the last two decades, there has been intensive work undertaken to understand African palaeoclimate and tectonics in order to put together a coherent picture of how the environment of East Africa has varied in the past. The landscape of East Africa has altered dramatically over the last 10 million years. It has changed from a relatively flat, homogenous region covered with mixed tropical forest, to a varied and heterogeneous environment, with mountains over 4 km high and vegetation ranging from desert to cloud forest. The progressive rifting of East Africa has also generated numerous lake basins, which are highly sensitive to changes in the local precipitation-evaporation regime. There is now evidence that the presence of precession-driven, ephemeral deep-water lakes in East Africa were concurrent with major events in hominin evolution. It seems the unusual geology and climate of East Africa created periods of highly variable local climate, which, it has been suggested could have driven hominin speciation, encephalisation and dispersal out of Africa. One example is the significant hominin speciation and brain expansion event at -1.8 Ma that seems to have been coeval with the occurrence of highly variable, extensive, deep-water lakes. This complex, climatically very variable setting inspired first the variability selection hypothesis, which was then the basis for the pulsed climate variability hypothesis. The newer of the two suggests that the long-term drying trend in East Africa was punctuated by episodes of short, alternating periods of extreme humidity and aridity. Both hypotheses, together with other key theories of climate-evolution linkages, are discussed in this paper. Though useful the actual evolution mechanisms, which led to early hominins are still unclear and continue to be debated. However, it is clear that an understanding of East African lakes and their palaeoclimate history is required to understand the context within which humans evolved and eventually left East Africa. (C) 2014 The Authors. Published by Elsevier Ltd. KW - Human evolution KW - East Africa KW - Palaeoclimatology KW - Palaeoliminology KW - Tectonics KW - Hominin KW - Orbital forcing KW - Cenozoic climate transitions KW - Pulsed climate variability hypothesis Y1 - 2014 U6 - https://doi.org/10.1016/j.quascirev.2014.06.012 SN - 0277-3791 VL - 101 SP - 1 EP - 17 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Maslin, Mark A. A1 - Pancost, Richard D. A1 - Wilson, Katy E. A1 - Lewis, Jonathan A1 - Trauth, Martin H. T1 - Three and half million year history of moisture availability of South West Africa evidence from ODP site 1085 biomarker records JF - Palaeogeography, palaeoclimatology, palaeoecology : an international journal for the geo-sciences N2 - Ocean Drilling Program Site 1085 provides a continuous marine sediment record off southern South West Africa for at least the last three and half million years. The n-alkane partial derivative(13) C record from this site records changes in past vegetation and provides an indication of the moisture availability of SW Africa during this time period. Very little variation, and no apparent trend, is observed in the n-alkane delta C-13 record, suggesting stable long-term conditions despite significant changes in East African tectonics and global climate. Slightly higher n-alkane delta C-13 values occur between 3.5 and 2.7 Ma suggesting slightly drier conditions than today. Between 2.5 and 2.7 Ma there is a shift to more negative n-alkane delta C-13 values suggesting slightly wetter conditions during a similar to 0.2 Ma episode that coincides with the intensification of Northern Hemisphere Glaciation (iNHG). From 2.5 to 0.4 Ma the n-alkane delta C-13 values are very consistent, varying by less than +/- 0.5 parts per thousand and suggesting little or no long-term change in the moisture availability of South West Africa over the last 2.5 million years. This is in contrast to the long-term drying trend observed further north offshore from the Namib Desert and in East Africa. A comparison of the climate history of these regions suggests that Southern Africa may have been an area of long-term stability over the last 3.5 Myrs. KW - Plio-Pleistocene KW - Aridity KW - SW Africa KW - Biomarkers KW - Palaeoclimate KW - Human evolution Y1 - 2012 U6 - https://doi.org/10.1016/j.palaeo.2011.12.009 SN - 0031-0182 VL - 317 SP - 41 EP - 47 PB - Elsevier CY - Amsterdam ER -