TY  - JOUR
A1  - Scheller, Frieder W.
A1  - Lettau, Kristian
T1  - Biomimetische Rezeptoren und Biochips
Y1  - 2003
ER  - 
TY  - JOUR
A1  - Warsinke, Axel
A1  - Lettau, Kristian
A1  - Werner, Deljana
A1  - Micheel, Burkhard
A1  - Kwak, Young-Keun
T1  - Biomimetic Binders and Catalysts for Sensorics = Biomimetische Binder und Katalysatoren für die Sensorik
N2  - Biosensors which make use of the high specificity of enzymes, antibodies, and nucleic acids have been described for detection of numerous metabolites, hormones, and nucleic acid sequences. In addition to biological components nowadays biomimetic recognition molecules are also used. Especially antibodies, aptamers, and molecular imprints are promising biomimetics. They could broaden the range of detectable analytes and could increase the functional stability of the sensor. In this publication we describe the generation of biomimetic antibodies and biomimetic molecular imprints for binding creatinine and for hydrolyzing phenylcarbamates to be used in electrochemical sensors.
Y1  - 2003
UR  - http://www.extenza-eps.com/extenza/loadHTML?objectIDValue=21853&type=abstract
ER  - 
TY  - JOUR
A1  - Lettau, Kristian
A1  - Gajovic-Eichelmann, N.
A1  - Kwak, Young-Keun
A1  - Scheller, Frieder W.
A1  - Warsinke, Axel
T1  - Hydroxylasen und katalytische Polymere für Biochips
Y1  - 2004
ER  - 
TY  - JOUR
A1  - Lettau, Kristian
A1  - Warsinke, Axel
A1  - Laschewsky, André
A1  - Mosbach, K.
A1  - Yilmaz, E.
A1  - Scheller, Frieder W.
T1  - An esterolytic imprinted polymer prepared via a silica-supported transition state analogue
N2  - In this work we describe a new preparation method for an esterolytic imprinted polymer with catalytic sites on the surface. A template was prepared by immobilizing a transition state analogue (phosphoramidic acid derivative) of an esterolytic reaction within porous silica particles. Polymerization within the pores was carried out using 4- vinylimidazole as a functional monomer and divinylbenzene as a cross-linker. The polymer was released by dissolution of the silica support with hydrofluoric acid and catalytic properties were studied by incubation with three different 4- nitrophenylesters and spectrophotometric determination of the released 4-nitrophenol. For 4-nitrophenyl acetate an activity of 211 nmol min(-1) mg(-1) and a K-m value of 2.2 mmol L-1 was obtained
Y1  - 2004
ER  - 
TY  - JOUR
A1  - Lettau, Kristian
A1  - Warsinke, Axel
A1  - Katterle, Martin
A1  - Danielsson, Bengt
A1  - Scheller, Frieder W.
T1  - A bifunctional molecularly imprinted polymer (MIP): analysis of binding and catalysis by a thermistor
N2  - Binding or catalysis? Both can be distinguished with a molecularly imprinted polymer (MIP) by the different patterns of heat generation. The catalytically active sites, like in the corresponding enzyme, generate a steady-state temperature increase. Thus, enzyme-like catalysis and antibody-analogue binding are analyzed simultaneously in a bifunctional MIP for the first time (see scheme).
Y1  - 2006
UR  - http://www3.interscience.wiley.com/cgi-bin/jhome/26737/
U6  - https://doi.org/10.1002/anie.200601796
ER  -