TY - JOUR A1 - Pliatsikas, Christos A1 - Verissimo, Joao Marques A1 - Babcock, Laura A1 - Pullman, Mariel Y. A1 - Glei, Dana A. A1 - Weinstein, Maxine A1 - Goldman, Noreen A1 - Ullman, Michael T. T1 - Working memory in older adults declines with age, but is modulated by sex and education JF - The quarterly journal of experimental psychology N2 - Working memory (WM), which underlies the temporary storage and manipulation of information, is critical for multiple aspects of cognition and everyday life. Nevertheless, research examining WM specifically in older adults remains limited, despite the global rapid increase in human life expectancy. We examined WM in a large sample (N=754) of healthy older adults (aged 58-89) in a non-Western population (Chinese speakers) in Taiwan, on a digit n-back task. We tested not only the influence of age itself and of load (1-back vs. 2-back) but also the effects of both sex and education, which have been shown to modulate WM abilities. Mixed-effects regression revealed that, within older adulthood, age negatively impacted WM abilities (with linear, not nonlinear, effects), as did load (worse performance at 2-back). In contrast, education level was positively associated with WM. Moreover, both age and education interacted with sex. With increasing age, males showed a steeper WM decline than females; with increasing education, females showed greater WM gains than males. Together with other findings, the evidence suggests that age, sex, and education all impact WM in older adults, but interact in particular ways. The results have both basic research and translational implications and are consistent with particular benefits from increased education for women. KW - Ageing KW - sex differences KW - education KW - working memory KW - n back Y1 - 2018 U6 - https://doi.org/10.1177/1747021818791994 SN - 1747-0218 SN - 1747-0226 VL - 72 IS - 6 SP - 1308 EP - 1327 PB - Routledge, Taylor & Francis Group CY - Abingdon ER -