TY  - GEN
A1  - Sowemimo, Oluwakemi
A1  - Borcherds, Wade
A1  - Knox-Brown, Patrick
A1  - Rindfleisch, Tobias
A1  - Thalhammer, Anja
A1  - Daughdrill, Gary
T1  - Evolution of Transient Helicity and Disorder in Late Embryogenesis Abundant Protein COR15A
T2  - Biophysical journal
N2  - Cold regulated protein 15A (COR15A) is a nuclear encoded, intrinsically disordered protein that is found in Arabidopsis thaliana. It belongs to the Late Embryogenesis Abundant (LEA) family of proteins and is responsible for increased freezing tolerance in plants. COR15A is intrinsically disordered in dilute solutions and adopts a helical structure upon dehydration or in the presence of co-solutes such as TFE and ethylene glycol. This helical structure is thought to be important for protecting plants from dehydration induced by freezing. Multiple protein sequence alignments revealed the presence of several conserved glycine residues that we hypothesize keeps COR15A from becoming helical in dilute solutions. Using AGADIR, the change in helical content of COR15A when these conserved glycine residues were mutated to alanine residues was predicted. Based on the predictions, glycine to alanine mutants were made at position 68, and 54,68,81, and 84. Labeled samples of wildtype COR15A and mutant proteins were purified and NMR experiments were performed to examine any structural changes induced by the mutations. To test the effects of dehydration on the structure of COR15A, trifluoroethanol, an alcohol based co solvent that is proposed to induce/stabilize helical structure in peptides was added to the NMR samples, and the results of the experiment showed an increase in helical content, compared to the samples without TFE. To test the functional differences between wild type and the mutants, liposome leakage assays were performed. The results from these assays suggest the more helical mutants may augment membrane stability.
Y1  - 2019
U6  - https://doi.org/10.1016/j.bpj.2018.11.2553
SN  - 0006-3495
SN  - 1542-0086
VL  - 116
IS  - 3
SP  - 473A
EP  - 473A
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Rodriguez-Sillke, Yasmina
A1  - Steinhoff, U.
A1  - Bojarski, Christian
A1  - Lissner, Donata
A1  - Schumann, Michael
A1  - Branchi, F.
A1  - Siegmund, Britta
A1  - Glauben, Rainer
T1  - Deep immune profiling of human Peyer´s Patches in patients of inflammatory bowel diseases
T2  - European journal of immunology
Y1  - 2019
U6  - https://doi.org/10.1002/eji.201970300
SN  - 0014-2980
SN  - 1521-4141
VL  - 49
SP  - 203
EP  - 204
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - GEN
A1  - Radchuk, Viktoriia
A1  - Kramer-Schadt, Stephanie
A1  - Grimm, Volker
T1  - Transferability of mechanistic ecological models is about emergence
T2  - Trends in ecology and evolution
Y1  - 2019
U6  - https://doi.org/10.1016/j.tree.2019.01.010
SN  - 0169-5347
SN  - 1872-8383
VL  - 34
IS  - 6
SP  - 487
EP  - 488
PB  - Elsevier
CY  - London
ER  - 
TY  - GEN
A1  - Numberger, Daniela
A1  - Dreier, Carola
A1  - Vullioud, Colin
A1  - Gabriel, Guelsah
A1  - Greenwood, Alex D.
A1  - Grossart, Hans-Peter
T1  - Correction: Recovery of influenza A viruses from lake water and sediments by experimental inoculation (vol 14, e0216880, 2019)
T2  - PLoS one
Y1  - 2019
U6  - https://doi.org/10.1371/journal.pone.0218882
SN  - 1932-6203
VL  - 14
IS  - 6
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - GEN
A1  - Müller-Schöll, A.
A1  - Klopp-Schulze, Lena
A1  - Huisinga, Wilhelm
A1  - Jörger, M.
A1  - Neven, P.
A1  - Koolen, S. L.
A1  - Mathijssen, R. H. J.
A1  - Schmidt, S.
A1  - Kloft, Charlotte
T1  - Patient-tailored tamoxifen dosing based on an increased quantitative understanding of its complex pharmacokinetics: A novel integrative modelling approach
T2  - Annals of Oncology
Y1  - 2019
SN  - 0923-7534
SN  - 1569-8041
VL  - 30
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - GEN
A1  - Moga, A.
A1  - Robinson, T.
A1  - Leimkühler, Silke
T1  - Towards reconstituting a biosynthetic pathway within compartmentalized GUVs
T2  - European biophysics journal : with biophysics letters ; an international journal of biophysics
Y1  - 2019
SN  - 0175-7571
SN  - 1432-1017
VL  - 48
SP  - S218
EP  - S218
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Luckner, Madlen
A1  - Dunsing, Valentin
A1  - Drüke, Markus
A1  - Zuehlke, B.
A1  - Petazzi, Roberto Arturo
A1  - Chiantia, Salvatore
A1  - Herrmann, A.
T1  - Quantifying protein oligomerization directly in living cells
BT  - a systematic comparison of fluorescent proteins and application to Influenza A virus infection
T2  - European biophysics journal : with biophysics letters ; an international journal of biophysics
Y1  - 2019
SN  - 0175-7571
SN  - 1432-1017
VL  - 48
SP  - S183
EP  - S183
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Höfer, Chris Tina
A1  - Di Lella, Santiago
A1  - Dahmani, Ismail
A1  - Jungnick, Nadine
A1  - Bordag, Natalie
A1  - Bobone, Sara
A1  - Huan, Q.
A1  - Keller, S.
A1  - Herrmann, A.
A1  - Chiantia, Salvatore
T1  - Corrigendum to: Structural determinants of the interaction between influenza A virus matrix protein M1 and lipid membranes (Biochimica et Biophysica Acta (BBA) - Biomembranes. - 1861, (2019), pg 1123-1134)
T2  - Biochimica et biophysica acta : Biomembranes
Y1  - 2019
U6  - https://doi.org/10.1016/j.bbamem.2019.07.002
SN  - 0005-2736
SN  - 1879-2642
VL  - 1861
IS  - 10
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - GEN
A1  - Horreo, J. L.
A1  - Breedveld, Merel Cathelijne
A1  - Lindtke, D.
A1  - Heulin, B.
A1  - Surget-Groba, Yann
A1  - Fitze, Patrick S.
T1  - Correction: Genetic introgression among differentiated clades is lower among clades exhibiting different parity modes. -  (Heredity. - 123, (2019) pg 264)
T2  - Heredity
N2  - The original version of this Article contained an error in the spelling of the author Y. Surget-Groba, which was incorrectly given as J. Surget-Groba. This has now been corrected in both the PDF and HTML versions of the Article.
Y1  - 2019
U6  - https://doi.org/10.1038/s41437-019-0223-1
SN  - 0018-067X
SN  - 1365-2540
VL  - 123
IS  - 2
SP  - 285
EP  - 285
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - GEN
A1  - Hermanussen, Michael
A1  - Scheffler, Christiane
A1  - Groth, Detlef
A1  - Bogin, Barry
T1  - Student work on trends in infant and child growth
BT  - an editorial
T2  - Journal of biological and clinical anthropology : Anthropologischer Anzeiger : Mitteilungsorgan der Gesellschaft für Anthropologie
KW  - nutrition
KW  - impact on growth
KW  - geographic neighborhood
KW  - mortality bias
KW  - limb disproportions
KW  - physical activity
KW  - socioeconomic status
KW  - parental age
KW  - statistical tools
Y1  - 2019
U6  - https://doi.org/10.1127/anthranz/2019/1052
SN  - 0003-5548
VL  - 76
IS  - 5
SP  - 363
EP  - 364
PB  - Schweizerbart
CY  - Stuttgart
ER  -