TY - JOUR A1 - Bäurle, Isabel T1 - Can't remember to forget you BT - Chromatin-based priming of somatic stress responses JF - Seminars in cell & developmental biology N2 - In nature plants are exposed to frequent changes in their abiotic and biotic environment. While some environmental cues are used to gauge the environment and align growth and development, others are beyond the regularly encountered spectrum of a species and trigger stress responses. Such stressful conditions provide a potential threat to survival and integrity. Plants adapt to extreme environmental conditions through physiological adaptations that are usually transient and are maintained until stressful environments subside. It is increasingly appreciated that in some cases environmental cues activate a stress memory that persists for some time after the extreme condition has subsided. Recent research has shown that this stress-induced environmental memory is mediated by epigenetic and chromatin-based mechanisms and both histone methylation and nucleosome occupancy are associated with it. KW - Priming KW - Transcriptional memory KW - Chromatin KW - H3K4 methylation KW - Nucleosome occupancy Y1 - 2017 U6 - https://doi.org/10.1016/j.semcdb.2017.09.032 SN - 1084-9521 VL - 83 SP - 133 EP - 139 PB - Elsevier CY - London ER - TY - JOUR A1 - Czerwon, Beate A1 - Hohlfeld, Annette A1 - Wiese, Heike A1 - Werheid, Katja T1 - Syntactic structural parallelisms influence processing of positive stimuli evidence from cross-modal ERP priming JF - International journal of psychophysiology N2 - Language can strongly influence the emotional state of the recipient. In contrast to the broad body of experimental and neuroscientific research on semantic information and prosodic speech, the emotional impact of grammatical structure has rarely been investigated. One reason for this might be, that measuring effects of syntactic structure involves the use of complex stimuli, for which the emotional impact of grammar is difficult to isolate. In the present experiment we examined the emotional impact of structural parallelisms, that is, repetitions of syntactic features, on the emotion-sensitive "late positive potential" (LPP) with a cross-modal priming paradigm. Primes were auditory presented nonsense sentences which included grammatical-syntactic parallelisms. Visual targets were positive, neutral, and negative faces, to be classified as emotional or non-emotional by the participants. Electrophysiology revealed diminished LPP amplitudes for positive faces following parallel primes. Thus, our findings suggest that grammatical structure creates an emotional context that facilitates processing of positive emotional information. KW - Language KW - Emotion KW - Priming KW - ERP KW - Late positive potential KW - Structural parallelisms Y1 - 2013 U6 - https://doi.org/10.1016/j.ijpsycho.2012.10.014 SN - 0167-8760 SN - 1872-7697 VL - 87 IS - 1 SP - 28 EP - 34 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kappel, Christian A1 - Friedrich, Thomas A1 - Oberkofler, Vicky A1 - Jiang, Li A1 - Crawford, Tim A1 - Lenhard, Michael A1 - Bäurle, Isabel T1 - Genomic and epigenomic determinants of heat stress-induced transcriptional memory in Arabidopsis JF - Genome biology : biology for the post-genomic era N2 - Background Transcriptional regulation is a key aspect of environmental stress responses. Heat stress induces transcriptional memory, i.e., sustained induction or enhanced re-induction of transcription, that allows plants to respond more efficiently to a recurrent HS. In light of more frequent temperature extremes due to climate change, improving heat tolerance in crop plants is an important breeding goal. However, not all heat stress-inducible genes show transcriptional memory, and it is unclear what distinguishes memory from non-memory genes. To address this issue and understand the genome and epigenome architecture of transcriptional memory after heat stress, we identify the global target genes of two key memory heat shock transcription factors, HSFA2 and HSFA3, using time course ChIP-seq. Results HSFA2 and HSFA3 show near identical binding patterns. In vitro and in vivo binding strength is highly correlated, indicating the importance of DNA sequence elements. In particular, genes with transcriptional memory are strongly enriched for a tripartite heat shock element, and are hallmarked by several features: low expression levels in the absence of heat stress, accessible chromatin environment, and heat stress-induced enrichment of H3K4 trimethylation. These results are confirmed by an orthogonal transcriptomic data set using both de novo clustering and an established definition of memory genes. Conclusions Our findings provide an integrated view of HSF-dependent transcriptional memory and shed light on its sequence and chromatin determinants, enabling the prediction and engineering of genes with transcriptional memory behavior. KW - Transcriptional memory KW - Priming KW - Heat stress KW - HSFA2 KW - HSFA3 KW - Arabidopsis thaliana KW - Histone H3K4 trimethylation KW - ChIP-seq Y1 - 2023 U6 - https://doi.org/10.1186/s13059-023-02970-5 SN - 1474-760X SN - 1465-6906 VL - 24 IS - 1 PB - BioMed Central CY - London ER - TY - JOUR A1 - Sixtus, Elena A1 - Fischer, Martin H. A1 - Lindemann, Oliver T1 - Finger posing primes number comprehension JF - Cognitive processing : international quarterly of cognitive science N2 - Canonical finger postures, as used in counting, activate number knowledge, but the exact mechanism for this priming effect is unclear. Here we dissociated effects of visual versus motor priming of number concepts. In Experiment 1, participants were exposed either to pictures of canonical finger postures (visual priming) or actively produced the same finger postures (motor priming) and then used foot responses to rapidly classify auditory numbers (targets) as smaller or larger than 5. Classification times revealed that manually adopted but not visually perceived postures primed magnitude classifications. Experiment 2 obtained motor priming of number processing through finger postures also with vocal responses. Priming only occurred through canonical and not through non-canonical finger postures. Together, these results provide clear evidence for motor priming of number knowledge. Relative contributions of vision and action for embodied numerical cognition and the importance of canonicity of postures are discussed. KW - Embodied cognition KW - Finger counting KW - Numerical cognition KW - Priming Y1 - 2017 U6 - https://doi.org/10.1007/s10339-017-0804-y SN - 1612-4782 SN - 1612-4790 VL - 18 SP - 237 EP - 248 PB - Springer CY - Heidelberg ER -