TY  - JOUR
A1  - Liu, Hsiang-chin
A1  - Lämke, Jörn
A1  - Lin, Siou-ying
A1  - Hung, Meng-Ju
A1  - Liu, Kuan-Ming
A1  - Charng, Yee-yung
A1  - Bäurle, Isabel
T1  - Distinct heat shock factors and chromatin modifications mediate the organ-autonomous transcriptional memory of heat stress
JF  - The plant journal
N2  - Plants can be primed by a stress cue to mount a faster or stronger activation of defense mechanisms upon subsequent stress. A crucial component of such stress priming is the modified reactivation of genes upon recurring stress; however, the underlying mechanisms of this are poorly understood. Here, we report that dozens of Arabidopsis thaliana genes display transcriptional memory, i.e. stronger upregulation after a recurring heat stress, that lasts for at least 3 days. We define a set of transcription factors involved in this memory response and show that the transcriptional memory results in enhanced transcriptional activation within minutes of the onset of a heat stress cue. Further, we show that the transcriptional memory is active in all tissues. It may last for up to a week, and is associated during this time with histone H3 lysine 4 hypermethylation. This transcriptional memory is cis-encoded, as we identify a promoter fragment that confers memory onto a heterologous gene. In summary, heat-induced transcriptional memory is a widespread and sustained response, and our study provides a framework for future mechanistic studies of somatic stress memory in higher plants.
KW  - epigenetics
KW  - priming
KW  - heat stress
KW  - H3K4 methylation
KW  - transcriptional memory
KW  - Arabidopsis thaliana
KW  - HSF
Y1  - 2018
U6  - https://doi.org/10.1111/tpj.13958
SN  - 0960-7412
SN  - 1365-313X
VL  - 95
IS  - 3
SP  - 401
EP  - 413
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Friedrich, Thomas
A1  - Faivre, Lea
A1  - Bäurle-Lenhard, Isabel
A1  - Schubert, Daniel
T1  - Chromatin-based mechanisms of temperature memory in plants
JF  - Plant, cell & environment : cell physiology, whole-plant physiology, community physiology
N2  - For successful growth and development, plants constantly have to gauge their environment. Plants are capable to monitor their current environmental conditions, and they are also able to integrate environmental conditions over time and store the information induced by the cues. In a developmental context, such an environmental memory is used to align developmental transitions with favourable environmental conditions. One temperature-related example of this is the transition to flowering after experiencing winter conditions, that is, vernalization. In the context of adaptation to stress, such an environmental memory is used to improve stress adaptation even when the stress cues are intermittent. A somatic stress memory has now been described for various stresses, including extreme temperatures, drought, and pathogen infection. At the molecular level, such a memory of the environment is often mediated by epigenetic and chromatin modifications. Histone modifications in particular play an important role. In this review, we will discuss and compare different types of temperature memory and the histone modifications, as well as the reader, writer, and eraser proteins involved.
KW  - chromatin
KW  - cold
KW  - epigenetics
KW  - heat
KW  - memory
KW  - nucleosome remodelling
KW  - polycomb
KW  - priming
KW  - trithorax
Y1  - 2018
U6  - https://doi.org/10.1111/pce.13373
SN  - 0140-7791
SN  - 1365-3040
VL  - 42
IS  - 3
SP  - 762
EP  - 770
PB  - Wiley
CY  - Hoboken
ER  -