TY  - JOUR
A1  - Sarauli, David
A1  - Peters, Kristina
A1  - Xu, Chenggang
A1  - Schulz, Burkhard
A1  - Fattakhova-Rohlfing, Dina
A1  - Lisdat, Fred
T1  - 3D-Electrode architectures for enhanced direct bioelectrocatalysis of pyrroloquinoline quinone-dependent glucose dehydrogenase
JF  - ACS applied materials & interfaces
N2  - We report on the fabrication of a complex electrode architecture for efficient direct bioelectrocatalysis. In the developed procedure, the redox enzyme pyrroloquinoline quinone-dependent glucose dehydrogenase entrapped in a sulfonated polyaniline [poly(2-methoxyaniline-5-sulfonic acid)-co-aniline] was immobilized on macroporous indium tin oxide (macroITO) electrodes. The use of the 3D-conducting scaffold with a large surface area in combination with the conductive polymer enables immobilization of large amounts of enzyme and its efficient communication with the electrode, leading to enhanced direct bioelectrocatalysis. In the presence of glucose, the fabricated bioelectrodes show an exceptionally high direct bioelectrocatalytical response without any additional mediator. The catalytic current is increased more than 200-fold compared to planar ITO electrodes. Together with a high long-term stability (the current response is maintained for >90% of the initial value even after 2 weeks of storage), the transparent 3D macroITO structure with a conductive polymer represents a valuable basis for the construction of highly efficient bioelectronic units, which are useful as indicators for processes liberating glucose and allowing optical and electrochemical transduction.
KW  - 3D electrode structures
KW  - macroITO
KW  - conductive polymer
KW  - PQQ-GDH
KW  - direct bioelectrocatalysis
KW  - bioelectrochemistry
Y1  - 2014
U6  - https://doi.org/10.1021/am5046026
SN  - 1944-8244
VL  - 6
IS  - 20
SP  - 17887
EP  - 17893
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Aksu, Yilmaz
A1  - Frasca, Stefano
A1  - Wollenberger, Ursula
A1  - Driess, Matthias
A1  - Thomas, Arne
T1  - A molecular precursor approach to tunable porous tin-rich indium tin oxide with durable high electrical conductivity for bioelectronic devices
JF  - Chemistry of materials : a publication of the American Chemical Society
N2  - The preparation of porous, i.e., high surface area electrodes from transparent conducting oxides, is a valuable goal in materials chemistry as such electrodes can enable further development of optoelectronic, electrocatalytic, or bioelectronic devices. In this work the first tin-rich mesoporous indium tin oxide is prepared using the molecular heterobimetallic single-source precursor, indium tin tris-tert-butoxide, together with an appropriate structure-directing template, yielding materials with high surface areas and tailorable pore size. The resulting mesoporous tin-rich ITO films show a high and durable electrical conductivity and transparency, making them interesting materials for hosting electroactive biomolecules such as proteins. In fact, its unique performance in bioelectronic applications has been demonstrated by immobilization of high amounts of cytochrome c into the mesoporous film which undergo redox processes directly with the conductive electrode material.
KW  - indium tin oxide ITO
KW  - electrode
KW  - bioelectrochemistry
KW  - device
KW  - cytochrome c
Y1  - 2011
U6  - https://doi.org/10.1021/cm103087p
SN  - 0897-4756
VL  - 23
IS  - 7
SP  - 1798
EP  - 1804
PB  - American Chemical Society
CY  - Washington
ER  -