TY  - JOUR
A1  - Graf, Philipp
A1  - Mantion, Alexandre
A1  - Haase, Andrea
A1  - Thuenemann, Andreas F.
A1  - Masic, Admir
A1  - Meier, Wolfgang P.
A1  - Luch, Andreas
A1  - Taubert, Andreas
T1  - Silicification of peptide-coated silver nanoparticles-A biomimetic soft chemistry approach toward chiral hybrid core-shell materials
JF  - ACS nano
N2  - Silica and silver nanoparticles are relevant materials for new applications in optics, medicine, and analytical chemistry. We have previously reported the synthesis of pH responsive, peptide-templated, chiral silver nanoparticles. The current report shows that peptide-stabilized nanoparticles can easily be coated with a silica shell by exploiting the ability of the peptide coating to hydrolyze silica precursors such as TEOS or TMOS. The resulting silica layer protects the nanoparticles from chemical etching, allows their inclusion in other materials, and renders them biocompatible. Using electron and atomic force microscopy, we show that the silica shell thickness and the particle aggregation can be controlled simply by the reaction time. Small-angle X ray scattering confirms the Ag/peptide@silica core-shell structure. UV-vis and circular dichroism spectroscopy prove the conservation of the silver nanoparticle chirality upon silicification. Biological tests show that the biocompatibility in simple bacterial systems is significantly improved once a silica layer is deposited on the silver particles.
KW  - peptide-templated materials
KW  - silver nanoparticles
KW  - chiral nanoparticles
KW  - Ag/peptide@SiO(2) nanostructures
KW  - core-shell structures
Y1  - 2011
U6  - https://doi.org/10.1021/nn102969p
SN  - 1936-0851
VL  - 5
IS  - 2
SP  - 820
EP  - 833
PB  - American Chemical Society
CY  - Washington
ER  -