TY  - JOUR
A1  - Omidbakhshfard, Mohammad Amin
A1  - Proost, Sebastian
A1  - Fujikura, Ushio
A1  - Müller-Röber, Bernd
T1  - Growth-Regulating Factors (GRFs): A Small Transcription Factor Family with Important Functions in Plant Biology
JF  - Molecular plant
N2  - Growth-regulating factors (GRFs) are plant-specific transcription factors that were originally identified for their roles in stem and leaf development, but recent studies highlight them to be similarly important for other central developmental processes including flower and seed formation, root development, and the coordination of growth processes under adverse environmental conditions. The expression of several GRFs is controlled by microRNA miR396, and the GRF-miRNA396 regulatory module appears to be central to several of these processes. In addition, transcription factors upstream of GRFs and miR396 have been discovered, and gradually downstream target genes of GRFs are being unraveled. Here, we review the current knowledge of the biological functions performed by GRFs and survey available molecular data to illustrate how they exert their roles at the cellular level.
KW  - abiotic stress
KW  - chromatin remodeling
KW  - flower development
KW  - growth regulation
KW  - leaf development
KW  - miRNA
Y1  - 2015
U6  - https://doi.org/10.1016/j.molp.2015.01.013
SN  - 1674-2052
SN  - 1752-9867
VL  - 8
IS  - 7
SP  - 998
EP  - 1010
PB  - Cell Press
CY  - Cambridge
ER  -