TY  - JOUR
A1  - Köker, Latife
A1  - Akçaalan, Reyhan
A1  - Dittmann, Elke
A1  - Albay, Meriç
T1  - Depth profiles of protein-bound microcystin in Küçükçekmece Lagoon
JF  - Toxicon : an international journal devoted to the exchange of knowledge on the poisons derived from the tissues of plants and animals ; official journal of the International Society on Toxinology
N2  - Microcystis is the most commonly found toxic cyanobacterial genus around the world and has a negative impact on the ecosystem. As a predominant producer of the potent hepatotoxin microcystin (MC), the genus causes outbreaks in freshwaters worldwide. Standard analytical methods that are used for the detection of microcystin variants can only measure the free form of microcystin in cells. Since microcystin was found as free and proteinbound forms in the cells, a significant proportion of microcystin is underestimated with analytical methods. The aim of the study was to measure protein-bound microcystins and determine the environmental factors that affect the binding of microcystin to proteins. Samples were taken at depths of surface, 1 m, 5 m, 10 m, 15 m, and 18 m in Kucukcekmece Lagoon to analyze depth profiles of two different microcystin forms from June to September 2012 at regular monthly intervals. Our findings suggest that the most important parameter affecting proteinbound microcystin at surface water is high light. Due to favorable environmental conditions such as temperature, light, and physicochemical parameters, the higher microcystin contents, both free and protein-bound MCs, were found in summer periods.
KW  - Microcystis
KW  - Microcystin
KW  - Protein-bound microcystin
KW  - Mcy gene
KW  - Kucukcekmece Lagoon
Y1  - 2021
U6  - https://doi.org/10.1016/j.toxicon.2021.05.005
SN  - 0041-0101
SN  - 1879-3150
VL  - 198
SP  - 156
EP  - 163
PB  - Elsevier
CY  - Oxford
ER  -