TY  - JOUR
A1  - Schneider, Matthias
A1  - Günter, Christina
A1  - Taubert, Andreas
T1  - Co-deposition of a hydrogel/calcium phosphate hybrid layer on 3D printed poly(lactic acid) scaffolds via dip coating
BT  - Towards Automated Biomaterials Fabrication
JF  - Polymers
N2  - The article describes the surface modification of 3D printed poly(lactic acid) (PLA) scaffolds with calcium phosphate (CP)/gelatin and CP/chitosan hybrid coating layers. The presence of gelatin or chitosan significantly enhances CP co-deposition and adhesion of the mineral layer on the PLA scaffolds. The hydrogel/CP coating layers are fairly thick and the mineral is a mixture of brushite, octacalcium phosphate, and hydroxyapatite. Mineral formation is uniform throughout the printed architectures and all steps (printing, hydrogel deposition, and mineralization) are in principle amenable to automatization. Overall, the process reported here therefore has a high application potential for the controlled synthesis of biomimetic coatings on polymeric biomaterials.
KW  - 3D printing
KW  - dip-coating
KW  - poly(lactic acid)
KW  - PLA
KW  - calcium phosphate
KW  - gelatin
KW  - chitosan
KW  - hydrogel
KW  - calcium phosphate hybrid material
KW  - biomaterials
Y1  - 2018
U6  - https://doi.org/10.3390/polym10030275
SN  - 2073-4360
VL  - 10
IS  - 3
PB  - MDPI
CY  - Basel
ER  -