TY  - JOUR
A1  - Sedaghatmehr, Mastoureh
A1  - Thirumalaikumar, Venkatesh P.
A1  - Kamranfar, Iman
A1  - Marmagne, Anne
A1  - Masclaux-Daubresse, Celine
A1  - Balazadeh, Salma
T1  - A regulatory role of autophagy for resetting the memory of heat stress in plants
JF  - Plant, cell & environment : cell physiology, whole-plant physiology, community physiology
N2  - As sessile life forms, plants are repeatedly confronted with adverse environmental conditions, which can impair development, growth, and reproduction. During evolution, plants have established mechanisms to orchestrate the delicate balance between growth and stress tolerance, to reset cellular biochemistry once stress vanishes, or to keep a molecular memory, which enables survival of a harsher stress that may arise later. Although there are several examples of memory in diverse plants species, the molecular machinery underlying the formation, duration, and resetting of stress memories is largely unknown so far. We report here that autophagy, a central self-degradative process, assists in resetting cellular memory of heat stress (HS) in Arabidopsis thaliana. Autophagy is induced by thermopriming (moderate HS) and, intriguingly, remains high long after stress termination. We demonstrate that autophagy mediates the specific degradation of heat shock proteins at later stages of the thermorecovery phase leading to the accumulation of protein aggregates after the second HS and a compromised heat tolerance. Autophagy mutants retain heat shock proteins longer than wild type and concomitantly display improved thermomemory. Our findings reveal a novel regulatory mechanism for HS memory in plants.
KW  - Arabidopsis
KW  - heat shock proteins
KW  - priming
KW  - resetting
Y1  - 2019
U6  - https://doi.org/10.1111/pce.13426
SN  - 0140-7791
SN  - 1365-3040
VL  - 42
IS  - 3
SP  - 1054
EP  - 1064
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Singh, Rishu Kumar
A1  - Metzler, Ralf
A1  - Sandev, Trifce
T1  - Resetting dynamics in a confining potential
JF  - Journal of physics : A, Mathematical and theoretical
N2  - We study Brownian motion in a confining potential under a constant-rate resetting to a reset position x(0). The relaxation of this system to the steady-state exhibits a dynamic phase transition, and is achieved in a light cone region which grows linearly with time. When an absorbing boundary is introduced, effecting a symmetry breaking of the system, we find that resetting aids the barrier escape only when the particle starts on the same side as the barrier with respect to the origin. We find that the optimal resetting rate exhibits a continuous phase transition with critical exponent of unity. Exact expressions are derived for the mean escape time, the second moment, and the coefficient of variation (CV).
KW  - diffusion
KW  - resetting
KW  - barrier escape
KW  - first-passage
Y1  - 2020
U6  - https://doi.org/10.1088/1751-8121/abc83a
SN  - 1751-8113
SN  - 1751-8121
VL  - 53
IS  - 50
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  -