TY  - GEN
A1  - Bohlken, Jens
A1  - Jacob, Louis
A1  - Schaum, Peter
A1  - Rapp, Michael A.
A1  - Kostev, Karel
T1  - Hip fracture risk in patients with dementia in German primary care practices
T2  - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe
N2  - The aim was to analyze the risk of hip fracture in German primary care patients with dementia. This study included patients aged 65-90 from 1072 primary care practices who were first diagnosed with dementia between 2010 and 2013. Controls were matched (1:1) to cases for age, sex, and type of health insurance. The primary outcome was the diagnosis of hip fracture during the three-year follow-up period. A total of 53,156 dementia patients and 53,156 controls were included. A total of 5.3% of patients and 0.7% of controls displayed hip fracture after three years. Hip fracture occurred more frequently in dementia subjects living in nursing homes than in those living at home (9.2% versus 4.3%). Dementia, residence in nursing homes, and osteoporosis were risk factors for fracture development. Antidementia, antipsychotic, and antidepressant drugs generally had no significant impact on hip fracture risk when prescribed for less than six months. Dementia increased hip fracture risk in German primary care practices.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 395 
KW  - hip fracture
KW  - dementia
KW  - nursing homes
KW  - osteoporosis
KW  - risk factors
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-404526
IS  - 395
ER  - 
TY  - JOUR
A1  - Bohlken, Jens
A1  - Jacob, Louis
A1  - Schaum, Peter
A1  - Rapp, Michael A.
A1  - Kostev, Karel
T1  - Hip fracture risk in patients with dementia in German primary care practices
JF  - Dementia
N2  - The aim was to analyze the risk of hip fracture in German primary care patients with dementia. This study included patients aged 65-90 from 1072 primary care practices who were first diagnosed with dementia between 2010 and 2013. Controls were matched (1:1) to cases for age, sex, and type of health insurance. The primary outcome was the diagnosis of hip fracture during the three-year follow-up period. A total of 53,156 dementia patients and 53,156 controls were included. A total of 5.3% of patients and 0.7% of controls displayed hip fracture after three years. Hip fracture occurred more frequently in dementia subjects living in nursing homes than in those living at home (9.2% versus 4.3%). Dementia, residence in nursing homes, and osteoporosis were risk factors for fracture development. Antidementia, antipsychotic, and antidepressant drugs generally had no significant impact on hip fracture risk when prescribed for less than six months. Dementia increased hip fracture risk in German primary care practices.
KW  - hip fracture
KW  - dementia
KW  - nursing homes
KW  - osteoporosis
KW  - risk factors
Y1  - 2015
U6  - https://doi.org/10.1177/1471301215621854
SN  - 1471-3012
SN  - 1741-2684
VL  - 16
SP  - 853
EP  - 864
PB  - Sage Publ.
CY  - London
ER  - 
TY  - JOUR
A1  - Jacob, Louis
A1  - Rapp, Michael A.
A1  - Kostev, Karel
T1  - Long-term use of benzodiazepines in older patients in Germany
BT  - a retrospective analysis
JF  - Therapeutic Advances in Psychopharmacology
N2  - Background: The purpose of this study was to analyze the prevalence of long-term benzodiazepine use in older adults treated in general and neuropsychiatric practices in Germany. Methods: This study included 32,182 patients over the age of 65 years who received benzodiazepine prescriptions for the first time between January 2010 and December 2014 in general and neuropsychiatric practices in Germany. Follow up lasted until July 2016. The main outcome measure was the proportion of patients treated with benzodiazepines for >6 months. Results: The proportion of patients with benzodiazepine therapy for >6 months increased with age (65-70 years: 12.3%; 71-80 years: 15.5%; 81-90 years: 23.7%; >90 years: 31.6%) but did not differ significantly between men (15.5%) and women (17.1%). The proportion of patients who received benzodiazepines for >6 months was higher among those with sleep disorders (21.1%), depression (20.8%) and dementia (32.1%) than among those with anxiety (15.5%). By contrast, this proportion was lower among people diagnosed with adjustment disorders (7.7%) and back pain (3.8%). Conclusion: Overall, long-term use of benzodiazepines is common in older people, particularly in patients over the age of 80 and in those diagnosed with dementia, sleep disorders, or depression.
KW  - benzodiazepines
KW  - Germany
KW  - long-term use
KW  - older people
KW  - risk factors
Y1  - 2017
U6  - https://doi.org/10.1177/2045125317696454
SN  - 2045-1253
SN  - 2045-1261
VL  - 7
IS  - 6/7
SP  - 191
EP  - 200
PB  - Sage Publ.
CY  - London
ER  -