TY  - JOUR
A1  - Kedracki, Dawid
A1  - Filippov, Sergey K.
A1  - Gour, Nidhi
A1  - Schlaad, Helmut
A1  - Nardin, Corinne
T1  - Formation of DNA-Copolymer Fibrils Through an Amyloid-Like Nucleation Polymerization Mechanism
JF  - Macromolecular rapid communications
N2  - Conjugation of a hydrophobic poly(2-oxazoline) bearing tertiary amide groups along its backbone with a short single stranded nucleotide sequence results in an amphiphilic comb/graft copolymer, which organizes in fibrils upon direct dissolution in water. Supported by circular dichroism, atomic force microscopy, transmission electron microscopy, and scattering data, fibrils are formed through inter- and intramolecular hydrogen bonding between hydrogen accepting amide groups along the polymer backbone and hydrogen donating nucleic acid grafts leading to the formation of hollow tubes.
KW  - DNA copolymers
KW  - fibers
KW  - hydrogen bonding
KW  - nucleation polymerization
KW  - self-assembly
Y1  - 2015
U6  - https://doi.org/10.1002/marc.201400728
SN  - 1022-1336
SN  - 1521-3927
VL  - 36
IS  - 8
SP  - 768
EP  - 773
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Vishnevetskaya, Natalya S.
A1  - Hildebrand, Viet
A1  - Niebuur, Bart-Jan
A1  - Grillo, Isabelle
A1  - Filippov, Sergey K.
A1  - Laschewsky, Andre
A1  - Müller-Buschbaum, Peter
A1  - Papadakis, Christine M.
T1  - Aggregation Behavior of Doubly Thermoresponsive Polysulfobetaine-b-poly(N-isopropylacrylamide) Diblock Copolymers
JF  - Macromolecules : a publication of the American Chemical Society
N2  - A 2-fold thermoresponsive diblock copolymer PSPP430-b-PNIPAM(200) consisting of a zwitterionic polysulfobetaine (PSPP) block and a nonionic poly(N-isopropylacrylamide) (PNIPAM) block is prepared by successive RAFT polymerizations. In aqueous solution, the corresponding homopolymers PSPP and PNIPAM feature both upper and lower critical solution temperature (UCST and LCST) behavior, respectively. The diblock copolymer exhibits thermally induced "schizophrenic" aggregation behavior in aqueous solutions. Moreover, the ion sensitivity of the, cloud point of the zwitterionic PSPP block to both the ionic strength and the nature of the salt offers the possibility to create switchable systems which respond sensitively to changes of the temperature and of the electrolyte type and concentration. The diblock copolymer solutions in D2O are investigated by means of turbidimetry and small-angle neutron scattering (SANS) with respect to the phase behavior and the self-assembled structures in dependence on temperature and electrolyte content. Marked, differences of the aggregation below the UCST-type and above the LCST-type transition are observed. The addition of a small amount of NaBr (0.004 M) does not affect the overall behavior, and only the UCST-type transition and aggregate structures are slightly altered, reflecting the well-known ion sensitivity of the zwitterionic PSPP block.
Y1  - 2016
U6  - https://doi.org/10.1021/acs.macromol.6b01186
SN  - 0024-9297
SN  - 1520-5835
VL  - 49
SP  - 6655
EP  - 6668
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Vishnevetskaya, Natalya S.
A1  - Hildebrand, Viet
A1  - Niebuur, Bart-Jan
A1  - Grillo, Isabelle
A1  - Filippov, Sergey K.
A1  - Laschewsky, Andre
A1  - Müller-Buschbaum, Peter
A1  - Papadakis, Christine M.
T1  - "Schizophrenic" Micelles from Doubly Thermoresponsive Polysulfobetaine-b-poly(N-isopropylmethacrylamide) Diblock Copolymers
JF  - Macromolecules : a publication of the American Chemical Society
Y1  - 2017
U6  - https://doi.org/10.1021/acs.macromol.7b00356
SN  - 0024-9297
SN  - 1520-5835
VL  - 50
SP  - 3985
EP  - 3999
PB  - American Chemical Society
CY  - Washington
ER  -