TY - GEN A1 - Zöller, Gert A1 - Holschneider, Matthias T1 - Reply to “Comment on ‘The Maximum Possible and the Maximum Expected Earthquake Magnitude for Production‐Induced Earthquakes at the Gas Field in Groningen, The Netherlands’ by Gert Zöller and Matthias Holschneider” by Mathias Raschke T2 - Bulletin of the Seismological Society of America Y1 - 2018 U6 - https://doi.org/10.1785/0120170131 SN - 0037-1106 SN - 1943-3573 VL - 108 IS - 2 SP - 1029 EP - 1030 PB - Seismological Society of America CY - Albany ER - TY - GEN A1 - Yin, Yang A1 - Hua, Chen T1 - On chemotaxis systems with saturation growth T2 - Preprint / Universität Potsdam, Institut für Mathematik, Arbeitsgruppe Partiell Y1 - 2007 SN - 1437-739X PB - Univ. CY - Potsdam ER - TY - GEN A1 - Wicha, Sebastian G. A1 - Kees, Martin G. A1 - Solms, Alexander Maximilian A1 - Minichmayr, Iris K. A1 - Kratzer, Alexander A1 - Kloft, Charlotte T1 - TDMx: A novel web-based open-access support tool for optimising antimicrobial dosing regimens in clinical routine T2 - International journal of antimicrobial agents Y1 - 2015 U6 - https://doi.org/10.1016/j.ijantimicag.2014.12.010 SN - 0924-8579 SN - 1872-7913 VL - 45 IS - 4 SP - 442 EP - 444 PB - Elsevier CY - Amsterdam ER - TY - GEN A1 - Weisser, Karin A1 - Stübler, Sabine A1 - Matheis, Walter A1 - Huisinga, Wilhelm T1 - Towards toxicokinetic modelling of aluminium exposure from adjuvants in medicinal products T2 - Regulatory toxicology and pharmacology : official journal of the International Society for Regulatory Toxicology and Pharmacology N2 - As a potentially toxic agent on nervous system and bone, the safety of aluminium exposure from adjuvants in vaccines and subcutaneous immune therapy (SCIT) products has to be continuously reevaluated, especially regarding concomitant administrations. For this purpose, knowledge on absorption and disposition of aluminium in plasma and tissues is essential. Pharmacokinetic data after vaccination in humans, however, are not available, and for methodological and ethical reasons difficult to obtain. To overcome these limitations, we discuss the possibility of an in vitro-in silico approach combining a toxicokinetic model for aluminium disposition with biorelevant kinetic absorption parameters from adjuvants. We critically review available kinetic aluminium-26 data for model building and, on the basis of a reparameterized toxicokinetic model (Nolte et al., 2001), we identify main modelling gaps. The potential of in vitro dissolution experiments for the prediction of intramuscular absorption kinetics of aluminium after vaccination is explored. It becomes apparent that there is need for detailed in vitro dissolution and in vivo absorption data to establish an in vitro-in vivo correlation (IVIVC) for aluminium adjuvants. We conclude that a combination of new experimental data and further refinement of the Nolte model has the potential to fill a gap in aluminium risk assessment. (C) 2017 Elsevier Inc. All rights reserved. KW - Aluminium KW - Aluminium adjuvants KW - Absorption kinetics KW - Toxicokinetic modelling KW - In vitro dissolution Y1 - 2017 U6 - https://doi.org/10.1016/j.yrtph.2017.02.018 SN - 0273-2300 SN - 1096-0295 VL - 88 SP - 310 EP - 321 PB - Elsevier CY - San Diego ER - TY - GEN A1 - Strader, Anne A1 - Schneider, Max A1 - Schorlemmer, Danijel T1 - Erratum zu: Strader, Anne; Schneider, Max; Schorlemmer, Danijel: Prospective and retrospective evaluation of five-year earthquake forecast models for California (Geophysical Journal International, 211 (2017) 1, S. 239 – 251, https://doi.org/10.1093/gji/ggx268) T2 - Geophysical journal international N2 - S-test results for the USGS and RELM forecasts. The differences between the simulated log-likelihoods and the observed log-likelihood are labelled on the horizontal axes, with scaling adjustments for the 40year.retro experiment. The horizontal lines represent the confidence intervals, within the 0.05 significance level, for each forecast and experiment. If this range contains a log-likelihood difference of zero, the forecasted log-likelihoods are consistent with the observed, and the forecast passes the S-test (denoted by thin lines). If the minimum difference within this range does not contain zero, the forecast fails the S-test for that particular experiment, denoted by thick lines. Colours distinguish between experiments (see Table 2 for explanation of experiment durations). Due to anomalously large likelihood differences, S-test results for Wiemer-Schorlemmer.ALM during the 10year.retro and 40year.retro experiments are not displayed. The range of log-likelihoods for the Holliday-et-al.PI forecast is lower than for the other forecasts due to relatively homogeneous forecasted seismicity rates and use of a small fraction of the RELM testing region. Y1 - 2017 U6 - https://doi.org/10.1093/gji/ggx496 SN - 0956-540X SN - 1365-246X VL - 212 IS - 2 SP - 1314 EP - 1314 PB - Oxford Univ. Press CY - Oxford ER - TY - GEN A1 - Quaisser, Erhard T1 - Greewell, D. ; Johnson, P. D., Geombinatorics,2 (1993), 3, S. 61 - 64 BT - Geombinatorics Y1 - 1996 ER - TY - GEN A1 - Quaisser, Erhard T1 - Grünbaum, B., Geombinatorics, 4 (1995), 3, S. 77 - 79 BT - Geombinatorics Y1 - 1995 ER - TY - GEN A1 - Quaisser, Erhard T1 - Coxeter, A. S. M., Linear algebra and its applications, 226-228 (1995), S. 375 - 388 BT - Linear algebra and its applications Y1 - 1995 ER - TY - GEN A1 - Quaisser, Erhard T1 - Quan, L., Journal of mathematical imaging and vision, 5 (1995), S. 263 - 267 BT - Journal of mathematical imaging and vision Y1 - 1995 ER - TY - GEN A1 - Quaisser, Erhard T1 - Jeurissen, R. H., Linear algebra appl., 226/228 (1995), S. 617 - 638 BT - Linear algebra appl. Y1 - 1995 ER -