TY  - JOUR
A1  - Barlow, S. M.
A1  - Greig, J. B.
A1  - Bridges, J. W.
A1  - Carere, A.
A1  - Carpy, A. J.
A1  - Galli, Corrado L.
A1  - Kleiner, J.
A1  - Knudsen, I.
A1  - Koeter, H. B.
A1  - Levy, L. S.
A1  - Madsen, C.
A1  - Mayer, S.
A1  - Narbonne, J. F.
A1  - Pfannkuch, F.
A1  - Prodanchuk, M. G.
A1  - Smith, Mason R.
A1  - Steinberg, Pablo
T1  - Hazard identification by methods of animal-based toxicology
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Bartsch, Ingrid
A1  - Zschaler, Ingrid
A1  - Haseloff, Monika
A1  - Steinberg, Pablo
T1  - Establishment of a long-term culture system for rat colon epithelial cells
N2  - The aim of this study was to establish a long-term culture. system for rat colon epithelia isolaled by incubating a 4-cm-long rat colon segment cut longitudinally with all ethylenediaminetetraacetic acid [disodium salt]- containing buffer, taken up in conditioned medium from the normal rat kidney fibroblast cell line NRK (i.e., the supernatant Of pure NRK cultures), directly plated on mitomycin C-treated NRK cells and subcultured with conditioned medium from NRK cells. Cells started to migrate out of the crypts shortly after plating them on NRK feeder layers. Some of the crypts fell apart during the isolation procedure. whereas the vast majority of them did it within I to 2 Ill after plating. The cells proliferated extremely slowly but continuously over a period of 4 mo and were epithelial because they expressed cytokeratin 19 and were stained by crystal violet at pH 2.8. In conclusion, the experimental system described ill this study allows to maintain rat colon epithelial cells for up to 4 mo in culture and can be used to Study the effects of a variety of tumor-modulating factors on growth and gene expression of normal colon epithelial cells in vitro
Y1  - 2003
UR  - http://www.springerlink.com/content/120498/
U6  - https://doi.org/10.1290/0404035.1
SN  - 1071-2690
ER  - 
TY  - JOUR
A1  - Bluvshtein, Evgenia
A1  - Glass, George
A1  - Volohonsky, Gloria
A1  - Yaakubowitz, Margalit
A1  - Harness, Ella
A1  - Smorodinsky, Nechama
A1  - Seidel, Albrecht
A1  - Frank, Heinz
A1  - Stark, Avishay Abraham
A1  - Steinberg, Pablo
T1  - Inhibition of the hydrolytic and transpeptidatic activities of rat kidney gamma-glutamyltranspeptidase by specific monoclonal antibodies
Y1  - 1999
ER  - 
TY  - JOUR
A1  - Dybing, E.
A1  - Doe, J.
A1  - Groten, J.
A1  - Kleiner, J.
A1  - O'Brien, J.
A1  - Renwick, A. G.
A1  - Schlatter, J.
A1  - Steinberg, Pablo
A1  - Tritschler, A.
A1  - Walker, R.
A1  - Younes, M.
T1  - Hazard characterisation of chemicals in food and diet : dose response, mechanisms and extrapolation issues
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Fuchs, J.
A1  - Teubner, Wera
A1  - Steinberg, Pablo
T1  - The resistance of intestinal epithelial cells towards the transforming activity of 2-hydroxyamino-1-methyl-6- phenylimidazo[4,5-B]pyridine is accompanied by glutathione S-transferase induction
Y1  - 2004
SN  - 0028-1298
ER  - 
TY  - JOUR
A1  - Hacker, Hans-Jörg
A1  - Steinberg, Pablo
A1  - Bannasch, Peter
T1  - Pyruvate kinase isoenzyme shift from L-type to M2-type is a late event in hepatocarcinogenesis induced in rats by a choline-deficient/DL-ethionine supplemented diet
Y1  - 1998
ER  - 
TY  - JOUR
A1  - Hengstler, Jan Georg
A1  - Ringel, M.
A1  - Biefang, Katja
A1  - Hammel, S.
A1  - Milbert, U.
A1  - Gerl, M.
A1  - Klebach, M.
A1  - Diener, B.
A1  - Platt, Karl-Ludwig
A1  - Böttger, Thomas
A1  - Steinberg, Pablo
A1  - Oesch, Franz
T1  - Cultures with cryopreserved hepatocytes : applicability for studies of enzyme induction
Y1  - 2000
ER  - 
TY  - JOUR
A1  - Hengstler, Jan Georg
A1  - Utesch, D.
A1  - Steinberg, Pablo
T1  - Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction
Y1  - 2000
ER  - 
TY  - JOUR
A1  - Hengstler, Jan Georg
A1  - VanDerBurg, Bart
A1  - Steinberg, Pablo
A1  - Oesch, Franz
T1  - Interspecies differences in cancer susceptibility and toxicity
Y1  - 1999
ER  - 
TY  - JOUR
A1  - Herbst, Uta
A1  - Fuchs, Iris Judith
A1  - Teubner, Wera
A1  - Seidel, Albrecht
A1  - Frank, Heinz
A1  - Steinberg, Pablo
T1  - Malignant transformation of human colon epithelial cells by polycyclic aromatic hydrocarbons and heterocyclic aromatic amines
Y1  - 2004
SN  - 0028-1298
ER  -