TY - JOUR A1 - Wendt, Julia A1 - Morriss, Jayne T1 - An examination of intolerance of uncertainty and contingency instruction on multiple indices during threat acquisition and extinction training JF - International journal of psychophysiology : official journal of the International Organization of Psychophysiology N2 - Individuals who score high in self-reported Intolerance of Uncertainty (IU) tend to find uncertainty aversive. Prior research has demonstrated that under uncertainty individuals with high IU display difficulties in updating learned threat associations to safety associations. Importantly, recent research has shown that providing contingency instructions about threat and safety contingencies (i.e. reducing uncertainty) to individuals with high IU promotes the updating of learned threat associations to safety associations. Here we aimed to conceptually replicate IU and contingency instruction-based effects by conducting a secondary analysis of self-reported IU, ratings, skin conductance, and functional magnetic resonance imaging (fMRI) data recorded during uninstructed/instructed blocks of threat acquisition and threat extinction training (n = 48). Generally, no significant associations were observed between self-reported IU and differential responding to learned threat and safety cues for any measure during uninstructed/instructed blocks of threat acquisition and threat extinction training. There was some tentative evidence that higher IU was associated with greater ratings of unpleasantness and arousal to the safety cue after the experiment and greater skin conductance response to the safety cue during extinction generally. Potential explanations for these null effects and directions for future research are discussed. KW - Acquisition KW - Extinction KW - Threat KW - Instructions KW - Intolerance of KW - Uncertainty KW - Skin conductance KW - fMRI Y1 - 2022 U6 - https://doi.org/10.1016/j.ijpsycho.2022.05.005 SN - 0167-8760 SN - 1872-7697 VL - 177 SP - 171 EP - 178 PB - Elsevier CY - Amsterdam [u.a.] ER -