TY  - JOUR
A1  - Bechi, Beatrice
A1  - Herter, Susanne
A1  - McKenna, Shane
A1  - Riley, Christopher
A1  - Leimkühler, Silke
A1  - Turner, Nicholas J.
A1  - Carnell, Andrew J.
T1  - Catalytic bio-chemo and bio-bio tandem oxidation reactions for amide and carboxylic acid synthesis
JF  - Green chemistry : an international journal and green chemistry resource
N2  - A catalytic toolbox for three different water-based one-pot cascades to convert aryl alcohols to amides and acids and cyclic amines to lactams, involving combination of oxidative enzymes (monoamine oxidase, xanthine dehydrogenase, galactose oxidase and laccase) and chemical oxidants (TBHP or Cul(cat)/H2O2) at mild temperatures, is presented. Mutually compatible conditions were found to afford products in good to excellent yields.
Y1  - 2014
U6  - https://doi.org/10.1039/c4gc01321b
SN  - 1463-9262
SN  - 1463-9270
VL  - 16
IS  - 10
SP  - 4524
EP  - 4529
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Bechi, Beatrice
A1  - Herter, Susanne
A1  - McKenna, Shane
A1  - Riley, Christopher
A1  - Leimkühler, Silke
A1  - Turner, Nicholas J.
A1  - Carnell, Andrew J.
T1  - Catalytic bio–chemo and bio–bio tandem oxidation reactions for amide and carboxylic acid synthesis
N2  - A catalytic toolbox for three different water-based one-pot cascades to convert aryl alcohols to amides and acids and cyclic amines to lactams, involving combination of oxidative enzymes (monoamine oxidase, xanthine dehydrogenase, galactose oxidase and laccase) and chemical oxidants (TBHP or CuI(cat)/H2O2) at mild temperatures, is presented. Mutually compatible conditions were found to afford products in good to excellent yields.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 282 
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-99414
ER  - 
TY  - GEN
A1  - McKenna, Shane M.
A1  - Leimkühler, Silke
A1  - Herter, Susanne
A1  - Turner, Nicholas J.
A1  - Carnell, Andrew J.
T1  - Enzyme cascade reactions
BT  - synthesis of furandicarboxylic acid (FDCA) and carboxylic acids using oxidases in tandem
N2  - A one-pot tandem enzyme reaction using galactose oxidase M3–5 and aldehyde oxidase PaoABC was used to convert hydroxymethylfurfural (HMF) to the pure bioplastics precursor FDCA in 74% isolated yield. A range of alcohols was also converted to carboxylic acids in high yield under mild conditions.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 300 
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-102271
SP  - 3271
EP  - 3275
ER  - 
TY  - JOUR
A1  - McKenna, Shane M.
A1  - Leimkühler, Silke
A1  - Herter, Susanne
A1  - Turner, Nicholas J.
A1  - Carnell, Andrew J.
T1  - Enzyme cascade reactions: synthesis of furandicarboxylic acid (FDCA) and carboxylic acids using oxidases in tandem
JF  - Green chemistry : an international journal and green chemistry resource
N2  - A one-pot tandem enzyme reaction using galactose oxidase M3-5 and aldehyde oxidase PaoABC was used to convert hydroxymethylfurfural (HMF) to the pure bioplastics precursor FDCA in 74% isolated yield. A range of alcohols was also converted to carboxylic acids in high yield under mild conditions.
Y1  - 2015
U6  - https://doi.org/10.1039/c5gc00707k
SN  - 1463-9262
SN  - 1463-9270
VL  - 17
IS  - 6
SP  - 3271
EP  - 3275
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Herter, Susanne
A1  - McKenna, Shane M.
A1  - Frazer, Andrew R.
A1  - Leimkühler, Silke
A1  - Carnell, Andrew J.
A1  - Turner, Nicholas J.
T1  - Galactose Oxidase Variants for the Oxidation of Amino Alcohols in Enzyme Cascade Synthesis
JF  - ChemCatChem : heterogeneous & homogeneous & bio- & nano-catalysis ; a journal of ChemPubSoc Europe
N2  - The use of selected engineered galactose oxidase (GOase) variants for the oxidation of amino alcohols to aldehydes under mild conditions in aqueous systems is reported. GOase variant F-2 catalyses the regioselective oxidation of N-carbobenzyloxy (Cbz)-protected 3-amino-1,2-propanediol to the corresponding -hydroxyaldehyde which was then used in an aldolase reaction. Another variant, M3-5, was found to exhibit activity towards free and N-Cbz-protected aliphatic and aromatic amino alcohols allowing the synthesis of lactams such as 3,4-dihydronaphthalen-1(2H)-one, 2-pyrrolidone and valerolactam in one-pot tandem reactions with xanthine dehydrogenase (XDH) or aldehyde oxidase (PaoABC).
KW  - aldehyde oxidase
KW  - amino alcohols
KW  - cascade reactions
KW  - enzyme catalysis
KW  - lactams
Y1  - 2015
U6  - https://doi.org/10.1002/cctc.201500218
SN  - 1867-3880
SN  - 1867-3899
VL  - 7
IS  - 15
SP  - 2313
EP  - 2317
PB  - Wiley-VCH
CY  - Weinheim
ER  -