TY  - JOUR
A1  - Verlinden, Heleen
A1  - Vleugels, Rut
A1  - Marchal, Elisabeth
A1  - Badisco, Liesbeth
A1  - Tobback, Julie
A1  - Pflüger, Hans-Joachim
A1  - Blenau, Wolfgang
A1  - Vanden Broeck, Jozef
T1  - The cloning, phylogenetic relationship and distribution pattern of two new putative GPCR-type octopamine receptors in the desert locust (Schistocerca gregaria)
N2  - The biogenic amine octopamine functions as a neuromodulator, neurotransmitter and neurohormone in insect nervous systems. It plays a prominent role in modulating multiple physiological and behavioural processes in invertebrates. Octopamine exerts its effects by binding to specific receptor proteins that belong to the superfamily of G protein-coupled receptors. We found two partial sequences of putative octopamine receptors in the desert locust Schistocerca gregaria (SgOct alpha R and SgOct beta R) and investigated their transcript levels in males and females of both phases and during the transition between long-term solitarious and gregarious locusts. The transcript levels of SgOctaR are the highest in the central nervous system, whereas those of SgOct beta R are the highest in the flight muscles, followed by the central nervous system. Both SgOct alpha R and SgOct beta R show higher transcript levels in long-term gregarious locusts as compared to solitarious ones. The rise of SgOct beta R transcript levels already appears during the first 4 h of gregarisation, during which also the behavioural changes take place.
Y1  - 2010
UR  - http://www.sciencedirect.com/science/journal/00221910
U6  - https://doi.org/10.1016/j.jinsphys.2010.03.003
SN  - 0022-1910
ER  - 
TY  - JOUR
A1  - Verlinden, Heleen
A1  - Vleugels, Rut
A1  - Marchal, Elisabeth
A1  - Badisco, Liesbeth
A1  - Pflüger, Hans-Joachim
A1  - Blenau, Wolfgang
A1  - Vanden Broeck, Jozef
T1  - The role of octopamine in locusts and other arthropods
N2  - The biogenic amine octopamine and its biological precursor tyramine are thought to be the invertebrate functional homologues of the vertebrate adrenergic transmitters. Octopamine functions as a neuromodulator, neurotransmitter and neurohormone in insect nervous systems and prompts the whole organism to "dynamic action". A growing number of studies suggest a prominent role for octopamine in modulating multiple physiological and behavioural processes in invertebrates, as for example the phase transition in Schistocerca gregaria. Both octopamine and tyramine exert their effects by binding to specific receptor proteins that belong to the superfamily of G protein-coupled receptors. Since these receptors do not appear to be present in vertebrates, they may present very suitable and specific insecticide and acaricide targets. (C) 2010 Elsevier Ltd. All rights reserved.
Y1  - 2010
UR  - http://www.sciencedirect.com/science/journal/00221910
U6  - https://doi.org/10.1016/j.jinsphys.2010.05.018
SN  - 0022-1910
ER  -