TY  - JOUR
A1  - Virta, P.
A1  - Koch, Andreas
A1  - Roslund, M. U.
A1  - Mattjus, P.
A1  - Kleinpeter, Erich
A1  - Kronberg, L.
A1  - Sjoholm, R.
A1  - Klika, Karel D.
T1  - Synthesis, characterisation and theoretical calculations of 2,6-diaminopurine etheno derivatives
N2  - Four derivatives of 2,6-diaminopurine (1) were synthesised and characterised. When 1 was reacted with chloroacetaldehyde, 5-aminoimidazo[2,1- i] purine (2), 9-aminoimidazo[2,1-b]purine (3), 9-aminoimidazo[1,2- a]purine (4) and diimidazo[2,1-b: 2', 1'-i]purine (5) were formed. The purified products (3 - 5) were fully characterised by MS, complete NMR assignments as well as fluorescence and UV spectroscopy. The purified, isolated yields of these products ( 3 - 5) varied from 2.5 to 30%. The relative stability of different tautomers was investigated by theoretical calculations. Fluorescence characteristics are also discussed and compared to the starting material 1 and a reference molecule 2-aminopurine
Y1  - 2005
SN  - 1477-0520
ER  -