TY  - GEN
A1  - Hentrich, Doreen
A1  - Tauer, Klaus
A1  - Espanol, Montserrat
A1  - Ginebra, Maria-Pau
A1  - Taubert, Andreas
T1  - EDTA and NTA effectively tune the mineralization of calcium phosphate from bulk aqueous solution
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - This study describes the effects of nitrilotriacetic acid (NTA) and ethylenediaminotetraacetic acid (EDTA) on themineralization of calciumphosphate from bulk aqueous solution. Mineralization was performed between pH 6 and 9 and with NTA or EDTA concentrations of 0, 5, 10, and 15 mM. X-ray diffraction and infrared spectroscopy show that at low pH, mainly brushite precipitates and at higher pH, mostly hydroxyapatite forms. Both additives alter the morphology of the precipitates. Without additive, brushite precipitates as large plates. With NTA, the morphology changes to an unusual rod-like shape. With EDTA, the edges of the particles are rounded and disk-like particles form. Conductivity and pH measurements suggest that the final products form through several intermediate steps.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1095 
KW  - biomineralization
KW  - biomimetic mineralization
KW  - calcium phosphate
KW  - NTA
KW  - EDTA
KW  - precipitation
KW  - brushite
KW  - hydroxyapatite
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-469186
SN  - 1866-8372
IS  - 1095
ER  - 
TY  - JOUR
A1  - Hentrich, Doreen
A1  - Tauer, Klaus
A1  - Espanol, Montserrat
A1  - Ginebra, Maria-Pau
A1  - Taubert, Andreas
T1  - EDTA and NTA effectively tune the mineralization of calcium phosphate from bulk aqueous solution
JF  - Biomimetics
N2  - This study describes the effects of nitrilotriacetic acid (NTA) and ethylenediaminotetraacetic acid (EDTA) on themineralization of calciumphosphate from bulk aqueous solution. Mineralization was performed between pH 6 and 9 and with NTA or EDTA concentrations of 0, 5, 10, and 15 mM. X-ray diffraction and infrared spectroscopy show that at low pH, mainly brushite precipitates and at higher pH, mostly hydroxyapatite forms. Both additives alter the morphology of the precipitates. Without additive, brushite precipitates as large plates. With NTA, the morphology changes to an unusual rod-like shape. With EDTA, the edges of the particles are rounded and disk-like particles form. Conductivity and pH measurements suggest that the final products form through several intermediate steps.
KW  - biomineralization
KW  - biomimetic mineralization
KW  - calcium phosphate
KW  - NTA
KW  - EDTA
KW  - precipitation
KW  - brushite
KW  - hydroxyapatite
Y1  - 2017
U6  - https://doi.org/10.3390/biomimetics2040024
SN  - 2313-7673
VL  - 2
IS  - 4
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Hentrich, Doreen
A1  - Taabache, Soraya
A1  - Brezesinski, Gerald
A1  - Lange, Nele
A1  - Unger, Wolfgang
A1  - Kuebel, Christian
A1  - Bertin, Annabelle
A1  - Taubert, Andreas
T1  - A Dendritic Amphiphile for Efficient Control of Biomimetic Calcium Phosphate Mineralization
JF  - Macromolecular bioscience
N2  - The phase behavior of a dendritic amphiphile containing a Newkome-type dendron as the hydrophilic moiety and a cholesterol unit as the hydrophobic segment is investigated at the air-liquid interface. The amphiphile forms stable monomolecular films at the airliquid interface on different subphases. Furthermore, the mineralization of calcium phosphate beneath the monolayer at different calcium and phosphate concentrations versus mineralization time shows that at low calcium and phosphate concentrations needles form, whereas flakes and spheres dominate at higher concentrations. Energy-dispersive X-ray spectroscopy, X-ray photoelectron spectroscopy, and electron diffraction confirm the formation of calcium phosphate. High-resolution transmission electron microscopy and electron diffraction confirm the predominant formation of octacalcium phosphate and hydroxyapatite. The data also indicate that the final products form via a complex multistep reaction, including an association step, where nano-needles aggregate into larger flake-like objects.
Y1  - 2017
U6  - https://doi.org/10.1002/mabi.201600524
SN  - 1616-5187
SN  - 1616-5195
VL  - 17
SP  - 2541
EP  - 2548
PB  - Wiley-VCH
CY  - Weinheim
ER  -