TY - JOUR A1 - Leukel, Christian A1 - Lundbye-Jensen, Jesper A1 - Gruber, Markus A1 - Zuur, Abraham T. A1 - Gollhofer, Albert A1 - Taube, Wolfgang T1 - Short-term pressure induced suppression of the short-latency response : a new methodology for investigating stretch reflexes N2 - During experiments involving ischemic nerve block, we noticed that the short-latency response (SLR) of evoked stretches in m. soleus decreased immediately following inflation of a pneumatic cuff surrounding the lower leg. The present study aimed to investigate this short-term effect of pressure application in more detail. Fifty-eight healthy subjects were divided into seven protocols. Unilateral stretches were applied to the calf muscles to elicit a SLR, and bilateral stretches to evoke a subsequent medium-latency response (MLR). Furthermore, H-reflexes and sensory nerve action potentials (SNAPs) were recorded. Additionally, stretches were applied with different velocities and amplitudes. Finally, the SLR was investigated during hopping and in two protocols that modified the ability of the muscle-tendon complex distal to the cuff to stretch. All measurements were performed with deflated and inflated cuff. Results of the protocols were as follows: 1) inflation of the cuff reduced the SLR but not the MLR; 2) the H-reflex, the M-wave, and, 3) SNAPs of n. tibialis remained unchanged with deflated and inflated cuff; 4) the SLR was dependent on the stretch velocity with deflated and also inflated cuff; 5 and 6) the reduction of the SLR by the cuff was dependent on the elastic properties of the muscle-tendon complex distal to the cuff; and 7) the cuff reduced the SLR during hopping. The present results suggest that the cuff did not affect the reflex arc per se. It is proposed that inflation restricted stretch of the muscles underlying the cuff so that most of the length change occurred in the muscle-tendon complex distal to the cuff. As a consequence, the muscle spindles lying within the muscle may be less excited, resulting in a reduced SLR. Due to its applicability in functional tasks, the introduced method can be a useful tool to study afferent feedback in motor control. Y1 - 2009 UR - http://jap.physiology.org/ U6 - https://doi.org/10.1152/japplphysiol.00301.2009 SN - 8750-7587 ER - TY - JOUR A1 - Fimland, Marius S. A1 - Helgerud, Jan A1 - Gruber, Markus A1 - Leivseth, Gunnar A1 - Hoff, Jan T1 - Functional maximal strength training induces neural transfer to single-joint tasks N2 - The purpose of this study was to investigate whether neural adaptations following functional multiple-joint leg press training can induce neural adaptations to the plantar flexor muscles in a single-joint contraction task. Subjects were randomised to a maximal strength training (MST) (n = 10) or a control group (n = 9). MST consisted of 24 sessions (8 weeks) of 4 x 4 repetitions of horizontal leg press using maximal intended velocity in the concentric phase with the movement ending in a plantar flexion. Neural adaptations in the soleus and gastrocnemius medialis (GM) were assessed by surface electromyographic activity and V-waves during maximum voluntary isometric contraction (MVIC), and also by H- reflexes in the soleus during rest and 20% MVIC. One repetition maximum leg press increased by 44 +/- A 14% (mean +/- A SD; P < 0.01). Plantar flexion MVIC increased by 20 +/- A 14% (P < 0.01), accompanied by 13 +/- A 19% (P < 0.05) increase in soleus, but not GM surface electromyography. Soleus V/M-SUP increased by 53 +/- A 66% and in GM by 59 +/- A 64% (P < 0.05). Normalised soleus H-reflexes remained unchanged by training. No changes occurred in the control group. These results suggest that leg press MST can induce neural adaptations in a single-joint plantar flexion MVIC task. Y1 - 2009 UR - http://www.springerlink.com/content/100513 U6 - https://doi.org/10.1007/s00421-009-1096-4 SN - 1439-6319 ER - TY - JOUR A1 - Gruber, Markus A1 - Linnamo, Vesa A1 - Strojnik, Vojko A1 - Rantalainen, Tuomas A1 - Avela, Janne T1 - Excitability at the motoneuron pool and motor cortex is specifically modulated in lengthening compared to isometric contractions N2 - Neural control of muscle contraction seems to be unique during muscle lengthening. The present study aimed to determine the specific sites of modulatory control for lengthening compared with isometric contractions. We used stimulation of the motor cortex and corticospinal tract to observe changes at the spinal and cortical levels. Motor- evoked potentials (MEPs) and cervicomedullary MEPs (CMEPs) were evoked in biceps brachii and brachioradialis during maximal and submaximal lengthening and isometric contractions at the same elbow angle. Sizes of CMEPs and MEPs were lower in lengthening contractions for both muscles ( by similar to 28 and similar to 16%, respectively; P < 0.01), but MEP-to-CMEP ratios increased (by similar to 21%; P < 0.05). These results indicate reduced excitability at the spinal level but enhanced motor cortical excitability for lengthening compared with isometric muscle contractions. Y1 - 2009 UR - http://jn.physiology.org/ U6 - https://doi.org/10.1152/jn.91104.2008 SN - 0022-3077 ER - TY - JOUR A1 - Granacher, Urs A1 - Gruber, Markus A1 - Gollhofer, Albert T1 - Resistance training and neuromuscular performance in seniors N2 - Age-related processes in the neuromuscular and the somatosensory system are responsible for decreases in maximal and explosive force production capacity and deficits in postural control. Thus, the objectives of this study were to investigate the effects of resistance training on strength performance and on postural control in seniors. Forty healthy seniors (67 +/- 1 yrs) participated in this study. Subjects were randomly assigned to a resistance training (n = 20) and a control group (n = 20). Resistance training for the lower extremities lasted for 13 weeks at 80% of the one repetition maximum. Pre and post tests included the measurement of maximal isometric leg extension force with special emphasis on the early part of the force-time-curve and the assessment of static (functional reach test) and dynamic (tandem walk test, platform perturbation) postural control. Resistance training resulted I in an enhanced strength performance with increases I in explosive force exceeding those in maximal strength. Improved performances in the functional reach and in the tandem walk test were observed. Resistance training did not have an effect: on the compensation of platform perturbations. Increases in strength performance can primarily be explained by an improved neural drive of the agonist muscles. The inconsistent effect of resistance training on postural control may be explained by heterogeneity of testing methodology or by the incapability of isolated resisiance training to improve postural control. Y1 - 2009 UR - http://www.thieme-connect.de/ejournals/toc/sportsmed U6 - https://doi.org/10.1055/s-0029-1224178 SN - 0172-4622 ER -