TY  - JOUR
A1  - Hoie, Lars H.
A1  - Sjoholm, Ake
A1  - Guldstrand, Marie
A1  - Zunft, Hans-Joachim Franz
A1  - Lueder, Wolfgang
A1  - Graubaum, Hans-Joachim
A1  - Grünwald, Jörg
T1  - Ultra heat treatment destroys cholesterol-lowering effect of soy protein
JF  - International journal of food sciences and nutrition
N2  - A randomized, placebo-controlled, double-blind clinical study was performed to investigate the dose-dependent response of serum cholesterol after consuming an ultra-heat-treated milk containing a soy protein preparation. Eighty hypercholesterolemic subjects were assigned to one of four study groups receiving 12.5 or 25 g soy protein (active treatment) or casein (placebo) daily over a period of 4 weeks. The trial substances were provided as ready-made, ultra-heated milk preparations. Before and after the treatment, serum concentrations of total, low-density lipoprotein, and high-density lipoprotein cholesterol were determined. Unexpectedly, at the end of the study, low-density lipoprotein cholesterol concentrations were significantly increased compared with baseline in all study groups. The magnitude of this increase (17 - 19%) was similar in all active and placebo study groups. Soy protein supplements previously shown to be effective in reducing serum cholesterol had in this study no such lipid-lowering effect after ultra heat treatment.
KW  - soy
KW  - protein
KW  - cholesterol
KW  - ultra heat treatment
Y1  - 2006
U6  - https://doi.org/10.1080/09637480601009059
SN  - 0963-7486
VL  - 57
SP  - 512
EP  - 519
PB  - Taylor & Francis
CY  - Abingdon
ER  -