TY - JOUR A1 - Freitag, Nils A1 - Weber, Pia Deborah A1 - Sanders, Tanja Christiane A1 - Schulz, Holger A1 - Bloch, Wilhelm A1 - Schumann, Moritz T1 - High-intensity interval training and hyperoxia during chemotherapy BT - A case report about the feasibility, safety and physical functioning in a colorectal cancer patient JF - Medicine N2 - Introduction: We conducted a case study to examine the feasibility and safety of high-intensity interval training (HIIT) with increased inspired oxygen content in a colon cancer patient undergoing chemotherapy. A secondary purpose was to investigate the effects of such training regimen on physical functioning. Case presentation: A female patient (51 years; 49.1 kg; 1.65 m; tumor stage: pT3, pN2a (5/29), pM1a (HEP), L0, V0, R0) performed 8 sessions of HIIT (5 × 3 minutes at 90% of Wmax, separated by 2 minutes at 45% Wmax) with an increased inspired oxygen fraction of 30%. Patient safety, training adherence, cardiorespiratory fitness (peak oxygen uptake and maximal power output during an incremental cycle ergometer test), autonomous nervous function (i.e., heart rate variability during an orthostatic test) as well as questionnaire-assessed quality of life (EORTC QLQ-C30) were evaluated before and after the intervention. No adverse events were reported throughout the training intervention and a 3 months follow-up. While the patient attended all sessions, adherence to total training time was only 51% (102 of 200 minutes; mean training time per session 12:44 min:sec). VO2peak and Wmax increased by 13% (from 23.0 to 26.1 mL min kg−1) and 21% (from 83 to 100 W), respectively. Heart rate variability represented by the root mean squares of successive differences both in supine and upright positions were increased after the training by 143 and 100%, respectively. The EORTC QLQ-C30 score for physical functioning (7.5%) as well as the global health score (10.7%) improved, while social function decreased (17%). Conclusions: Our results show that a already short period of HIIT with concomitant hyperoxia was safe and feasible for a patient undergoing chemotherapy for colon cancer. Furthermore, the low overall training adherence of only 51% and an overall low training time per session (∼13 minutes) was sufficient to induce clinically meaningful improvements in physical functioning. However, this case also underlines that intensity and/or length of the HIIT-bouts might need further adjustments to increase training compliance. KW - carcinoma KW - chemo-toxicity KW - exercise therapy KW - fatigue KW - gastrointestinal cancer KW - heart rate variability KW - high-intensity interval training KW - solid tumor Y1 - 2018 U6 - https://doi.org/10.1097/MD.0000000000011068 SN - 1536-5964 SN - 0025-7974 VL - 97 IS - 24 SP - 1 EP - 7 PB - Lippincott Williams & Wilkins CY - Baltimore, Md. ER - TY - JOUR A1 - Paape, Dario L. J. F. A1 - Hemforth, Barbara A1 - Vasishth, Shravan T1 - Processing of ellipsis with garden-path antecedents in French and German BT - Evidence from eye tracking JF - PLoS ONE N2 - In a self-paced reading study on German sluicing, Paape (Paape, 2016) found that reading times were shorter at the ellipsis site when the antecedent was a temporarily ambiguous garden-path structure. As a post-hoc explanation of this finding, Paape assumed that the antecedent’s memory representation was reactivated during syntactic reanalysis, making it easier to retrieve. In two eye tracking experiments, we subjected the reactivation hypothesis to further empirical scrutiny. Experiment 1, carried out in French, showed no evidence in favor in the reactivation hypothesis. Instead, results for one out of the three types of garden-path sentences that were tested suggest that subjects sometimes failed to resolve the temporary ambiguity in the antecedent clause, and subsequently failed to resolve the ellipsis. The results of Experiment 2, a conceptual replication of Paape’s (Paape, 2016) original study carried out in German, are compatible with the reactivation hypothesis, but leave open the possibility that the observed speedup for ambiguous antecedents may be due to occasional retrievals of an incorrect structure. KW - verb-phrase ellipsis KW - lingering misinterpretation KW - sentence comprehension KW - memory KW - ambiguities KW - activation KW - hypothesis KW - discourse KW - clauses Y1 - 2018 U6 - https://doi.org/10.1371/journal.pone.0198620 SN - 1932-6203 VL - 13 IS - 6 SP - 1 EP - 46 PB - PLOS CY - San Francisco ER - TY - JOUR A1 - Gatzhammer, Stefan T1 - Kardinal Franz Ehrle SJ und die Römische Frage JF - Römische Quartalschrift für Christliche Altertumskunde und Kirchengeschichte N2 - Cardinal Franz Ehrle SJ and the Roman Question. The author Stefan Gatzhammer examines the view of the Jesuit, scientific and cardinal Franz Ehrle (1845-1934) on the Roman Question as the open conflict between Italy and the Holy See that worsened after the outbreak of the First World War. As redactor of the "Stimmen der Zeit", Franz Ehrle took up the public debate in Munich from 1916, which was attentively registered in Italy. In particular, the author examines how far Ehrle, with his pragmatic and legally justified proposal for a minimal territorial solution, can be seen as an intellectual author of the State of the Vatican City newly established in 1929 by the Lateran Treaties. KW - Römische Frage KW - Vatikanstaat KW - Kardinal Franz Ehrle KW - Geschichte Italiens im 20. Jahrhundert KW - Lateranverträge 1929 Y1 - 2018 UR - https://www.herder.de/rq/hefte/archiv/112-2017/3-4-2017/kardinal-franz-ehrle-sj-und-die-roemische-frage/ SN - 0035-7812 VL - 112 IS - 3-4 SP - 210 EP - 229 PB - Herder CY - Rom ; Freiburg, Br. ; Wien ER - TY - JOUR A1 - Wernert, Yann T1 - PESCO und die EU-Integration JF - WeltTrends : das außenpolitische Journal Y1 - 2018 SN - 978-3-945878-94-1 SN - 0944-8101 VL - 26 IS - 141 SP - 56 EP - 60 PB - WeltTrends CY - Potsdam ER - TY - JOUR A1 - Zantke, Michael T1 - Die 68er-Bewegung und die Neue Rechte JF - WeltTrends : das außenpolitische Journal Y1 - 2018 SN - 978-3-945878-94-1 SN - 0944-8101 VL - 26 IS - 141 SP - 40 EP - 45 PB - WeltTrends CY - Potsdam ER - TY - JOUR A1 - Dornfeldt, Matthias T1 - Oslo zwischen Berlin und Moskau BT - Norwegens ausbalancierte Erdöl- und Erdgaspolitik JF - Welt-Trends : das außenpolitische Journal Y1 - 2018 SN - 978-3-945878-85-9 SN - 0944-8101 VL - 26 IS - 140 SP - 40 EP - 44 PB - WeltTrends CY - Potsdam ER - TY - JOUR A1 - Fischer, Martin H. T1 - Why Numbers Are Embodied Concepts JF - Frontiers in Psychology KW - arithmetic KW - numerical cognition KW - number concepts KW - embodied cognition KW - philosophy of science Y1 - 2018 U6 - https://doi.org/10.3389/fpsyg.2017.02347 SN - 1664-1078 VL - 8 SP - 1 EP - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Wippert, Pia-Maria A1 - Wiebking, Christine T1 - Stress and Alterations in the Pain Matrix BT - A Biopsychosocial Perspective on Back Pain and Its Prevention and Treatment JF - International Journal of Environmental Research and Public Health N2 - The genesis of chronic pain is explained by a biopsychosocial model. It hypothesizes an interdependency between environmental and genetic factors provoking aberrant long-term changes in biological and psychological regulatory systems. Physiological effects of psychological and physical stressors may play a crucial role in these maladaptive processes. Specifically, long-term demands on the stress response system may moderate central pain processing and influence descending serotonergic and noradrenergic signals from the brainstem, regulating nociceptive processing at the spinal level. However, the underlying mechanisms of this pathophysiological interplay still remain unclear. This paper aims to shed light on possible pathways between physical (exercise) and psychological stress and the potential neurobiological consequences in the genesis and treatment of chronic pain, highlighting evolving concepts and promising research directions in the treatment of chronic pain. Two treatment forms (exercise and mindfulness-based stress reduction as exemplary therapies), their interaction, and the dose-response will be discussed in more detail, which might pave the way to a better understanding of alterations in the pain matrix and help to develop future prevention and therapeutic concepts KW - stress KW - allostatic load KW - relaxation KW - back pain KW - chronic pain KW - physical activity KW - exercise KW - neuroplasticity KW - pain matrix Y1 - 2018 U6 - https://doi.org/10.3390/ijerph15040785 SN - 1660-4601 SN - 1661-7827 VL - 15 IS - 4 SP - 1 EP - 11 PB - MDPI AG CY - Basel ER - TY - JOUR A1 - Fliesser, Michael A1 - De Witt Huberts, Jessie A1 - Wippert, Pia-Maria T1 - Education, job position, income or multidimensional indices? BT - Associations between different socioeconomic status indicators and chronic low back pain in a German sample: a longitudinal field study JF - BMJ Open N2 - Objective: To investigate associations between socioeconomic status (SES) indicators (education, job position, income, multidimensional index) and the genesis of chronic low back pain (CLBP). Design: Longitudinal field study (baseline and 6-month follow-up). Setting: Four medical clinics across Germany. Participants: 352 people were included according to the following criteria: (1) between 18 and 65 years of age, (2) intermittent pain and (3) an understanding of the study and the ability to answer a questionnaire without help. Exclusion criteria were: (1) pregnancy, (2) inability to stand upright, (3) inability to give sick leave information, (4) signs of serious spinal pathology, (5) acute pain in the past 7 days or (6) an incomplete SES indicators questionnaire. Outcome measures: Subjective intensity and disability of CLBP. Results: Analysis showed that job position was the best single predictor of CLBP intensity, followed by a multidimensional index. Education and income had no significant association with intensity. Subjective disability was best predicted by job position, succeeded by the multidimensional index and education, while income again had no significant association. Conclusion: The results showed that SES indicators have different strong associations with the genesis of CLBP and should therefore not be used interchangeably. Job position was found to be the single most important indicator. These results could be helpful in the planning of back pain care programmes, but in general, more research on the relationship between SES and health outcomes is needed. Y1 - 2018 U6 - https://doi.org/10.1136/bmjopen-2017-020207 SN - 2044-6055 VL - 8 SP - 1 EP - 7 PB - BMJ Publishing Group CY - London ER - TY - JOUR A1 - Chaabene, Helmi A1 - Negra, Yassine A1 - Bouguezzi, Raja A1 - Capranica, Laura A1 - Franchini, Emerson A1 - Prieske, Olaf A1 - Hbacha, Hamdi A1 - Granacher, Urs T1 - Tests for the Assessment of Sport-Specific Performance in Olympic Combat Sports BT - A Systematic Review With Practical Recommendations JF - Frontiers in Physiology N2 - The regular monitoring of physical fitness and sport-specific performance is important in elite sports to increase the likelihood of success in competition. This study aimed to systematically review and to critically appraise the methodological quality, validation data, and feasibility of the sport-specific performance assessment in Olympic combat sports like amateur boxing, fencing, judo, karate, taekwondo, and wrestling. A systematic search was conducted in the electronic databases PubMed, Google-Scholar, and Science-Direct up to October 2017. Studies in combat sports were included that reported validation data (e.g., reliability, validity, sensitivity) of sport-specific tests. Overall, 39 studies were eligible for inclusion in this review. The majority of studies (74%) contained sample sizes <30 subjects. Nearly, 1/3 of the reviewed studies lacked a sufficient description (e.g., anthropometrics, age, expertise level) of the included participants. Seventy-two percent of studies did not sufficiently report inclusion/exclusion criteria of their participants. In 62% of the included studies, the description and/or inclusion of a familiarization session (s) was either incomplete or not existent. Sixty-percent of studies did not report any details about the stability of testing conditions. Approximately half of the studies examined reliability measures of the included sport-specific tests (intraclass correlation coefficient [ICC] = 0.43–1.00). Content validity was addressed in all included studies, criterion validity (only the concurrent aspect of it) in approximately half of the studies with correlation coefficients ranging from r = −0.41 to 0.90. Construct validity was reported in 31% of the included studies and predictive validity in only one. Test sensitivity was addressed in 13% of the included studies. The majority of studies (64%) ignored and/or provided incomplete information on test feasibility and methodological limitations of the sport-specific test. In 28% of the included studies, insufficient information or a complete lack of information was provided in the respective field of the test application. Several methodological gaps exist in studies that used sport-specific performance tests in Olympic combat sports. Additional research should adopt more rigorous validation procedures in the application and description of sport-specific performance tests in Olympic combat sports. KW - martial arts KW - validity KW - sensitivity KW - methodological quality KW - specific assessment Y1 - 2018 U6 - https://doi.org/10.3389/fphys.2018.00386 SN - 1664-042X VL - 9 SP - 1 EP - 18 PB - Frontiers Research Foundation CY - Lausanne ER -