TY  - JOUR
A1  - Brzezinka, Krzysztof
A1  - Altmann, Simone
A1  - Czesnick, Hjördis
A1  - Nicolas, Philippe
A1  - Gorka, Michal
A1  - Benke, Eileen
A1  - Kabelitz, Tina
A1  - Jähne, Felix
A1  - Graf, Alexander
A1  - Kappel, Christian
A1  - Bäurle, Isabel
T1  - Arabidopsis FORGETTER1 mediates stress-induced chromatin memory through nucleosome remodeling
JF  - eLife
N2  - Plants as sessile organisms can adapt to environmental stress to mitigate its adverse effects. As part of such adaptation they maintain an active memory of heat stress for several days that promotes a more efficient response to recurring stress. We show that this heat stress memory requires the activity of the FORGETTER1 (FGT1) locus, with fgt1 mutants displaying reduced maintenance of heat-induced gene expression. FGT1 encodes the Arabidopsis thaliana orthologue of Strawberry notch (Sno), and the protein globally associates with the promoter regions of actively expressed genes in a heat-dependent fashion. FGT1 interacts with chromatin remodelers of the SWI/ SNF and ISWI families, which also display reduced heat stress memory. Genomic targets of the BRM remodeler overlap significantly with FGT1 targets. Accordingly, nucleosome dynamics at loci with altered maintenance of heat-induced expression are affected in fgt1. Together, our results suggest that by modulating nucleosome occupancy, FGT1 mediates stress-induced chromatin memory.
Y1  - 2016
U6  - https://doi.org/10.7554/eLife.17061
SN  - 2050-084X
VL  - 5
PB  - eLife Sciences Publications
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Nicolas, Philippe
A1  - Lecourieux, David
A1  - Kappel, Christian
A1  - Cluzet, Stephanie
A1  - Cramer, Grant
A1  - Delrot, Serge
A1  - Lecourieux, Fatma
T1  - The basic leucine zipper transcription factor abscisic acid responseelement-binding factor 2 is an important transcriptional regulator ofabscisic acid-dependent grape berry ripening processes
JF  - Plant physiology : an international journal devoted to physiology, biochemistry, cellular and molecular biology, biophysics and environmental biology of plants
N2  - In grape (Vitis vinifera), abscisic acid (ABA) accumulates during fruit ripening and is thought to play a pivotal role in this process, but the molecular basis of this control is poorly understood. This work characterizes ABSCISIC ACID RESPONSE ELEMENT-BINDING FACTOR2 (VvABF2), a grape basic leucine zipper transcription factor belonging to a phylogenetic subgroup previously shown to be involved in ABA and abiotic stress signaling in other plant species. VvABF2 transcripts mainly accumulated in the berry, from the onset of ripening to the harvesting stage, and were up-regulated by ABA. Microarray analysis of transgenic grape cells overexpressing VvABF2 showed that this transcription factor up-regulates and/or modifies existing networks related to ABA responses. In addition, grape cells overexpressing VvABF2 exhibited enhanced responses to ABA treatment compared with control cells. Among the VvABF2-mediated responses highlighted in this study, the synthesis of phenolic compounds and cell wall softening were the most strongly affected. VvABF2 overexpression strongly increased the accumulation of stilbenes that play a role in plant defense and human health (resveratrol and piceid). In addition, the firmness of fruits from tomato (Solanum lycopersicum) plants overexpressing VvABF2 was strongly reduced. These data indicate that VvABF2 is an important transcriptional regulator of ABA-dependent grape berry ripening.
Y1  - 2014
U6  - https://doi.org/10.1104/pp.113.231977
SN  - 0032-0889
SN  - 1532-2548
VL  - 164
IS  - 1
SP  - 365
EP  - 383
PB  - American Society of Plant Physiologists
CY  - Rockville
ER  -