TY  - JOUR
A1  - Cuong Nguyen Huu, 
A1  - Kappel, Christian
A1  - Keller, Barbara
A1  - Sicard, Adrien
A1  - Takebayashi, Yumiko
A1  - Breuninger, Holger
A1  - Nowak, Michael D.
A1  - Bäurle, Isabel
A1  - Himmelbach, Axel
A1  - Burkart, Michael
A1  - Ebbing-Lohaus, Thomas
A1  - Sakakibara, Hitoshi
A1  - Altschmied, Lothar
A1  - Conti, Elena
A1  - Lenhard, Michael
T1  - Presence versus absence of CYP734A50 underlies the style-length dimorphism in primroses
JF  - eLife
N2  - Heterostyly is a wide-spread floral adaptation to promote outbreeding, yet its genetic basis and evolutionary origin remain poorly understood. In Primula (primroses), heterostyly is controlled by the S-locus supergene that determines the reciprocal arrangement of reproductive organs and incompatibility between the two morphs. However, the identities of the component genes remain unknown. Here, we identify the Primula CYP734A50 gene, encoding a putative brassinosteroid-degrading enzyme, as the G locus that determines the style-length dimorphism. CYP734A50 is only present on the short-styled S-morph haplotype, it is specifically expressed in S-morph styles, and its loss or inactivation leads to long styles. The gene arose by a duplication specific to the Primulaceae lineage and shows an accelerated rate of molecular evolution. Thus, our results provide a mechanistic explanation for the Primula style-length dimorphism and begin to shed light on the evolution of the S-locus as a prime model for a complex plant supergene.
Y1  - 2016
U6  - https://doi.org/10.7554/eLife.17956
SN  - 2050-084X
VL  - 5
PB  - eLife Sciences Publications
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Fujikura, Ushio
A1  - Elsaesser, Lore
A1  - Breuninger, Holger
A1  - Sanchez-Rodriguez, Clara
A1  - Ivakov, Alexander
A1  - Laux, Thomas
A1  - Findlay, Kim
A1  - Persson, Staffan
A1  - Lenhard, Michael
T1  - Atkinesin-13A modulates cell-wall synthesis and cell expansion in arabidopsis thaliana via the THESEUS1 pathway
JF  - PLoS Genetics : a peer-reviewed, open-access journal
N2  - Growth of plant organs relies on cell proliferation and expansion. While an increasingly detailed picture about the control of cell proliferation is emerging, our knowledge about the control of cell expansion remains more limited. We demonstrate the internal-motor kinesin AtKINESIN-13A (AtKIN13A) limits cell expansion and cell size in Arabidopsis thaliana, ion atkinl3a mutants forming larger petals with larger cells. The homolog, AtKINESIN-13B, also affects cell expansion and double mutants display growth, gametophytic and early embryonic defects, indicating a redundant role of he two genes. AtKIN13A is known to depolymerize microtubules and influence Golgi motility and distribution. Consistent his function, AtKIN13A interacts genetically with ANGUSTIFOLIA, encoding a regulator of Golgi dynamics. Reduced AtIGN13A activity alters cell wall structure as assessed by Fourier-transformed infrared-spectroscopy and triggers signalling he THESEUS1-dependent cell-wall integrity pathway, which in turn promotes the excess cell expansion in the atkinl3a mutant. Thus, our results indicate that the intracellular activity of AtKIN13A regulates cell expansion and wall architecture via THESEUS1, providing a compelling case of interplay between cell wall integrity sensing and expansion.
Y1  - 2014
U6  - https://doi.org/10.1371/journal.pgen.1004627
SN  - 1553-7390
SN  - 1553-7404
VL  - 10
IS  - 9
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Lohmann, Daniel
A1  - Stacey, Nicola
A1  - Breuninger, Holger
A1  - Jikumaru, Yusuke
A1  - Müller, Dörte
A1  - Sicard, Adrien
A1  - Leyser, Ottoline
A1  - Yamaguchi, Shinjiro
A1  - Lenhard, Michael
T1  - SLOW MOTION is required for within-plant auxin homeostasis and normal timing of lateral organ initiation at the shoot meristem in Arabidopsis
Y1  - 2010
SN  - 1040-4651
ER  - 
TY  - JOUR
A1  - Breuninger, Holger
A1  - Lenhard, Michael
T1  - Control of tissue and organ growth in plants
Y1  - 2010
SN  - 0070-2153
ER  - 
TY  - JOUR
A1  - Eriksson, Sven
A1  - Stransfeld, Lena
A1  - Adamski, Nikolai Maria
A1  - Breuninger, Holger
A1  - Lenhard, Michael
T1  - KLUH/CYP78A5-dependent growth signaling coordinates floral organ growth in Arabidopsis
Y1  - 2010
SN  - 0960-9822
ER  -