TY  - JOUR
A1  - Schmälzlin, Elmar Gerd
A1  - Moralejo, Benito
A1  - Gersonde, Ingo
A1  - Schleusener, Johannes
A1  - Darvin, Maxim E.
A1  - Thiede, Gisela
A1  - Roth, Martin M.
T1  - Nonscanning large-area Raman imaging for ex vivo/in vivo skin cancer discrimination
JF  - Journal of biomedical optics
N2  - Imaging Raman spectroscopy can be used to identify cancerous tissue. Traditionally, a step-by-step scanning of the sample is applied to generate a Raman image, which, however, is too slow for routine examination of patients. By transferring the technique of integral field spectroscopy (IFS) from astronomy to Raman imaging, it becomes possible to record entire Raman images quickly within a single exposure, without the need for a tedious scanning procedure. An IFS-based Raman imaging setup is presented, which is capable of measuring skin ex vivo or in vivo. It is demonstrated how Raman images of healthy and cancerous skin biopsies were recorded and analyzed. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License.
KW  - Raman spectroscopy
KW  - cancer diagnosis
KW  - Raman imaging
KW  - multichannel
KW  - astronomy
KW  - epidermis
KW  - dermis
Y1  - 2018
U6  - https://doi.org/10.1117/1.JBO.23.10.105001
SN  - 1083-3668
SN  - 1560-2281
VL  - 23
IS  - 10
PB  - SPIE
CY  - Bellingham
ER  - 
TY  - JOUR
A1  - Weilbacher, Peter Michael
A1  - Monreal-Ibero, Ana
A1  - Verhamme, Anne
A1  - Sandin, Christer
A1  - Steinmetz, Matthias
A1  - Kollatschny, Wolfram
A1  - Krajnovic, Davor
A1  - Kamann, Sebastian
A1  - Roth, Martin M.
A1  - Erroz-Ferrer, Santiago
A1  - Marino, Raffaella Anna
A1  - Maseda, Michael V.
A1  - Wendt, Martin
A1  - Bacon, Roland
A1  - Dreizler, Stefan
A1  - Richard, Johan
A1  - Wisotzki, Lutz
T1  - Lyman-continuum leakage as dominant source of diffuse ionized gas in the Antennae galaxy
JF  - Astronomy and astrophysics : an international weekly journal
N2  - The Antennae galaxy (NGC 4038/39) is the closest major interacting galaxy system and is therefore often studied as a merger prototype. We present the first comprehensive integral field spectroscopic dataset of this system, observed with the MUSE instrument at the ESO VLT. We cover the two regions in this system which exhibit recent star formation: the central galaxy interaction and a region near the tip of the southern tidal tail. In these fields, we detect H II regions and diffuse ionized gas to unprecedented depth. About 15% of the ionized gas was undetected by previous observing campaigns. This newly detected faint ionized gas is visible everywhere around the central merger, and shows filamentary structure. We estimate diffuse gas fractions of about 60% in the central field and 10% in the southern region. We are able to show that the southern region contains a significantly different population of H II regions, showing fainter luminosities. By comparing H II region luminosities with the HST catalog of young star clusters in the central field, we estimate that there is enough Lyman-continuum leakage in the merger to explain the amount of diffuse ionized gas that we detect. We compare the Lyman-continuum escape fraction of each H II region against emission line ratios that are sensitive to the ionization parameter. While we find no systematic trend between these properties, the most extreme line ratios seem to be strong indicators of density bounded ionization. Extrapolating the Lyman-continuum escape fractions to the southern region, we conclude that simply from the comparison of the young stellar populations to the ionized gas there is no need to invoke other ionization mechanisms than Lyman-continuum leaking H II regions for the diffuse ionized gas in the Antennae.
KW  - galaxies: interactions
KW  - galaxies: individual: NGC 4038, NGC 4039
KW  - galaxies: ISM
KW  - ISM: structure
KW  - H II regions
Y1  - 2018
U6  - https://doi.org/10.1051/0004-6361/201731669
SN  - 1432-0746
VL  - 611
PB  - EDP Sciences
CY  - Les Ulis
ER  -