TY  - JOUR
A1  - Bollier, Norbert
A1  - Sicard, Adrien
A1  - Leblond, Julie
A1  - Latrasse, David
A1  - Gonzalez, Nathalie
A1  - Gevaudant, Frederic
A1  - Benhamed, Moussa
A1  - Raynaud, Cecile
A1  - Lenhard, Michael
A1  - Chevalier, Christian
A1  - Hernould, Michel
A1  - Delmas, Frederic
T1  - At-MINI ZINC FINGER2 and Sl-INHIBITOR OF MERISTEM ACTIVITY, a Conserved Missing Link in the Regulation of Floral Meristem Termination in Arabidopsis and Tomato
JF  - The plant cell
N2  - In angiosperms, the gynoecium is the last structure to develop within the flower due to the determinate fate of floral meristem (FM) stem cells. The maintenance of stem cell activity before its arrest at the stage called FM termination affects the number of carpels that develop. The necessary inhibition at this stage of WUSCHEL (WUS), which is responsible for stem cell maintenance, involves a two-step mechanism. Direct repression mediated by the MADS domain transcription factor AGAMOUS (AG), followed by indirect repression requiring the C2H2 zinc-finger protein KNUCKLES (KNU), allow for the complete termination of floral stem cell activity. Here, we show that Arabidopsis thaliana MINI ZINC FINGER2 (AtMIF2) and its homolog in tomato (Solanum lycopersicum), INHIBITOR OF MERISTEM ACTIVITY (SlIMA), participate in the FM termination process by functioning as adaptor proteins. AtMIF2 and SlIMA recruit AtKNU and SlKNU, respectively, to form a transcriptional repressor complex together with TOPLESS and HISTONE DEACETYLASE19. AtMIF2 and SlIMA bind to the WUS and SIWUS loci in the respective plants, leading to their repression. These results provide important insights into the molecular mechanisms governing (FM) termination and highlight the essential role of AtMIF2/SlIMA during this developmental step, which determines carpel number and therefore fruit size.
Y1  - 2018
U6  - https://doi.org/10.1105/tpc.17.00653
SN  - 1040-4651
SN  - 1532-298X
VL  - 30
IS  - 1
SP  - 83
EP  - 100
PB  - American Society of Plant Physiologists
CY  - Rockville
ER  -