TY  - JOUR
A1  - Gilles, Maria
A1  - Otto, Henrike
A1  - Wolf, Isabell A. C.
A1  - Scharnholz, Barbara
A1  - Peus, Verena
A1  - Schredl, Michael
A1  - Suetterlin, Marc W.
A1  - Witt, Stephanie H.
A1  - Rietschel, Marcella
A1  - Laucht, Manfred
A1  - Deuschle, Michael
T1  - Maternal hypothalamus-pituitary-adrenal (HPA) system activity and stress measures at birth
JF  - Psychoneuroendocrinology
N2  - Background: Prenatal maternal stress might be a risk for the developing fetus and may have long-lasting effects on child and adult vulnerability to somatic and psychiatric disease. Over-exposure of the unborn to excess glucocorticoids and subsequent alteration of fetal development is hypothesized to be one of the key mechanisms linking prenatal stress with negative child outcome. Methods: In this prospective longitudinal study, mothers-to-be (n = 405) in late pregnancy (36.8 +/- 1.9 weeks of gestational age) and their singleton neonates were studied. We investigated the impact of different prenatal stress indices derived from six stress variables (perceived stress, specific prenatal worries, negative life events, symptoms of depression, trait anxiety, neuroticism) and diurnal maternal saliva cortisol secretion on gestational age and anthropometric measures at birth.
KW  - Early life stress
KW  - Gestational age
KW  - Anthropometric measures at birth
KW  - Cortisol
KW  - Prenatal distress
KW  - Pregnancy
Y1  - 2018
U6  - https://doi.org/10.1016/j.psyneuen.2018.04.022
SN  - 0306-4530
VL  - 94
SP  - 152
EP  - 161
PB  - Elsevier
CY  - Oxford
ER  -