50287
2019
2019
eng
288
296
9
2
109
article
Oxford Univ. Press
Oxford
1
2019-02-05
2019-02-05
--
Potential effects of reduced red meat compared with increased fiber intake on glucose metabolism and liver fat content
Background: Epidemiological studies suggest that an increased red meat intake is associated with a higher risk of type 2 diabetes, whereas an increased fiber intake is associated with a lower risk. Objectives: We conducted an intervention study to investigate the effects of these nutritional factors on glucose and lipid metabolism, body-fat distribution, and liver fat content in subjects at increased risk of type 2 diabetes. Methods: This prospective, randomized, and controlled dietary intervention study was performed over 6 mo. All groups decreased their daily caloric intake by 400 kcal. The "control" group (N = 40) only had this requirement. The "no red meat" group (N = 48) in addition aimed to avoid the intake of red meat, and the "fiber" group (N = 44) increased intake of fibers to 40 g/d. Anthropometric parameters and frequently sampled oral glucose tolerance tests were performed before and after intervention. Body-fat mass and distribution, liver fat, and liver iron content were assessed by MRI and single voxel proton magnetic resonance spectroscopy. Results: Participants in all groups lost weight (mean 3.3 +/- 0.5 kg, P < 0.0001). Glucose tolerance and insulin sensitivity improved (P < 0.001), and body and visceral fat mass decreased in all groups (P < 0.001). These changes did not differ between groups. Liver fat content decreased significantly (P < 0.001) with no differences between the groups. The decrease in liver fat correlated with the decrease in ferritin during intervention (r(2) = 0.08, P = 0.0021). This association was confirmed in an independent lifestyle intervention study (Tuebingen Lifestyle Intervention Program, N = 229, P = 0.0084). Conclusions: Our data indicate that caloric restriction leads to a marked improvement in glucose metabolism and body-fat composition, including liver-fat content. The marked reduction in liver fat might be mediated via changes in ferritin levels. In the context of caloric restriction, there seems to be no additional beneficial impact of reduced red meat intake and increased fiber intake on the improvement in cardiometabolic risk parameters. This trial was registered at clinicaltrials.gov as NCT03231839.
The American journal of clinical nutrition : a publication of the American Society for Nutrition, Inc.
a randomized and controlled dietary intervention study
10.1093/ajcn/nqy307
30721948
0002-9165
1938-3207
wos:2019
WOS:000460615600008
Willmann, C (reprint author), Univ Hosp Tubingen, Dept Internal Med 4, Tubingen, Germany.; Willmann, C (reprint author), Univ Tubingen, Inst Diabet Res & Metab Dis, Helmholtz Ctr Munich, Tubingen, Germany., caroline.willmann@med.uni-tuebingen.de
German Federal Ministry of Education and Research (BMBF)Federal Ministry of Education & Research (BMBF) [0315381B]; German Center for Diabetes Research; program "Clinician Scientist," University of Tubingen, Medical Faculty
2021-04-13T11:00:22+00:00
sword
importub
filename=package.tar
f7b5b848cb9c5ba3a61a01dd17f23bb1
Willmann, Caroline
false
true
Caroline Willmann
Martin Heni
Katarzyna Linder
Robert Wagner
Norbert Stefan
Jürgen Machann
Matthias Bernd Schulze
Hans-Georg Joost
Hans-Ulrich Haring
Andreas Fritsche
eng
uncontrolled
type 2 diabetes
eng
uncontrolled
prevention
eng
uncontrolled
randomized controlled intervention study
eng
uncontrolled
nutritional factors
eng
uncontrolled
fiber
eng
uncontrolled
red meat
Medizin und Gesundheit
Institut für Ernährungswissenschaft
Referiert
Import
Bronze Open-Access
31661
2009
2009
eng
article
1
--
--
--
From model transformation to incremental bidirectional model synchronization
The model-driven software development paradigm requires that appropriate model transformations are applicable in different stages of the development process. The transformations have to consistently propagate changes between the different involved models and thus ensure a proper model synchronization. However, most approaches today do not fully support the requirements for model synchronization and focus only on classical one-way batch-oriented transformations. In this paper, we present our approach for an incremental model transformation which supports model synchronization. Our approach employs the visual, formal, and bidirectional transformation technique of triple graph grammars. Using this declarative specification formalism, we focus on the efficient execution of the transformation rules and how to achieve an incremental model transformation for synchronization purposes. We present an evaluation of our approach and demonstrate that due to the speedup for the incremental processing in the average case even larger models can be tackled.
http://www.springerlink.com/content/109378
10.1007/s10270-008-0089-9
1619-1366
allegro:1991-2014
10107995
Software and systems modeling. - ISSN 1619-1366. - 8 (2009), 1, S. 21 - 43
Holger Giese
Robert Wagner
Hasso-Plattner-Institut für Digital Engineering gGmbH
Referiert
41767
2018
2018
deu
139
151
article
Universitätsverlag Potsdam
Potsdam
1
--
2018-09-27
--
Schulpraktisches Klavierspiel und inklusives Musizieren im schulischen Kontext
Potsdamer Schriftenreihe zur Musikpädagogik
urn:nbn:de:kobv:517-opus4-417674
online registration
LR 56940 , LR 55400 , DT 1420
CC-BY - Namensnennung 4.0 International
Robert Wagner
Bildung und Erziehung
open_access
Open Access
Universitätsverlag Potsdam
Nicht ermittelbar
PSM 6/2 (2018)
Department Musik und Kunst
Institut für Musik- und Musikpädagogik
Universität Potsdam
Universitätsverlag Potsdam
https://publishup.uni-potsdam.de/files/41767/psm6_2_139-151.pdf
4311
2009
2010
eng
postprint
1
2010-07-19
--
--
GabiPD : the GABI primary database - a plant integrative "omics" database
The GABI Primary Database, GabiPD (http:// www.gabipd.org/), was established in the frame of the German initiative for Genome Analysis of the Plant Biological System (GABI). The goal of GabiPD is to collect, integrate, analyze and visualize primary information from GABI projects. GabiPD constitutes a repository and analysis platform for a wide array of heterogeneous data from high-throughput experiments in several plant species. Data from different ‘omics’ fronts are incorporated (i.e. genomics, transcriptomics, proteomics and metabolomics), originating from 14 different model or crop species. We have developed the concept of GreenCards for textbased retrieval of all data types in GabiPD (e.g. clones, genes, mutant lines). All data types point to a central Gene GreenCard, where gene information is integrated from genome projects or NCBI UniGene sets. The centralized Gene GreenCard allows visualizing ESTs aligned to annotated transcripts as well as displaying identified protein domains and gene structure. Moreover, GabiPD makes available interactive genetic maps from potato and barley, and protein 2DE gels from Arabidopsis thaliana and Brassica napus. Gene expression and metabolic-profiling data can be visualized through MapManWeb. By the integration of complex data in a framework of existing knowledge, GabiPD provides new insights and allows for new interpretations of the data.
urn:nbn:de:kobv:517-opus-45075
4507
Nucleic acids research 37 (2009), Database issue, S. D954 - D959, DOI: 10.1093/nar/gkn611
<hr>The article was originally published by Oxford University Press:<br><a href="http://nar.oxfordjournals.org/">Nucleic Acids Research</a>. - 37 (2009), Database issue, S. D954-D959<br>ISSN 0305-1048<br>DOI <a href="http://dx.doi.org/10.1093/nar/gkn611"> 10.1093/nar/gkn611</a>
Diego Mauricio Riano-Pachon
Axel Nagel
Jost Neigenfind
Robert Wagner
Rico Basekow
Elke Weber
Bernd Müller-Röber
Svenja Diehl
Birgit Kersten
Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
paper 137
eng
uncontrolled
Phosphorylation sites
eng
uncontrolled
Arabidopsis thaliana
eng
uncontrolled
Information
eng
uncontrolled
Proteins
eng
uncontrolled
Families
Biowissenschaften; Biologie
open_access
Institut für Biochemie und Biologie
Universität Potsdam
https://publishup.uni-potsdam.de/files/4311/pmnf137.pdf
41362
2018
2018
deu
218
6/2
book
Universitätsverlag Potsdam
Potsdam
1
2018-09-27
2018-09-27
--
Musikarbeit im Kontext von Inklusion und Integration
Die zweiteilige Publikation „Musikarbeit im Kontext von Inklusion und Integration“ der Potsdamer Schriftenreihe zur Musikpädagogik beinhaltet Erträge aus Veranstaltungen und Qualifikationsarbeiten mehrerer Jahre, die am Lehrstuhl für Musikpädagogik und Musikdidaktik der Universität Potsdam entstanden sind. Beide Bände enthalten neben theoretischen Beiträgen auch Beiträge aus Praxis und Ausbildung in verschiedenen Berufsfeldern, die das besondere Potenzial musikalischer Betätigung für Inklusion und Integration anhand von best-practise-Beispielen darstellen und sind somit als umfassendes Studienmaterial konzipiert.
Der zweite Band erweitert den im ersten Teil auf die Potenziale von Musik für Inklusion gesetzten Schwerpunkt um die Darstellung integrativer und inklusiver Potenziale einzelner ausgewählter musikalischer Aktivitäten und Umgangsweisen mit Musik. Stand im ersten Band die Dokumentation der 2013 am Lehrstuhl für Musikpädagogik und Musikdidaktik durchgeführten internationalen Fachtagung „Musikarbeit im Kontext von Inklusion und Integration“ im Fokus, schließt der zweite Teil mit der Dokumentation eines interdisziplinär und mehrperspektivisch angelegten Projektseminars an, das im Wintersemester 2016/2017 unter der Leitung von Prof. Dr. Birgit Jank durchgeführt wurde. Dieses Seminar setzte neue Impulse für die Entstehung weiterer musikpädagogischer Forschungsarbeiten, aus denen konkrete Handlungsempfehlungen für die Musikarbeit in integrativen und inklusiven Unterrichtssettings abgeleitet werden können.
Potsdamer Schriftenreihe zur Musikpädagogik
Projektberichte und Studienmaterial
978-3-86956-436-4
urn:nbn:de:kobv:517-opus4-413625
2196-5080
1861-8529
online registration
LR 56940 , LR 55400 , DT 1420
<hr/>In Printform erschienen im <a href="http://info.ub.uni-potsdam.de/verlag.htm">Universitätsverlag Potsdam</a>:<br/><br/> Musikarbeit im Kontext von Inklusion und Integration : Projektberichte und Studienmaterial / Anja Bossen, Birgit Jank (Hrsg.). – Potsdam: Universitätsverlag Potsdam, 2018. – 218 S. </br> (Potsdamer Schriftenreihe zur Musikpädagogik ; 6,2)</br> ISSN (print) 1861-8529</br> ISSN (online) 2196-5080</br> ISBN 978-3-86956-436-4 </br> --> <a href="https://shop.verlag.uni-potsdam.de/shop/musikarbeit-im-kontext-von-inklusion-und-integration-2//">bestellen</a>
CC-BY - Namensnennung 4.0 International
Anja Bossen
Alexander Lipp
Birgit Jank
Jan Wysujack
Marc Godau
Frances Haacker
Robert Wagner
Jutta Möhle
Natalija Nikolayeva
Potsdamer Schriftenreihe zur Musikpädagogik
6/2
deu
uncontrolled
Inklusion
deu
uncontrolled
Musik in der Sozialen Arbeit
deu
uncontrolled
Musikunterricht
deu
uncontrolled
Integration
eng
uncontrolled
inclusion
eng
uncontrolled
music in social work
eng
uncontrolled
music education
eng
uncontrolled
integration
Bildung und Erziehung
Musik
open_access
Potsdamer Schriftenreihe zur Musikpädagogik
Universitätsverlag Potsdam
Department Erziehungswissenschaft
Department Lehrerbildung
Universität Potsdam
Universitätsverlag Potsdam
https://publishup.uni-potsdam.de/files/41362/psm6_2.pdf