38748
2015
2015
zho
699
704
6
7
73
article
Science China Press
Beijing
1
--
--
--
Study on the Synthesis of Novel Sugar Amino Acids
新型糖氨基酸类化合物的合成研究
Sugar amino acids (SAAs) are carbohydrate derivatives bearing both amino and carboxylic acid functional groups. SAAs represent an important class of multifunctional building blocks, which are amenable to serve as glycomimetics or peptidomimetics with well-defined structures and useful properties. Because SAAs exist in nature in many forms with various biological activities, recently, many unnatural SAAs, as the demand for finding new molecules to discover new drugs and new materials, have been designed and synthesized by a number of research groups. In this paper, we have developed a convenient method for the synthesis of novel SAAs gluco-7 and galacto-7 for the first time. The structure of gluco-7 was similar to the natural SAA glucosaminuronic acid that was a component of many typical bacterial cell walls and could be used for the preparation of type D flu vaccine; while galacto-7 was similar to the natural SAA galactosaminuronic acid that was one of bacterial Vi-antigen components of Escherichia coli. Starting from unexpensive and commercially available 3,4,6-tri-O-acetyl-D-glucal and 3,4,6-tri-O-acetyl-D-galactal, two novel SAAs gluco-7 and galacto-7 were achieved in the linear 6 steps with 34% overall yield and 19% overall yield, respectively. The key reactions included radical addition, decarboxylation, iodine generation reaction, azide reaction and reductive amination reaction. The crucial step was the synthesis of the target compound gluco-7 from gluco-6. By using method A, the target compound gluco-7 was obtained in 4 steps with 63% overall yield. To optimize the transformation from gluco-6 to gluco-7, method B was developed to generate gluco-7 by using one-pot reaction successfully with 76% yield only in one step. It proved that method B was superior to method A with shorter steps and higher yields. All the new compounds were characterized by IR, H-1 NMR, C-13 NMR and HRMS data. Study on the synthesis and biological evaluation of linear and cyclic oligomers derived from gluco-7 and galacto-7 are currently in progress.
Acta chimica Sinica = Huaxue-xuebao
10.6023/A15030205
0567-7351
wos:2015
WOS:000360199200006
Wang, XB (reprint author), Jiangnan Univ, Sch Biotechnol, Minist Educ, Key Lab Carbohydrate Chem & Biotechnol, Lihu Ave 1800, Wuxi 214122, Jiangsu, Peoples R China., jianyin@jiangnan.edu.cn
National Science Foundation for Young Scientists of China [21302068]; Natural Science Foundation of Jiangsu Province, China [BK20130127]; specialized Research Fund for the Doctoral Program of Higher Education [20120093120002]; Fundamental Research Funds for the Central Universities [JUSRP51319B, JUSRP51411B]
Xuebin Wang
Xiaoli Wang
Jing Hu
Zhaoya Wang
Tukaram M. Pimpalpalle
Torsten Linker
Jian Yin
eng
uncontrolled
sugar amino acids
eng
uncontrolled
glycal
eng
uncontrolled
radical addition
eng
uncontrolled
one-pot reaction
eng
uncontrolled
synthesis
Institut für Chemie
Referiert
8512
2015
2015
deu
143
doctoralthesis
1
--
--
2015-07-07
Zur Optimierung und dem Auslesen molekularer Schalter
quantenchemische Untersuchungen an vier Beispielen
online registration
Manuel Martin Utecht
Chemie und zugeordnete Wissenschaften
Institut für Chemie
Universität Potsdam
Universität Potsdam
7994
2015
eng
4623
4631
3
18
article
Royal Society of Chemistry
Cambridge
1
--
2015-03-17
--
White light emission of IFP-1 by in situ co-doping of the MOF pore system with Eu3+ and Tb3+
Co-doping of the MOF 3∞[Zn(2-methylimidazolate-4-amide-5-imidate)] (IFP-1 = Imidazolate Framework Potsdam-1) with luminescent Eu3+ and Tb3+ ions presents an approach to utilize the porosity of the MOF for the intercalation of luminescence centers and for tuning of the chromaticity to the emission of white light of the quality of a three color emitter. Organic based fluorescence processes of the MOF backbone as well as metal based luminescence of the dopants are combined to one homogenous single source emitter while retaining the MOF's porosity. The lanthanide ions Eu3+ and Tb3+ were doped in situ into IFP-1 upon formation of the MOF by intercalation into the micropores of the growing framework without a structure directing effect. Furthermore, the color point is temperature sensitive, so that a cold white light with a higher blue content is observed at 77 K and a warmer white light at room temperature (RT) due to the reduction of the organic emission at higher temperatures. The study further illustrates the dependence of the amount of luminescent ions on porosity and sorption properties of the MOF and proves the intercalation of luminescence centers into the pore system by low-temperature site selective photoluminescence spectroscopy, SEM and EDX. It also covers an investigation of the border of homogenous uptake within the MOF pores and the formation of secondary phases of lanthanide formates on the surface of the MOF. Crossing the border from a homogenous co-doping to a two-phase composite system can be beneficially used to adjust the character and warmth of the white light. This study also describes two-color emitters of the formula Ln@IFP-1a–d (Ln: Eu, Tb) by doping with just one lanthanide Eu3+ or Tb3+.
Journal of materials chemistry : C, Materials for optical and electronic devices
10.1039/C4TC02919D
2050-7534
2050-7526
online registration
<a href="http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-79953">Zweitveröffentlichung in der Schriftenreihe Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe ; 190</a>
Au-018912
Suvendu Sekhar Mondal
Karsten Behrens
Philipp R. Matthes
Fabian Schönfeld
Jörn Nitsch
Andreas Steffen
Philipp-Alexander Primus
Michael Uwe Kumke
Klaus Müller-Buschbaum
Hans-Jürgen Holdt
Chemie und zugeordnete Wissenschaften
Institut für Chemie
Referiert
Open Access
RSC
Universität Potsdam
39355
2015
2015
eng
4623
4631
9
18
3
article
Royal Society of Chemistry
Cambridge
1
--
--
--
White light emission of IFP-1 by in situ co-doping of the MOF pore system with Eu3+ and Tb3+
Journal of materials chemistry : C, Materials for optical and electronic devices
10.1039/c4tc02919d
2050-7526
2050-7534
wos:2015
WOS:000353768100004
Holdt, HJ (reprint author), Univ Potsdam, Inst Chem, Anorgan Chem, Karl Liebknecht Str 26, D-14476 Golm, Germany., k.mueller-buschbaum@uni-wuerzburg.de; holdt@uni-potsdam.de
Priority Program of the German Research Foundation on "Metal-Organic Frameworks' [1362]; Dr Klaus-Romer foundation
Suvendu Sekhar Mondal
Karsten Behrens
Philipp R. Matthes
Fabian Schönfeld
Jörn Nitsch
Andreas Steffen
Philipp-Alexander Primus
Michael Uwe Kumke
Klaus Müller-Buschbaum
Hans-Jürgen Holdt
Institut für Chemie
Referiert
39234
2015
2015
eng
11
1
91
article
American Physical Society
College Park
1
--
--
--
Weak correlation of starch and volume in synchronized photosynthetic cells
In cultures of unicellular algae, features of single cells, such as cellular volume and starch content, are thought to be the result of carefully balanced growth and division processes. Single-cell analyses of synchronized photoautotrophic cultures of the unicellular alga Chlamydomonas reinhardtii reveal, however, that the cellular volume and starch content are only weakly correlated. Likewise, other cell parameters, e.g., the chlorophyll content per cell, are only weakly correlated with cell size. We derive the cell size distributions at the beginning of each synchronization cycle considering growth, timing of cell division and daughter cell release, and the uneven division of cell volume. Furthermore, we investigate the link between cell volume growth and starch accumulation. This work presents evidence that, under the experimental conditions of light-dark synchronized cultures, the weak correlation between both cell features is a result of a cumulative process rather than due to asymmetric partition of biomolecules during cell division. This cumulative process necessarily limits cellular similarities within a synchronized cell population.
Physical review : E, Statistical, nonlinear and soft matter physics
10.1103/PhysRevE.91.012711
25679646
1539-3755
1550-2376
wos:2015
012711
WOS:000349868500006
Rading, MM (reprint author), Max Planck Inst Colloids & Interfaces, Dept Theory & Biosyst, D-14476 Potsdam, Germany., rading@uni-potsdam.de; angelo.valleriani@mpikg.mpg.de
German Federal Ministry of Education and Research within the program
Unternehmen Region [03Z2AN12]; GoFORSYS [0313924]
M. Michael Rading
Michael Sandmann
Martin Steup
Davide Chiarugi
Angelo Valleriani
Institut für Chemie
Referiert
39334
2015
2015
eng
19656
19669
14
29
17
article
Royal Society of Chemistry
Cambridge
1
--
--
--
Vibrationally resolved optical spectra of modified diamondoids obtained from time-dependent correlation function methods
Optical properties of modified diamondoids have been studied theoretically using vibrationally resolved electronic absorption, emission and resonance Raman spectra. A time-dependent correlation function approach has been used for electronic two-state models, comprising a ground state (g) and a bright, excited state (e), the latter determined from linear-response, time-dependent density functional theory (TD-DFT). The harmonic and Condon approximations were adopted. In most cases origin shifts, frequency alteration and Duschinsky rotation in excited states were considered. For other cases where no excited state geometry optimization and normal mode analysis were possible or desired, a short-time approximation was used. The optical properties and spectra have been computed for (i) a set of recently synthesized sp(2)/sp(3) hybrid species with CQC double-bond connected saturated diamondoid subunits, (ii) functionalized (mostly by thiol or thione groups) diamondoids and (iii) urotropine and other C-substituted diamondoids. The ultimate goal is to tailor optical and electronic features of diamondoids by electronic blending, functionalization and substitution, based on a molecular-level understanding of the ongoing photophysics.
Physical chemistry, chemical physics : a journal of European Chemical Societies
10.1039/c5cp02615f
26151912
1463-9076
1463-9084
wos:2015
WOS:000358207400083
Saalfrank, P (reprint author), Univ Potsdam, Inst Chem, Karl Liebknecht Str 24-25, D-14476 Potsdam, Germany., peter.saalfrank@uni-potsdam.de
DFG [Sa 547/11-1]
Shiladitya Banerjee
Tony Stueker
Peter Saalfrank
Institut für Chemie
Referiert
8682
2015
eng
postprint
1
--
--
--
Vibrationally resolved optical spectra of modified diamondoids obtained from time-dependent correlation function methods
Optical properties of modified diamondoids have been studied theoretically using vibrationally resolved electronic absorption, emission and resonance Raman spectra. A time-dependent correlation function approach has been used for electronic two-state models, comprising a ground state (g) and a bright, excited state (e), the latter determined from linear-response, time-dependent density functional theory (TD-DFT). The harmonic and Condon approximations were adopted. In most cases origin shifts, frequency alteration and Duschinsky rotation in excited states were considered. For other cases where no excited state geometry optimization and normal mode analysis were possible or desired, a short-time approximation was used. The optical properties and spectra have been computed for (i) a set of recently synthesized sp2/sp3 hybrid species with C[double bond, length as m-dash]C double-bond connected saturated diamondoid subunits, (ii) functionalized (mostly by thiol or thione groups) diamondoids and (iii) urotropine and other C-substituted diamondoids. The ultimate goal is to tailor optical and electronic features of diamondoids by electronic blending, functionalization and substitution, based on a molecular-level understanding of the ongoing photophysics.
urn:nbn:de:kobv:517-opus4-86826
online registration
https://www.uni-potsdam.de/verlagsarchivweb/html/8682/html/pubs.rsc.org/en/content/articlehtml/2015/cp/c5cp02615f.html
<a href="http://publishup.uni-potsdam.de/opus4-ubp/frontdoor/index/index/docId/8681">Bibliographieeintrag der Originalveröffentlichung/Quelle</a>
Shiladitya Banerjee
Tony Stüker
Peter Saalfrank
Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
211
Chemie und zugeordnete Wissenschaften
open_access
Institut für Chemie
Referiert
Universität Potsdam
https://publishup.uni-potsdam.de/files/8682/pmnr211.pdf
8681
2015
eng
19656
19669
29
17
article
Royal Society of Chemistry
Cambridge
1
--
2015-07-01
--
Vibrationally resolved optical spectra of modified diamondoids obtained from time-dependent correlation function methods
Optical properties of modified diamondoids have been studied theoretically using vibrationally resolved electronic absorption, emission and resonance Raman spectra. A time-dependent correlation function approach has been used for electronic two-state models, comprising a ground state (g) and a bright, excited state (e), the latter determined from linear-response, time-dependent density functional theory (TD-DFT). The harmonic and Condon approximations were adopted. In most cases origin shifts, frequency alteration and Duschinsky rotation in excited states were considered. For other cases where no excited state geometry optimization and normal mode analysis were possible or desired, a short-time approximation was used. The optical properties and spectra have been computed for (i) a set of recently synthesized sp2/sp3 hybrid species with C[double bond, length as m-dash]C double-bond connected saturated diamondoid subunits, (ii) functionalized (mostly by thiol or thione groups) diamondoids and (iii) urotropine and other C-substituted diamondoids. The ultimate goal is to tailor optical and electronic features of diamondoids by electronic blending, functionalization and substitution, based on a molecular-level understanding of the ongoing photophysics.
Physical chemistry, chemical physics : PCCP ; a journal of European chemical societies
10.1039/C5CP02615F
1463-9084
1463-9076
Au-018918
online registration
<a href="http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-86826">Zweitveröffentlichung in der Schriftenreihe Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe ; 211</a>
Shiladitya Banerjee
Tony Stüker
Peter Saalfrank
Chemie und zugeordnete Wissenschaften
Institut für Chemie
Referiert
Open Access
RSC
38441
2015
2015
eng
4589
4593
5
22
6
article
American Chemical Society
Washington
1
--
--
--
Using DNA origami nanostructures to determine absolute cross sections for UV photon-induced DNA strand breakage
We have characterized ultraviolet (UV) photon-induced DNA strand break processes by determination of absolute cross sections for photoabsorption and for sequence-specific DNA single strand breakage induced by photons in an energy range from 6.50 to 8.94 eV. These represent the lowest-energy photons able to induce DNA strand breaks. Oligonudeotide targets are immobilized on a UV transparent substrate in controlled quantities through attachment to DNA origami templates. Photon-induced dissociation of single DNA strands is visualized and quantified using atomic force microscopy. The obtained quantum yields for strand breakage vary between 0.06 and 0.5, indicating highly efficient DNA strand breakage by UV photons, which is clearly dependent on the photon energy. Above the ionization threshold strand breakage becomes clearly the dominant form of DNA radiation damage, which is then also dependent on the nucleotide sequence.
The journal of physical chemistry letters
10.1021/acs.jpclett.5b02238
26536162
1948-7185
wos:2015
WOS:000365460700022
Bald, I (reprint author), Univ Potsdam, Inst Chem, Karl Liebknecht Str 24-25, D-14469 Potsdam, Germany., bald@uni-potsdam.de
Marie Curie FP7 Integration Grant within the seventh European Union
Framework Programme; Deutsche Forschungsgemeinschaft (DFG); synchrotron
SOLEIL [20131271]; German Academic Exchange Service (DAAD) - German
Federal Ministry of Education and Research [57055766]; MESTD of RS
[171020]; COST Action [MP1002]
Stefanie Vogel
Jenny Rackwitz
Robin Schuerman
Julia Prinz
Aleksandar R. Milosavljevic
Matthieu Refregiers
Alexandre Giuliani
Ilko Bald
Institut für Chemie
Referiert
8969
2015
2016
eng
5476
5483
postprint
1
--
2016-02-10
--
Use of a 4,5-dicyanoimidazolate anion based ionic liquid for the synthesis of iron and silver nanoparticles
Sixteen new ionic liquids (ILs) with tetraethylammonium, 1-butyl-3-methylimidazolium, 3-methyl-1-octylimidazolium and tetrabutylphosphonium cations paired with 2-substituted 4,5-dicyanoimidazolate anions (substituent at C2 = methyl, trifluoromethyl, pentafluoroethyl, N,N′-dimethyl amino and nitro) have been synthesized and characterized by using differential scanning calorimetry (DSC), thermogravimetric analysis (TGA). The effects of cation and anion type and structure of the resulting ILs, including several room temperature ionic liquids (RTILs), are reflected in the crystallization, melting points and thermal decomposition of the ILs. ILs exhibited large liquid and crystallization ranges and formed glasses on cooling with glass transition temperatures in the range of −22 to −71 °C. We selected one of the newly designed ILs due to its bigger size, compared to the common conventional IL anion and high electron-withdrawing nitrile group leads to an overall stabilization anion that may stabilize the metal nanoparticles. Stable and better separated iron and silver nanoparticles are obtained by the decomposition of corresponding Fe2(CO)9 and AgPF6, respectively, under N2-atmosphere in newly designed nitrile functionalized 4,5-dicyanoimidazolate anion based IL. Very small and uniform size for Fe-nanoparticles of about 1.8 ± 0.6 nm were achieved without any additional stabilizers or capping molecules. Comparatively bigger size of Ag-nanoparticles was obtained through the reduction of AgPF6 by hydrogen gas. Additionally, the AgPF6 precursor was decomposed under microwave irradiation (MWI), fabricating nut-in-shell-like, that is, core-separated-from-shell Ag-nano-structures.
urn:nbn:de:kobv:517-opus4-89696
online registration
Au-032774
<a href="http://publishup.uni-potsdam.de/opus4-ubp/frontdoor/index/index/docId/8968">Bibliographieeintrag der Originalveröffentlichung/Quelle</a>
Dalton Trans. (2016) Nr.45, S. 5476-5483. DOI: 10.1039/C6DT00225K
Suvendu Sekhar Mondal
Dorothea Marquardt
Christoph Janiak
Hans-Jürgen Holdt
Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
220
Chemie und zugeordnete Wissenschaften
open_access
Institut für Chemie
Referiert
Open Access
Universität Potsdam
https://publishup.uni-potsdam.de/files/8969/pmnr220.pdf