9924
2016
2016
eng
113
doctoralthesis
1
--
--
--
Gene evolution and expression patterns in the all-female fish Amazon molly: Poecilia formosa
online registration
Potsdam, Univ., Diss., 2016
Fangjun Zhu
Biowissenschaften; Biologie
Institut für Biochemie und Biologie
Universität Potsdam
Universität Potsdam
9854
2016
eng
175
doctoralthesis
1
--
--
--
Investigation of the TCA cycle and glycolytic metabolons and their physiological impacts in plants
online registration
Potsdam, Univ., Diss., 2016
Youjun Zhang
Biowissenschaften; Biologie
Institut für Biochemie und Biologie
Universität Potsdam
Universität Potsdam
39750
2016
2016
eng
108
doctoralthesis
1
--
--
--
Functional characterization of two MYB transcription factors, MYB95 and MYB47, in Arabidopsis thaliana
online registration
Dissertation, Universität Potsdam, 2016
Keine öffentliche Lizenz: Unter Urheberrechtsschutz
Ke Xu
Pflanzen (Botanik)
Institut für Biochemie und Biologie
Universität Potsdam
Universität Potsdam
10075
2016
2016
2016
eng
x, 84
doctoralthesis
1
--
--
2016-04-11
Tracing Changes in Space and Time
The horse is a fascinating animal symbolizing power, beauty, strength and grace. Among all the animal species domesticated the horse had the largest impact on the course of human history due to its importance for warfare and transportation. Studying the process of horse domestication contributes to the knowledge about the history of horses and even of our own species.
Research based on molecular methods has increasingly focused on the genetic basis of horse domestication. Mitochondrial DNA (mtDNA) analyses of modern and ancient horses detected immense maternal diversity, probably due to many mares that contributed to the domestic population. However, mtDNA does not provide an informative phylogeographic structure. In contrast, Y chromosome analyses displayed almost complete uniformity in modern stallions but relatively high diversity in a few ancient horses. Further molecular markers that seem to be well suited to infer the domestication history of horses or genetic and phenotypic changes during this process are loci associated with phenotypic traits.
This doctoral thesis consists of three different parts for which I analyzed various single nucleotide polymorphisms (SNPs) associated with coat color, locomotion or Y chromosomal variation of horses. These SNPs were genotyped in 350 ancient horses from the Chalcolithic (5,000 BC) to the Middle Ages (11th century). The distribution of the samples ranges from China to the Iberian Peninsula and Iceland. By applying multiplexed next-generation sequencing (NGS) I sequenced short amplicons covering the relevant positions: i) eight coat-color-associated mutations in six genes to deduce the coat color phenotype; ii) the so-called ’Gait-keeper’ SNP in the DMRT3 gene to screen for the ability to amble; iii) 16 SNPs previously detected in ancient horses to infer the corresponding haplotype. Based on these data I investigated the occurrence and frequencies of alleles underlying the respective phenotypes as well as Y chromosome haplotypes at different times and regions. Also, selection coefficients for several Y chromosome lineages or phenotypes were estimated.
Concerning coat color differences in ancient horses my work constitutes the most comprehensive study to date. I detected an increase of chestnut horses in the Middle Ages as well as differential selection for spotted and solid phenotypes over time which reflects changing human preferences.
With regard to ambling horses, the corresponding allele was present in medieval English and Icelandic horses. Based on these results I argue that Norse settlers, who frequently invaded parts of Britain, brought ambling individuals to Iceland from the British Isles which can be regarded the origin of this trait. Moreover, these settlers appear to have selected for ambling in Icelandic horses.
Relating to the third trait, the paternal diversity, these findings represent the largest ancient dataset of Y chromosome variation in non-humans. I proved the existence of several Y chromosome haplotypes in early domestic horses. The decline of Y chromosome variation coincides with the movement of nomadic peoples from the Eurasian steppes and later with different breeding practices in the Roman period.
In conclusion, positive selection was estimated for several phenotypes/lineages
in different regions or times which indicates that these were preferred by humans. Furthermore, I could successfully infer the distribution and dispersal of horses in association with human movements and actions. Thereby, a better understanding of the influence of people on the changing appearance and genetic diversity of domestic horses could be gained. My results also emphasize the close relationship of ancient genetics and archeology or history and that only in combination well-founded conclusions can be reached.
Paternal Diversity and Phenotypic Traits during Horse Domestication
online registration
Potsdam, Univ., Diss., 2016
Saskia Wutke
eng
uncontrolled
ancient DNA
eng
uncontrolled
domestication
eng
uncontrolled
horse
eng
uncontrolled
equus caballus
eng
uncontrolled
locomotion
eng
uncontrolled
Y chromosome
eng
uncontrolled
coat colour
Biowissenschaften; Biologie
Tiere (Zoologie)
Geschichte des Altertums bis ca. 499, Archäologie
Institut für Biochemie und Biologie
Universität Potsdam
Universität Potsdam
39624
2016
eng
176
doctoralthesis
1
--
--
--
Mid- to Late Holocene environmental dynamics on the Yukon Coastal Plain and Herschel Island (Canada) - envidence from polygonal peatlands and lake sediment
online registration
Dissertation, Universität Potsdam, 2016
Keine öffentliche Lizenz: Unter Urheberrechtsschutz
Juliane Wolter
Fossilien, Paläontologie
Institut für Geowissenschaften
Institut für Erd- und Umweltwissenschaften
Universität Potsdam
Universität Potsdam
41834
2016
2019
2016
eng
xii, 232
doctoralthesis
Routledge
New York
1
--
--
2016-12-13
Drug Control and International Law
This book provides for an extensive legal analysis of the international drug control system in light of the growing challenges and criticism that this system faces. In the current debate on global drug policy, the central pillars of the international drug control system – the UN Drug Conventions as well as its institutions – are portrayed as outdated, suppressive and seen as an obstacle to necessary changes. The book’s objective is to provide an in-depth and positivist insight into drug control’s present legal framework and thus provide for a better understanding of the normative assumptions upon which drug control is currently based. This is attained by clarifying the objectives of the international drug control system and the premises by which these objectives are to be achieved.
The objective of the current global framework of international drug control is the limitation of drugs to medical and scientific purposes. The meaning of this objective and its concrete implications for States’ parties as well as its problems from the perspective of other regimes of international law, most notably international human rights law, are extensively analysed. Additionally, the book focuses on how the international drug control system attempts to reach the objective of confining drugs to medical and scientific purposes, i.e. by setting up a universal system that exercises a rigid control on drug supply. The consequences of this heavy focus on the reduction of drug supply are outlined, and the book concludes by making suggestions on how the international drug control system could be reformed in the near future in order to better meet the existing challenges.
The analysis occurs from a general international law perspective. It aims to map the international drug control system within a wider context of international law and to understand whether the problems that the international drug control system faces are exemplary for the difficulties that institutionalized systems of global scope face in the twenty-first century.
Routledge Research in International Law
978-1-138-48604-1
online registration
Keine öffentliche Lizenz: Unter Urheberrechtsschutz
Daniel Wisehart
Recht
Öffentliches Recht
Universität Potsdam
Universität Potsdam
10104
2016
2016
2016
eng
279
doctoralthesis
1
--
--
2016-12-01
Climate change impacts in an increasingly connected world
online registration
Potsdam, Univ., Diss., 2016
Leonie Wenz
Physik
Institut für Physik und Astronomie
Universität Potsdam
Universität Potsdam
39481
2016
2016
eng
122
doctoralthesis
1
--
--
--
On the role of monomer drops and swelling in aqueous heterophase polymerization
online registration
Dissertation, Universität Potsdam, 2016
Chunxiang Wei
Chemie und zugeordnete Wissenschaften
Institut für Chemie
Universität Potsdam
Universität Potsdam
39753
2016
2016
2017
eng
142
doctoralthesis
1
--
--
2017-05-29
Deep Learning of Multimodal Representations
online registration
Dissertation, Universität Potsdam, 2016
Keine öffentliche Lizenz: Unter Urheberrechtsschutz
Cheng Wang
Datenverarbeitung; Informatik
Hasso-Plattner-Institut für Digital Engineering gGmbH
Universität Potsdam
Universität Potsdam
10067
2016
eng
115
doctoralthesis
1
--
--
--
The changing role of snowmelt- and rainfall dominated floods in Norway under climate change
observations, projections, uncertainties
online registration
Potsdam, Univ., Diss., 2016
Klaus Josef Vormoor
Naturwissenschaften und Mathematik
Institut für Geowissenschaften
Institut für Erd- und Umweltwissenschaften
Universität Potsdam
Universität Potsdam