Dokument-ID Dokumenttyp Verfasser/Autoren Herausgeber Haupttitel Abstract Auflage Verlagsort Verlag Erscheinungsjahr Seitenzahl Schriftenreihe Titel Schriftenreihe Bandzahl ISBN Quelle der Hochschulschrift Konferenzname Quelle:Titel Quelle:Jahrgang Quelle:Heftnummer Quelle:Erste Seite Quelle:Letzte Seite URN DOI Abteilungen OPUS4-55000 misc Kämpf, Lucas; Plessen, Birgit; Lauterbach, Stefan; Nantke, Carla; Meyer, Hanno; Chapligin, Bernhard; Brauer, Achim Stable oxygen and carbon isotopes of carbonates in lake sediments as a paleoflood proxy Lake sediments are increasingly explored as reliable paleoflood archives. In addition to established flood proxies including detrital layer thickness, chemical composition, and grain size, we explore stable oxygen and carbon isotope data as paleoflood proxies for lakes in catchments with carbonate bedrock geology. In a case study from Lake Mondsee (Austria), we integrate high-resolution sediment trapping at a proximal and a distal location and stable isotope analyses of varved lake sediments to investigate flood-triggered detrital sediment flux. First, we demonstrate a relation between runoff, detrital sediment flux, and isotope values in the sediment trap record covering the period 2011-2013 CE including 22 events with daily (hourly) peak runoff ranging from 10 (24) m(3) s(-1) to 79 (110) m(3) s(-1). The three- to ten-fold lower flood-triggered detrital sediment deposition in the distal trap is well reflected by attenuated peaks in the stable isotope values of trapped sediments. Next, we show that all nine flood-triggered detrital layers deposited in a sediment record from 1988 to 2013 have elevated isotope values compared with endogenic calcite. In addition, even two runoff events that did not cause the deposition of visible detrital layers are distinguished by higher isotope values. Empirical thresholds in the isotope data allow estimation of magnitudes of the majority of floods, although in some cases flood magnitudes are overestimated because local effects can result in too-high isotope values. Hence we present a proof of concept for stable isotopes as reliable tool for reconstructing flood frequency and, although with some limitations, even for flood magnitudes. 2019 7 Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe 1 urn:nbn:de:kobv:517-opus4-550004 10.25932/publishup-55000 Institut für Geowissenschaften OPUS4-54993 misc Schorn, Sina; Salman-Carvalho, Verena; Littmann, Sten; Ionescu, Danny; Grossart, Hans-Peter; Cypionka, Heribert Cell architecture of the giant sulfur bacterium achromatium oxaliferum Achromatium oxaliferum is a large sulfur bacterium easily recognized by large intracellular calcium carbonate bodies. Although these bodies often fill major parts of the cells' volume, their role and specific intracellular location are unclear. In this study, we used various microscopy and staining techniques to identify the cell compartment harboring the calcium carbonate bodies. We observed that Achromatium cells often lost their calcium carbonate bodies, either naturally or induced by treatments with diluted acids, ethanol, sodium bicarbonate and UV radiation which did not visibly affect the overall shape and motility of the cells (except for UV radiation). The water-soluble fluorescent dye fluorescein easily diffused into empty cavities remaining after calcium carbonate loss. Membranes (stained with Nile Red) formed a network stretching throughout the cell and surrounding empty or filled calcium carbonate cavities. The cytoplasm (stained with FITC and SYBR Green for nucleic acids) appeared highly condensed and showed spots of dissolved Ca2+ (stained with Fura-2). From our observations, we conclude that the calcium carbonate bodies are located in the periplasm, in extra-cytoplasmic pockets of the cytoplasmic membrane and are thus kept separate from the cell's cytoplasm. This periplasmic localization of the carbonate bodies might explain their dynamic formation and release upon environmental changes. 2019 10 Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe 2 urn:nbn:de:kobv:517-opus4-549935 10.25932/publishup-54993 Institut für Biochemie und Biologie OPUS4-60815 Wissenschaftlicher Artikel Schorn, Sina; Salman-Carvalho, Verena; Littmann, Sten; Ionescu, Danny; Grossart, Hans-Peter; Cypionka, Heribert Cell architecture of the giant sulfur bacterium achromatium oxaliferum Achromatium oxaliferum is a large sulfur bacterium easily recognized by large intracellular calcium carbonate bodies. Although these bodies often fill major parts of the cells' volume, their role and specific intracellular location are unclear. In this study, we used various microscopy and staining techniques to identify the cell compartment harboring the calcium carbonate bodies. We observed that Achromatium cells often lost their calcium carbonate bodies, either naturally or induced by treatments with diluted acids, ethanol, sodium bicarbonate and UV radiation which did not visibly affect the overall shape and motility of the cells (except for UV radiation). The water-soluble fluorescent dye fluorescein easily diffused into empty cavities remaining after calcium carbonate loss. Membranes (stained with Nile Red) formed a network stretching throughout the cell and surrounding empty or filled calcium carbonate cavities. The cytoplasm (stained with FITC and SYBR Green for nucleic acids) appeared highly condensed and showed spots of dissolved Ca2+ (stained with Fura-2). From our observations, we conclude that the calcium carbonate bodies are located in the periplasm, in extra-cytoplasmic pockets of the cytoplasmic membrane and are thus kept separate from the cell's cytoplasm. This periplasmic localization of the carbonate bodies might explain their dynamic formation and release upon environmental changes. Oxford Oxford University Press 2019 8 FEMS Microbiology Ecology 96 2 1 8 10.1093/femsec/fiz200 Institut für Biochemie und Biologie OPUS4-60836 Wissenschaftlicher Artikel Kämpf, Lucas; Plessen, Birgit; Lauterbach, Stefan; Nantke, Carla; Meyer, Hanno; Chapligin, Bernhard; Brauer, Achim Stable oxygen and carbon isotopes of carbonates in lake sediments as a paleoflood proxy Lake sediments are increasingly explored as reliable paleoflood archives. In addition to established flood proxies including detrital layer thickness, chemical composition, and grain size, we explore stable oxygen and carbon isotope data as paleoflood proxies for lakes in catchments with carbonate bedrock geology. In a case study from Lake Mondsee (Austria), we integrate high-resolution sediment trapping at a proximal and a distal location and stable isotope analyses of varved lake sediments to investigate flood-triggered detrital sediment flux. First, we demonstrate a relation between runoff, detrital sediment flux, and isotope values in the sediment trap record covering the period 2011-2013 CE including 22 events with daily (hourly) peak runoff ranging from 10 (24) m(3) s(-1) to 79 (110) m(3) s(-1). The three- to ten-fold lower flood-triggered detrital sediment deposition in the distal trap is well reflected by attenuated peaks in the stable isotope values of trapped sediments. Next, we show that all nine flood-triggered detrital layers deposited in a sediment record from 1988 to 2013 have elevated isotope values compared with endogenic calcite. In addition, even two runoff events that did not cause the deposition of visible detrital layers are distinguished by higher isotope values. Empirical thresholds in the isotope data allow estimation of magnitudes of the majority of floods, although in some cases flood magnitudes are overestimated because local effects can result in too-high isotope values. Hence we present a proof of concept for stable isotopes as reliable tool for reconstructing flood frequency and, although with some limitations, even for flood magnitudes. Melville, NY American Institute of Physics 2019 5 Geology / the Geological Society of America 48 1 3 7 10.1130/G46593.1 Institut für Geowissenschaften OPUS4-61354 Wissenschaftlicher Artikel Harms, Laura M.; Scalbert, Augustin; Zamora-Ros, Raul; Rinaldi, Sabina; Jenab, Mazda; Murphy, Neil; Achaintre, David; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Aleksandrova, Krasimira Plasma polyphenols associated with lower high-sensitivity C-reactive protein concentrations Experimental studies have reported on the anti-inflammatory properties of polyphenols. However, results from epidemiological investigations have been inconsistent and especially studies using biomarkers for assessment of polyphenol intake have been scant. We aimed to characterise the association between plasma concentrations of thirty-five polyphenol compounds and low-grade systemic inflammation state as measured by high-sensitivity C-reactive protein (hsCRP). A cross-sectional data analysis was performed based on 315 participants in the European Prospective Investigation into Cancer and Nutrition cohort with available measurements of plasma polyphenols and hsCRP. In logistic regression analysis, the OR and 95 % CI of elevated serum hsCRP (>3 mg/l) were calculated within quartiles and per standard deviation higher level of plasma polyphenol concentrations. In a multivariable-adjusted model, the sum of plasma concentrations of all polyphenols measured (per standard deviation) was associated with 29 (95 % CI 50, 1) % lower odds of elevated hsCRP. In the class of flavonoids, daidzein was inversely associated with elevated hsCRP (OR 0 center dot 66, 95 % CI 0 center dot 46, 0 center dot 96). Among phenolic acids, statistically significant associations were observed for 3,5-dihydroxyphenylpropionic acid (OR 0 center dot 58, 95 % CI 0 center dot 39, 0 center dot 86), 3,4-dihydroxyphenylpropionic acid (OR 0 center dot 63, 95 % CI 0 center dot 46, 0 center dot 87), ferulic acid (OR 0 center dot 65, 95 % CI 0 center dot 44, 0 center dot 96) and caffeic acid (OR 0 center dot 69, 95 % CI 0 center dot 51, 0 center dot 93). The odds of elevated hsCRP were significantly reduced for hydroxytyrosol (OR 0 center dot 67, 95 % CI 0 center dot 48, 0 center dot 93). The present study showed that polyphenol biomarkers are associated with lower odds of elevated hsCRP. Whether diet rich in bioactive polyphenol compounds could be an effective strategy to prevent or modulate deleterious health effects of inflammation should be addressed by further well-powered longitudinal studies. Cambridge Cambridge University Press 2019 11 British Journal of Nutrition 123 2 198 208 10.1017/S0007114519002538 Institut für Ernährungswissenschaft OPUS4-62899 Konferenzveröffentlichung Grum, Marcus; Rapp, Simon; Gronau, Norbert; Albers, Albert Shishkov, Boris Accelerating knowledge As knowledge-intensive processes are often carried out in teams and demand for knowledge transfers among various knowledge carriers, any optimization in regard to the acceleration of knowledge transfers obtains a great economic potential. Exemplified with product development projects, knowledge transfers focus on knowledge acquired in former situations and product generations. An adjustment in the manifestation of knowledge transfers in its concrete situation, here called intervention, therefore can directly be connected to the adequate speed optimization of knowledge-intensive process steps. This contribution presents the specification of seven concrete interventions following an intervention template. Further, it describes the design and results of a workshop with experts as a descriptive study. The workshop was used to assess the practical relevance of interventions designed as well as the identification of practical success factors and barriers of their implementation. Cham Springer 2019 19 Business modeling and software design 356 978-3-030-24853-6 95 113 10.1007/978-3-030-24854-3_7 Fachgruppe Betriebswirtschaftslehre OPUS4-62698 Wissenschaftlicher Artikel Balderjahn, Ingo; Lee, Michael S. W.; Seegebarth, Barbara; Peyer, Mathias A sustainable pathway to consumer wellbeing This study investigates the effect of different anticonsumption constructs on consumer wellbeing. The study assumes that people will only lower their level of consumption if doing so does not also lower personal wellbeing. More precisely, this research investigates how specific subtypes of sustainable anticonsumption (e.g., voluntary simplicity, collaborative consumption, and debt-free living) relate to different states of consumer's wellbeing (e.g., financial, psychosocial, and subjective wellbeing). This work also examines whether consumer empowerment can improve personal wellbeing and strengthen the anticonsumption wellbeing relationship. The results show that voluntarily foregoing consumption does not reduce wellbeing and consumer empowerment plays a significant role in supporting sustainable pathways to consumer wellbeing. This study reasons that empowerment improves consumer sovereignty, but may be detrimental for consumers heavily concerned about debt-free living. The present investigation concludes by proposing implications for public and consumer policymakers wishing to promote appropriate sustainable (anticonsumption) pathways to consumer wellbeing. Malden, Mass. Wiley 2019 33 The Journal of consumer affairs 54 2 456 488 10.1111/joca.12278 Wirtschaftswissenschaften OPUS4-62547 Review Lampart, Fabian Rezension zu: Agethen, Matthias: Vergemeinschaftung, Modernisierung, Verausgabung : Nationalökonomie und Erzählliteratur in der zweiten Hälfte des 19. Jahrhunderts. - Göttingen: V & R unipress, 2018. - (Literatur- und Mediengeschichte der Moderne ; 5). - Zugl.: Diss., Münster, 2017. - ISBN: 978-3-8471-0788-0 Berlin, Boston de Gruyter 2019 7 Scientia poetica : Jahrbuch für Geschichte der Literatur und der Wissenschaften 23 1 358 364 10.1515/scipo-2019-030 Institut für Germanistik OPUS4-62383 Wissenschaftlicher Artikel Wiebke, Ullmann Warum hat Bayern mehr Feldhasen als Brandenburg? Braunschweig oerding print GmbH 2019 2 Vielfalt in der Uckermark : Forschungsprojekte 2015 - 2018 46 47 Institut für Biochemie und Biologie OPUS4-62385 Wissenschaftlicher Artikel Teckentrup, Lisa Gefahr an jeder Ecke Braunschweig oerding print GmbH 2019 2 Vielfalt in der Uckermark : Forschungsprojekte 2015 - 2018 54 55 Institut für Biochemie und Biologie OPUS4-62384 Wissenschaftlicher Artikel Schäfer, Merlin Mut macht einsam Braunschweig oerding print GmbH 2019 2 Vielfalt in der Uckermark : Forschungsprojekte 2015 - 2018 52 53 Institut für Biochemie und Biologie OPUS4-62382 Wissenschaftlicher Artikel Kowalski, Gabriele Joanna Auf dem Sprung Braunschweig oerding print GmbH 2019 2 Vielfalt in der Uckermark : Forschungsprojekte 2015 - 2018 41 42 Institut für Biochemie und Biologie OPUS4-62381 Wissenschaftlicher Artikel Raatz, Larissa Wirtschaften in einer reich strukturierten Landschaft - geht das ? Braunschweig oerding print GmbH 2019 2 Vielfalt in der Uckermark : Forschungsprojekte 2015 - 2018 32 33 Institut für Biochemie und Biologie OPUS4-62380 Wissenschaftlicher Artikel Lozada Gobilard, Sissi Donna Können auch Pflanzen zwischen den Söllen "wandern" Braunschweig oerding print GmbH 2019 2 Vielfalt in der Uckermark : Forschungsprojekte 2015 - 2018 30 31 Institut für Biochemie und Biologie OPUS4-62379 Wissenschaftlicher Artikel Litwin, Magdalena; Colangeli, Pierluigi Wie und wohin reisen Wasserflöhe? Braunschweig oerding print GmbH 2019 2 Vielfalt in der Uckermark : Forschungsprojekte 2015 - 2018 28 29 Institut für Biochemie und Biologie OPUS4-62378 Wissenschaftlicher Artikel Maaß, Stefanie Blick in die Zukunft Braunschweig oerding print GmbH 2019 2 Vielfalt in der Uckermark : Forschungsprojekte 2015 - 2018 24 25 Institut für Biochemie und Biologie OPUS4-62377 Wissenschaftlicher Artikel Weiß, Lina; Wulff, Monika Veränderung der Landnutzung in der nord-westlichen Uckermark von 1780 bis heute Braunschweig oerding print GmbH 2019 2 Vielfalt in der Uckermark : Forschungsprojekte 2015 - 2018 20 21 Institut für Biochemie und Biologie OPUS4-62367 Buch (Monographie) Berlin-Brandenburgisches Institut für Biodiverstätsforschung, Vielfalt in der Uckermark Braunschweig oerding print GmbH 2019 62 Institut für Biochemie und Biologie OPUS4-61076 Wissenschaftlicher Artikel Gu, Sasa; Risse, Sebastian; Lu, Yan; Ballauff, Matthias Mechanism of the oxidation of 3,3′,5,5′-tetramethylbenzidine catalyzed by peroxidase-like Pt nanoparticles immobilized in spherical polyelectrolyte brushes Experimental and kinetic modelling studies are presented to investigate the mechanism of 3,3 ',5,5 '-tetramethylbenzidine (TMB) oxidation by hydrogen peroxide (H2O2) catalyzed by peroxidase-like Pt nanoparticles immobilized in spherical polyelectrolyte brushes (SPB-Pt). Due to the high stability of SPB-Pt colloidal, this reaction can be monitored precisely in situ by UV/VIS spectroscopy. The time-dependent concentration of the blue-colored oxidation product of TMB expressed by different kinetic models was used to simulate the experimental data by a genetic fitting algorithm. After falsifying the models with abundant experimental data, it is found that both H2O2 and TMB adsorb on the surface of Pt nanoparticles to react, indicating that the reaction follows the Langmuir-Hinshelwood mechanism. A true rate constant k, characterizing the rate-determining step of the reaction and which is independent on the amount of catalysts used, is obtained for the first time. Furthermore, it is found that the product adsorbes strongly on the surface of nanoparticles, thus inhibiting the reaction. The entire analysis provides a new perspective to study the catalytic mechanism and evaluate the catalytic activity of the peroxidase-like nanoparticles. Weinheim Wiley-VCH 2019 9 ChemPhysChem 21 5 450 458 10.1002/cphc.201901087 Institut für Chemie OPUS4-60907 Wissenschaftlicher Artikel Kiefer, Thomas; Krahl, Dorothea; Hirt, Carsten; Völler, Heinz; Voelkel, Lorenz; Daeschlein, Georg Influence of treatment caused impairments on anxiety and depression in patients with cancer of the Esophagus or the Esophagogastric junction Purpose After therapy of cancer of the esophagus or the esophagogastric junction, patients often suffer from anxiety and depression. Some risk factors for elevated anxiety and depression are reported, but the influence of steatorrhea, the frequency of which has only recently been reported, has not yet been investigated. Method Using the Hospital Anxiety and Depression Scale (HADS), we analyzed the correlation of anxiety and depression with steatorrhea, appetite, and weight loss in 72 patients with cancer of the esophagus or of the esophagogastric junction, who were treated at our rehabilitation clinic between January 2011 and December 2014. In addition, effectiveness of psychological interviews was analyzed. Results We have evaluable anxiety questionnaires from 51 patients showing a median anxiety value of 5 (range 0-13). As for the depression, results from evaluable questionnaires of 54 patients also showed a median value of 5 (range 0-15). Increased anxiety and depression values (> 7) were observed in 25.4% and 37.0% of the patients respectively. Patients who were admitted with steatorrhea for rehabilitation showed a statistically higher anxiety value (median 6.3 vs. 4.7, p < 0.05), reduced appetite, and a weight loss above 15 kg depicting a correlation to anxiety and depression. Psychological conversations helped lowering the depression but had no influence on anxiety. Conclusions Impairments after cancer treatment, such as steatorrhea, appetite loss, and weight loss, should be interpreted as an alarm signal and should necessitate screening for increased anxiety and depression. Psychological therapy can help improving the extent of the depression. New York Springer 2019 5 Journal of gastrointestinal cancer 51 1 30 34 10.1007/s12029-018-00193-7 Department Sport- und Gesundheitswissenschaften OPUS4-61126 Wissenschaftlicher Artikel Tarazona, Natalia A.; Machatschek, Rainhard Gabriel; Lendlein, Andreas Unraveling the interplay between abiotic hydrolytic degradation and crystallization of bacterial polyesters comprising short and medium side-chain-length Polyhydroxyalkanoates Polyhydroxyalkanoates (PHAs) have attracted attention as degradable (co)polyesters which can be produced by microorganisms with variations in the side chain. This structural variation influences not only the thermomechanical properties of the material but also its degradation behavior. Here, we used Langmuir monolayers at the air-water (A-W) interface as suitable models for evaluating the abiotic degradation of two PHAs with different side-chain lengths and crystallinity. By controlling the polymer state (semi crystalline, amorphous), the packing density, the pH, and the degradation mechanism, we could draw several significant conclusions. (i) The maximum degree of crystallinity for a PHA film to be efficiently degraded up to pH = 12.3 is 40%. (ii) PHA made of repeating units with shorter side-chain length are more easily hydrolyzed under alkaline conditions. The efficiency of alkaline hydrolysis decreased by about 65% when the polymer was 40% crystalline. (iii) In PHA films with a relatively high initial crystallinity, abiotic degradation initiated a chemicrystallization phenomenon, detected as an increase in the storage modulus (E'). This could translate into an increase in brittleness and reduction in the material degradability. Finally, we demonstrate the stability of the measurement system for long-term experiments, which allows degradation conditions for polymers that could closely simulate real-time degradation. Washington American Chemical Society 2019 11 Biomacromolecules : an interdisciplinary journal focused at the interface of polymer science and the biological sciences 21 2 761 771 10.1021/acs.biomac.9b01458 Institut für Biochemie und Biologie OPUS4-60343 Wissenschaftlicher Artikel Eibl, Eva P. S.; Hainzl, Sebastian; Vesely, Nele I. K.; Walter, Thomas R.; Jousset, Philippe; Hersir, Gylfi Pall; Dahm, Torsten Eruption interval monitoring at strokkur Geyser, Iceland Geysers are hot springs whose frequency of water eruptions remain poorly understood. We set up a local broadband seismic network for 1 year at Strokkur geyser, Iceland, and developed an unprecedented catalog of 73,466 eruptions. We detected 50,135 single eruptions but find that the geyser is also characterized by sets of up to six eruptions in quick succession. The number of single to sextuple eruptions exponentially decreased, while the mean waiting time after an eruption linearly increased (3.7 to 16.4 min). While secondary eruptions within double to sextuple eruptions have a smaller mean seismic amplitude, the amplitude of the first eruption is comparable for all eruption types. We statistically model the eruption frequency assuming discharges proportional to the eruption multiplicity and a constant probability for subsequent events within a multituple eruption. The waiting time after an eruption is predictable but not the type or amplitude of the next one.
Plain Language Summary Geysers are springs that often erupt in hot water fountains. They erupt more often than volcanoes but are quite similar. Nevertheless, it is poorly understood how often volcanoes and also geysers erupt. We created a list of 73,466 eruption times of Strokkur geyser, Iceland, from 1 year of seismic data. The geyser erupted one to six times in quick succession. We found 50,135 single eruptions but only 1 sextuple eruption, while the mean waiting time increased from 3.7 min after single eruptions to 16.4 min after sextuple eruptions. Mean amplitudes of each eruption type were higher for single eruptions, but all first eruptions in a succession were similar in height. Assuming a constant heat inflow at depth, we can predict the waiting time after an eruption but not the type or amplitude of the next one. Washington American Geophysical Union 2019 10 Geophysical research letters 47 1 10.1029/2019GL085266 Institut für Geowissenschaften OPUS4-60145 Wissenschaftlicher Artikel Malinova, Irina; Kössler, Stella; Orawetz, Tom; Matthes, Ulrike; Orzechowski, Slawomir; Koch, Anke; Fettke, Jörg Identification of two Arabidopsis thaliana plasma membrane transporters able to transport glucose 1-phosphate Primary carbohydrate metabolism in plants includes several sugar and sugar-derivative transport processes. Over recent years, evidences have shown that in starch-related transport processes, in addition to glucose 6-phosphate, maltose, glucose and triose-phosphates, glucose 1-phosphate also plays a role and thereby increases the possible fluxes of sugar metabolites in planta. In this study, we report the characterization of two highly similar transporters, At1g34020 and At4g09810, in Arabidopsis thaliana, which allow the import of glucose 1-phosphate through the plasma membrane. Both transporters were expressed in yeast and were biochemically analyzed to reveal an antiport of glucose 1-phosphate/phosphate. Furthermore, we showed that the apoplast of Arabidopsis leaves contained glucose 1-phosphate and that the corresponding mutant of these transporters had higher glucose 1-phosphate amounts in the apoplast and alterations in starch and starch-related metabolism. Oxford Oxford University Press 2019 12 Plant & cell physiology 61 2 381 392 10.1093/pcp/pcz206 Institut für Biochemie und Biologie OPUS4-61471 Wissenschaftlicher Artikel Machatschek, Rainhard Gabriel; Lendlein, Andreas Fundamental insights in PLGA degradation from thin film studies Poly(lactide-co-glycolide)s are commercially available degradable implant materials, which are typically selected based on specifications given by the manufacturer, one of which is their molecular weight. Here, we address the question whether variations in the chain length and their distribution affect the degradation behavior of Poly[(rac-lactide)-co-glycolide]s (PDLLGA). The hydrolysis was studied in ultrathin films at the air-water interface in order to rule out any morphological effects. We found that both for purely hydrolytic degradation as well as under enzymatic catalysis, the molecular weight has very little effect on the overall degradation kinetics of PDLLGAs. The quantitative analysis suggested a random scission mechanism. The monolayer experiments showed that an acidic micro-pH does not accelerate the degradation of PDLLGAs, in contrast to alkaline conditions. The degradation experiments were combined with interfacial rheology measurements, which showed a drastic decrease of the viscosity at little mass loss. The extrapolated molecular weight behaved similar to the viscosity, dropping to a value near to the solubility limit of PDLLGA oligomers before mass loss set in. This observation suggests a solubility controlled degradation of PDLLGA. Conclusively, the molecular weight affects the degradation of PDLLGA devices mostly in indirect ways, e.g. by determining their morphology and porosity during fabrication. Our study demonstrates the relevance of the presented Langmuir degradation method for the design of controlled release systems. New York Elsevier 2019 9 Journal of controlled release : official journal of the Controlled Release Society and of the Japanese Society of Drug Delivery Systems 319 276 284 10.1016/j.jconrel.2019.12.044 Institut für Chemie OPUS4-61796 Buch (Monographie) Musil, Andreas; Burchard, Daniel Klausurenkurs im Europarecht Jetzt mit neuen Fällen! Die 5. Auflage enhält einen neuen Fall zur PKW-Maut und einen neuen Fall zum kirchlichen Arbeitsrecht. Die Konzeption: Dieser Klausurenkurs ist die optimale Ergänzung zum Standardlehrbuch zum Europarecht von Streinz. Angesprochen werden neben den Studierenden des Schwerpunktbereichs Internationales Recht/Europarecht, (deren Bedürfnisse durch das Buch in vollem Umfang abgedeckt werden) auch und insbesondere Pflichtfachstudierende. Sie erhalten das nötige Rüstzeug für examensrelevante Fragestellungen im Europarecht und erhalten einen Eindruck von der Vielfalt von Aufgabenstellungen, den unterschiedlichen Schwierigkeitsgraden sowie den damit verbundenen Erwartungshaltungen an den Klausurschreiber. Der Inhalt im Einzelnen: Der Band ist in drei Kapitel untergliedert. Zu Beginn werden die Arbeitsmöglichkeiten für die beiden angesprochenen Zielgruppen aufgezeigt. Im 2. Kapitel werden sodann auf abstrakter Ebene diejenigen Klausurkonstellationen dargestellt, die im Gemeinschaftsrecht relevant werden können. Hier findet der Leser den allgemeinen Zugang zu klausurrelevanten Fallgestaltungen. Den Kern des Buches bildet der Klausurenteil im 3. Kapitel. Er enthält 23 Fälle, welchen jeweils Leitentscheidungen des EuGH und anderer Gerichte zugrunde liegen. Die entschiedenen Fälle werden klausurtechnisch aufbereitet und um angrenzende Problempunkte ergänzt, so dass jeweils komplette Klausuraufgaben entstehen. Die Verwendungsmöglichkeit als Prüfungsleistung (Schwerpunkt- oder Pflichtfachklausur) wird im Rahmen der Vorüberlegungen zu jedem Fall erläutert. Abgerundet wird der Klausurenteil durch entsprechende Prüfungsschemata. 5., neu bearbeitete Heidelberg C.F. Müller 2019 XXI, 482 Jura auf den [Punkt] gebracht 978-3-8114-4754-7 Öffentliches Recht OPUS4-60142 Wissenschaftlicher Artikel Solger, Franziska; Kunz, Tobias C.; Fink, Julian; Paprotka, Kerstin; Pfister, Pauline; Hagen, Franziska; Schumacher, Fabian; Kleuser, Burkhard; Seibel, Jürgen; Rudel, Thomas A role of sphingosine in the intracellular survival of Neisseria gonorrhoeae Obligate human pathogenic Neisseria gonorrhoeae are the second most frequent bacterial cause of sexually transmitted diseases. These bacteria invade different mucosal tissues and occasionally disseminate into the bloodstream. Invasion into epithelial cells requires the activation of host cell receptors by the formation of ceramide-rich platforms. Here, we investigated the role of sphingosine in the invasion and intracellular survival of gonococci. Sphingosine exhibited an anti-gonococcal activity in vitro. We used specific sphingosine analogs and click chemistry to visualize sphingosine in infected cells. Sphingosine localized to the membrane of intracellular gonococci. Inhibitor studies and the application of a sphingosine derivative indicated that increased sphingosine levels reduced the intracellular survival of gonococci. We demonstrate here, that sphingosine can target intracellular bacteria and may therefore exert a direct bactericidal effect inside cells. Lausanne Frontiers Media 2019 12 Frontiers in Cellular and Infection Microbiology 10 10.3389/fcimb.2020.00215 Institut für Ernährungswissenschaft OPUS4-61633 Buch (Monographie) Görtemaker, Manfred; Hübener, Kristina Schwert der Justiz Das Gerichtsvollzieherwesen erlebte in den zurückliegenden 200 Jahren eine wechselhafte Entwicklung. Die Gerichtsvollzieher standen und stehen seit jeher zwischen verschiedenen Polen: zwischen Selbstständigkeit und Abhängigkeit, zwischen Eigenverantwortung und Weisungsgebundenheit, zwischen moderatem Mittlertum und einem rein exekutiven Verständnis des Amtes als »Schwert der Justiz«. Die Beiträge dieses Bandes beschreiben die Geschichte des Gerichtsvollzieherwesens von seinen Anfängen im territorial zersplitterten Deutschland um 1800 bis in die heutige Zeit. Berlin be.bra wissenschafts Verlag 2019 256 Brandenburgische Historische Kommission: Einzelveröffentlichungen der Brandenburgischen Historischen Kommission e.V. 21 978-3-95410-242-6 Historisches Institut OPUS4-61638 Wissenschaftlicher Artikel Hübener, Kristina Vollstreckungsrechtlicher Erziehungsauftrag in der DDR 1949 bis 1989/90 Berlin be.bra wissenschafts Verlag 2019 12 Schwert der Justiz : das Gerichtsvollzieherwesen in Deutschland von 1800 bis zur Gegenwart 978-3-95410-242-6 129 141 Historisches Institut OPUS4-61637 Wissenschaftlicher Artikel Weigle, Jeremias Die Organisation des Gerichtsvolzieherwesen 1945-1949 Berlin be.bra wissenschafts Verlag 2019 26 Schwert der Justiz : das Gerichtsvollzieherwesen in Deutschland von 1800 bis zur Gegenwart 978-3-95410-242-6 101 127 Historisches Institut OPUS4-61635 Wissenschaftlicher Artikel Zare-Hamedani, Naghme Gerichtsvollzieher im "Dritten Reich" Berlin be.bra wissenschafts Verlag 2019 Schwert der Justiz : das Gerichtsvollzieherwesen in Deutschland von 1800 bis zur Gegenwart 978-3-95410-242-6 Historisches Institut OPUS4-61634 Wissenschaftlicher Artikel Görtemaker, Manfred Vorwort Berlin be.bra wissenschafts Verlag 2019 3 Schwert der Justiz : das Gerichtsvollzieherwesen in Deutschland von 1800 bis zur Gegenwart 978-3-95410-242-6 7 9 Historisches Institut OPUS4-60373 Buch (Monographie) Assmann, Dorothea Fälle zum Zivilprozessrecht 3., neu bearbeitete München C.H. Beck 2019 XVI, 298 Juristische Fall-Lösungen 978-3-406-71855-7 Bürgerliches Recht OPUS4-60942 Wissenschaftlicher Artikel Heissel, Andreas; Pietrek, Anou F.; Rapp, Michael Armin; Heinzel, Stephan; Williams, Geoffrey Perceived health care climate of older people attending an exercise program The role of perceived need support from exercise professionals in improving mental health was examined in a sample of older adults, thereby validating the short Health Care Climate Questionnaire. A total of 491 older people (M = 72.68 years; SD = 5.47) attending a health exercise program participated in this study. Cronbach's alpha was found to be high (alpha = .90). Satisfaction with the exercise professional correlated moderately with the short Health Care Climate Questionnaire mean value (r = .38; p < .01). The mediator analyses yielded support for the self-determination theory process model in older adults by showing both basic need satisfaction and frustration as mediating variables between perceived autonomy support and depressive symptoms. The short Health Care Climate Questionnaire is an economical instrument for assessing basic need satisfaction provided by the exercise therapist from the participant's perspective. Furthermore, this cross-sectional study supported the link from coaching style to the satisfaction/frustration of basic psychological needs, which in turn, predicted mental health. Analyses of criterion validity suggest a revision of the construct by integrating need frustration. Champaign Human Kinetics Publ. 2019 11 Journal of aging and physical activity : JAPA ; the official journal of the International Society for Aging and Physical Activity 28 2 276 286 10.1123/japa.2018-0350 Department Sport- und Gesundheitswissenschaften OPUS4-61239 Wissenschaftlicher Artikel Höhle, Barbara; Bijeljac-Babic, Ranka; Nazzi, Thierry Variability and stability in early language acquisition Many human infants grow up learning more than one language simultaneously but only recently has research started to study early language acquisition in this population more systematically. The paper gives an overview on findings on early language acquisition in bilingual infants during the first two years of life and compares these findings to current knowledge on early language acquisition in monolingual infants. Given the state of the research, the overview focuses on research on phonological and early lexical development in the first two years of life. We will show that the developmental trajectory of early language acquisition in these areas is very similar in mono- and bilingual infants suggesting that these early steps into language are guided by mechanisms that are rather robust against the differences in the conditions of language exposure that mono- and bilingual infants typically experience. New York Cambridge Univ. Press 2019 16 Bilingualism : language and cognition 23 1 56 71 10.1017/S1366728919000348 Department Linguistik OPUS4-61253 Wissenschaftlicher Artikel Cervantes, Sebastian; Shprits, Yuri Y.; Aseev, Nikita A.; Drozdov, Alexander Y.; Castillo Tibocha, Angelica Maria; Stolle, Claudia Identifying radiation belt electron source and loss processes by assimilating spacecraft data in a three-dimensional diffusion model Data assimilation aims to blend incomplete and inaccurate data with physics-based dynamical models. In the Earth's radiation belts, it is used to reconstruct electron phase space density, and it has become an increasingly important tool in validating our current understanding of radiation belt dynamics, identifying new physical processes, and predicting the near-Earth hazardous radiation environment. In this study, we perform reanalysis of the sparse measurements from four spacecraft using the three-dimensional Versatile Electron Radiation Belt diffusion model and a split-operator Kalman filter over a 6-month period from 1 October 2012 to 1 April 2013. In comparison to previous works, our 3-D model accounts for more physical processes, namely, mixed pitch angle-energy diffusion, scattering by Electromagnetic Ion Cyclotron waves, and magnetopause shadowing. We describe how data assimilation, by means of the innovation vector, can be used to account for missing physics in the model. We use this method to identify the radial distances from the Earth and the geomagnetic conditions where our model is inconsistent with the measured phase space density for different values of the invariants mu and K. As a result, the Kalman filter adjusts the predictions in order to match the observations, and we interpret this as evidence of where and when additional source or loss processes are active. The current work demonstrates that 3-D data assimilation provides a comprehensive picture of the radiation belt electrons and is a crucial step toward performing reanalysis using measurements from ongoing and future missions. Washington American Geophysical Union 2019 16 Journal of geophysical research : Space physics 125 1 10.1029/2019JA027514 Institut für Physik und Astronomie OPUS4-61252 Wissenschaftlicher Artikel Blasius, Bernd; Rudolf, Lars; Weithoff, Guntram; Gaedke, Ursula; Fussmann, Gregor F. Long-term cyclic persistence in an experimental predator-prey system Predator-prey cycles rank among the most fundamental concepts in ecology, are predicted by the simplest ecological models and enable, theoretically, the indefinite persistence of predator and prey(1-4). However, it remains an open question for how long cyclic dynamics can be self-sustained in real communities. Field observations have been restricted to a few cycle periods(5-8) and experimental studies indicate that oscillations may be short-lived without external stabilizing factors(9-19). Here we performed microcosm experiments with a planktonic predator-prey system and repeatedly observed oscillatory time series of unprecedented length that persisted for up to around 50 cycles or approximately 300 predator generations. The dominant type of dynamics was characterized by regular, coherent oscillations with a nearly constant predator-prey phase difference. Despite constant experimental conditions, we also observed shorter episodes of irregular, non-coherent oscillations without any significant phase relationship. However, the predator-prey system showed a strong tendency to return to the dominant dynamical regime with a defined phase relationship. A mathematical model suggests that stochasticity is probably responsible for the reversible shift from coherent to non-coherent oscillations, a notion that was supported by experiments with external forcing by pulsed nutrient supply. Our findings empirically demonstrate the potential for infinite persistence of predator and prey populations in a cyclic dynamic regime that shows resilience in the presence of stochastic events. London Nature Publ. Group 2019 18 Nature : the international weekly journal of science 577 7789 226 230 10.1038/s41586-019-1857-0 Institut für Physik und Astronomie OPUS4-61166 Wissenschaftlicher Artikel Hehn, Jennifer; Mendez, Daniel; Uebernickel, Falk; Brenner, Walter; Broy, Manfred On integrating design thinking for human-centered requirements engineering We elaborate on the possibilities and needs to integrate design thinking into requirements engineering, drawing from our research and project experiences. We suggest three approaches for tailoring and integrating design thinking and requirements engineering with complementary synergies and point at open challenges for research and practice. Los Alamitos Inst. of Electr. and Electronics Engineers 2019 7 IEEE software 37 2 25 31 10.1109/MS.2019.2957715 Hasso-Plattner-Institut für Digital Engineering gGmbH OPUS4-60177 Wissenschaftlicher Artikel Li, Changsheng; Chen, Gangjin; Qiu, Xunlin; Gao, Meng; Gerhard, Reimund Modified polytetrafluoroethylene Three poly(tetrafluoroethylene-hexafluoropropylene-vinylidenefluoride) (TFE-HFP-VDF or THV) terpolymers (Dyneon (R)) with different monomer ratios are investigated to demonstrate the concept of "modified" PTFE for space-charge electrets. HFP and VDF monomers distort the highly ordered PTFE molecules, which effectively enhances processability and adversely affects space-charge storage. Particularly, VDF component renders the material polar and probably also more conductive, partially undermining the space-charge-storage capabilities of PTFE. Nevertheless, the terpolymer THV815 with a TFE/HFP/VDF wt% ratio of 76.1/10.9/13 combines easy processability and relatively good space-charge stability. Our results shed light on novel concepts for space-charge electret materials with enhanced processing properties and reasonable charge-storage capabilities. Bristol IOP Publ. Ltd. 2019 5 Applied physics express : APEX 13 1 10.7567/1882-0786/ab5b23 Institut für Physik und Astronomie OPUS4-60144 Wissenschaftlicher Artikel Chen, Jun; Liu, Rui; Liu, Kai; Awasthi, Arun Kumar; Zhang, Peijin; Wang, Yuming; Kliem, Bernhard Extreme-ultraviolet late phase of solar flares A second peak in the extreme ultraviolet sometimes appears during the gradual phase of solar flares, which is known as the EUV late phase (ELP). Stereotypically ELP is associated with two separated sets of flaring loops with distinct sizes, and it has been debated whether ELP is caused by additional heating or extended plasma cooling in the longer loop system. Here we carry out a survey of 55 M-and-above GOES-class flares with ELP during 2010-2014. Based on the flare-ribbon morphology, these flares are categorized as circular-ribbon (19 events), two-ribbon (23 events), and complex-ribbon (13 events) flares. Among them, 22 events (40%) are associated with coronal mass ejections, while the rest are confined. An extreme ELP, with the late-phase peak exceeding the main-phase peak, is found in 48% of two-ribbon flares, 37% of circular-ribbon flares, and 31% of complex-ribbon flares, suggesting that additional heating is more likely present during ELP in two-ribbon than in circular-ribbon flares. Overall, cooling may be the dominant factor causing the delay of the ELP peak relative to the main-phase peak, because the loop system responsible for the ELP emission is generally larger than, and well separated from, that responsible for the main-phase emission. All but one of the circular-ribbon flares can be well explained by a composite "dome-plate" quasi-separatrix layer (QSL). Only half of these show a magnetic null point, with its fan and spine embedded in the dome and plate, respectively. The dome-plate QSL, therefore, is a general and robust structure characterizing circular-ribbon flares. London Institute of Physics Publ. 2019 10 The astrophysical journal : an international review of spectroscopy and astronomical physics 890 2 10.3847/1538-4357/ab6def Institut für Physik und Astronomie OPUS4-60935 Wissenschaftlicher Artikel Bär, Markus; Großmann, Robert; Heidenreich, Sebastian; Peruani, Fernando Self-propelled rods A wide range of experimental systems including gliding, swarming and swimming bacteria, in vitro motility assays, and shaken granular media are commonly described as self-propelled rods. Large ensembles of those entities display a large variety of self-organized, collective phenomena, including the formation of moving polar clusters, polar and nematic dynamic bands, mobility-induced phase separation, topological defects, and mesoscale turbulence, among others. Here, we give a brief survey of experimental observations and review the theoretical description of self-propelled rods. Our focus is on the emergent pattern formation of ensembles of dry self-propelled rods governed by short-ranged, contact mediated interactions and their wet counterparts that are also subject to long-ranged hydrodynamic flows. Altogether, self-propelled rods provide an overarching theme covering many aspects of active matter containing well-explored limiting cases. Their collective behavior not only bridges the well-studied regimes of polar selfpropelled particles and active nematics, and includes active phase separation, but also reveals a rich variety of new patterns. Palo Alto Annual Reviews 2019 26 Annual review of condensed matter physics 11 441 466 10.1146/annurev-conmatphys-031119-050611 Institut für Physik und Astronomie OPUS4-61060 Wissenschaftlicher Artikel Caliendo, Marco; Tübbicke, Stefan New evidence on long-term effects of start-up subsidies The German start-up subsidy (SUS) program for the unemployed has recently undergone a major makeover, altering its institutional setup, adding an additional layer of selection and leading to ambiguous predictions of the program's effectiveness. Using propensity score matching (PSM) as our main empirical approach, we provide estimates of long-term effects of the post-reform subsidy on individual employment prospects and labor market earnings up to 40 months after entering the program. Our results suggest large and persistent long-term effects of the subsidy on employment probabilities and net earned income. These effects are larger than what was estimated for the pre-reform program. Extensive sensitivity analyses within the standard PSM framework reveal that the results are robust to different choices regarding the implementation of the weighting procedure and also with respect to deviations from the conditional independence assumption. As a further assessment of the results' sensitivity, we go beyond the standard selection-on-observables approach and employ an instrumental variable setup using regional variation in the likelihood of receiving treatment. Here, we exploit the fact that the reform increased the discretionary power of local employment agencies in allocating active labor market policy funds, allowing us to obtain a measure of local preferences for SUS as the program of choice. The results based on this approach give rise to similar estimates. Thus, our results indicating that SUS are still an effective active labor market program after the reform do not appear to be driven by "hidden bias." Heidelberg Physica-Verlag 2019 27 Empirical economics 59 4 1605 1631 10.1007/s00181-019-01701-9 Fachgruppe Volkswirtschaftslehre OPUS4-60961 Wissenschaftlicher Artikel Mink, Albert; McHardy, Christopher; Bressel, Lena; Rauh, Cornelia; Krause, Mathias J. Radiative transfer lattice Boltzmann methods The numerical prediction of radiative transport is a challenging task due to the complexity of the radiative transport equation. We apply the lattice Boltzmann method (LBM), originally developed for fluid flow problems, to solve the radiative transport in volume. One model (meso RTLBM) is derived directly from a discretization of the radiative transport equation, yielding in a precise but numerical costly scheme. The second model (macro RTLBM) solves the Helmholtz equation, which is a proper approximation for highly scattering volumes. Both numerical algorithms are validated against Monte-Carlo data for a set of 35 optical parameters, which correspond to radiative transport ranging from ballistic to diffuse regimes. Together with a set of four benchmark simulations, the comprehensive validation concludes the overall quality and detects asymptotic trends for radiative transport LBM. Furthermore, an accuracy map is presented, which summarizes the error for all parameters. This graph allows to determine the validity range for both radiative transport LBM at a glance. Finally, comprehensive guidelines are formulated to facilitate the choice of the radiative transport LBM model. Oxford Pergamon Press 2019 Journal of quantitative spectroscopy & radiative transfer 243 10.1016/j.jqsrt.2019.106810 Institut für Chemie OPUS4-60639 Wissenschaftlicher Artikel Voeth, Markus; Herbst, Uta; Haggenmüller, Sandra; Weber, Marie-Christin Wie verhandeln deutsche Manager? Köln Dr. Otto Schmidt 2019 4 Zeitschrift für Konfliktmanagement 23 1 21 24 10.9785/zkm-2020-230107 Wirtschaftswissenschaften OPUS4-47326 misc Kotthoff, Lisa; Lisec, Jan; Schwerdtle, Tanja; Koch, Matthias Prediction of transformation products of monensin by electrochemistry compared to microsomal assay and hydrolysis The knowledge of transformation pathways and identification of transformation products (TPs) of veterinary drugs is important for animal health, food, and environmental matters. The active agent Monensin (MON) belongs to the ionophore antibiotics and is widely used as a veterinary drug against coccidiosis in broiler farming. However, no electrochemically (EC) generated TPs of MON have been described so far. In this study, the online coupling of EC and mass spectrometry (MS) was used for the generation of oxidative TPs. EC-conditions were optimized with respect to working electrode material, solvent, modifier, and potential polarity. Subsequent LC/HRMS (liquid+ chromatography/high resolution mass spectrometry) and MS/MS experiments were performed to identify the structures of derived TPs by a suspected target analysis. The obtained EC-results were compared to TPs observed in metabolism tests with microsomes and hydrolysis experiments of MON. Five previously undescribed TPs of MON were identified in our EC/MS based study and one TP, which was already known from literature and found by a microsomal assay, could be confirmed. Two and three further TPs were found as products in microsomal tests and following hydrolysis, respectively. We found decarboxylation, O-demethylation and acid-catalyzed ring-opening reactions to be the major mechanisms of MON transformation 2019 12 Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe 1340 urn:nbn:de:kobv:517-opus4-473262 10.25932/publishup-47326 Institut für Ernährungswissenschaft OPUS4-47327 misc Rancan, Fiorenza; Volkmann, Hildburg; Giulbudagian, Michael; Schumacher, Fabian; Stanko, Jessica Isolde; Kleuser, Burkhard; Blume-Peytavi, Ulrike; Calderón, Marcelo; Vogt, Annika Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels Polyglycerol-based thermoresponsive nanogels (tNGs) have been shown to have excellent skin hydration properties and to be valuable delivery systems for sustained release of drugs into skin. In this study, we compared the skin penetration of tacrolimus formulated in tNGs with a commercial 0.1% tacrolimus ointment. The penetration of the drug was investigated in ex vivo abdominal and breast skin, while different methods for skin barrier disruption were investigated to improve skin permeability or simulate inflammatory conditions with compromised skin barrier. The amount of penetrated tacrolimus was measured in skin extracts by liquid chromatography tandem-mass spectrometry (LC-MS/MS), whereas the inflammatory markers IL-6 and IL-8 were detected by enzyme-linked immunosorbent assay (ELISA). Higher amounts of tacrolimus penetrated in breast as compared to abdominal skin or in barrier-disrupted as compared to intact skin, confirming that the stratum corneum is the main barrier for tacrolimus skin penetration. The anti-proliferative effect of the penetrated drug was measured in skin tissue/Jurkat cells co-cultures. Interestingly, tNGs exhibited similar anti-proliferative effects as the 0.1% tacrolimus ointment. We conclude that polyglycerol-based nanogels represent an interesting alternative to paraffin-based formulations for the treatment of inflammatory skin conditions. 2019 14 Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe 1339 urn:nbn:de:kobv:517-opus4-473270 10.25932/publishup-47327 Institut für Ernährungswissenschaft OPUS4-47329 misc Ayzel, Georgy; Varentsova, Natalia; Erina, Oxana; Sokolov, Dmitriy; Kurochkina, Liubov; Moreydo, Vsevolod OpenForecast The development and deployment of new operational runoff forecasting systems are a strong focus of the scientific community due to the crucial importance of reliable and timely runoff predictions for early warnings of floods and flashfloods for local businesses and communities. OpenForecast, the first operational runoff forecasting system in Russia, open for public use, is presented in this study. We developed OpenForecast based only on open-source software and data-GR4J hydrological model, ERA-Interim meteorological reanalysis, and ICON deterministic short-range meteorological forecasts. Daily forecasts were generated for two basins in the European part of Russia. Simulation results showed a limited efficiency in reproducing the spring flood of 2019. Although the simulations managed to capture the timing of flood peaks, they failed in estimating flood volume. However, further implementation of the parsimonious data assimilation technique significantly alleviates simulation errors. The revealed limitations of the proposed operational runoff forecasting system provided a foundation to outline its further development and improvement. 2019 17 Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe 1338 urn:nbn:de:kobv:517-opus4-473295 10.25932/publishup-47329 Institut für Geowissenschaften OPUS4-47331 misc Brieger, Frederic; Herzschuh, Ulrike; Pestryakova, Luidmila Agafyevna; Bookhagen, Bodo; Zakharov, Evgenii S.; Kruse, Stefan Advances in the derivation of Northeast Siberian forest metrics using high-resolution UAV-based photogrammetric point clouds Forest structure is a crucial component in the assessment of whether a forest is likely to act as a carbon sink under changing climate. Detailed 3D structural information about the tundra-taiga ecotone of Siberia is mostly missing and still underrepresented in current research due to the remoteness and restricted accessibility. Field based, high-resolution remote sensing can provide important knowledge for the understanding of vegetation properties and dynamics. In this study, we test the applicability of consumer-grade Unmanned Aerial Vehicles (UAVs) for rapid calculation of stand metrics in treeline forests. We reconstructed high-resolution photogrammetric point clouds and derived canopy height models for 10 study sites from NE Chukotka and SW Yakutia. Subsequently, we detected individual tree tops using a variable-window size local maximum filter and applied a marker-controlled watershed segmentation for the delineation of tree crowns. With this, we successfully detected 67.1% of the validation individuals. Simple linear regressions of observed and detected metrics show a better correlation (R2) and lower relative root mean square percentage error (RMSE%) for tree heights (mean R2 = 0.77, mean RMSE% = 18.46%) than for crown diameters (mean R2 = 0.46, mean RMSE% = 24.9%). The comparison between detected and observed tree height distributions revealed that our tree detection method was unable to representatively identify trees <2 m. Our results show that plot sizes for vegetation surveys in the tundra-taiga ecotone should be adapted to the forest structure and have a radius of >15-20 m to capture homogeneous and representative forest stands. Additionally, we identify sources of omission and commission errors and give recommendations for their mitigation. In summary, the efficiency of the used method depends on the complexity of the forest's stand structure. 2019 24 Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe 1337 urn:nbn:de:kobv:517-opus4-473318 10.25932/publishup-47331 Institut für Geowissenschaften OPUS4-47341 misc Perera, Upeksha; Böckmann, Christine Solutions of direct and inverse even-order Sturm-Liouville problems using Magnus expansion In this paper Lie group method in combination with Magnus expansion is utilized to develop a universal method applicable to solving a Sturm-Liouville problem (SLP) of any order with arbitrary boundary conditions. It is shown that the method has ability to solve direct regular (and some singular) SLPs of even orders (tested for up to eight), with a mix of (including non-separable and finite singular endpoints) boundary conditions, accurately and efficiently. The present technique is successfully applied to overcome the difficulties in finding suitable sets of eigenvalues so that the inverse SLP problem can be effectively solved. The inverse SLP algorithm proposed by Barcilon (1974) is utilized in combination with the Magnus method so that a direct SLP of any (even) order and an inverse SLP of order two can be solved effectively. 2019 24 Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe 1336 urn:nbn:de:kobv:517-opus4-473414 10.25932/publishup-47341 Institut für Mathematik OPUS4-59914 Wissenschaftlicher Artikel Perera, Upeksha; Böckmann, Christine Solutions of Direct and Inverse Even-Order Sturm-Liouville Problems Using Magnus Expansion In this paper Lie group method in combination with Magnus expansion is utilized to develop a universal method applicable to solving a Sturm-Liouville problem (SLP) of any order with arbitrary boundary conditions. It is shown that the method has ability to solve direct regular (and some singular) SLPs of even orders (tested for up to eight), with a mix of (including non-separable and finite singular endpoints) boundary conditions, accurately and efficiently. The present technique is successfully applied to overcome the difficulties in finding suitable sets of eigenvalues so that the inverse SLP problem can be effectively solved. The inverse SLP algorithm proposed by Barcilon (1974) is utilized in combination with the Magnus method so that a direct SLP of any (even) order and an inverse SLP of order two can be solved effectively. Basel, Schweiz MDPI 2019 24 Mathematics 7 6 10.3390/math7060544 Institut für Mathematik OPUS4-47343 misc Pornsawad, Pornsarp; Sapsakul, Nantawan; Böckmann, Christine A modified asymptotical regularization of nonlinear ill-posed problems In this paper, we investigate the continuous version of modified iterative Runge-Kutta-type methods for nonlinear inverse ill-posed problems proposed in a previous work. The convergence analysis is proved under the tangential cone condition, a modified discrepancy principle, i.e., the stopping time T is a solution of ∥𝐹(𝑥𝛿(𝑇))−𝑦𝛿∥=𝜏𝛿+ for some 𝛿+>𝛿, and an appropriate source condition. We yield the optimal rate of convergence. 2019 19 Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe 1335 urn:nbn:de:kobv:517-opus4-473433 10.25932/publishup-47343 Institut für Mathematik