@misc{KuekenSommerYanevaRoderetal.2018, author = {K{\"u}ken, Anika and Sommer, Frederik and Yaneva-Roder, Liliya and Mackinder, Luke C.M. and H{\"o}hne, Melanie and Geimer, Stefan and Jonikas, Martin C. and Schroda, Michael and Stitt, Mark and Nikoloski, Zoran and Mettler-Altmann, Tabea}, title = {Effects of microcompartmentation on flux distribution and metabolic pools in Chlamydomonas reinhardtii chloroplasts}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, number = {1122}, issn = {1866-8372}, doi = {10.25932/publishup-44635}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-446358}, pages = {25}, year = {2018}, abstract = {Cells and organelles are not homogeneous but include microcompartments that alter the spatiotemporal characteristics of cellular processes. The effects of microcompartmentation on metabolic pathways are however difficult to study experimentally. The pyrenoid is a microcompartment that is essential for a carbon concentrating mechanism (CCM) that improves the photosynthetic performance of eukaryotic algae. Using Chlamydomonas reinhardtii, we obtained experimental data on photosynthesis, metabolites, and proteins in CCM-induced and CCM-suppressed cells. We then employed a computational strategy to estimate how fluxes through the Calvin-Benson cycle are compartmented between the pyrenoid and the stroma. Our model predicts that ribulose-1,5-bisphosphate (RuBP), the substrate of Rubisco, and 3-phosphoglycerate (3PGA), its product, diffuse in and out of the pyrenoid, respectively, with higher fluxes in CCM-induced cells. It also indicates that there is no major diffusional barrier to metabolic flux between the pyrenoid and stroma. Our computational approach represents a stepping stone to understanding microcompartmentalized CCM in other organisms.}, language = {en} } @article{KuehneFischerJeglinskiMende2022, author = {K{\"u}hne, Katharina and Fischer, Martin H. and Jeglinski-Mende, Melinda A.}, title = {During the COVID-19 pandemic participants prefer settings with a face mask, no interaction and at a closer distance}, series = {Scientific Reports}, volume = {12}, journal = {Scientific Reports}, publisher = {Springer Nature}, address = {Berlin}, issn = {2045-2322}, doi = {10.1038/s41598-022-16730-1}, pages = {1 -- 12}, year = {2022}, abstract = {Peripersonal space is the space surrounding our body, where multisensory integration of stimuli and action execution take place. The size of peripersonal space is flexible and subject to change by various personal and situational factors. The dynamic representation of our peripersonal space modulates our spatial behaviors towards other individuals. During the COVID-19 pandemic, this spatial behavior was modified by two further factors: social distancing and wearing a face mask. Evidence from offline and online studies on the impact of a face mask on pro-social behavior is mixed. In an attempt to clarify the role of face masks as pro-social or anti-social signals, 235 observers participated in the present online study. They watched pictures of two models standing at three different distances from each other (50, 90 and 150 cm), who were either wearing a face mask or not and were either interacting by initiating a hand shake or just standing still. The observers' task was to classify the model by gender. Our results show that observers react fastest, and therefore show least avoidance, for the shortest distances (50 and 90 cm) but only when models wear a face mask and do not interact. Thus, our results document both pro- and anti-social consequences of face masks as a result of the complex interplay between social distancing and interactive behavior. Practical implications of these findings are discussed.}, language = {en} } @article{ArguellodeSouzaSamprognaMohorGuzmanAriasetal.2023, author = {Arguello de Souza, Felipe Augusto and Samprogna Mohor, Guilherme and Guzman Arias, Diego Alejandro and Sarmento Buarque, Ana Carolina and Taffarello, Denise and Mendiondo, Eduardo Mario}, title = {Droughts in S{\~a}o Paulo}, series = {Urban water journal}, volume = {20}, journal = {Urban water journal}, number = {10}, publisher = {Taylor \& Francis}, address = {London [u.a.]}, issn = {1573-062X}, doi = {10.1080/1573062X.2022.2047735}, pages = {1682 -- 1694}, year = {2023}, abstract = {Literature has suggested that droughts and societies are mutually shaped and, therefore, both require a better understanding of their coevolution on risk reduction and water adaptation. Although the Sao Paulo Metropolitan Region drew attention because of the 2013-2015 drought, this was not the first event. This paper revisits this event and the 1985-1986 drought to compare the evolution of drought risk management aspects. Documents and hydrological records are analyzed to evaluate the hazard intensity, preparedness, exposure, vulnerability, responses, and mitigation aspects of both events. Although the hazard intensity and exposure of the latter event were larger than the former one, the policy implementation delay and the dependency of service areas in a single reservoir exposed the region to higher vulnerability. In addition to the structural and non-structural tools implemented just after the events, this work raises the possibility of rainwater reuse for reducing the stress in reservoirs.}, language = {en} } @article{SchaeferDechAehleetal.2021, author = {Schaefer, Laura and Dech, Silas and Aehle, Markus and Bittmann, Frank}, title = {Disgusting odours affect the characteristics of the adaptive force in contrast to neutral and pleasant odours}, series = {Scientific Reports}, volume = {11}, journal = {Scientific Reports}, publisher = {Springer Nature}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-021-95759-0}, pages = {1 -- 16}, year = {2021}, abstract = {The olfactomotor system is especially investigated by examining the sniffing in reaction to olfactory stimuli. The motor output of respiratory-independent muscles was seldomly considered regarding possible influences of smells. The Adaptive Force (AF) characterizes the capability of the neuromuscular system to adapt to external forces in a holding manner and was suggested to be more vulnerable to possible interfering stimuli due to the underlying complex control processes. The aim of this pilot study was to measure the effects of olfactory inputs on the AF of the hip and elbow flexors, respectively. The AF of 10 subjects was examined manually by experienced testers while smelling at sniffing sticks with neutral, pleasant or disgusting odours. The reaction force and the limb position were recorded by a handheld device. The results show, inter alia, a significantly lower maximal isometric AF and a significantly higher AF at the onset of oscillations by perceiving disgusting odours compared to pleasant or neutral odours (p < 0.001). The adaptive holding capacity seems to reflect the functionality of the neuromuscular control, which can be impaired by disgusting olfactory inputs. An undisturbed functioning neuromuscular system appears to be characterized by a proper length tension control and by an earlier onset of mutual oscillations during an external force increase. This highlights the strong connection of olfaction and motor control also regarding respiratory-independent muscles.}, language = {en} } @article{HaverkampSorgenfreiGiangrisostomietal.2021, author = {Haverkamp, Robert and Sorgenfrei, Nomi and Giangrisostomi, Erika and Neppl, Stefan and K{\"u}hn, Danilo and F{\"o}hlisch, Alexander}, title = {Directional charge delocalization dynamics in semiconducting 2H-MoS2 and metallic 1T-LixMoS2}, series = {Scientific reports}, volume = {11}, journal = {Scientific reports}, number = {1}, publisher = {Macmillan Publishers Limited, part of Springer Nature}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-021-86364-2}, pages = {7}, year = {2021}, abstract = {The layered dichalcogenide MoS2 is relevant for electrochemical Li adsorption/intercalation, in the course of which the material undergoes a concomitant structural phase transition from semiconducting 2H-MoS2 to metallic 1T-LixMoS2. With the core hole clock approach at the S L1 X-ray absorption edge we quantify the ultrafast directional charge transfer of excited S3p electrons in-plane () and out-of-plane (perpendicular to) for 2H-MoS2 as tau 2H,=0.38 +/- 0.08 fs and tau 2H,perpendicular to =0.33 +/- 0.06 fs and for 1T-LixMoS2 as tau 1T,=0.32 +/- 0.12 fs and tau 1T,perpendicular to =0.09 +/- 0.07 fs. The isotropic charge delocalization of S3p electrons in the semiconducting 2H phase within the S-Mo-S sheets is assigned to the specific symmetry of the Mo-S bonding arrangement. Formation of 1T-LixMoS2 by lithiation accelerates the in-plane charge transfer by a factor of similar to 1.2 due to electron injection to the Mo-S covalent bonds and concomitant structural repositioning of S atoms within the S-Mo-S sheets. For excitation into out-of-plane orbitals, an accelerated charge transfer by a factor of similar to 3.7 upon lithiation occurs due to S-Li coupling.}, language = {en} } @article{Jakupec2017, author = {Jakupec, Viktor}, title = {Development Aid}, series = {Development Aid—Populism and the End of the Neoliberal Agenda}, journal = {Development Aid—Populism and the End of the Neoliberal Agenda}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-72748-6}, issn = {2211-4548}, doi = {10.1007/978-3-319-72748-6_2}, pages = {19 -- 36}, year = {2017}, abstract = {Development aid has been an important catalyst for economic development and international politics since the end of WWII. A critical analysis of the main political, social and economic advances in development aid, traces the development agenda from the advent of the Bretton Woods agreement, the Truman Doctrine and the Marshall Plan, to the Washington Consensus and its neoliberal manifesto. The failure of the Washington Consensus and the rise of the post-Washington Consensus is analysed providing a backdrop for the critique of economic globalisation as a development aid cornerstone. Trump's rejection of the neoliberal globalisation agenda and departure from post-WWII ideologies is discussed.}, language = {en} } @article{OeschWeiseBruno2020, author = {Oesch, Tyler and Weise, Frank and Bruno, Giovanni}, title = {Detection and quantification of cracking in concrete aggregate through virtual data fusion of X-ray computed tomography images}, series = {Materials}, volume = {13}, journal = {Materials}, number = {18}, publisher = {MDPI}, address = {Basel}, issn = {1996-1944}, doi = {10.3390/ma13183921}, pages = {27}, year = {2020}, abstract = {In this work, which is part of a larger research program, a framework called "virtual data fusion" was developed to provide an automated and consistent crack detection method that allows for the cross-comparison of results from large quantities of X-ray computed tomography (CT) data. A partial implementation of this method in a custom program was developed for use in research focused on crack quantification in alkali-silica reaction (ASR)-sensitive concrete aggregates. During the CT image processing, a series of image analyses tailored for detecting specific, individual crack-like characteristics were completed. The results of these analyses were then "fused" in order to identify crack-like objects within the images with much higher accuracy than that yielded by any individual image analysis procedure. The results of this strategy demonstrated the success of the program in effectively identifying crack-like structures and quantifying characteristics, such as surface area and volume. The results demonstrated that the source of aggregate has a very significant impact on the amount of internal cracking, even when the mineralogical characteristics remain very similar. River gravels, for instance, were found to contain significantly higher levels of internal cracking than quarried stone aggregates of the same mineralogical type.}, language = {en} } @misc{RadbruchPischonOstrowskietal.2017, author = {Radbruch, Moritz and Pischon, Hannah and Ostrowski, Anja and Volz, Pierre and Brodwolf, Robert and Neumann, Falko and Unbehauen, Michael and Kleuser, Burkhard and Haag, Rainer and Ma, Nan and Alexiev, Ulrike and Mundhenk, Lars and Gruber, Achim D.}, title = {Dendritic core-multishell nanocarriers in murine models of healthy and atopic skin}, series = {Postprints der Universit{\"a}t Potsdam Mathematisch-Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam Mathematisch-Naturwissenschaftliche Reihe}, number = {724}, issn = {1866-8372}, doi = {10.25932/publishup-43013}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-430136}, pages = {12}, year = {2017}, abstract = {Dendritic hPG-amid-C18-mPEG core-multishell nanocarriers (CMS) represent a novel class of unimolecular micelles that hold great potential as drug transporters, e. g., to facilitate topical therapy in skin diseases. Atopic dermatitis is among the most common inflammatory skin disorders with complex barrier alterations which may affect the efficacy of topical treatment. Here, we tested the penetration behavior and identified target structures of unloaded CMS after topical administration in healthy mice and in mice with oxazolone-induced atopic dermatitis. We further examined whole body distribution and possible systemic side effects after simulating high dosage dermal penetration by subcutaneous injection. Following topical administration, CMS accumulated in the stratum corneum without penetration into deeper viable epidermal layers. The same was observed in atopic dermatitis mice, indicating that barrier alterations in atopic dermatitis had no influence on the penetration of CMS. Following subcutaneous injection, CMS were deposited in the regional lymph nodes as well as in liver, spleen, lung, and kidney. However, in vitro toxicity tests, clinical data, and morphometry-assisted histopathological analyses yielded no evidence of any toxic or otherwise adverse local or systemic effects of CMS, nor did they affect the severity or course of atopic dermatitis. Taken together, CMS accumulate in the stratum corneum in both healthy and inflammatory skin and appear to be highly biocompatible in the mouse even under conditions of atopic dermatitis and thus could potentially serve to create a depot for anti-inflammatory drugs in the skin.}, language = {en} } @inproceedings{PanzerBenderGronau2021, author = {Panzer, Marcel and Bender, Benedict and Gronau, Norbert}, title = {Deep reinforcement learning in production planning and control}, series = {Proceedings of the Conference on Production Systems and Logistics}, booktitle = {Proceedings of the Conference on Production Systems and Logistics}, publisher = {publish-Ing.}, address = {Hannover}, issn = {2701-6277}, doi = {10.15488/11238}, pages = {535 -- 545}, year = {2021}, abstract = {Increasingly fast development cycles and individualized products pose major challenges for today's smart production systems in times of industry 4.0. The systems must be flexible and continuously adapt to changing conditions while still guaranteeing high throughputs and robustness against external disruptions. Deep rein- forcement learning (RL) algorithms, which already reached impressive success with Google DeepMind's AlphaGo, are increasingly transferred to production systems to meet related requirements. Unlike supervised and unsupervised machine learning techniques, deep RL algorithms learn based on recently collected sensor- and process-data in direct interaction with the environment and are able to perform decisions in real-time. As such, deep RL algorithms seem promising given their potential to provide decision support in complex environments, as production systems, and simultaneously adapt to changing circumstances. While different use-cases for deep RL emerged, a structured overview and integration of findings on their application are missing. To address this gap, this contribution provides a systematic literature review of existing deep RL applications in the field of production planning and control as well as production logistics. From a performance perspective, it became evident that deep RL can beat heuristics significantly in their overall performance and provides superior solutions to various industrial use-cases. Nevertheless, safety and reliability concerns must be overcome before the widespread use of deep RL is possible which presumes more intensive testing of deep RL in real world applications besides the already ongoing intensive simulations.}, language = {en} } @misc{PanzerBenderGronau2021, author = {Panzer, Marcel and Bender, Benedict and Gronau, Norbert}, title = {Deep reinforcement learning in production planning and control}, series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe}, journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe}, issn = {2701-6277}, doi = {10.25932/publishup-60572}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-605722}, pages = {13}, year = {2021}, abstract = {Increasingly fast development cycles and individualized products pose major challenges for today's smart production systems in times of industry 4.0. The systems must be flexible and continuously adapt to changing conditions while still guaranteeing high throughputs and robustness against external disruptions. Deep reinforcement learning (RL) algorithms, which already reached impressive success with Google DeepMind's AlphaGo, are increasingly transferred to production systems to meet related requirements. Unlike supervised and unsupervised machine learning techniques, deep RL algorithms learn based on recently collected sensorand process-data in direct interaction with the environment and are able to perform decisions in real-time. As such, deep RL algorithms seem promising given their potential to provide decision support in complex environments, as production systems, and simultaneously adapt to changing circumstances. While different use-cases for deep RL emerged, a structured overview and integration of findings on their application are missing. To address this gap, this contribution provides a systematic literature review of existing deep RL applications in the field of production planning and control as well as production logistics. From a performance perspective, it became evident that deep RL can beat heuristics significantly in their overall performance and provides superior solutions to various industrial use-cases. Nevertheless, safety and reliability concerns must be overcome before the widespread use of deep RL is possible which presumes more intensive testing of deep RL in real world applications besides the already ongoing intensive simulations.}, language = {en} } @misc{ShoaeeArminStolterfohtetal.2019, author = {Shoaee, Safa and Armin, Ardalan and Stolterfoht, Martin and Hosseini, Seyed Mehrdad and Kurpiers, Jona and Neher, Dieter}, title = {Decoding charge recombination through charge generation in organic solar cells}, series = {Postprints der Universit{\"a}t Potsdam Mathematisch-Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam Mathematisch-Naturwissenschaftliche Reihe}, number = {773}, issn = {1866-8372}, doi = {10.25932/publishup-43751}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-437512}, pages = {8}, year = {2019}, abstract = {The in-depth understanding of charge carrier photogeneration and recombination mechanisms in organic solar cells is still an ongoing effort. In donor:acceptor (bulk) heterojunction organic solar cells, charge photogeneration and recombination are inter-related via the kinetics of charge transfer states—being singlet or triplet states. Although high-charge-photogeneration quantum yields are achieved in many donor:acceptor systems, only very few systems show significantly reduced bimolecular recombination relative to the rate of free carrier encounters, in low-mobility systems. This is a serious limitation for the industrialization of organic solar cells, in particular when aiming at thick active layers. Herein, a meta-analysis of the device performance of numerous bulk heterojunction organic solar cells is presented for which field-dependent photogeneration, charge carrier mobility, and fill factor are determined. Herein, a "spin-related factor" that is dependent on the ratio of back electron transfer of the triplet charge transfer (CT) states to the decay rate of the singlet CT states is introduced. It is shown that this factor links the recombination reduction factor to charge-generation efficiency. As a consequence, it is only in the systems with very efficient charge generation and very fast CT dissociation that free carrier recombination is strongly suppressed, regardless of the spin-related factor.}, language = {en} } @article{GebserJanhunenRintanen2020, author = {Gebser, Martin and Janhunen, Tomi and Rintanen, Jussi}, title = {Declarative encodings of acyclicity properties}, series = {Journal of logic and computation}, volume = {30}, journal = {Journal of logic and computation}, number = {4}, publisher = {Oxford Univ. Press}, address = {Eynsham, Oxford}, issn = {0955-792X}, doi = {10.1093/logcom/exv063}, pages = {923 -- 952}, year = {2020}, abstract = {Many knowledge representation tasks involve trees or similar structures as abstract datatypes. However, devising compact and efficient declarative representations of such structural properties is non-obvious and can be challenging indeed. In this article, we take a number of acyclicity properties into consideration and investigate various logic-based approaches to encode them. We use answer set programming as the primary representation language but also consider mappings to related formalisms, such as propositional logic, difference logic and linear programming. We study the compactness of encodings and the resulting computational performance on benchmarks involving acyclic or tree structures.}, language = {en} } @misc{BeermannWestburyHofreiteretal.2018, author = {Beermann, Jan and Westbury, Michael V. and Hofreiter, Michael and Hilgers, Leon and Deister, Fabian and Neumann, Hermann and Raupach, Michael J.}, title = {Cryptic species in a well-known habitat}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe}, number = {1059}, issn = {1866-8372}, doi = {10.25932/publishup-46079}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-460792}, pages = {28}, year = {2018}, abstract = {Taxonomy plays a central role in biological sciences. It provides a communication system for scientists as it aims to enable correct identification of the studied organisms. As a consequence, species descriptions should seek to include as much available information as possible at species level to follow an integrative concept of 'taxonomics'. Here, we describe the cryptic species Epimeria frankei sp. nov. from the North Sea, and also redescribe its sister species, Epimeria cornigera. The morphological information obtained is substantiated by DNA barcodes and complete nuclear 18S rRNA gene sequences. In addition, we provide, for the first time, full mitochondrial genome data as part of a metazoan species description for a holotype, as well as the neotype. This study represents the first successful implementation of the recently proposed concept of taxonomics, using data from high-throughput technologies for integrative taxonomic studies, allowing the highest level of confidence for both biodiversity and ecological research.}, language = {en} } @misc{HeuerOrland2019, author = {Heuer, Leonie and Orland, Andreas}, title = {Cooperation in the Prisoner's Dilemma}, series = {Postprints der Universit{\"a}t Potsdam Wirtschafts- und Sozialwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam Wirtschafts- und Sozialwissenschaftliche Reihe}, number = {107}, issn = {1867-5808}, doi = {10.25932/publishup-43592}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-435929}, pages = {9}, year = {2019}, abstract = {Cooperation is — despite not being predicted by game theory — a widely documented aspect of human behaviour in Prisoner's Dilemma (PD) situations. This article presents a comparison between subjects restricted to playing pure strategies and subjects allowed to play mixed strategies in a one-shot symmetric PD laboratory experiment. Subjects interact with 10 other subjects and take their decisions all at once. Because subjects in the mixed-strategy treatment group are allowed to condition their level of cooperation more precisely on their beliefs about their counterparts' level of cooperation, we predicted the cooperation rate in the mixed-strategy treatment group to be higher than in the pure-strategy control group. The results of our experiment reject our prediction: even after controlling for beliefs about the other subjects' level of cooperation, we find that cooperation in the mixed-strategy group is lower than in the pure-strategy group. We also find, however, that subjects in the mixedstrategy group condition their cooperative behaviour more closely on their beliefs than in the pure-strategy group. In the mixed-strategy group, most subjects choose intermediate levels of cooperation.}, language = {en} } @article{HeuerOrland2019, author = {Heuer, Leonie and Orland, Andreas}, title = {Cooperation in the Prisoner's Dilemma}, series = {Royal Society Open Science}, volume = {6}, journal = {Royal Society Open Science}, publisher = {Royal Soc. Publ.}, address = {London}, issn = {2054-5703}, doi = {10.1098/rsos.182142}, pages = {9}, year = {2019}, abstract = {Cooperation is — despite not being predicted by game theory — a widely documented aspect of human behaviour in Prisoner's Dilemma (PD) situations. This article presents a comparison between subjects restricted to playing pure strategies and subjects allowed to play mixed strategies in a one-shot symmetric PD laboratory experiment. Subjects interact with 10 other subjects and take their decisions all at once. Because subjects in the mixed-strategy treatment group are allowed to condition their level of cooperation more precisely on their beliefs about their counterparts' level of cooperation, we predicted the cooperation rate in the mixed-strategy treatment group to be higher than in the pure-strategy control group. The results of our experiment reject our prediction: even after controlling for beliefs about the other subjects' level of cooperation, we find that cooperation in the mixed-strategy group is lower than in the pure-strategy group. We also find, however, that subjects in the mixedstrategy group condition their cooperative behaviour more closely on their beliefs than in the pure-strategy group. In the mixed-strategy group, most subjects choose intermediate levels of cooperation.}, language = {en} } @article{SoechtingTrapp2020, author = {S{\"o}chting, Maximilian and Trapp, Matthias}, title = {Controlling image-stylization techniques using eye tracking}, series = {Science and Technology Publications}, journal = {Science and Technology Publications}, publisher = {Springer}, address = {Berlin}, issn = {2184-4321}, pages = {10}, year = {2020}, abstract = {With the spread of smart phones capable of taking high-resolution photos and the development of high-speed mobile data infrastructure, digital visual media is becoming one of the most important forms of modern communication. With this development, however, also comes a devaluation of images as a media form with the focus becoming the frequency at which visual content is generated instead of the quality of the content. In this work, an interactive system using image-abstraction techniques and an eye tracking sensor is presented, which allows users to experience diverting and dynamic artworks that react to their eye movement. The underlying modular architecture enables a variety of different interaction techniques that share common design principles, making the interface as intuitive as possible. The resulting experience allows users to experience a game-like interaction in which they aim for a reward, the artwork, while being held under constraints, e.g., not blinking. The co nscious eye movements that are required by some interaction techniques hint an interesting, possible future extension for this work into the field of relaxation exercises and concentration training.}, language = {en} } @misc{SoechtingTrapp2020, author = {S{\"o}chting, Maximilian and Trapp, Matthias}, title = {Controlling image-stylization techniques using eye tracking}, series = {Postprints der Universit{\"a}t Potsdam : Reihe der Digital Engineering Fakult{\"a}t}, journal = {Postprints der Universit{\"a}t Potsdam : Reihe der Digital Engineering Fakult{\"a}t}, number = {7}, doi = {10.25932/publishup-52471}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-524717}, pages = {12}, year = {2020}, abstract = {With the spread of smart phones capable of taking high-resolution photos and the development of high-speed mobile data infrastructure, digital visual media is becoming one of the most important forms of modern communication. With this development, however, also comes a devaluation of images as a media form with the focus becoming the frequency at which visual content is generated instead of the quality of the content. In this work, an interactive system using image-abstraction techniques and an eye tracking sensor is presented, which allows users to experience diverting and dynamic artworks that react to their eye movement. The underlying modular architecture enables a variety of different interaction techniques that share common design principles, making the interface as intuitive as possible. The resulting experience allows users to experience a game-like interaction in which they aim for a reward, the artwork, while being held under constraints, e.g., not blinking. The co nscious eye movements that are required by some interaction techniques hint an interesting, possible future extension for this work into the field of relaxation exercises and concentration training.}, language = {en} } @phdthesis{Schneider2019, author = {Schneider, Jan Niklas}, title = {Computational approaches for emotion research}, doi = {10.25932/publishup-45927}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-459275}, school = {Universit{\"a}t Potsdam}, pages = {xv, 145}, year = {2019}, abstract = {Emotionen sind ein zentrales Element menschlichen Erlebens und spielen eine wichtige Rolle bei der Entscheidungsfindung. Diese Dissertation identifiziert drei methodische Probleme der aktuellen Emotionsforschung und zeigt auf, wie diese mittels computergest{\"u}tzter Methoden gel{\"o}st werden k{\"o}nnen. Dieser Ansatz wird in drei Forschungsprojekten demonstriert, die die Entwicklung solcher Methoden sowie deren Anwendung auf konkrete Forschungsfragen beschreiben. Das erste Projekt beschreibt ein Paradigma welches es erm{\"o}glicht, die subjektive und objektive Schwierigkeit der Emotionswahrnehmung zu messen. Dar{\"u}ber hinaus erm{\"o}glicht es die Verwendung einer beliebigen Anzahl von Emotionskategorien im Vergleich zu den {\"u}blichen sechs Kategorien der Basisemotionen. Die Ergebnisse deuten auf eine Zunahme der Schwierigkeiten bei der Wahrnehmung von Emotionen mit zunehmendem Alter der Darsteller hin und liefern Hinweise darauf, dass junge Erwachsene, {\"a}ltere Menschen und M{\"a}nner ihre Schwierigkeit bei der Wahrnehmung von Emotionen untersch{\"a}tzen. Weitere Analysen zeigten eine geringe Relevanz personenbezogener Variablen und deuteten darauf hin, dass die Schwierigkeit der Emotionswahrnehmung vornehmlich durch die Auspr{\"a}gung der Wertigkeit des Ausdrucks bestimmt wird. Das zweite Projekt zeigt am Beispiel von Arousal, einem etablierten, aber vagen Konstrukt der Emotionsforschung, wie Face-Tracking-Daten dazu genutzt werden k{\"o}nnen solche Konstrukte zu sch{\"a}rfen. Es beschreibt, wie aus Face-Tracking-Daten Maße f{\"u}r die Entfernung, Geschwindigkeit und Beschleunigung von Gesichtsausdr{\"u}cken berechnet werden k{\"o}nnen. Das Projekt untersuchte wie diesen Maße mit der Arousal-Wahrnehmung in Menschen mit und ohne Autismus zusammenh{\"a}ngen. Der Abstand zum Neutralgesicht war pr{\"a}diktiv f{\"u}r die Arousal-Bewertungen in beiden Gruppen. Die Ergebnisse deuten auf eine qualitativ {\"a}hnliche Wahrnehmung von Arousal f{\"u}r Menschen mit und ohne Autismus hin. Im dritten Projekt stellen wir die Partial-Least-Squares-Analyse als allgemeine Methode vor, um eine optimale Repr{\"a}sentation zur Verkn{\"u}pfung zweier hochdimensionale Datens{\"a}tze zu finden. Das Projekt demonstriert die Anwendbarkeit dieser Methode in der Emotionsforschung anhand der Frage nach Unterschieden in der Emotionswahrnehmung zwischen M{\"a}nnern und Frauen. Wir konnten zeigen, dass die emotionale Wahrnehmung von Frauen systematisch mehr Varianz der Gesichtsausdr{\"u}cke erfasst und dass signifikante Unterschiede in der Art und Weise bestehen, wie Frauen und M{\"a}nner einige Gesichtsausdr{\"u}cke wahrnehmen. Diese konnten wir als dynamische Gesichtsausdr{\"u}cke visualisieren. Um die Anwendung der entwickelten Methode f{\"u}r die Forschungsgemeinschaft zu erleichtern, wurde ein Software-Paket f{\"u}r die Statistikumgebung R geschrieben. Zudem wurde eine Website entwickelt (thisemotiondoesnotexist.com), die es Besuchern erlaubt, ein Partial-Least-Squares-Modell von Emotionsbewertungen und Face-Tracking-Daten interaktiv zu erkunden, um die entwickelte Methode zu verbreiten und ihren Nutzen f{\"u}r die Emotionsforschung zu illustrieren.}, language = {en} } @article{ZemellaThoringHoffmeisteretal.2018, author = {Zemella, Anne and Thoring, Lena and Hoffmeister, Christian and Samalikova, Maria and Ehren, Patricia and W{\"u}stenhagen, Doreen Anja and Kubick, Stefan}, title = {Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin}, series = {Scientific reports}, volume = {8}, journal = {Scientific reports}, publisher = {Nature Publ. Group}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-018-26936-x}, pages = {12}, year = {2018}, abstract = {As one of the most complex post-translational modification, glycosylation is widely involved in cell adhesion, cell proliferation and immune response. Nevertheless glycoproteins with an identical polypeptide backbone mostly differ in their glycosylation patterns. Due to this heterogeneity, the mapping of different glycosylation patterns to their associated function is nearly impossible. In the last years, glycoengineering tools including cell line engineering, chemoenzymatic remodeling and site-specific glycosylation have attracted increasing interest. The therapeutic hormone erythropoietin (EPO) has been investigated in particular by various groups to establish a production process resulting in a defined glycosylation pattern. However commercially available recombinant human EPO shows batch-to-batch variations in its glycoforms. Therefore we present an alternative method for the synthesis of active glycosylated EPO with an engineered O-glycosylation site by combining eukaryotic cell-free protein synthesis and site-directed incorporation of non-canonical amino acids with subsequent chemoselective modifications.}, language = {en} } @misc{ZemellaThoringHoffmeisteretal.2018, author = {Zemella, Anne and Thoring, Lena and Hoffmeister, Christian and Šamal{\´i}kov{\´a}, M{\´a}ria and Ehren, Patricia and W{\"u}stenhagen, Doreen Anja and Kubick, Stefan}, title = {Cell-free protein synthesis as a novel tool for directed glycoengineering of active erythropoietin}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch Naturwissenschaftliche Reihe}, number = {824}, doi = {10.25932/publishup-42701}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-427017}, pages = {14}, year = {2018}, abstract = {As one of the most complex post-translational modification, glycosylation is widely involved in cell adhesion, cell proliferation and immune response. Nevertheless glycoproteins with an identical polypeptide backbone mostly differ in their glycosylation patterns. Due to this heterogeneity, the mapping of different glycosylation patterns to their associated function is nearly impossible. In the last years, glycoengineering tools including cell line engineering, chemoenzymatic remodeling and site-specific glycosylation have attracted increasing interest. The therapeutic hormone erythropoietin (EPO) has been investigated in particular by various groups to establish a production process resulting in a defined glycosylation pattern. However commercially available recombinant human EPO shows batch-to-batch variations in its glycoforms. Therefore we present an alternative method for the synthesis of active glycosylated EPO with an engineered O-glycosylation site by combining eukaryotic cell-free protein synthesis and site-directed incorporation of non-canonical amino acids with subsequent chemoselective modifications.}, language = {en} }