@phdthesis{Prevot2006, author = {Prevot, Michelle Elizabeth}, title = {Introduction of a thermo-sensitive non-polar species into polyelectrolyte multilayer capsules for drug delivery}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-7785}, school = {Universit{\"a}t Potsdam}, year = {2006}, abstract = {The layer-by-layer assembly (LBL) of polyelectrolytes has been extensively studied for the preparation of ultrathin films due to the versatility of the build-up process. The control of the permeability of these layers is particularly important as there are potential drug delivery applications. Multilayered polyelectrolyte microcapsules are also of great interest due to their possible use as microcontainers. This work will present two methods that can be used as employable drug delivery systems, both of which can encapsulate an active molecule and tune the release properties of the active species. Poly-(N-isopropyl acrylamide), (PNIPAM) is known to be a thermo-sensitive polymer that has a Lower Critical Solution Temperature (LCST) around 32oC; above this temperature PNIPAM is insoluble in water and collapses. It is also known that with the addition of salt, the LCST decreases. This work shows Differential Scanning Calorimetry (DSC) and Confocal Laser Scanning Microscopy (CLSM) evidence that the LCST of the PNIPAM can be tuned with salt type and concentration. Microcapsules were used to encapsulate this thermo-sensitive polymer, resulting in a reversible and tunable stimuli- responsive system. The encapsulation of the PNIPAM inside of the capsule was proven with Raman spectroscopy, DSC (bulk LCST measurements), AFM (thickness change), SEM (morphology change) and CLSM (in situ LCST measurement inside of the capsules). The exploitation of the capsules as a microcontainer is advantageous not only because of the protection the capsules give to the active molecules, but also because it facilitates easier transport. The second system investigated demonstrates the ability to reduce the permeability of polyelectrolyte multilayer films by the addition of charged wax particles. The incorporation of this hydrophobic coating leads to a reduced water sensitivity particularly after heating, which melts the wax, forming a barrier layer. This conclusion was proven with Neutron Reflectivity by showing the decreased presence of D2O in planar polyelectrolyte films after annealing creating a barrier layer. The permeability of capsules could also be decreased by the addition of a wax layer. This was proved by the increase in recovery time measured by Florescence Recovery After Photobleaching, (FRAP) measurements. In general two advanced methods, potentially suitable for drug delivery systems, have been proposed. In both cases, if biocompatible elements are used to fabricate the capsule wall, these systems provide a stable method of encapsulating active molecules. Stable encapsulation coupled with the ability to tune the wall thickness gives the ability to control the release profile of the molecule of interest.}, subject = {Mikrokapsel}, language = {en} } @unpublished{Feudel1996, author = {Feudel, Ulrike}, title = {Komplexes Verhalten in multistabilen, schwach dissipativen Systemen}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-14412}, year = {1996}, abstract = {Anhand eines paradigmatischen Modellbeispiels werden die Konsequenzen der Koexistenz vieler Attraktoren auf die globale Dynamik schwach dissipativer Systeme studiert. Es wird gezeigt, dass diese Systeme eine sehr reichhaltige Dynamik besitzen und extrem sensitiv gegen{\"u}ber St{\"o}rungen in den Anfangsbedingungen sind. Diese Systeme zeichnen sich durch eine extrem hohe Flexibilit{\"a}t ihres Verhaltens aus.}, language = {de} } @unpublished{VolosevichMeister1998, author = {Volosevich, Alexandra V. and Meister, Claudia-Veronika}, title = {Nonlinear interaction of Farley-Buneman waves}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-14851}, year = {1998}, abstract = {The nonlinear interaction of waves excited by the modified two-stream instability (Farley-Buneman instability) is considered. It is found that, during the linear stage of wave growth, the enhanced pressure of the high-frequency part of the waves locally generates a ponderomotive force. This force acts on the plasma particles and redistributes them. Thus an additional electrostatic polarization field occurs, which influences the low-frequency part of the waves. Then, the low-frequency waves also cause a redistribution of the high-frequency waves. In the paper, a self-consistent system of equations is obtained, which describes the nonlinear interaction of the waves. It is shown that the considered mechanism of wave interaction causes a nonlinear stabilization of the high-frequency waves' growth and a formation of local density structures of the charged particles. The density modifications of the charged particles during the non-linear stage of wave growth and the possible interval of aspect angles of the high-frequency waves are estimated.}, language = {en} } @inproceedings{OPUS4-1412, title = {The 3rd international IEEE scientific conference on physics and control (PhysCon 2007) : September 3rd-7th 2007 at the University of Potsdam}, editor = {Kurths, J{\"u}rgen and Fradkov, Alexander and Chen, Guanrong}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-15228}, pages = {345}, year = {2007}, abstract = {During the last few years there was a tremendous growth of scientific activities in the fields related to both Physics and Control theory: nonlinear dynamics, micro- and nanotechnologies, self-organization and complexity, etc. New horizons were opened and new exciting applications emerged. Experts with different backgrounds starting to work together need more opportunities for information exchange to improve mutual understanding and cooperation. The Conference "Physics and Control 2007" is the third international conference focusing on the borderland between Physics and Control with emphasis on both theory and applications. With its 2007 address at Potsdam, Germany, the conference is located for the first time outside of Russia. The major goal of the Conference is to bring together researchers from different scientific communities and to gain some general and unified perspectives in the studies of controlled systems in physics, engineering, chemistry, biology and other natural sciences. We hope that the Conference helps experts in control theory to get acquainted with new interesting problems, and helps experts in physics and related fields to know more about ideas and tools from the modern control theory.}, language = {en} } @unpublished{BraunFeudelGuzdar1998, author = {Braun, Robert and Feudel, Fred and Guzdar, Parvez}, title = {The route to chaos for a two-dimensional externally driven flow}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-14717}, year = {1998}, abstract = {We have numerically studied the bifurcations and transition to chaos in a two-dimensional fluid for varying values of the Reynolds number. These investigations have been motivated by experiments in fluids, where an array of vortices was driven by an electromotive force. In these experiments, successive changes leading to a complex motion of the vortices, due to increased forcing, have been explored [Tabeling, Perrin, and Fauve, J. Fluid Mech. 213, 511 (1990)]. We model this experiment by means of two-dimensional Navier-Stokes equations with a special external forcing, driving a linear chain of eight counter-rotating vortices, imposing stress-free boundary conditions in the vertical direction and periodic boundary conditions in the horizontal direction. As the strength of the forcing or the Reynolds number is raised, the original stationary vortex array becomes unstable and a complex sequence of bifurcations is observed. Several steady states and periodic branches and a period doubling cascade appear on the route to chaos. For increasing values of the Reynolds number, shear flow develops, for which the spatial scale is large compared to the scale of the forcing. Furthermore, we have investigated the influence of the aspect ratio of the container as well as the effect of no-slip boundary conditions at the top and bottom, on the bifurcation scenario.}, language = {en} } @unpublished{Lukaschewitsch1998, author = {Lukaschewitsch, Michael}, title = {Geoelectrical conductivity problems on unbounded domains}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-14704}, year = {1998}, abstract = {This paper deals with the electrical conductivity problem in geophysics. It is formulated as an elliptic boundary value problem of second order for a large class of bounded and unbounded domains. A special boundary condition, the so called "Complete Electrode Model", is used. Poincar{\´e} inequalities are formulated and proved in the context of weighted Sobolev spaces, leading to existence and uniqueness statements for the boundary value problem. In addition, a parameter-to-solution operator arising from the inverse conductivity problem in medicine (EIT) and geophysics is investigated mathematically and is shown to be smooth and analytic.}, language = {en} } @unpublished{BoeckmannNiebsch1998, author = {B{\"o}ckmann, Christine and Niebsch, Jenny}, title = {Examination of the nonlinear LIDAR-operator : the influence of inhomogeneous absorbing spheres on the operator}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-14725}, year = {1998}, abstract = {The determination of the atmospheric aerosol size distribution is an inverse illposed problem. The shape and the material composition of the air-carried particles are two substantial model parameters. Present evaluation algorithms only used an approximation with spherical homogeneous particles. In this paper we propose a new numerically efficient recursive algorithm for inhomogeneous multilayered coated and absorbing particles. Numerical results of real existing particles show that the influence of the two parameters on the model is very important and therefore cannot be ignored.}, language = {en} } @unpublished{LiperovskyPochotelovLiperovskayaetal.1998, author = {Liperovsky, V.A. and Pochotelov, O.A. and Liperovskaya, E.V. and Parrot, M. and Meister, C.-V. and Alimov, O. A.}, title = {Modifications of sporadic E-layers caused by seismic activity}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-14799}, year = {1998}, abstract = {Contents: 1 Introduction 2 Formation and destruction of sporadic E-layers 3 Temporal variations of parameters of sporadic E-layers during earthquake preparation 3.1 Temporal variations of fbEs with time-scales of a few hours 3.2 Study of fbEs variations with characteristic time-scales of 0.5-3 hours 3.3 Variations of the parameters of sporadic E-layers with characteristic time-scales of 15-45 minutes 3.4 Sporadic E-layer variations with characteristic time-scales of 2-15 minutes 4 On the spatial scales of sporadic E-layer disturbances related to seismic activity 5 Complex experimental researches of the ionosphere, electromagnetic noise and the geomagnetic field 5.1 Ionospheric and electromagnetic phenomena of the Kayraccum earthquake in 1985 5.2 Comparison of anomalies with characteristic time-scales of 2-3 hours for ionospheric E- and F-layers, and temporal behaviour of electromagnetic noise emission intensity 5.3 Night airglow emissions in the E-region before earthquakes and sporadic E-layer variations 6 Physical models of lithosphere-ionosphere links 6.1 Lithosphere-ionosphere links due to AGW 6.2 Electromagnetic models for the lithosphere-ionosphere coupling 6.3 Sporadic E-layers as current generators 7 Discussion and conclusion}, language = {en} } @unpublished{WittNeimanKurths1997, author = {Witt, Annette and Neiman, Alexander and Kurths, J{\"u}rgen}, title = {Characterizing the dynamics of stochastic bistable systems by measures of complexity}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-14556}, year = {1997}, abstract = {The dynamics of noisy bistable systems is analyzed by means of Lyapunov exponents and measures of complexity. We consider both the classical Kramers problem with additive white noise and the case when the barrier fluctuates due to additional external colored noise. In case of additive noise we calculate the Lyapunov exponents and all measures of complexity analytically as functions of the noise intensity resp. the mean escape time. For the problem of fluctuating barrier the usual description of the dynamics with the mean escape time is not sufficient. The application of the concept of measures of complexity allows to describe the structures of motion in more detail. Most complexity measures sign the value of correlation time at which the phenomenon of resonant activation occurs with an extremum.}, language = {en} } @unpublished{BoeckmannBieleNeuberetal.1997, author = {B{\"o}ckmann, Christine and Biele, Jens and Neuber, Roland and Niebsch, Jenny}, title = {Retrieval of multimodal aerosol size distribution by inversion of multiwavelength data}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-14360}, year = {1997}, abstract = {The ill-posed problem of aerosol size distribution determination from a small number of backscatter and extinction measurements was solved successfully with a mollifier method which is advantageous since the ill-posed part is performed on exactly given quantities, the points r where n(r) is evaluated may be freely selected. A new twodimensional model for the troposphere is proposed.}, language = {en} }