@article{WoutersenJardineGiovanniBogotaAngeletal.2018,
  author    = {Woutersen, Amber and Jardine, Phillip E. and Giovanni Bogota-Angel, Raul and Zhang, Hong-Xiang and Silvestro, Daniele and Antonelli, Alexandre and Gogna, Elena and Erkens, Roy H. J. and Gosling, William D. and Dupont-Nivet, Guillaume and Hoorn, Carina},
  title     = {A novel approach to study the morphology and chemistry of pollen in a phylogenetic context, applied to the halophytic taxon Nitraria L.(Nitrariaceae)},
  series = {PeerJ},
  volume    = {6},
  journal   = {PeerJ},
  publisher = {PeerJ Inc.},
  address   = {London},
  issn      = {2167-8359},
  doi       = {10.7717/peerj.5055},
  pages     = {31},
  year      = {2018},
  abstract  = {Nitraria is a halophytic taxon (i.e., adapted to saline environments) that belongs to the plant family Nitrariaceae and is distributed from the Mediterranean, across Asia into the south-eastern tip of Australia. This taxon is thought to have originated in Asia during the Paleogene (66-23 Ma), alongside the proto-Paratethys epicontinental sea. The evolutionary history of Nitraria might hold important clues on the links between climatic and biotic evolution but limited taxonomic documentation of this taxon has thus far hindered this line of research. Here we investigate if the pollen morphology and the chemical composition of the pollen wall are informative of the evolutionary history of Nitraria and could explain if origination along the proto-Paratethys and dispersal to the Tibetan Plateau was simultaneous or a secondary process. To answer these questions, we applied a novel approach consisting of a combination of Fourier Transform Infrared spectroscopy (FTIR), to determine the chemical composition of the pollen wall, and pollen morphological analyses using Light Microscopy (LM) and Scanning Electron Microscopy (SEM). We analysed our data using ordinations (principal components analysis and non-metric multidimensional scaling), and directly mapped it on the Nitrariaceae phylogeny to produce a phylomorphospace and a phylochemospace. Our LM, SEM and FTIR analyses show clear morphological and chemical differences between the sister groups Peganum and Nitraria. Differences in the morphological and chemical characteristics of highland species (Nitraria schoberi, N. sphaerocarpa, N. sibirica and N. tangutorum) and lowland species (Nitraria billardierei and N. retusa) are very subtle, with phylogenetic history appearing to be a more important control on Nitraria pollen than local environmental conditions. Our approach shows a compelling consistency between the chemical and morphological characteristics of the eight studied Nitrariaceae species, and these traits are in agreement with the phylogenetic tree. Taken together, this demonstrates how novel methods for studying fossil pollen can facilitate the evolutionary investigation of living and extinct taxa, and the environments they represent.},
  language  = {en}
}
@article{VaidSomaniRussaketal.2020,
  author    = {Vaid, Akhil and Somani, Sulaiman and Russak, Adam J. and De Freitas, Jessica K. and Chaudhry, Fayzan F. and Paranjpe, Ishan and Johnson, Kipp W. and Lee, Samuel J. and Miotto, Riccardo and Richter, Felix and Zhao, Shan and Beckmann, Noam D. and Naik, Nidhi and Kia, Arash and Timsina, Prem and Lala, Anuradha and Paranjpe, Manish and Golden, Eddye and Danieletto, Matteo and Singh, Manbir and Meyer, Dara and O'Reilly, Paul F. and Huckins, Laura and Kovatch, Patricia and Finkelstein, Joseph and Freeman, Robert M. and Argulian, Edgar and Kasarskis, Andrew and Percha, Bethany and Aberg, Judith A. and Bagiella, Emilia and Horowitz, Carol R. and Murphy, Barbara and Nestler, Eric J. and Schadt, Eric E. and Cho, Judy H. and Cordon-Cardo, Carlos and Fuster, Valentin and Charney, Dennis S. and Reich, David L. and B{\"o}ttinger, Erwin and Levin, Matthew A. and Narula, Jagat and Fayad, Zahi A. and Just, Allan C. and Charney, Alexander W. and Nadkarni, Girish N. and Glicksberg, Benjamin S.},
  title     = {Machine learning to predict mortality and critical events in a cohort of patients with COVID-19 in New York City: model development and validation},
  series = {Journal of medical internet research : international scientific journal for medical research, information and communication on the internet ; JMIR},
  volume    = {22},
  journal   = {Journal of medical internet research : international scientific journal for medical research, information and communication on the internet ; JMIR},
  number    = {11},
  publisher = {Healthcare World},
  address   = {Richmond, Va.},
  issn      = {1439-4456},
  doi       = {10.2196/24018},
  pages     = {19},
  year      = {2020},
  abstract  = {Background: COVID-19 has infected millions of people worldwide and is responsible for several hundred thousand fatalities. The COVID-19 pandemic has necessitated thoughtful resource allocation and early identification of high-risk patients. However, effective methods to meet these needs are lacking. Objective: The aims of this study were to analyze the electronic health records (EHRs) of patients who tested positive for COVID-19 and were admitted to hospitals in the Mount Sinai Health System in New York City; to develop machine learning models for making predictions about the hospital course of the patients over clinically meaningful time horizons based on patient characteristics at admission; and to assess the performance of these models at multiple hospitals and time points. Methods: We used Extreme Gradient Boosting (XGBoost) and baseline comparator models to predict in-hospital mortality and critical events at time windows of 3, 5, 7, and 10 days from admission. Our study population included harmonized EHR data from five hospitals in New York City for 4098 COVID-19-positive patients admitted from March 15 to May 22, 2020. The models were first trained on patients from a single hospital (n=1514) before or on May 1, externally validated on patients from four other hospitals (n=2201) before or on May 1, and prospectively validated on all patients after May 1 (n=383). Finally, we established model interpretability to identify and rank variables that drive model predictions. Results: Upon cross-validation, the XGBoost classifier outperformed baseline models, with an area under the receiver operating characteristic curve (AUC-ROC) for mortality of 0.89 at 3 days, 0.85 at 5 and 7 days, and 0.84 at 10 days. XGBoost also performed well for critical event prediction, with an AUC-ROC of 0.80 at 3 days, 0.79 at 5 days, 0.80 at 7 days, and 0.81 at 10 days. In external validation, XGBoost achieved an AUC-ROC of 0.88 at 3 days, 0.86 at 5 days, 0.86 at 7 days, and 0.84 at 10 days for mortality prediction. Similarly, the unimputed XGBoost model achieved an AUC-ROC of 0.78 at 3 days, 0.79 at 5 days, 0.80 at 7 days, and 0.81 at 10 days. Trends in performance on prospective validation sets were similar. At 7 days, acute kidney injury on admission, elevated LDH, tachypnea, and hyperglycemia were the strongest drivers of critical event prediction, while higher age, anion gap, and C-reactive protein were the strongest drivers of mortality prediction. Conclusions: We externally and prospectively trained and validated machine learning models for mortality and critical events for patients with COVID-19 at different time horizons. These models identified at-risk patients and uncovered underlying relationships that predicted outcomes.},
  language  = {en}
}
@article{DoellDjalaliFarahaniKofoetZrenneretal.2021,
  author    = {D{\"o}ll, Stefanie and Djalali Farahani-Kofoet, Roxana and Zrenner, Rita and Henze, Andrea and Witzel, Katja},
  title     = {Tissue-specific signatures of metabolites and proteins in asparagus roots and exudates},
  series = {Horticulture research},
  volume    = {8},
  journal   = {Horticulture research},
  number    = {1},
  publisher = {Nanjing Agricultural Univ.},
  address   = {Nanjing},
  issn      = {2052-7276},
  doi       = {10.1038/s41438-021-00510-5},
  pages     = {14},
  year      = {2021},
  abstract  = {Comprehensive untargeted and targeted analysis of root exudate composition has advanced our understanding of rhizosphere processes. However, little is known about exudate spatial distribution and regulation. We studied the specific metabolite signatures of asparagus root exudates, root outer (epidermis and exodermis), and root inner tissues (cortex and vasculature). The greatest differences were found between exudates and root tissues. In total, 263 non-redundant metabolites were identified as significantly differentially abundant between the three root fractions, with the majority being enriched in the root exudate and/or outer tissue and annotated as 'lipids and lipid-like molecules' or 'phenylpropanoids and polyketides'. Spatial distribution was verified for three selected compounds using MALDI-TOF mass spectrometry imaging. Tissue-specific proteome analysis related root tissue-specific metabolite distributions and rhizodeposition with underlying biosynthetic pathways and transport mechanisms. The proteomes of root outer and inner tissues were spatially very distinct, in agreement with the fundamental differences between their functions and structures. According to KEGG pathway analysis, the outer tissue proteome was characterized by a high abundance of proteins related to 'lipid metabolism', 'biosynthesis of other secondary metabolites' and 'transport and catabolism', reflecting its main functions of providing a hydrophobic barrier, secreting secondary metabolites, and mediating water and nutrient uptake. Proteins more abundant in the inner tissue related to 'transcription', 'translation' and 'folding, sorting and degradation', in accord with the high activity of cortical and vasculature cell layers in growth- and development-related processes. In summary, asparagus root fractions accumulate specific metabolites. This expands our knowledge of tissue-specific plant cell function.},
  language  = {en}
}
@article{KapidzicFreyNeubergeretal.2023,
  author    = {Kapidzic, Sanja and Frey, Felix and Neuberger, Christoph and Stieglitz, Stefan and Mirbabaie, Milad},
  title     = {Crisis communication on Twitter},
  series = {International journal of communication},
  volume    = {17},
  journal   = {International journal of communication},
  publisher = {The Annenberg Center for Communication},
  address   = {Los Angeles, Calif.},
  issn      = {1932-8036},
  pages     = {735 -- 754},
  year      = {2023},
  abstract  = {The study explores differences between three user types in the top tweets about the 2015 "refugee crisis" in Germany and presents the results of a quantitative content analysis. All tweets with the keyword "Fl{\"u}chtlinge" posted for a monthlong period following September 13, 2015, the day Germany decided to implement border controls, were collected (N = 763,752). The top 2,495 tweets according to number of retweets were selected for analysis. Differences between news media, public and private actor tweets in topics, tweet characteristics such as tone and opinion expression, links, and specific sentiments toward refugees were analyzed. We found strong differences between the tweets. Public actor tweets were the main source of positive sentiment toward refugees and the main information source on refugee support. News media tweets mostly reflected traditional journalistic norms of impartiality and objectivity, whereas private actor tweets were more diverse in sentiments toward refugees.},
  language  = {en}
}
@article{ToumoulinTardifBecquetDonnadieuetal.2022,
  author    = {Toumoulin, Agathe and Tardif-Becquet, Delphine and Donnadieu, Yannick and Licht, Alexis and Ladant, Jean-Baptiste and Kunzmann, Lutz and Dupont-Nivet, Guillaume},
  title     = {Evolution of continental temperature seasonality from the Eocene greenhouse to the Oligocene icehouse},
  series = {Climate of the past : an interactive open access journal of the European Geosciences Union},
  volume    = {18},
  journal   = {Climate of the past : an interactive open access journal of the European Geosciences Union},
  number    = {2},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1814-9324},
  doi       = {10.5194/cp-18-341-2022},
  pages     = {341 -- 362},
  year      = {2022},
  abstract  = {At the junction of greenhouse and icehouse climate states, the Eocene-Oligocene Transition (EOT) is a key moment in Cenozoic climate history. While it is associated with severe extinctions and biodiversity turnovers on land, the role of terrestrial climate evolution remains poorly resolved, especially the associated changes in seasonality. Some paleobotanical and geochemical continental records in parts of the Northern Hemisphere suggest the EOT is associated with a marked cooling in winter, leading to the development of more pronounced seasons (i.e., an increase in the mean annual range of temperature, MATR). However, the MATR increase has been barely studied by climate models and large uncertainties remain on its origin, geographical extent and impact. In order to better understand and describe temperature seasonality changes between the middle Eocene and the early Oligocene, we use the Earth system model IPSL-CM5A2 and a set of simulations reconstructing the EOT through three major climate forcings: pCO(2) decrease (1120, 840 and 560 ppm), the Antarctic ice-sheet (AIS) formation and the associated sea-level decrease. Our simulations suggest that pCO(2) lowering alone is not sufficient to explain the seasonality evolution described by the data through the EOT but rather that the combined effects of pCO(2) , AIS formation and increased continentality provide the best data-model agreement.pCO(2) decrease induces a zonal pattern with alternating increasing and decreasing seasonality bands particularly strong in the northern high latitudes (up to 8 degrees C MATR increase) due to sea-ice and surface albedo feedback. Conversely, the onset of the AIS is responsible for a more constant surface albedo yearly, which leads to a strong decrease in seasonality in the southern midlatitudes to high latitudes (> 40 degrees S). Finally, continental areas that emerged due to the sea-level lowering cause the largest increase in seasonality and explain most of the global heterogeneity in MATR changes (1MATR) patterns. The Delta MATR patterns we reconstruct are generally consistent with the variability of the EOT biotic crisis intensity across the Northern Hemisphere and provide insights on their underlying mechanisms.},
  language  = {en}
}
@article{TardifBecquetFluteauDonnadieuetal.2020,
  author    = {Tardif-Becquet, Delphine and Fluteau, Fr{\´e}d{\´e}ric and Donnadieu, Yannick and Le Hir, Guillaume and Ladant, Jean-Baptiste and Sepulchre, Pierre and Licht, Alexis and Poblete, Fernando and Dupont-Nivet, Guillaume},
  title     = {The origin of Asian monsoons},
  series = {Climate of the Past},
  volume    = {16},
  journal   = {Climate of the Past},
  number    = {3},
  publisher = {Copernicus Publications},
  address   = {G{\"o}ttingen},
  issn      = {1814-9332},
  doi       = {10.5194/cp-16-847-2020},
  pages     = {847 -- 865},
  year      = {2020},
  abstract  = {The Cenozoic inception and development of the Asian monsoons remain unclear and have generated much debate, as several hypotheses regarding circulation patterns at work in Asia during the Eocene have been proposed in the few last decades. These include (a) the existence of modern-like monsoons since the early Eocene; (b) that of a weak South Asian monsoon (SAM) and little to no East Asian monsoon (EAM); or (c) a prevalence of the Intertropical Convergence Zone (ITCZ) migrations, also referred to as Indonesian-Australian monsoon (I-AM). As SAM and EAM are supposed to have been triggered or enhanced primarily by Asian palaeogeographic changes, their possible inception in the very dynamic Eocene palaeogeographic context remains an open question, both in the modelling and field-based communities. We investigate here Eocene Asian climate conditions using the IPSL-CM5A2 (Sepulchre et al., 2019) earth system model and revised palaeogeographies. Our Eocene climate simulation yields atmospheric circulation patterns in Asia substantially different from modern conditions. A large high-pressure area is simulated over the Tethys ocean, which generates intense low tropospheric winds blowing southward along the western flank of the proto-Himalayan-Tibetan plateau (HTP) system. This low-level wind system blocks, to latitudes lower than 10 degrees N, the migration of humid and warm air masses coming from the Indian Ocean. This strongly contrasts with the modern SAM, during which equatorial air masses reach a latitude of 20-25 degrees N over India and southeastern China. Another specific feature of our Eocene simulation is the widespread subsidence taking place over northern India in the midtroposphere (around 5000 m), preventing deep convective updraught that would transport water vapour up to the condensation level. Both processes lead to the onset of a broad arid region located over northern India and over the HTP. More humid regions of high seasonality in precipitation encircle this arid area, due to the prevalence of the Intertropical Convergence Zone (ITCZ) migrations (or Indonesian-Australian monsoon, I-AM) rather than monsoons. Although the existence of this central arid region may partly result from the specifics of our simulation (model dependence and palaeogeographic uncertainties) and has yet to be confirmed by proxy records, most of the observational evidence for Eocene monsoons are located in the highly seasonal transition zone between the arid area and the more humid surroundings. We thus suggest that a zonal arid climate prevailed over Asia before the initiation of monsoons that most likely occurred following Eocene palaeogeographic changes. Our results also show that precipitation seasonality should be used with caution to infer the presence of a monsoonal circulation and that the collection of new data in this arid area is of paramount importance to allow the debate to move forward.},
  language  = {en}
}
@article{KoenigBlockBeckeretal.2018,
  author    = {K{\"o}nig, Johanna and Block, Andrea and Becker, Mathias and Fenske, Kristin and Hertel, Johannes and Van der Auwera, Sandra and Zymara, Kathleen and Voelzke, Henry and Freyberger, Harald J{\"u}rgen and Grabe, Hans Joergen},
  title     = {Assessment of subjective emotional valence and long-lasting impact of life events},
  series = {BMC Psychiatry},
  volume    = {18},
  journal   = {BMC Psychiatry},
  publisher = {BioMed Central},
  address   = {London},
  issn      = {1471-244X},
  doi       = {10.1186/s12888-018-1649-3},
  pages     = {12},
  year      = {2018},
  abstract  = {Background: Life events (LEs) are associated with future physical and mental health. They are crucial for understanding the pathways to mental disorders as well as the interactions with biological parameters. However, deeper insight is needed into the complex interplay between the type of LE, its subjective evaluation and accompanying factors such as social support. The "Stralsund Life Event List" (SEL) was developed to facilitate this research. Methods: The SEL is a standardized interview that assesses the time of occurrence and frequency of 81 LEs, their subjective emotional valence, the perceived social support during the LE experience and the impact of past LEs on present life. Data from 2265 subjects from the general population-based cohort study "Study of Health in Pomerania" (SHIP) were analysed. Based on the mean emotional valence ratings of the whole sample, LEs were categorized as "positive" or "negative". For verification, the SEL was related to lifetime major depressive disorder (MDD; Munich Composite International Diagnostic Interview), childhood trauma (Childhood Trauma Questionnaire), resilience (Resilience Scale) and subjective health (SF-12 Health Survey). Conclusions: The SEL is a valid instrument that enables the analysis of the number and frequency of LEs, their emotional valence, perceived social support and current impact on life on a global score and on an individual item level. Thus, we can recommend its use in research settings that require the assessment and analysis of the relationship between the occurrence and subjective evaluation of LEs as well as the complex balance between distressing and stabilizing life experiences.},
  language  = {en}
}
@article{HerrmannBodenMaureretal.2022,
  author    = {Herrmann, Matthias L. and Boden, Cindy and Maurer, Christoph and Kentischer, Felix and Mennig, Eva and Wagner, S{\"o}ren and Conzelmann, Lars O. and F{\"o}rstner, Bernd R. and Rapp, Michael A. and von Arnim, Christine A. F. and Denkinger, Michael and Eschweiler, Gerhard W. and Thomas, Christine},
  title     = {Anticholinergic drug exposure increases the risk of delirium in older patients undergoing elective surgery},
  series = {Frontiers in medicine},
  volume    = {9},
  journal   = {Frontiers in medicine},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-858X},
  doi       = {10.3389/fmed.2022.871229},
  pages     = {8},
  year      = {2022},
  abstract  = {IntroductionPostoperative delirium (POD) is a common and serious adverse event of surgery in older people. Because of its great impact on patients' safety and quality of life, identification of modifiable risk factors could be useful. Although preoperative medication intake is assumed to be an important modifiable risk factor, the impact of anticholinergic drugs on the occurrence of POD seems underestimated in elective surgery. The aim of this study was to investigate the association between preoperative anticholinergic burden and POD. We hypothesized that a high preoperative anticholinergic burden is an independent, potentially modifiable predisposing and precipitating factor of POD in older people. MethodsBetween November 2017 and April 2019, 1,470 patients of 70 years and older undergoing elective orthopedic, general, cardiac, or vascular surgery were recruited in the randomized, prospective, multicenter PAWEL trial. Anticholinergic burden of a sub-cohort of 899 patients, who did not receive a multimodal intervention for preventing POD, was assessed by two different tools at hospital admission: The established Anticholinergic Risk Scale (ARS) and the recently developed Anticholinergic Burden Score (ABS). POD was detected by confusion assessment method (CAM) and a validated post discharge medical record review. Logistic regression analyses were performed to evaluate the association between anticholinergic burden and POD. ResultsPOD was observed in 210 of 899 patients (23.4\%). Both ARS and ABS were independently associated with POD. The association persisted after adjustment for relevant confounding factors such as age, sex, comorbidities, preoperative cognitive and physical status, number of prescribed drugs, surgery time, type of surgery and anesthesia, usage of heart-lung-machine, and treatment in intensive care unit. If a patient was taking one of the 56 drugs listed in the ABS, risk for POD was 2.7-fold higher (OR = 2.74, 95\% CI = 1.55-4.94) and 1.5-fold higher per additional point on the ARS (OR = 1.54, 95\% CI = 1.15-2.02). ConclusionPreoperative anticholinergic drug exposure measured by ARS or ABS was independently associated with POD in older patients undergoing elective surgery. Therefore, identification, discontinuation or substitution of anticholinergic medication prior to surgery may be a promising approach to reduce the risk of POD in older patients.},
  language  = {en}
}
@article{JaraMunozMelnickLietal.2022,
  author    = {Jara-Mu{\~n}oz, Julius and Melnick, Daniel and Li, Shaoyang and Socquet, Anne and Cort{\´e}s-Aranda, Joaqu{\´i}n and Brill, Dominik and Strecker, Manfred R.},
  title     = {The cryptic seismic potential of the Pichilemu blind fault in Chile revealed by off-fault geomorphology},
  series = {Nature communications},
  volume    = {13},
  journal   = {Nature communications},
  number    = {1},
  publisher = {Nature Research},
  address   = {Berlin},
  issn      = {2041-1723},
  doi       = {10.1038/s41467-022-30754-1},
  pages     = {13},
  year      = {2022},
  abstract  = {The first step towards assessing hazards in seismically active regions involves mapping capable faults and estimating their recurrence times. While the mapping of active faults is commonly based on distinct geologic and geomorphic features evident at the surface, mapping blind seismogenic faults is complicated by the absence of on-fault diagnostic features. Here we investigated the Pichilemu Fault in coastal Chile, unknown until it generated a Mw 7.0 earthquake in 2010. The lack of evident surface faulting suggests activity along a partly-hidden blind fault. We used off-fault deformed marine terraces to estimate a fault-slip rate of 0.52 +/- 0.04 m/ka, which, when integrated with satellite geodesy suggests a 2.12 +/- 0.2 ka recurrence time for Mw similar to 7.0 normal-faulting earthquakes. We propose that extension in the Pichilemu region is associated with stress changes during megathrust earthquakes and accommodated by sporadic slip during upper-plate earthquakes, which has implications for assessing the seismic potential of cryptic faults along convergent margins and elsewhere.},
  language  = {en}
}
@article{HaugkJongejansMangelsdorfetal.2022,
  author    = {Haugk, Charlotte and Jongejans, Loeka L. and Mangelsdorf, Kai and Fuchs, Matthias and Ogneva, Olga and Palmtag, Juri and Mollenhauer, Gesine and Mann, Paul J. and Overduin, P. Paul and Grosse, Guido and Sanders, Tina and Tuerena, Robyn E. and Schirrmeister, Lutz and Wetterich, Sebastian and Kizyakov, Alexander and Karger, Cornelia and Strauss, Jens},
  title     = {Organic matter characteristics of a rapidly eroding permafrost cliff in NE Siberia (Lena Delta, Laptev Sea region)},
  series = {Biogeosciences},
  volume    = {19},
  journal   = {Biogeosciences},
  number    = {7},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1726-4170},
  doi       = {10.5194/bg-19-2079-2022},
  pages     = {2079 -- 2094},
  year      = {2022},
  abstract  = {Organic carbon (OC) stored in Arctic permafrost represents one of Earth's largest and most vulnerable terrestrial carbon pools. Amplified climate warming across the Arctic results in widespread permafrost thaw. Permafrost deposits exposed at river cliffs and coasts are particularly susceptible to thawing processes. Accelerating erosion of terrestrial permafrost along shorelines leads to increased transfer of organic matter (OM) to nearshore waters. However, the amount of terrestrial permafrost carbon and nitrogen as well as the OM quality in these deposits is still poorly quantified. We define the OM quality as the intrinsic potential for further transformation, decomposition and mineralisation. Here, we characterise the sources and the quality of OM supplied to the Lena River at a rapidly eroding permafrost river shoreline cliff in the eastern part of the delta (Sobo-Sise Island). Our multi-proxy approach captures bulk elemental, molecu- lar geochemical and carbon isotopic analyses of Late Pleistocene Yedoma permafrost and Holocene cover deposits, discontinuously spanning the last similar to 52 kyr. We showed that the ancient permafrost exposed in the Sobo-Sise cliff has a high organic carbon content (mean of about 5 wt \%). The oldest sediments stem from Marine Isotope Stage (MIS) 3 interstadial deposits (dated to 52 to 28 cal ka BP) and are overlaid by last glacial MIS 2 (dated to 28 to 15 cal ka BP) and Holocene MIS 1 (dated to 7-0 cal ka BP) deposits. The relatively high average chain length (ACL) index of n-alkanes along the cliff profile indicates a predominant contribution of vascular plants to the OM composition. The elevated ratio of isoand anteiso-branched fatty acids (FAs) relative to mid- and long-chain (C >= 20) n-FAs in the interstadial MIS 3 and the interglacial MIS 1 deposits suggests stronger microbial activity and consequently higher input of bacterial biomass during these climatically warmer periods. The overall high carbon preference index (CPI) and higher plant fatty acid (HPFA) values as well as high C/N ratios point to a good quality of the preserved OM and thus to a high potential of the OM for decomposition upon thaw. A decrease in HPFA values downwards along the profile probably indicates stronger OM decomposition in the oldest (MIS 3) deposits of the cliff. The characterisation of OM from eroding permafrost leads to a better assessment of the greenhouse gas potential of the OC released into river and nearshore waters in the future.},
  language  = {en}
}
@article{VoglimacciStephanopoliWendlederLantuitetal.2022,
  author    = {Voglimacci-Stephanopoli, Jo{\"e}lle and Wendleder, Anna and Lantuit, Hugues and Langlois, Alexandre and Stettner, Samuel and Schmitt, Andreas and Dedieu, Jean-Pierre and Roth, Achim and Royer, Alain},
  title     = {Potential of X-band polarimetric synthetic aperture radar co-polar phase difference for arctic snow depth estimation},
  series = {Cryosphere},
  volume    = {16},
  journal   = {Cryosphere},
  number    = {6},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-16-2163-2022},
  pages     = {2163 -- 2181},
  year      = {2022},
  abstract  = {Changes in snowpack associated with climatic warming has drastic impacts on surface energy balance in the cryosphere. Yet, traditional monitoring techniques, such as punctual measurements in the field, do not cover the full snowpack spatial and temporal variability, which hampers efforts to upscale measurements to the global scale. This variability is one of the primary constraints in model development. In terms of spatial resolution, active microwaves (synthetic aperture radar - SAR) can address the issue and outperform methods based on passive microwaves. Thus, high-spatial-resolution monitoring of snow depth (SD) would allow for better parameterization of local processes that drive the spatial variability of snow. The overall objective of this study is to evaluate the potential of the TerraSAR-X (TSX) SAR sensor and the wave co-polar phase difference (CPD) method for characterizing snow cover at high spatial resolution. Consequently, we first (1) investigate SD and depth hoar fraction (DHF) variability between different vegetation classes in the Ice Creek catchment (Qikiqtaruk/Herschel Island, Yukon, Canada) using in situ measurements collected over the course of a field campaign in 2019; (2) evaluate linkages between snow characteristics and CPD distribution over the 2019 dataset; and (3) determine CPD seasonality considering meteorological data over the 2015-2019 period. SD could be extracted using the CPD when certain conditions are met. A high incidence angle (>30 circle) with a high topographic wetness index (TWI) (>7.0) showed correlation between SD and CPD (R2 up to 0.72). Further, future work should address a threshold of sensitivity to TWI and incidence angle to map snow depth in such environments and assess the potential of using interpolation tools to fill in gaps in SD information on drier vegetation types.},
  language  = {en}
}
@article{ZechSchuchPerezChaparroetal.2020,
  author    = {Zech, Philipp and Schuch, Felipe and P{\´e}rez Chaparro, Camilo Germ{\´a}n Alberto and Kangas, Maria and Rapp, Michael A. and Heissel, Andreas},
  title     = {Exercise, Comorbidities, and Health-Related Quality of Life in People Living with HIV},
  series = {International Journal of Environmental Research and Public Health},
  volume    = {17},
  journal   = {International Journal of Environmental Research and Public Health},
  number    = {14},
  publisher = {MDPI AG},
  address   = {Basel},
  issn      = {1660-4601},
  doi       = {10.3390/ijerph17145138},
  pages     = {15},
  year      = {2020},
  abstract  = {(1) Background: People with HIV (PWH) may perform more than one type of exercise cumulatively. The objective of this study is to investigate recreational exercise and its association with health-related quality of life (HRQOL) and comorbidities in relation to potential covariates. (2) Methods: The HIBES study (HIV-Begleiterkrankungen-Sport) is a cross-sectional study for people with HIV. The differences between non-exercisers versus exercisers (cumulated vs. single type of exercises) were investigated using regression models based on 454 participants. (3) Results: Exercisers showed a higher HRQOL score compared to non-exercisers (Wilcox r = 0.2 to 0.239). Psychological disorders were identified as the main covariate. Participants performing exercise cumulatively showed higher scores in duration, frequency, and intensity when compared to participants performing only one type of exercise. The mental health summary score was higher for the cumulated and single type of exercise if a psychological disorder existed. Duration and intensity were associated with an increase of HRQOL, whilst a stronger association between psychological disorders and exercise variables were evident. Exercise duration (minutes) showed a significant effect on QOL (standardized beta = 0.1) and for participants with psychological disorders (standardized beta = 0.3), respectively. (4) Conclusions: Psychological disorders and other covariates have a prominent effect on HRQOL and its association with exercise. For PWH with a psychological disorder, a stronger relationship between HRQOL with exercise duration and intensity emerged. However, differentiation of high-HRQOL individuals warrants further investigation by considering additional factors.},
  language  = {en}
}
@article{DeekenReichertZechetal.2022,
  author    = {Deeken, Friederike and Reichert, Markus and Zech, Hilmar and Wenzel, Julia and Wedemeyer, Friederike and Aguilera, Alvaro and Aslan, Acelya and Bach, Patrick and Bahr, Nadja Samia and Ebrahimi, Claudia and Fischbach, Pascale Christine and Ganz, Marvin and Garbusow, Maria and Großkopf, Charlotte M. and Heigert, Marie and Hentschel, Angela and Karl, Damian and Pelz, Patricia and Pinger, Mathieu and Riemerschmid, Carlotta and Rosenthal, Annika and Steffen, Johannes and Strehle, Jens and Weiss,, Franziska and Wieder, Gesine and Wieland, Alfred and Zaiser, Judith and Zimmermann, Sina and Walter, Henrik and Lenz, Bernd and Deserno, Lorenz and Smolka, Michael N. and Liu, Shuyan and Ebner-Priemer, Ulrich Walter and Heinz, Andreas and Rapp, Michael A.},
  title     = {Patterns of Alcohol Consumption Among Individuals With Alcohol Use Disorder During the COVID-19 Pandemic and Lockdowns in Germany},
  series = {JAMA Network Open},
  volume    = {5},
  journal   = {JAMA Network Open},
  edition   = {8},
  publisher = {JAMA Network / American Medical Association},
  address   = {Chicago, Illinois, USA},
  issn      = {2574-3805},
  doi       = {10.1001/jamanetworkopen.2022.24641},
  pages     = {1 -- 11},
  year      = {2022},
  abstract  = {Importance Alcohol consumption (AC) leads to death and disability worldwide. Ongoing discussions on potential negative effects of the COVID-19 pandemic on AC need to be informed by real-world evidence. Objective To examine whether lockdown measures are associated with AC and consumption-related temporal and psychological within-person mechanisms. Design, Setting, and Participants This quantitative, intensive, longitudinal cohort study recruited 1743 participants from 3 sites from February 20, 2020, to February 28, 2021. Data were provided before and within the second lockdown of the COVID-19 pandemic in Germany: before lockdown (October 2 to November 1, 2020); light lockdown (November 2 to December 15, 2020); and hard lockdown (December 16, 2020, to February 28, 2021). Main Outcomes and Measures Daily ratings of AC (main outcome) captured during 3 lockdown phases (main variable) and temporal (weekends and holidays) and psychological (social isolation and drinking intention) correlates. Results Of the 1743 screened participants, 189 (119 [63.0\%] male; median [IQR] age, 37 [27.5-52.0] years) with at least 2 alcohol use disorder (AUD) criteria according to the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) yet without the need for medically supervised alcohol withdrawal were included. These individuals provided 14 694 smartphone ratings from October 2020 through February 2021. Multilevel modeling revealed significantly higher AC (grams of alcohol per day) on weekend days vs weekdays (β = 11.39; 95\% CI, 10.00-12.77; P < .001). Alcohol consumption was above the overall average on Christmas (β = 26.82; 95\% CI, 21.87-31.77; P < .001) and New Year's Eve (β = 66.88; 95\% CI, 59.22-74.54; P < .001). During the hard lockdown, perceived social isolation was significantly higher (β = 0.12; 95\% CI, 0.06-0.15; P < .001), but AC was significantly lower (β = -5.45; 95\% CI, -8.00 to -2.90; P = .001). Independent of lockdown, intention to drink less alcohol was associated with lower AC (β = -11.10; 95\% CI, -13.63 to -8.58; P < .001). Notably, differences in AC between weekend and weekdays decreased both during the hard lockdown (β = -6.14; 95\% CI, -9.96 to -2.31; P = .002) and in participants with severe AUD (β = -6.26; 95\% CI, -10.18 to -2.34; P = .002). Conclusions and Relevance This 5-month cohort study found no immediate negative associations of lockdown measures with overall AC. Rather, weekend-weekday and holiday AC patterns exceeded lockdown effects. Differences in AC between weekend days and weekdays evinced that weekend drinking cycles decreased as a function of AUD severity and lockdown measures, indicating a potential mechanism of losing and regaining control. This finding suggests that temporal patterns and drinking intention constitute promising targets for prevention and intervention, even in high-risk individuals.},
  language  = {en}
}
@article{BrahmsHeinzelRappetal.2022,
  author    = {Brahms, Markus and Heinzel, Stephan and Rapp, Michael A. and M{\"u}ckstein, Marie and Hortob{\´a}gyi, Tibor and Stelzel, Christine and Granacher, Urs},
  title     = {The acute effects of mental fatigue on balance performance in healthy young and older adults - A systematic review and meta-analysis},
  series = {Acta Psychologica},
  volume    = {225},
  journal   = {Acta Psychologica},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-6297},
  doi       = {10.1016/j.actpsy.2022.103540},
  pages     = {1 -- 13},
  year      = {2022},
  abstract  = {Cognitive resources contribute to balance control. There is evidence that mental fatigue reduces cognitive resources and impairs balance performance, particularly in older adults and when balance tasks are complex, for example when trying to walk or stand while concurrently performing a secondary cognitive task. We conducted a systematic literature search in PubMed (MEDLINE), Web of Science and Google Scholar to identify eligible studies and performed a random effects meta-analysis to quantify the effects of experimentally induced mental fatigue on balance performance in healthy adults. Subgroup analyses were computed for age (healthy young vs. healthy older adults) and balance task complexity (balance tasks with high complexity vs. balance tasks with low complexity) to examine the moderating effects of these factors on fatigue-mediated balance performance. We identified 7 eligible studies with 9 study groups and 206 participants. Analysis revealed that performing a prolonged cognitive task had a small but significant effect (SMDwm = -0.38) on subsequent balance performance in healthy young and older adults. However, age- and task-related differences in balance responses to fatigue could not be confirmed statistically. Overall, aggregation of the available literature indicates that mental fatigue generally reduces balance in healthy adults. However, interactions between cognitive resource reduction, aging and balance task complexity remain elusive.},
  language  = {en}
}
@inproceedings{ClausenBruenkerStieglitz2023,
  author    = {Clausen, S{\"u}nje and Br{\"u}nker, Felix and Stieglitz, Stefan},
  title     = {Towards responsible augmentation},
  series = {ACIS 2023 proceedings},
  booktitle = {ACIS 2023 proceedings},
  publisher = {Australasian Association for Information Systems},
  address   = {Wellington},
  pages     = {9},
  year      = {2023},
  abstract  = {Artificial intelligence (AI)-based technologies can increasingly perform knowledge work tasks, such as medical diagnosis. Thereby, it is expected that humans will not be replaced by AI but work closely with AI-based technology ("augmentation"). Augmentation has ethical implications for humans (e.g., impact on autonomy, opportunities to flourish through work), thus, developers and managers of AI-based technology have a responsibility to anticipate and mitigate risks to human workers. However, doing so can be difficult as AI encompasses a wide range of technologies, some of which enable fundamentally new forms of interaction. In this research-in-progress paper, we propose the development of a taxonomy to categorize unique characteristics of AI-based technology that influence the interaction and have ethical implications for human workers. The completed taxonomy will support researchers in forming cumulative knowledge on the ethical implications of augmentation and assist practitioners in the ethical design and management of AI-based technology in knowledge work.},
  language  = {en}
}
@article{AgtheKayserSchwarzetal.2023,
  author    = {Agthe, Maria and Kayser, Daniela Niesta and Schwarz, Sascha and Maner, Jon K.},
  title     = {Antecedents of the red-romance effect},
  series = {PLOS ONE / Public Library of Science},
  volume    = {18},
  journal   = {PLOS ONE / Public Library of Science},
  number    = {4},
  publisher = {PLOS},
  address   = {San Fransisco},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0284035},
  pages     = {19},
  year      = {2023},
  abstract  = {The color red has been implicated in a variety of social processes, including those involving mating. While previous research suggests that women sometimes wear red strategically to increase their attractiveness, the replicability of this literature has been questioned. The current research is a reasonably powered conceptual replication designed to strengthen this literature by testing whether women are more inclined to display the color red 1) during fertile (as compared with less fertile) days of the menstrual cycle, and 2) when expecting to interact with an attractive man (as compared with a less attractive man and with a control condition). Analyses controlled for a number of theoretically relevant covariates (relationship status, age, the current weather). Only the latter hypothesis received mixed support (mainly among women on hormonal birth control), whereas results concerning the former hypothesis did not reach significance. Women (N = 281) displayed more red when expecting to interact with an attractive man; findings did not support the prediction that women would increase their display of red on fertile days of the cycle. Findings thus suggested only mixed replicability for the link between the color red and psychological processes involving romantic attraction. They also illustrate the importance of further investigating the boundary conditions of color effects on everyday social processes.},
  language  = {en}
}
@article{SchmickerFruehlingMenzeetal.2023,
  author    = {Schmicker, Marlen and Fr{\"u}hling, Insa and Menze, Inga and Glanz, Wenzel and M{\"u}ller, Patrick and Noesselt, Toemme and M{\"u}ller, Notger Germar},
  title     = {The potential role of gustatory function as an early diagnostic marker for the risk of alzheimer's disease in subjective cognitive decline},
  series = {Journal of Alzheimer's disease reports : JADR},
  volume    = {7},
  journal   = {Journal of Alzheimer's disease reports : JADR},
  number    = {1},
  publisher = {IOS Press},
  address   = {Clifton, VA},
  issn      = {2542-4823},
  doi       = {10.3233/ADR220092},
  pages     = {249 -- 262},
  year      = {2023},
  abstract  = {Background: Patients with subjective cognitive decline (SCD) report memory deterioration and are at an increased risk of converting to Alzheimer's disease (AD) although psychophysical testing does not reveal any cognitive deficit. Objective: Here, gustatory function is investigated as a potential predictor for an increased risk of progressive cognitive decline indicating higher AD risk in SCD. Methods: Measures of smell and taste perception as well as neuropsychological data were assessed in patients with subjective cognitive decline (SCD): Subgroups with an increased likelihood of the progression to preclinical AD (SCD+) and those with a lower likelihood (SCD-) were compared to healthy controls (HC), patients with mild cognitive impairment and AD patients. The Sniffin' Sticks test contained 12 items with different qualities and taste was measured with 32 taste stripes (sweet, salty, bitter, sour) of different concentration. Results: Only taste was able to distinguish between HC/SCD- and SCD+ patients. Conclusion: This study provides a first hint of taste as a more sensitive marker than smell for detecting preclinical AD in SCD. Longitudinal observation of cognition and pathology are necessary to further evaluate taste perception as a predictor of pathological objective decline in cognition.},
  language  = {en}
}
@article{XiongDelicZengetal.2022,
  author    = {Xiong, Yingquan and Delic, Denis and Zeng, Shufei and Chen, Xin and Chu, Chang and Hasan, Ahmed A. and Kr{\"a}mer, Bernhard K. and Klein, Thomas and Yin, Lianghong and Hocher, Berthold},
  title     = {Regulation of SARS CoV-2 host factors in the kidney and heart in rats with 5/6 nephrectomy-effects of salt, ARB, DPP4 inhibitor and SGLT2 blocker},
  series = {BMC nephrology},
  volume    = {23},
  journal   = {BMC nephrology},
  number    = {1},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {1471-2369},
  doi       = {10.1186/s12882-022-02747-1},
  pages     = {10},
  year      = {2022},
  abstract  = {Background Host factors such as angiotensin-converting enzyme 2 (ACE2) and the transmembrane protease, serine-subtype-2 (TMPRSS2) are important factors for SARS-CoV-2 infection. Clinical and pre-clinical studies demonstrated that RAAS-blocking agents can be safely used during a SARS-CoV-2 infection but it is unknown if DPP-4 inhibitors or SGLT2-blockers may promote COVID-19 by increasing the host viral entry enzymes ACE2 and TMPRSS2. Methods We investigated telmisartan, linagliptin and empagliflozin induced effects on renal and cardiac expression of ACE2, TMPRSS2 and key enzymes involved in RAAS (REN, AGTR2, AGT) under high-salt conditions in a non-diabetic experimental 5/6 nephrectomy (5/6 Nx) model. In the present study, the gene expression of Ace2, Tmprss2, Ren, Agtr2 and Agt was assessed with qRT-PCR and the protein expression of ACE2 and TMPRSS2 with immunohistochemistry in the following experimental groups: Sham + normal diet (ND) + placebo (PBO); 5/6Nx + ND + PBO; 5/6Nx + high salt-diet (HSD) + PBO; 5/6Nx + HSD + telmisartan; 5/6Nx + HSD + linagliptin; 5/6Nx + HSD + empagliflozin. Results In the kidney, the expression of Ace2 was not altered on mRNA level under disease and treatment conditions. The renal TMPRSS2 levels (mRNA and protein) were not affected, whereas the cardiac level was significantly increased in 5/6Nx rats. Intriguingly, the elevated TMPRSS2 protein expression in the heart was significantly normalized after treatment with telmisartan, linagliptin and empagliflozin. Conclusions Our study indicated that there is no upregulation regarding host factors potentially promoting SARS-CoV-2 virus entry into host cells when the SGLT2-blocker empagliflozin, telmisartan and the DPP4-inhibitor blocker linagliptin are used. The results obtained in a preclinical, experimental non-diabetic kidney failure model need confirmation in ongoing interventional clinical trials.},
  language  = {en}
}
@article{HeistermannFranckeScheiffeleetal.2023,
  author    = {Heistermann, Maik and Francke, Till and Scheiffele, Lena and Petrova, Katya Dimitrova and Budach, Christian and Schr{\"o}n, Martin and Trost, Benjamin and Rasche, Daniel and G{\"u}ntner, Andreas and Doepper, Veronika and F{\"o}rster, Michael and K{\"o}hli, Markus and Angermann, Lisa and Antonoglou, Nikolaos and Zude, Manuela and Oswald, Sascha},
  title     = {Three years of soil moisture observations by a dense cosmic-ray neutron sensing cluster at an agricultural research site in north-east Germany},
  series = {Earth system science data : ESSD},
  volume    = {15},
  journal   = {Earth system science data : ESSD},
  number    = {7},
  publisher = {Copernics Publications},
  address   = {Katlenburg-Lindau},
  issn      = {1866-3508},
  doi       = {10.5194/essd-15-3243-2023},
  pages     = {3243 -- 3262},
  year      = {2023},
  abstract  = {Cosmic-ray neutron sensing (CRNS) allows for the estimation of root-zone soil water content (SWC) at the scale of several hectares. In this paper, we present the data recorded by a dense CRNS network operated from 2019 to 2022 at an agricultural research site in Marquardt, Germany - the first multi-year CRNS cluster. Consisting, at its core, of eight permanently installed CRNS sensors, the cluster was supplemented by a wealth of complementary measurements: data from seven additional temporary CRNS sensors, partly co-located with the permanent ones; 27 SWC profiles (mostly permanent); two groundwater observation wells; meteorological records; and Global Navigation Satellite System reflectometry (GNSS-R). Complementary to these continuous measurements, numerous campaign-based activities provided data by mobile CRNS roving, hyperspectral im-agery via UASs, intensive manual sampling of soil properties (SWC, bulk density, organic matter, texture, soil hydraulic properties), and observations of biomass and snow (cover, depth, and density). The unique temporal coverage of 3 years entails a broad spectrum of hydro-meteorological conditions, including exceptional drought periods and extreme rainfall but also episodes of snow coverage, as well as a dedicated irrigation experiment. Apart from serving to advance CRNS-related retrieval methods, this data set is expected to be useful for vari-ous disciplines, for example, soil and groundwater hydrology, agriculture, or remote sensing. Hence, we show exemplary features of the data set in order to highlight the potential for such subsequent studies. The data are available at doi.org/10.23728/b2share.551095325d74431881185fba1eb09c95 (Heistermann et al., 2022b).},
  language  = {en}
}
@article{ShamsWangRoineetal.2022,
  author    = {Shams, Boshra and Wang, Ziqian and Roine, Timo and Aydogan, Dogu Baran and Vajkoczy, Peter and Lippert, Christoph and Picht, Thomas and Fekonja, Lucius Samo},
  title     = {Machine learning-based prediction of motor status in glioma patients using diffusion MRI metrics along the corticospinal tract},
  series = {Brain communications},
  volume    = {4},
  journal   = {Brain communications},
  number    = {3},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {2632-1297},
  doi       = {10.1093/braincomms/fcac141},
  pages     = {17},
  year      = {2022},
  abstract  = {Shams et al. report that glioma patients' motor status is predicted accurately by diffusion MRI metrics along the corticospinal tract based on support vector machine method, reaching an overall accuracy of 77\%. They show that these metrics are more effective than demographic and clinical variables. Along tract statistics enables white matter characterization using various diffusion MRI metrics. These diffusion models reveal detailed insights into white matter microstructural changes with development, pathology and function. Here, we aim at assessing the clinical utility of diffusion MRI metrics along the corticospinal tract, investigating whether motor glioma patients can be classified with respect to their motor status. We retrospectively included 116 brain tumour patients suffering from either left or right supratentorial, unilateral World Health Organization Grades II, III and IV gliomas with a mean age of 53.51 +/- 16.32 years. Around 37\% of patients presented with preoperative motor function deficits according to the Medical Research Council scale. At group level comparison, the highest non-overlapping diffusion MRI differences were detected in the superior portion of the tracts' profiles. Fractional anisotropy and fibre density decrease, apparent diffusion coefficient axial diffusivity and radial diffusivity increase. To predict motor deficits, we developed a method based on a support vector machine using histogram-based features of diffusion MRI tract profiles (e.g. mean, standard deviation, kurtosis and skewness), following a recursive feature elimination method. Our model achieved high performance (74\% sensitivity, 75\% specificity, 74\% overall accuracy and 77\% area under the curve). We found that apparent diffusion coefficient, fractional anisotropy and radial diffusivity contributed more than other features to the model. Incorporating the patient demographics and clinical features such as age, tumour World Health Organization grade, tumour location, gender and resting motor threshold did not affect the model's performance, revealing that these features were not as effective as microstructural measures. These results shed light on the potential patterns of tumour-related microstructural white matter changes in the prediction of functional deficits.},
  language  = {en}
}
@article{deCarvalhoSouzaBarrocasFischeretal.2023,
  author    = {de Carvalho Souza, Alyson Matheus and Barrocas, Roberta and Fischer, Martin H. and Arnaud, Emanuel and Moeller, Korbinian and Renn{\´o}-Costa, C{\´e}sar},
  title     = {Combining virtual reality and tactile stimulation to investigate embodied finger-based numerical representations},
  series = {Frontiers in psychology / Frontiers Research Foundation},
  volume    = {14},
  journal   = {Frontiers in psychology / Frontiers Research Foundation},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2023.1119561},
  pages     = {13},
  year      = {2023},
  abstract  = {Finger-based representation of numbers is a high-level cognitive strategy to assist numerical and arithmetic processing in children and adults. It is unclear whether this paradigm builds on simple perceptual features or comprises several attributes through embodiment. Here we describe the development and initial testing of an experimental setup to study embodiment during a finger-based numerical task using Virtual Reality (VR) and a low-cost tactile stimulator that is easy to build. Using VR allows us to create new ways to study finger-based numerical representation using a virtual hand that can be manipulated in ways our hand cannot, such as decoupling tactile and visual stimuli. The goal is to present a new methodology that can allow researchers to study embodiment through this new approach, maybe shedding new light on the cognitive strategy behind the finger-based representation of numbers. In this case, a critical methodological requirement is delivering precisely targeted sensory stimuli to specific effectors while simultaneously recording their behavior and engaging the participant in a simulated experience. We tested the device's capability by stimulating users in different experimental configurations. Results indicate that our device delivers reliable tactile stimulation to all fingers of a participant's hand without losing motion tracking quality during an ongoing task. This is reflected by an accuracy of over 95\% in participants detecting stimulation of a single finger or multiple fingers in sequential stimulation as indicated by experiments with sixteen participants. We discuss possible application scenarios, explain how to apply our methodology to study the embodiment of finger-based numerical representations and other high-level cognitive functions, and discuss potential further developments of the device based on the data obtained in our testing.},
  language  = {en}
}
@article{StueblerKloftHuisinga2023,
  author    = {St{\"u}bler, Sabine and Kloft, Charlotte and Huisinga, Wilhelm},
  title     = {Cell-level systems biology model to study inflammatory bowel diseases and their treatment options},
  series = {CPT: pharmacometrics \& systems pharmacology},
  volume    = {12},
  journal   = {CPT: pharmacometrics \& systems pharmacology},
  number    = {5},
  publisher = {Nature Publ. Group},
  address   = {London},
  issn      = {2163-8306},
  doi       = {10.1002/psp4.12932},
  pages     = {690 -- 705},
  year      = {2023},
  abstract  = {To help understand the complex and therapeutically challenging inflammatory bowel diseases (IBDs), we developed a systems biology model of the intestinal immune system that is able to describe main aspects of IBD and different treatment modalities thereof. The model, including key cell types and processes of the mucosal immune response, compiles a large amount of isolated experimental findings from literature into a larger context and allows for simulations of different inflammation scenarios based on the underlying data and assumptions. In the context of a large and diverse virtual IBD population, we characterized the patients based on their phenotype (in contrast to healthy individuals, they developed persistent inflammation after a trigger event) rather than on a priori assumptions on parameter differences to a healthy individual. This allowed to reproduce the enormous diversity of predispositions known to lead to IBD. Analyzing different treatment effects, the model provides insight into characteristics of individual drug therapy. We illustrate for anti-TNF-alpha therapy, how the model can be used (i) to decide for alternative treatments with best prospects in the case of nonresponse, and (ii) to identify promising combination therapies with other available treatment options.},
  language  = {en}
}
@article{KayaDupontNivetFrielingetal.2022,
  author    = {Kaya, Mustafa Y{\"u}cel and Dupont-Nivet, Guillaume and Frieling, Joost and Fioroni, Chiara and Rohrmann, Alexander and Alt{\i}ner, Sevin{\c{c}} {\"O}zkan and Vardar, Ezgi and Tanyas, Hakan and Mamtimin, Mehmut and Zhaojie, Guo},
  title     = {The Eurasian epicontinental sea was an important carbon sink during the Palaeocene-Eocene thermal maximum},
  series = {Communications earth and environment},
  volume    = {3},
  journal   = {Communications earth and environment},
  number    = {1},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2662-4435},
  doi       = {10.1038/s43247-022-00451-4},
  pages     = {10},
  year      = {2022},
  abstract  = {The Palaeocene-Eocene Thermal Maximum (ca. 56 million years ago) offers a primary analogue for future global warming and carbon cycle recovery. Yet, where and how massive carbon emissions were mitigated during this climate warming event remains largely unknown. Here we show that organic carbon burial in the vast epicontinental seaways that extended over Eurasia provided a major carbon sink during the Palaeocene-Eocene Thermal Maximum. We coupled new and existing stratigraphic analyses to a detailed paleogeographic framework and using spatiotemporal interpolation calculated ca. 720-1300 Gt organic carbon excess burial, focused in the eastern parts of the Eurasian epicontinental seaways. A much larger amount (2160-3900 Gt C, and when accounting for the increase in inundated shelf area 7400-10300 Gt C) could have been sequestered in similar environments globally. With the disappearance of most epicontinental seas since the Oligocene-Miocene, an effective negative carbon cycle feedback also disappeared making the modern carbon cycle critically dependent on the slower silicate weathering feedback.},
  language  = {en}
}
@article{vanSoestAleluiaReisBaptistaetal.2021,
  author    = {van Soest, Heleen L. and Aleluia Reis, Lara and Baptista, Luiz Bernardo and Bertram, Christoph and Despr{\´e}s, Jacques and Drouet, Laurent and den Elzen, Michel and Fragkos, Panagiotis and Fricko, Oliver and Fujimori, Shinichiro and Grant, Neil and Harmsen, Mathijs and Iyer, Gokul and Keramidas, Kimon and K{\"o}berle, Alexandre C. and Kriegler, Elmar and Malik, Aman and Mittal, Shivika and Oshiro, Ken and Riahi, Keywan and Roelfsema, Mark and van Ruijven, Bas and Schaeffer, Roberto and Silva Herran, Diego and Tavoni, Massimo and {\"U}nl{\"u}, Gamze and Vandyck, Toon and van Vuuren, Detlef P.},
  title     = {Global roll-out of comprehensive policy measures may aid in bridging emissions gap},
  series = {Nature communications},
  volume    = {12},
  journal   = {Nature communications},
  number    = {1},
  publisher = {Nature Publishing Group UK},
  address   = {London},
  doi       = {10.1038/s41467-021-26595-z},
  pages     = {10},
  year      = {2021},
  abstract  = {Closing the emissions gap between Nationally Determined Contributions (NDCs) and the global emissions levels needed to achieve the Paris Agreement's climate goals will require a comprehensive package of policy measures. National and sectoral policies can help fill the gap, but success stories in one country cannot be automatically replicated in other countries. They need to be adapted to the local context. Here, we develop a new Bridge scenario based on nationally relevant, short-term measures informed by interactions with country experts. These good practice policies are rolled out globally between now and 2030 and combined with carbon pricing thereafter. We implement this scenario with an ensemble of global integrated assessment models. We show that the Bridge scenario closes two-thirds of the emissions gap between NDC and 2 °C scenarios by 2030 and enables a pathway in line with the 2 °C goal when combined with the necessary long-term changes, i.e. more comprehensive pricing measures after 2030. The Bridge scenario leads to a scale-up of renewable energy (reaching 52\%-88\% of global electricity supply by 2050), electrification of end-uses, efficiency improvements in energy demand sectors, and enhanced afforestation and reforestation. Our analysis suggests that early action via good-practice policies is less costly than a delay in global climate cooperation.},
  language  = {en}
}
@article{YeZhangWarbyetal.2022,
  author    = {Ye, Fangyuan and Zhang, Shuo and Warby, Jonathan and Wu, Jiawei and Gutierrez-Partida, Emilio and Lang, Felix and Shah, Sahil and Saglamkaya, Elifnaz and Sun, Bowen and Zu, Fengshuo and Shoai, Safa and Wang, Haifeng and Stiller, Burkhard and Neher, Dieter and Zhu, Wei-Hong and Stolterfoht, Martin and Wu, Yongzhen},
  title     = {Overcoming C₆₀-induced interfacial recombination in inverted perovskite solar cells by electron-transporting carborane},
  series = {Nature Communications},
  volume    = {13},
  journal   = {Nature Communications},
  number    = {1},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2041-1723},
  doi       = {10.1038/s41467-022-34203-x},
  pages     = {12},
  year      = {2022},
  abstract  = {Inverted perovskite solar cells still suffer from significant non-radiative recombination losses at the perovskite surface and across the perovskite/C₆₀ interface, limiting the future development of perovskite-based single- and multi-junction photovoltaics. Therefore, more effective inter- or transport layers are urgently required. To tackle these recombination losses, we introduce ortho-carborane as an interlayer material that has a spherical molecular structure and a three-dimensional aromaticity. Based on a variety of experimental techniques, we show that ortho-carborane decorated with phenylamino groups effectively passivates the perovskite surface and essentially eliminates the non-radiative recombination loss across the perovskite/C₆₀ interface with high thermal stability. We further demonstrate the potential of carborane as an electron transport material, facilitating electron extraction while blocking holes from the interface. The resulting inverted perovskite solar cells deliver a power conversion efficiency of over 23\% with a low non-radiative voltage loss of 110 mV, and retain >97\% of the initial efficiency after 400 h of maximum power point tracking. Overall, the designed carborane based interlayer simultaneously enables passivation, electron-transport and hole-blocking and paves the way toward more efficient and stable perovskite solar cells.},
  language  = {en}
}
@article{EhrigWagnerWolteretal.2023,
  author    = {Ehrig, Lukas and Wagner, Ann-Christin and Wolter, Heike and Correll, Christoph U. and Geisel, Olga and Konigorski, Stefan},
  title     = {FASDetect as a machine learning-based screening app for FASD in youth with ADHD},
  series = {npj Digital Medicine},
  volume    = {6},
  journal   = {npj Digital Medicine},
  number    = {1},
  publisher = {Macmillan Publishers Limited},
  address   = {Basingstoke},
  issn      = {2398-6352},
  doi       = {10.1038/s41746-023-00864-1},
  pages     = {9},
  year      = {2023},
  abstract  = {Fetal alcohol-spectrum disorder (FASD) is underdiagnosed and often misdiagnosed as attention-deficit/hyperactivity disorder (ADHD). Here, we develop a screening tool for FASD in youth with ADHD symptoms. To develop the prediction model, medical record data from a German University outpatient unit are assessed including 275 patients aged 0-19 years old with FASD with or without ADHD and 170 patients with ADHD without FASD aged 0-19 years old. We train 6 machine learning models based on 13 selected variables and evaluate their performance. Random forest models yield the best prediction models with a cross-validated AUC of 0.92 (95\% confidence interval [0.84, 0.99]). Follow-up analyses indicate that a random forest model with 6 variables - body length and head circumference at birth, IQ, socially intrusive behaviour, poor memory and sleep disturbance - yields equivalent predictive accuracy. We implement the prediction model in a web-based app called FASDetect - a user-friendly, clinically scalable FASD risk calculator that is freely available at https://fasdetect.dhc-lab.hpi.de.},
  language  = {en}
}
@article{SlosarekIbingSchormairetal.2023,
  author    = {Slosarek, Tamara and Ibing, Susanne and Schormair, Barbara and Heyne, Henrike and B{\"o}ttinger, Erwin and Andlauer, Till and Schurmann, Claudia},
  title     = {Implementation and evaluation of personal genetic testing as part of genomics analysis courses in German universities},
  series = {BMC Medical Genomics},
  volume    = {16},
  journal   = {BMC Medical Genomics},
  number    = {1},
  publisher = {BMC},
  address   = {London},
  issn      = {1755-8794},
  doi       = {10.1186/s12920-023-01503-0},
  pages     = {13},
  year      = {2023},
  abstract  = {Purpose Due to the increasing application of genome analysis and interpretation in medical disciplines, professionals require adequate education. Here, we present the implementation of personal genotyping as an educational tool in two genomics courses targeting Digital Health students at the Hasso Plattner Institute (HPI) and medical students at the Technical University of Munich (TUM). Methods We compared and evaluated the courses and the students ' perceptions on the course setup using questionnaires. Results During the course, students changed their attitudes towards genotyping (HPI: 79\% [15 of 19], TUM: 47\% [25 of 53]). Predominantly, students became more critical of personal genotyping (HPI: 73\% [11 of 15], TUM: 72\% [18 of 25]) and most students stated that genetic analyses should not be allowed without genetic counseling (HPI: 79\% [15 of 19], TUM: 70\% [37 of 53]). Students found the personal genotyping component useful (HPI: 89\% [17 of 19], TUM: 92\% [49 of 53]) and recommended its inclusion in future courses (HPI: 95\% [18 of 19], TUM: 98\% [52 of 53]). Conclusion Students perceived the personal genotyping component as valuable in the described genomics courses. The implementation described here can serve as an example for future courses in Europe.},
  language  = {en}
}
@inproceedings{RieskampMirbabaieHofeditzetal.2023,
  author    = {Rieskamp, Jonas and Mirbabaie, Milad and Hofeditz, Lennart and Vischedyk, Justin},
  title     = {Conversational agents and their influence on the well-being of cliniciansclinicians},
  series = {ACIS 2023 proceedings},
  booktitle = {ACIS 2023 proceedings},
  publisher = {Australasian Association for Information Systems},
  address   = {Wellington},
  pages     = {16},
  year      = {2023},
  abstract  = {An increasing number of clinicians (i.e., nurses and physicians) suffer from mental health-related issues like depression and burnout. These, in turn, stress communication, collaboration, and decision- making—areas in which Conversational Agents (CAs) have shown to be useful. Thus, in this work, we followed a mixed-method approach and systematically analysed the literature on factors affecting the well-being of clinicians and CAs' potential to improve said well-being by relieving support in communication, collaboration, and decision-making in hospitals. In this respect, we are guided by Brigham et al. (2018)'s model of factors influencing well-being. Based on an initial number of 840 articles, we further analysed 52 papers in more detail and identified the influences of CAs' fields of application on external and individual factors affecting clinicians' well-being. As our second method, we will conduct interviews with clinicians and experts on CAs to verify and extend these influencing factors.},
  language  = {en}
}
@article{GischRobertBerlinetal.2022,
  author    = {Gisch, Ulrike Alexandra and Robert, Margaux and Berlin, Noemi and Nebout, Antoine and Etile, Fabrice and Teyssier, Sabrina and Andreeva, Valentina A. and Hercberg, Serge and Touvier, Mathilde and Peneau, Sandrine},
  title     = {Mastery is associated with weight status, food intake, snacking, and eating disorder symptoms in the NutriNet-Sante cohort study},
  series = {Frontiers in Nutrition},
  volume    = {9},
  journal   = {Frontiers in Nutrition},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-861X},
  doi       = {10.3389/fnut.2022.871669},
  pages     = {13},
  year      = {2022},
  abstract  = {Mastery is a psychological resource that is defined as the extent to which individuals perceive having control over important circumstances of their lives. Although mastery has been associated with various physical and psychological health outcomes, studies assessing its relationship with weight status and dietary behavior are lacking. The aim of this cross-sectional study was to assess the relationship between mastery and weight status, food intake, snacking, and eating disorder (ED) symptoms in the NutriNet-Sante cohort study. Mastery was measured with the Pearlin Mastery Scale (PMS) in 32,588 adults (77.45\% female), the mean age was 50.04 (14.53) years. Height and weight were self-reported. Overall diet quality and food group consumption were evaluated with >= 3 self-reported 24-h dietary records (range: 3-27). Snacking was assessed with an ad-hoc question. ED symptoms were assessed with the Sick-Control-One-Fat-Food Questionnaire (SCOFF). Linear and logistic regression analyses were conducted to assess the relationship between mastery and weight status, food intake, snacking, and ED symptoms, controlling for sociodemographic and lifestyle characteristics. Females with a higher level of mastery were less likely to be underweight (OR: 0.88; 95\%CI: 0.84, 0.93), overweight [OR: 0.94 (0.91, 0.97)], or obese [class I: OR: 0.86 (0.82, 0.90); class II: OR: 0.76 (0.71, 0.82); class III: OR: 0.77 (0.69, 0.86)]. Males with a higher level of mastery were less likely to be obese [class III: OR: 0.75 (0.57, 0.99)]. Mastery was associated with better diet quality overall, a higher consumption of fruit and vegetables, seafood, wholegrain foods, legumes, non-salted oleaginous fruits, and alcoholic beverages and with a lower consumption of meat and poultry, dairy products, sugary and fatty products, milk-based desserts, and sweetened beverages. Mastery was also associated with lower snacking frequency [OR: 0.89 (0.86, 0.91)] and less ED symptoms [OR: 0.73 (0.71, 0.75)]. As mastery was associated with favorable dietary behavior and weight status, targeting mastery might be a promising approach in promoting healthy behaviors.},
  language  = {en}
}
@inproceedings{MarxBruenkerMirbabaieetal.2024,
  author    = {Marx, Julian and Br{\"u}nker, Felix and Mirbabaie, Milad and Stieglitz, Stefan},
  title     = {Digital activism on social media},
  series = {Proceedings of the 57th Annual Hawaii International Conference on System Sciences},
  booktitle = {Proceedings of the 57th Annual Hawaii International Conference on System Sciences},
  editor    = {Bui, Tung X.},
  publisher = {Department of IT Management Shidler College of Business University of Hawaii},
  address   = {Honolulu, HI},
  isbn      = {978-0-99813-317-1},
  pages     = {7205 -- 7214},
  year      = {2024},
  abstract  = {Social media constitute an important arena for public debates and steady interchange of issues relevant to society. To boost their reputation, commercial organizations also engage in political, social, or environmental debates on social media. To engage in this type of digital activism, organizations increasingly utilize the social media profiles of executive employees and other brand ambassadors. However, the relationship between brand ambassadors' digital activism and corporate reputation is only vaguely understood. The results of a qualitative inquiry suggest that digital activism via brand ambassadors can be risky (e.g., creating additional surface for firestorms, financial loss) and rewarding (e.g., emitting authenticity, employing 'megaphones' for industry change) at the same time. The paper informs both scholarship and practitioners about strategic trade-offs that need to be considered when employing brand ambassadors for digital activism.},
  language  = {en}
}
@inproceedings{MirbabaieRieskampHofeditzetal.2024,
  author    = {Mirbabaie, Milad and Rieskamp, Jonas and Hofeditz, Lennart and Stieglitz, Stefan},
  title     = {Breaking down barriers},
  series = {Proceedings of the 57th Annual Hawaii International Conference on System Sciences},
  booktitle = {Proceedings of the 57th Annual Hawaii International Conference on System Sciences},
  editor    = {Bui, Tung X.},
  publisher = {Department of IT Management Shidler College of Business University of Hawaii},
  address   = {Honolulu, HI},
  isbn      = {978-0-99813-317-1},
  pages     = {672 -- 681},
  year      = {2024},
  abstract  = {Many researchers hesitate to provide full access to their datasets due to a lack of knowledge about research data management (RDM) tools and perceived fears, such as losing the value of one's own data. Existing tools and approaches often do not take into account these fears and missing knowledge. In this study, we examined how conversational agents (CAs) can provide a natural way of guidance through RDM processes and nudge researchers towards more data sharing. This work offers an online experiment in which researchers interacted with a CA on a self-developed RDM platform and a survey on participants' data sharing behavior. Our findings indicate that the presence of a guiding and enlightening CA on an RDM platform has a constructive influence on both the intention to share data and the actual behavior of data sharing. Notably, individual factors do not appear to impede or hinder this effect.},
  language  = {en}
}
@article{ReilRosenfeldImholtetal.2017,
  author    = {Reil, Daniela and Rosenfeld, Ulrike and Imholt, Christian and Schmidt, Sabrina and Ulrich, Rainer G. and Eccard, Jana and Jacob, Jens},
  title     = {Puumala hantavirus infections in bank vole populations},
  series = {BMC ecology},
  volume    = {17},
  journal   = {BMC ecology},
  publisher = {BioMed Central},
  address   = {London},
  issn      = {1472-6785},
  doi       = {10.1186/s12898-017-0118-z},
  pages     = {13},
  year      = {2017},
  abstract  = {Background In Europe, bank voles (Myodes glareolus) are widely distributed and can transmit Puumala virus (PUUV) to humans, which causes a mild to moderate form of haemorrhagic fever with renal syndrome, called nephropathia epidemica. Uncovering the link between host and virus dynamics can help to prevent human PUUV infections in the future. Bank voles were live trapped three times a year in 2010-2013 in three woodland plots in each of four regions in Germany. Bank vole population density was estimated and blood samples collected to detect PUUV specific antibodies. Results We demonstrated that fluctuation of PUUV seroprevalence is dependent not only on multi-annual but also on seasonal dynamics of rodent host abundance. Moreover, PUUV infection might affect host fitness, because seropositive individuals survived better from spring to summer than uninfected bank voles. Individual space use was independent of PUUV infections. Conclusions Our study provides robust estimations of relevant patterns and processes of the dynamics of PUUV and its rodent host in Central Europe, which are highly important for the future development of predictive models for human hantavirus infection risk},
  language  = {en}
}
@misc{MorenoRomeroProbstTrindadeetal.2020,
  author    = {Moreno-Romero, Jordi and Probst, Aline V. and Trindade, In{\^e}s and Kalyanikrishna, and Engelhorn, Julia and Farrona, Sara},
  title     = {Looking At the Past and Heading to the Future},
  series = {Frontiers in Plant Science},
  volume    = {10},
  journal   = {Frontiers in Plant Science},
  number    = {1795},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {1664-462X},
  doi       = {10.3389/fpls.2019.01795},
  pages     = {1 -- 12},
  year      = {2020},
  abstract  = {In June 2019, more than a hundred plant researchers met in Cologne, Germany, for the 6th European Workshop on Plant Chromatin (EWPC). This conference brought together a highly dynamic community of researchers with the common aim to understand how chromatin organization controls gene expression, development, and plant responses to the environment. New evidence showing how epigenetic states are set, perpetuated, and inherited were presented, and novel data related to the three-dimensional organization of chromatin within the nucleus were discussed. At the level of the nucleosome, its composition by different histone variants and their specialized histone deposition complexes were addressed as well as the mechanisms involved in histone post-translational modifications and their role in gene expression. The keynote lecture on plant DNA methylation by Julie Law (SALK Institute) and the tribute session to Lars Hennig, honoring the memory of one of the founders of the EWPC who contributed to promote the plant chromatin and epigenetic field in Europe, added a very special note to this gathering. In this perspective article we summarize some of the most outstanding data and advances on plant chromatin research presented at this workshop.},
  language  = {en}
}
@misc{Grohmann2022,
  author    = {Grohmann, Nils-Hendrik},
  title     = {How to avoid politicised monitoring?},
  series = {V{\"o}lkerrechtsblog : Der Blog des Arbeitskreis junger V{\"o}lkerrechtswissenschaftler*innen},
  journal   = {V{\"o}lkerrechtsblog : Der Blog des Arbeitskreis junger V{\"o}lkerrechtswissenschaftler*innen},
  publisher = {M. Riegner c/o Humboldt-Univ},
  address   = {Berlin},
  issn      = {2510-2567},
  doi       = {10.17176/20220623-153108-0},
  pages     = {4},
  year      = {2022},
  language  = {en}
}
@article{PangDietrichTewsetal.2020,
  author    = {Pang, Peter Tsun Ho and Dietrich, Tim and Tews, Ingo and Van Den Broeck, Chris},
  title     = {Parameter estimation for strong phase transitions in supranuclear matter using gravitational-wave astronomy},
  series = {Physical review research},
  volume    = {2},
  journal   = {Physical review research},
  number    = {3},
  publisher = {American Physical Society},
  address   = {College Park},
  issn      = {2643-1564},
  doi       = {10.1103/PhysRevResearch.2.033514},
  pages     = {17},
  year      = {2020},
  abstract  = {At supranuclear densities, explored in the core of neutron stars, a strong phase transition from hadronic matter to more exotic forms of matter might be present. To test this hypothesis, binary neutron-star mergers offer a unique possibility to probe matter at densities that we cannot create in any existing terrestrial experiment. In this work, we show that, if present, strong phase transitions can have a measurable imprint on the binary neutron-star coalescence and the emitted gravitational-wave signal. We construct a new parametrization of the supranuclear equation of state that allows us to test for the existence of a strong phase transition and extract its characteristic properties purely from the gravitational-wave signal of the inspiraling neutron stars. We test our approach using a Bayesian inference study simulating 600 signals with three different equations of state and find that for current gravitational-wave detector networks already 12 events might be sufficient to verify the presence of a strong phase transition. Finally, we use our methodology to analyze GW170817 and GW190425 but do not find any indication that a strong phase transition is present at densities probed during the inspiral.},
  language  = {en}
}
@article{BoschDeCesareDemskeetal.2023,
  author    = {Bosch, Sina and De Cesare, Ilaria and Demske, Ulrike and Felser, Claudia},
  title     = {Word-order variation and coherence in German infinitival complementation},
  series = {The journal of comparative Germanic linguistics},
  volume    = {26},
  journal   = {The journal of comparative Germanic linguistics},
  number    = {1},
  publisher = {Springer},
  address   = {New York},
  issn      = {1572-8552},
  doi       = {10.1007/s10828-023-09140-8},
  pages     = {43},
  year      = {2023},
  abstract  = {This study provides a synthesis of corpus-based and experimental investigations of word-order preferences in German infinitival complementation. We carried out a systematic analysis of present-day German corpora to establish frequency distributions of different word-order options: extraposition, intraposition, and 'third construction'. We then examined, firstly, whether and to what extent corpus frequencies and processing economy constraints can predict the acceptability of these three word-order variants, and whether subject raising and subject control verbs form clearly distinguishable subclasses of infinitive-embedding verbs in terms of their word-order behaviour. Secondly, our study looks into the issue of coherence by comparing acceptability ratings for monoclausal coherent and biclausal incoherent construals of intraposed infinitives, and by examining whether a biclausal incoherent analysis gives rise to local and/or global processing difficulty. Taken together, our results revealed that (i) whilst the extraposition pattern consistently wins out over all other word-order variants for control verbs, neither frequency nor processing-based approaches to word-order variation can account for the acceptability of low-frequency variants, (ii) there is considerable verb-specific variation regarding word-order preferences both between and within the two sets of raising and control verbs under investigation, and (iii) although monoclausal coherent intraposition is rated above biclausal incoherent intraposition, the latter is not any more difficult to process than the former. Our findings indicate that frequency of occurrence and processing-related constraints interact with idiosyncratic lexical properties of individual verbs in determining German speakers' structural preferences.},
  language  = {en}
}
@misc{BullaCoughlinDhawanetal.2022,
  author    = {Bulla, Mattia and Coughlin, Michael W. and Dhawan, Suhail and Dietrich, Tim},
  title     = {Multi-messenger constraints on the Hubble constant through combination of gravitational waves, gamma-ray bursts and kilonovae from neutron star mergers},
  series = {Universe : open access journal},
  volume    = {8},
  journal   = {Universe : open access journal},
  number    = {5},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2218-1997},
  doi       = {10.3390/universe8050289},
  pages     = {21},
  year      = {2022},
  abstract  = {The simultaneous detection of gravitational waves and light from the binary neutron star merger GW170817 led to independent measurements of distance and redshift, providing a direct estimate of the Hubble constant H-0 that does not rely on a cosmic distance ladder, nor assumes a specific cosmological model. By using gravitational waves as "standard sirens", this approach holds promise to arbitrate the existing tension between the H-0 value inferred from the cosmic microwave background and those obtained from local measurements. However, the known degeneracy in the gravitational-wave analysis between distance and inclination of the source led to a H-0 value from GW170817 that was not precise enough to resolve the existing tension. In this review, we summarize recent works exploiting the viewing-angle dependence of the electromagnetic signal, namely the associated short gamma-ray burst and kilonova, to constrain the system inclination and improve on H-0. We outline the key ingredients of the different methods, summarize the results obtained in the aftermath of GW170817 and discuss the possible systematics introduced by each of these methods.},
  language  = {en}
}
@article{WachsWrightSittichaietal.2019,
  author    = {Wachs, Sebastian and Wright, Michelle F. and Sittichai, Ruthaychonnee and Singh, Ritu and Biswal, Ramakrishna and Kim, Eun-mee and Yang, Soeun and G{\´a}mez-Guadix, Manuel and Almendros, Carmen and Flora, Katerina and Daskalou, Vassiliki and Maziridou, Evdoxia},
  title     = {Associations between witnessing and perpetrating online hate in eight countries},
  series = {International Journal of Environmental Research and Public Health},
  volume    = {16},
  journal   = {International Journal of Environmental Research and Public Health},
  number    = {20},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1660-4601},
  doi       = {10.3390/ijerph16203992},
  pages     = {13},
  year      = {2019},
  abstract  = {Online hate is a topic that has received considerable interest lately, as online hate represents a risk to self-determination and peaceful coexistence in societies around the globe. However, not much is known about the explanations for adolescents posting or forwarding hateful online material or how adolescents cope with this newly emerging online risk. Thus, we sought to better understand the relationship between a bystander to and perpetrator of online hate, and the moderating effects of problem-focused coping strategies (e.g., assertive, technical coping) within this relationship. Self-report questionnaires on witnessing and committing online hate and assertive and technical coping were completed by 6829 adolescents between 12 and 18 years of age from eight countries. The results showed that increases in witnessing online hate were positively related to being a perpetrator of online hate. Assertive and technical coping strategies were negatively related with perpetrating online hate. Bystanders of online hate reported fewer instances of perpetrating online hate when they reported higher levels of assertive and technical coping strategies, and more frequent instances of perpetrating online hate when they reported lower levels of assertive and technical coping strategies. In conclusion, our findings suggest that, if effective, prevention and intervention programs that target online hate should consider educating young people about problem-focused coping strategies, self-assertiveness, and media skills. Implications for future research are discussed.},
  language  = {en}
}
@misc{WachsWrightSittichai2021,
  author    = {Wachs, Sebastian and Wright, Michelle F. and Sittichai, Ruthaychonnee},
  title     = {Correction: Associations between witnessing and perpetrating online hate in eight countries: The Buffering Effects of Problem-Focused Coping.},
  series = {International Journal Environmental Research and Public Health},
  volume    = {18},
  journal   = {International Journal Environmental Research and Public Health},
  number    = {3992},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1660-4601},
  doi       = {10.3390/ijerph18052609},
  pages     = {1 -- 2},
  year      = {2021},
  abstract  = {Kein Abstract vorhanden},
  language  = {en}
}
@article{DellepianeVaidJaladankietal.2021,
  author    = {Dellepiane, Sergio and Vaid, Akhil and Jaladanki, Suraj K. and Coca, Steven and Fayad, Zahi A. and Charney, Alexander W. and B{\"o}ttinger, Erwin and He, John Cijiang and Glicksberg, Benjamin S. and Chan, Lili and Nadkarni, Girish},
  title     = {Acute kidney injury in patients hospitalized with COVID-19 in New York City},
  series = {Kidney medicine},
  volume    = {3},
  journal   = {Kidney medicine},
  number    = {5},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2590-0595},
  doi       = {10.1016/j.xkme.2021.06.008},
  pages     = {877 -- 879},
  year      = {2021},
  language  = {en}
}
@article{KowalczykAmannStrefleretal.2024,
  author    = {Kowalczyk, Katarzyna A. and Amann, Thorben and Strefler, Jessica and Vorrath, Maria-Elena and Hartmann, Jens and de Marco, Serena and Renforth, Phil and Foteinis, Spyros and Kriegler, Elmar},
  title     = {Marine carbon dioxide removal by alkalinization should no longer be overlooked},
  series = {Environmental research letters},
  volume    = {19},
  journal   = {Environmental research letters},
  number    = {7},
  publisher = {IOP Publishing},
  address   = {Bristol},
  issn      = {1748-9326},
  doi       = {10.1088/1748-9326/ad5192},
  pages     = {12},
  year      = {2024},
  abstract  = {To achieve the Paris climate target, deep emissions reductions have to be complemented with carbon dioxide removal (CDR). However, a portfolio of CDR options is necessary to reduce risks and potential negative side effects. Despite a large theoretical potential, ocean-based CDR such as ocean alkalinity enhancement (OAE) has been omitted in climate change mitigation scenarios so far. In this study, we provide a techno-economic assessment of large-scale OAE using hydrated lime ('ocean liming'). We address key uncertainties that determine the overall cost of ocean liming (OL) such as the CO2 uptake efficiency per unit of material, distribution strategies avoiding carbonate precipitation which would compromise efficiency, and technology availability (e.g., solar calciners). We find that at economic costs of 130-295 \$/tCO2 net-removed, ocean liming could be a competitive CDR option which could make a significant contribution towards the Paris climate target. As the techno-economic assessment identified no showstoppers, we argue for more research on ecosystem impacts, governance, monitoring, reporting, and verification, and technology development and assessment to determine whether ocean liming and other OAE should be considered as part of a broader CDR portfolio.},
  language  = {en}
}
@article{Ulična2020,
  author    = {Uličn{\´a}, Lenka},
  title     = {Amulets Found in Bohemian Genizot},
  editor    = {Denz, Rebekka and Rudolf, Gabi},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-470-8},
  doi       = {10.25932/publishup-47095},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-470952},
  pages     = {69 -- 80},
  year      = {2020},
  language  = {en}
}
@article{RomeroBarbosaCoelhoScheiffeleetal.2021,
  author    = {Romero Barbosa, Lu{\´i}s and Coelho, Victor Hugo R. and Scheiffele, Lena M. and Baroni, Gabriele and Ramos Filho, Geraldo M. and Montenegro, Suzana M. G. L. and Das Neves Almeida, Cristiano and Oswald, Sascha},
  title     = {Dynamic groundwater recharge simulations based on cosmic-ray neutron sensing in a tropical wet experimental basin},
  series = {Vadose zone journal : VZJ : advancing critical zone science},
  volume    = {20},
  journal   = {Vadose zone journal : VZJ : advancing critical zone science},
  number    = {4},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {1539-1663},
  doi       = {10.1002/vzj2.20145},
  pages     = {22},
  year      = {2021},
  abstract  = {Although cosmic-ray neutron sensing (CRNS) is probably the most promising noninvasive proximal soil moisture measurement technique at the field scale, its application for hydrological simulations remains underexplored in the literature so far. This study assessed the use of CRNS to inversely calibrate soil hydraulic parameters at the intermediate field scale to simulate the groundwater recharge rates at a daily timescale. The study was conducted for two contrasting hydrological years at the Guaraira experimental basin, Brazil, a 5.84-km(2), a tropical wet and rather flat landscape covered by secondary Atlantic forest. As a consequence of the low altitude and proximity to the equator low neutron count rates could be expected, reducing the precision of CRNS while constituting unexplored and challenging conditions for CRNS applications. Inverse calibration for groundwater recharge rates was used based on CRNS or point-scale soil moisture data. The CRNS-derived retention curve and saturated hydraulic conductivity were consistent with the literature and locally performed slug tests. Simulated groundwater recharge rates ranged from 60 to 470 mm yr(-1), corresponding to 5 and 29\% of rainfall, and correlated well with estimates based on water table fluctuations. In contrast, the estimated results based on inversive point-scale datasets were not in alignment with measured water table fluctuations. The better performance of CRNS-based estimations of field-scale hydrological variables, especially groundwater recharge, demonstrated its clear advantages over traditional invasive point-scale techniques. Finally, the study proved the ability of CRNS as practicable in low altitude, tropical wet areas, thus encouraging its adoption for water resources monitoring and management.},
  language  = {en}
}
@inproceedings{PepplerFeisstSchneideretal.2023,
  author    = {Peppler, Lisa and Feißt, Martin and Schneider, Anna and Apelt, Maja and Schenk, Liane},
  title     = {Beyond one-sided expectations of integration},
  series = {European journal of public health},
  volume    = {33},
  booktitle = {European journal of public health},
  number    = {Supplement 2},
  publisher = {Oxford University Press},
  address   = {London},
  issn      = {1101-1262},
  doi       = {10.1093/eurpub/ckad160.1484},
  pages     = {1},
  year      = {2023},
  abstract  = {Background: Like most countries, Germany is currently recruiting international nurses due to staff shortages. While these are mostly academic, the academisation of nursing in Germany has only just begun. This allows for a broader look at the participation of migrant nurses: How do care teams deal with the fact that immigrant colleagues are theoretically more highly qualified than long-established colleagues? Methods: Case studies were conducted in four inpatient care teams of two hospitals in 2022. Qualitative data include 26 observation protocols, 4 group discussions and 17 guided interviews. These were analysed using the documentary method and validated intersubjectively. Results: Due to current academisation efforts in Germany and the immigration of academised nursing staff from abroad, the areas of activity and responsibility of nursing in Germany are under negotiating pressure. This concerns basic care for example, which in Germany is provided by skilled workers, but in other countries is mostly provided by assistants or relatives. The question of who should provide basic care, whether all nurses or only nursing assistants, documents the struggle between an established and a new understanding of care. In this context, the knowledge and skills of migrant and academicised care workers become a crucial aspect in the struggle for a new professional identity for care in Germany. Conclusions: The specific situation in Germany makes it possible to show the potential for change that international care migration can constitute for destination countries. The far-reaching process of change of German nursing is given a further dimension not only by its academization, but by the immigration of international and academically trained nursing staff, where inclusive or exclusive effects can already be observed. Key messages: The increasing proportion of migrant nurses accelerates the current discussion on nursing in Germany. Conflict areas show up in everyday work of care teams and must be addressed there.},
  language  = {en}
}
@article{GonzalezHauckHerrmannHettihewaetal.2022,
  author    = {Gonz{\´a}lez Hauck, Su{\´e} and Herrmann, Franziska and Hettihewa, Julian A. and Kraft, Dariush and Milas, Max and Springer, Stephanie and Weckner, Franka},
  title     = {Jurisdiction},
  series = {Zeitschrift f{\"u}r ausl{\"a}ndisches {\"o}ffentliches Recht und V{\"o}lkerrecht},
  volume    = {82},
  journal   = {Zeitschrift f{\"u}r ausl{\"a}ndisches {\"o}ffentliches Recht und V{\"o}lkerrecht},
  number    = {2},
  publisher = {C.H. Beck},
  address   = {M{\"u}nchen},
  issn      = {0044-2348},
  doi       = {10.17104/0044-2348-2022-2-289},
  pages     = {289 -- 298},
  year      = {2022},
  language  = {en}
}
@article{McHuronAdamczakArnouldetal.2022,
  author    = {McHuron, Elizabeth A. and Adamczak, Stephanie and Arnould, John P. Y. and Ashe, Erin and Booth, Cormac and Bowen, W. Don and Christiansen, Fredrik and Chudzinska, Magda and Costa, Daniel P. and Fahlman, Andreas and Farmer, Nicholas A. and Fortune, Sarah M. E. and Gallagher, Cara A. and Keen, Kelly A. and Madsen, Peter T. and McMahon, Clive R. and Nabe-Nielsen, Jacob and Noren, Dawn P. and Noren, Shawn R. and Pirotta, Enrico and Rosen, David A. S. and Speakman, Cassie N. and Villegas-Amtmann, Stella and Williams, Rob},
  title     = {Key questions in marine mammal bioenergetics},
  series = {Conservation physiology},
  volume    = {10},
  journal   = {Conservation physiology},
  number    = {1},
  publisher = {Oxford Univ. Press},
  address   = {Oxford},
  issn      = {2051-1434},
  doi       = {10.1093/conphys/coac055},
  pages     = {17},
  year      = {2022},
  abstract  = {Bioenergetic approaches are increasingly used to understand how marine mammal populations could be affected by a changing and disturbed aquatic environment. There remain considerable gaps in our knowledge of marine mammal bioenergetics, which hinder the application of bioenergetic studies to inform policy decisions. We conducted a priority-setting exercise to identify high-priority unanswered questions in marine mammal bioenergetics, with an emphasis on questions relevant to conservation and management. Electronic communication and a virtual workshop were used to solicit and collate potential research questions from the marine mammal bioenergetic community. From a final list of 39 questions, 11 were identified as 'key'questions because they received votes from at least 50\% of survey participants. Key questions included those related to energy intake (prey landscapes, exposure to human activities) and expenditure (field metabolic rate, exposure to human activities, lactation, time-activity budgets), energy allocation priorities, metrics of body condition and relationships with survival and reproductive success and extrapolation of data from one species to another. Existing tools to address key questions include labelled water, animal-borne sensors, mark-resight data from long-term research programs, environmental DNA and unmanned vehicles. Further validation of existing approaches and development of new methodologies are needed to comprehensively address some key questions, particularly for cetaceans. The identification of these key questions can provide a guiding framework to set research priorities, which ultimately may yield more accurate information to inform policies and better conserve marine mammal populations.},
  language  = {en}
}
@inproceedings{PanzerBenderGronau2021,
  author    = {Panzer, Marcel and Bender, Benedict and Gronau, Norbert},
  title     = {Deep reinforcement learning in production planning and control},
  series = {Proceedings of the Conference on Production Systems and Logistics},
  booktitle = {Proceedings of the Conference on Production Systems and Logistics},
  publisher = {Institutionelles Repositorium der Leibniz Universit{\"a}t Hannover},
  address   = {Hannover},
  issn      = {2701-6277},
  doi       = {10.15488/11238},
  pages     = {535 -- 545},
  year      = {2021},
  abstract  = {Increasingly fast development cycles and individualized products pose major challenges for today's smart production systems in times of industry 4.0. The systems must be flexible and continuously adapt to changing conditions while still guaranteeing high throughputs and robustness against external disruptions. Deep rein- forcement learning (RL) algorithms, which already reached impressive success with Google DeepMind's AlphaGo, are increasingly transferred to production systems to meet related requirements. Unlike supervised and unsupervised machine learning techniques, deep RL algorithms learn based on recently collected sensor- and process-data in direct interaction with the environment and are able to perform decisions in real-time. As such, deep RL algorithms seem promising given their potential to provide decision support in complex environments, as production systems, and simultaneously adapt to changing circumstances. While different use-cases for deep RL emerged, a structured overview and integration of findings on their application are missing. To address this gap, this contribution provides a systematic literature review of existing deep RL applications in the field of production planning and control as well as production logistics. From a performance perspective, it became evident that deep RL can beat heuristics significantly in their overall performance and provides superior solutions to various industrial use-cases. Nevertheless, safety and reliability concerns must be overcome before the widespread use of deep RL is possible which presumes more intensive testing of deep RL in real world applications besides the already ongoing intensive simulations.},
  language  = {en}
}
@article{Zielnica2024,
  author    = {Zielnica, Krzystof},
  title     = {Alexander von Humboldt und Polen - zum 150. Jahrestag seiner Reise nach Warschau},
  series = {HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies},
  volume    = {XXV},
  journal   = {HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies},
  number    = {48},
  editor    = {Ette, Ottmar and Knobloch, Eberhard},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  issn      = {2568-3543},
  doi       = {10.18443/368},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-646635},
  pages     = {87 -- 101},
  year      = {2024},
  abstract  = {Zuerst erschienen in: Alexander von Humboldt-Stiftung. Mitteilungen, 5. Jg., Heft 38, Oktober 1980, S. 27-36.},
  language  = {en}
}
@article{Kutzinski2024,
  author    = {Kutzinski, Vera M.},
  title     = {Off-road adventures},
  series = {HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies},
  volume    = {XXV},
  journal   = {HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies},
  number    = {48},
  editor    = {Ette, Ottmar and Knobloch, Eberhard},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  issn      = {2568-3543},
  doi       = {10.18443/367},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-646601},
  pages     = {65 -- 86},
  year      = {2024},
  abstract  = {This article focuses on the visual qualities of Alexander von Humboldt's statistical tables in his Political Essay on the Kingdom of New Spain (1808-1811, 2nd ed. 1825-1827) with special attention to how such composites of numbers, alphabetical script, and semiotic elements relate to narrative writing. I argue that Humboldt's tables/tableaus open up spaces inside his narrative that fragment the reading process, inviting new conversations, connections, and ideas.},
  language  = {en}
}
@article{KretzschmarAshbyFearonetal.2022,
  author    = {Kretzschmar, Mirjam E. and Ashby, Ben and Fearon, Elizabeth and Overton, Christopher E. and Panovska-Griffiths, Jasmina and Pellis, Lorenzo and Quaife, Matthew and Rozhnova, Ganna and Scarabel, Francesca and Stage, Helena B. and Swallow, Ben and Thompson, Robin N. and Tildesley, Michael J. and Villela, Daniel Campos},
  title     = {Challenges for modelling interventions for future pandemics},
  series = {Epidemics},
  volume    = {38},
  journal   = {Epidemics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1755-4365},
  doi       = {10.1016/j.epidem.2022.100546},
  pages     = {13},
  year      = {2022},
  abstract  = {Mathematical modelling and statistical inference provide a framework to evaluate different non-pharmaceutical and pharmaceutical interventions for the control of epidemics that has been widely used during the COVID-19 pandemic. In this paper, lessons learned from this and previous epidemics are used to highlight the challenges for future pandemic control. We consider the availability and use of data, as well as the need for correct parameterisation and calibration for different model frameworks. We discuss challenges that arise in describing and distinguishing between different interventions, within different modelling structures, and allowing both within and between host dynamics. We also highlight challenges in modelling the health economic and political aspects of interventions. Given the diversity of these challenges, a broad variety of interdisciplinary expertise is needed to address them, combining mathematical knowledge with biological and social insights, and including health economics and communication skills. Addressing these challenges for the future requires strong cross disciplinary collaboration together with close communication between scientists and policy makers.},
  language  = {en}
}
@article{SeroussiNowickiSimonetal.2019,
  author    = {Seroussi, Helene and Nowicki, Sophie and Simon, Erika and Abe-Ouchi, Ayako and Albrecht, Torsten and Brondex, Julien and Cornford, Stephen and Dumas, Christophe and Gillet-Chaulet, Fabien and Goelzer, Heiko and Golledge, Nicholas R. and Gregory, Jonathan M. and Greve, Ralf and Hoffman, Matthew J. and Humbert, Angelika and Huybrechts, Philippe and Kleiner, Thomas and Larourl, Eric and Leguy, Gunter and Lipscomb, William H. and Lowry, Daniel and Mengel, Matthias and Morlighem, Mathieu and Pattyn, Frank and Payne, Anthony J. and Pollard, David and Price, Stephen F. and Quiquet, Aurelien and Reerink, Thomas J. and Reese, Ronja and Rodehacke, Christian B. and Schlegel, Nicole-Jeanne and Shepherd, Andrew and Sun, Sainan and Sutter, Johannes and Van Breedam, Jonas and van de Wal, Roderik S. W. and Winkelmann, Ricarda and Zhang, Tong},
  title     = {initMIP-Antarctica},
  series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  volume    = {13},
  journal   = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  number    = {5},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-13-1441-2019},
  pages     = {1441 -- 1471},
  year      = {2019},
  abstract  = {Ice sheet numerical modeling is an important tool to estimate the dynamic contribution of the Antarctic ice sheet to sea level rise over the coming centuries. The influence of initial conditions on ice sheet model simulations, however, is still unclear. To better understand this influence, an initial state intercomparison exercise (initMIP) has been developed to compare, evaluate, and improve initialization procedures and estimate their impact on century-scale simulations. initMlP is the first set of experiments of the Ice Sheet Model Intercomparison Project for CMIP6 (ISMIP6), which is the primary Coupled Model Intercomparison Project Phase 6 (CMIP6) activity focusing on the Greenland and Antarctic ice sheets. Following initMlP-Greenland, initMlP-Antarctica has been designed to explore uncertainties associated with model initialization and spin-up and to evaluate the impact of changes in external forcings. Starting from the state of the Antarctic ice sheet at the end of the initialization procedure, three forward experiments are each run for 100 years: a control run, a run with a surface mass balance anomaly, and a run with a basal melting anomaly beneath floating ice. This study presents the results of initMlP-Antarctica from 25 simulations performed by 16 international modeling groups. The submitted results use different initial conditions and initialization methods, as well as ice flow model parameters and reference external forcings. We find a good agreement among model responses to the surface mass balance anomaly but large variations in responses to the basal melting anomaly. These variations can be attributed to differences in the extent of ice shelves and their upstream tributaries, the numerical treatment of grounding line, and the initial ocean conditions applied, suggesting that ongoing efforts to better represent ice shelves in continental-scale models should continue.},
  language  = {en}
}
@article{ReeseAlbrechtMengeletal.2018,
  author    = {Reese, Ronja and Albrecht, Torsten and Mengel, Matthias and Asay-Davis, Xylar and Winkelmann, Ricarda},
  title     = {Antarctic sub-shelf melt rates via PICO},
  series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  volume    = {12},
  journal   = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  number    = {6},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-12-1969-2018},
  pages     = {1969 -- 1985},
  year      = {2018},
  abstract  = {Ocean-induced melting below ice shelves is one of the dominant drivers for mass loss from the Antarctic Ice Sheet at present. An appropriate representation of sub-shelf melt rates is therefore essential for model simulations of marine-based ice sheet evolution. Continental-scale ice sheet models often rely on simple melt-parameterizations, in particular for long-term simulations, when fully coupled ice-ocean interaction becomes computationally too expensive. Such parameterizations can account for the influence of the local depth of the ice-shelf draft or its slope on melting. However, they do not capture the effect of ocean circulation underneath the ice shelf. Here we present the Potsdam Ice-shelf Cavity mOdel (PICO), which simulates the vertical overturning circulation in ice-shelf cavities and thus enables the computation of sub-shelf melt rates consistent with this circulation. PICO is based on an ocean box model that coarsely resolves ice shelf cavities and uses a boundary layer melt formulation. We implement it as a module of the Parallel Ice Sheet Model (PISM) and evaluate its performance under present-day conditions of the Southern Ocean. We identify a set of parameters that yield two-dimensional melt rate fields that qualitatively reproduce the typical pattern of comparably high melting near the grounding line and lower melting or refreezing towards the calving front. PICO captures the wide range of melt rates observed for Antarctic ice shelves, with an average of about 0.1 ma(-1) for cold sub-shelf cavities, for example, underneath Ross or Ronne ice shelves, to 16 ma(-1) for warm cavities such as in the Amundsen Sea region. This makes PICO a computationally feasible and more physical alternative to melt parameterizations purely based on ice draft geometry.},
  language  = {en}
}
@article{ReeseWinkelmannGudmundsson2018,
  author    = {Reese, Ronja and Winkelmann, Ricarda and Gudmundsson, Gudmundur Hilmar},
  title     = {Grounding-line flux formula applied as a flux condition in numerical simulations fails for buttressed Antarctic ice streams},
  series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  volume    = {12},
  journal   = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  number    = {10},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-12-3229-2018},
  pages     = {3229 -- 3242},
  year      = {2018},
  abstract  = {Currently, several large-scale ice-flow models impose a condition on ice flux across grounding lines using an analytically motivated parameterisation of grounding-line flux. It has been suggested that employing this analytical expression alleviates the need for highly resolved computational domains around grounding lines of marine ice sheets. While the analytical flux formula is expected to be accurate in an unbuttressed flow-line setting, its validity has hitherto not been assessed for complex and realistic geometries such as those of the Antarctic Ice Sheet. Here the accuracy of this analytical flux formula is tested against an optimised ice flow model that uses a highly resolved computational mesh around the Antarctic grounding lines. We find that when applied to the Antarctic Ice Sheet the analytical expression provides inaccurate estimates of ice fluxes for almost all grounding lines. Furthermore, in many instances direct application of the analytical formula gives rise to unphysical complex-valued ice fluxes. We conclude that grounding lines of the Antarctic Ice Sheet are, in general, too highly buttressed for the analytical parameterisation to be of practical value for the calculation of grounding-line fluxes.},
  language  = {en}
}
@article{CiemerRehmKurthsetal.2020,
  author    = {Ciemer, Catrin and Rehm, Lars and Kurths, J{\"u}rgen and Donner, Reik Volker and Winkelmann, Ricarda and Boers, Niklas},
  title     = {An early-warning indicator for Amazon droughts exclusively based on tropical Atlantic sea surface temperatures},
  series = {Environmental Research Letters},
  volume    = {15},
  journal   = {Environmental Research Letters},
  number    = {9},
  publisher = {IOP - Institute of Physics Publishing},
  address   = {Bristol},
  pages     = {10},
  year      = {2020},
  abstract  = {Droughts in tropical South America have an imminent and severe impact on the Amazon rainforest and affect the livelihoods of millions of people. Extremely dry conditions in Amazonia have been previously linked to sea surface temperature (SST) anomalies in the adjacent tropical oceans. Although the sources and impacts of such droughts have been widely studied, establishing reliable multi-year lead statistical forecasts of their occurrence is still an ongoing challenge. Here, we further investigate the relationship between SST and rainfall anomalies using a complex network approach. We identify four ocean regions which exhibit the strongest overall SST correlations with central Amazon rainfall, including two particularly prominent regions in the northern and southern tropical Atlantic. Based on the time-dependent correlation between SST anomalies in these two regions alone, we establish a new early-warning method for droughts in the central Amazon basin and demonstrate its robustness in hindcasting past major drought events with lead-times up to 18 months.},
  language  = {en}
}
@article{SeroussiNowickiPayneetal.2020,
  author    = {Seroussi, Helene and Nowicki, Sophie and Payne, Antony J. and Goelzer, Heiko and Lipscomb, William H. and Abe-Ouchi, Ayako and Agosta, Cecile and Albrecht, Torsten and Asay-Davis, Xylar and Barthel, Alice and Calov, Reinhard and Cullather, Richard and Dumas, Christophe and Galton-Fenzi, Benjamin K. and Gladstone, Rupert and Golledge, Nicholas R. and Gregory, Jonathan M. and Greve, Ralf and Hattermann, Tore and Hoffman, Matthew J. and Humbert, Angelika and Huybrechts, Philippe and Jourdain, Nicolas C. and Kleiner, Thomas and Larour, Eric and Leguy, Gunter R. and Lowry, Daniel P. and Little, Chistopher M. and Morlighem, Mathieu and Pattyn, Frank and Pelle, Tyler and Price, Stephen F. and Quiquet, Aurelien and Reese, Ronja and Schlegel, Nicole-Jeanne and Shepherd, Andrew and Simon, Erika and Smith, Robin S. and Straneo, Fiammetta and Sun, Sainan and Trusel, Luke D. and Van Breedam, Jonas and van de Wal, Roderik S. W. and Winkelmann, Ricarda and Zhao, Chen and Zhang, Tong and Zwinger, Thomas},
  title     = {ISMIP6 Antarctica},
  series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  volume    = {14},
  journal   = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  number    = {9},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-14-3033-2020},
  pages     = {3033 -- 3070},
  year      = {2020},
  abstract  = {Ice flow models of the Antarctic ice sheet are commonly used to simulate its future evolution in response to different climate scenarios and assess the mass loss that would contribute to future sea level rise. However, there is currently no consensus on estimates of the future mass balance of the ice sheet, primarily because of differences in the representation of physical processes, forcings employed and initial states of ice sheet models. This study presents results from ice flow model simulations from 13 international groups focusing on the evolution of the Antarctic ice sheet during the period 2015-2100 as part of the Ice Sheet Model Intercomparison for CMIP6 (ISMIP6). They are forced with outputs from a subset of models from the Coupled Model Intercomparison Project Phase 5 (CMIP5), representative of the spread in climate model results. Simulations of the Antarctic ice sheet contribution to sea level rise in response to increased warming during this period varies between 7:8 and 30.0 cm of sea level equivalent (SLE) under Representative Concentration Pathway (RCP) 8.5 scenario forcing. These numbers are relative to a control experiment with constant climate conditions and should therefore be added to the mass loss contribution under climate conditions similar to present-day conditions over the same period. The simulated evolution of the West Antarctic ice sheet varies widely among models, with an overall mass loss, up to 18.0 cm SLE, in response to changes in oceanic conditions. East Antarctica mass change varies between 6 :1 and 8.3 cm SLE in the simulations, with a significant increase in surface mass balance outweighing the increased ice discharge under most RCP 8.5 scenario forcings. The inclusion of ice shelf collapse, here assumed to be caused by large amounts of liquid water ponding at the surface of ice shelves, yields an additional simulated mass loss of 28mm compared to simulations without ice shelf collapse. The largest sources of uncertainty come from the climate forcing, the ocean-induced melt rates, the calibration of these melt rates based on oceanic conditions taken outside of ice shelf cavities and the ice sheet dynamic response to these oceanic changes. Results under RCP 2.6 scenario based on two CMIP5 climate models show an additional mass loss of 0 and 3 cm of SLE on average compared to simulations done under present-day conditions for the two CMIP5 forcings used and display limited mass gain in East Antarctica.},
  language  = {en}
}
@article{ReeseLevermannAlbrechtetal.2020,
  author    = {Reese, Ronja and Levermann, Anders and Albrecht, Torsten and Seroussi, Helene and Winkelmann, Ricarda},
  title     = {The role of history and strength of the oceanic forcing in sea level projections from Antarctica with the Parallel Ice Sheet Model},
  series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  volume    = {14},
  journal   = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  number    = {9},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-14-3097-2020},
  pages     = {3097 -- 3110},
  year      = {2020},
  abstract  = {Mass loss from the Antarctic Ice Sheet constitutes the largest uncertainty in projections of future sea level rise. Ocean-driven melting underneath the floating ice shelves and subsequent acceleration of the inland ice streams are the major reasons for currently observed mass loss from Antarctica and are expected to become more important in the future. Here we show that for projections of future mass loss from the Antarctic Ice Sheet, it is essential (1) to better constrain the sensitivity of sub-shelf melt rates to ocean warming and (2) to include the historic trajectory of the ice sheet. In particular, we find that while the ice sheet response in simulations using the Parallel Ice Sheet Model is comparable to the median response of models in three Antarctic Ice Sheet Intercomparison projects - initMIP, LARMIP-2 and ISMIP6 - conducted with a range of ice sheet models, the projected 21st century sea level contribution differs significantly depending on these two factors. For the highest emission scenario RCP8.5, this leads to projected ice loss ranging from 1:4 to 4:0 cm of sea level equivalent in simulations in which ISMIP6 ocean forcing drives the PICO ocean box model where parameter tuning leads to a comparably low sub-shelf melt sensitivity and in which no surface forcing is applied. This is opposed to a likely range of 9:1 to 35:8 cm using the exact same initial setup, but emulated from the LARMIP-2 experiments with a higher melt sensitivity, even though both projects use forcing from climate models and melt rates are calibrated with previous oceanographic studies. Furthermore, using two initial states, one with a previous historic simulation from 1850 to 2014 and one starting from a steady state, we show that while differences between the ice sheet configurations in 2015 seem marginal at first sight, the historic simulation increases the susceptibility of the ice sheet to ocean warming, thereby increasing mass loss from 2015 to 2100 by 5\% to 50 \%. Hindcasting past ice sheet changes with numerical models would thus provide valuable tools to better constrain projections. Our results emphasize that the uncertainty that arises from the forcing is of the same order of magnitude as the ice dynamic response for future sea level projections.},
  language  = {en}
}
@article{ZeitzLevermannWinkelmann2020,
  author    = {Zeitz, Maria and Levermann, Anders and Winkelmann, Ricarda},
  title     = {Sensitivity of ice loss to uncertainty in flow law parameters in an idealized one-dimensional geometry},
  series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  volume    = {14},
  journal   = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  number    = {10},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-14-3537-2020},
  pages     = {3537 -- 3550},
  year      = {2020},
  abstract  = {Acceleration of the flow of ice drives mass losses in both the Antarctic and the Greenland Ice Sheet. The projections of possible future sea-level rise rely on numerical ice-sheet models, which solve the physics of ice flow, melt, and calving. While major advancements have been made by the ice-sheet modeling community in addressing several of the related uncertainties, the flow law, which is at the center of most process-based ice-sheet models, is not in the focus of the current scientific debate. However, recent studies show that the flow law parameters are highly uncertain and might be different from the widely accepted standard values. Here, we use an idealized flow-line setup to investigate how these uncertainties in the flow law translate into uncertainties in flow-driven mass loss. In order to disentangle the effect of future warming on the ice flow from other effects, we perform a suite of experiments with the Parallel Ice Sheet Model (PISM), deliberately excluding changes in the surface mass balance. We find that changes in the flow parameters within the observed range can lead up to a doubling of the flow-driven mass loss within the first centuries of warming, compared to standard parameters. The spread of ice loss due to the uncertainty in flow parameters is on the same order of magnitude as the increase in mass loss due to surface warming. While this study focuses on an idealized flow-line geometry, it is likely that this uncertainty carries over to realistic three-dimensional simulations of Greenland and Antarctica.},
  language  = {en}
}
@article{AlbrechtWinkelmannLevermann2020,
  author    = {Albrecht, Torsten and Winkelmann, Ricarda and Levermann, Anders},
  title     = {Glacial-cycle simulations of the Antarctic Ice Sheet with the Parallel Ice Sheet Model (PISM)},
  series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  volume    = {14},
  journal   = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  number    = {2},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-14-599-2020},
  pages     = {599 -- 632},
  year      = {2020},
  abstract  = {Simulations of the glacial-interglacial history of the Antarctic Ice Sheet provide insights into dynamic threshold behavior and estimates of the ice sheet's contributions to global sea-level changes for the past, present and future. However, boundary conditions are weakly constrained, in particular at the interface of the ice sheet and the bedrock. Also climatic forcing covering the last glacial cycles is uncertain, as it is based on sparse proxy data. <br /> We use the Parallel Ice Sheet Model (PISM) to investigate the dynamic effects of different choices of input data, e.g., for modern basal heat flux or reconstructions of past changes of sea level and surface temperature. As computational resources are limited, glacial-cycle simulations are performed using a comparably coarse model grid of 16 km and various parameterizations, e.g., for basal sliding, iceberg calving, or for past variations in precipitation and ocean temperatures. In this study we evaluate the model's transient sensitivity to corresponding parameter choices and to different boundary conditions over the last two glacial cycles and provide estimates of involved uncertainties. We also discuss isolated and combined effects of climate and sea-level forcing. Hence, this study serves as a "cookbook" for the growing community of PISM users and paleo-ice sheet modelers in general. <br /> For each of the different model uncertainties with regard to climatic forcing, ice and Earth dynamics, and basal processes, we select one representative model parameter that captures relevant uncertainties and motivates corresponding parameter ranges that bound the observed ice volume at present. The four selected parameters are systematically varied in a parameter ensemble analysis, which is described in a companion paper.},
  language  = {en}
}
@article{KreuzerReeseHuiskampetal.2021,
  author    = {Kreuzer, Moritz and Reese, Ronja and Huiskamp, Willem Nicholas and Petri, Stefan and Albrecht, Torsten and Feulner, Georg and Winkelmann, Ricarda},
  title     = {Coupling framework (1.0) for the PISM (1.1.4) ice sheet model and the MOMS (5.1.0) ocean model via the PICO ice shelf cavity model in an Antarctic domain},
  series = {Geoscientific model development : an interactive open access journal of the European Geosciences Union},
  volume    = {14},
  journal   = {Geoscientific model development : an interactive open access journal of the European Geosciences Union},
  number    = {6},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1991-959X},
  doi       = {10.5194/gmd-14-3697-2021},
  pages     = {3697 -- 3714},
  year      = {2021},
  abstract  = {The past and future evolution of the Antarctic Ice Sheet is largely controlled by interactions between the ocean and floating ice shelves. To investigate these interactions, coupled ocean and ice sheet model configurations are required. Previous modelling studies have mostly relied on high-resolution configurations, limiting these studies to individual glaciers or regions over short timescales of decades to a few centuries. We present a framework to couple the dynamic ice sheet model PISM (Parallel Ice Sheet Model) with the global ocean general circulation model MOM5 (Modular Ocean Model) via the ice shelf cavity model PICO (Pots-dam Ice-shelf Cavity mOdel). As ice shelf cavities are not resolved by MOM5 but are parameterized with the PICO box model, the framework allows the ice sheet and ocean components to be run at resolutions of 16 km and 3 degrees respectively. This approach makes the coupled configuration a useful tool for the analysis of interactions between the Antarctic Ice Sheet and the global ocean over time spans of the order of centuries to millennia. In this study, we describe the technical implementation of this coupling framework: sub-shelf melting in the ice sheet component is calculated by PICO from modelled ocean temperatures and salinities at the depth of the continental shelf, and, vice versa, the resulting mass and energy fluxes from melting at the ice-ocean interface are transferred to the ocean component. Mass and energy fluxes are shown to be conserved to machine precision across the considered component domains. The implementation is computationally efficient as it introduces only minimal overhead. Furthermore, the coupled model is evaluated in a 4000 year simulation under constant present-day climate forcing and is found to be stable with respect to the ocean and ice sheet spin-up states. The framework deals with heterogeneous spatial grid geometries, varying grid resolutions, and timescales between the ice and ocean component in a generic way; thus, it can be adopted to a wide range of model set-ups.},
  language  = {en}
}
@article{ZeitzHaackerDongesetal.2022,
  author    = {Zeitz, Maria and Haacker, Jan M. and Donges, Jonathan and Albrecht, Torsten and Winkelmann, Ricarda},
  title     = {Dynamic regimes of the Greenland Ice Sheet emerging from interacting melt-elevation and glacial isostatic adjustment feedbacks},
  series = {Earth system dynamics},
  volume    = {13},
  journal   = {Earth system dynamics},
  number    = {3},
  publisher = {Copernicus Publ.},
  address   = {G{\"o}ttingen},
  issn      = {2190-4979},
  doi       = {10.5194/esd-13-1077-2022},
  pages     = {1077 -- 1096},
  year      = {2022},
  abstract  = {The stability of the Greenland Ice Sheet under global warming is governed by a number of dynamic processes and interacting feedback mechanisms in the ice sheet, atmosphere and solid Earth. Here we study the long-term effects due to the interplay of the competing melt-elevation and glacial isostatic adjustment (GIA) feedbacks for different temperature step forcing experiments with a coupled ice-sheet and solid-Earth model. Our model results show that for warming levels above 2 degrees C, Greenland could become essentially ice-free within several millennia, mainly as a result of surface melting and acceleration of ice flow. These ice losses are mitigated, however, in some cases with strong GIA feedback even promoting an incomplete recovery of the Greenland ice volume. We further explore the full-factorial parameter space determining the relative strengths of the two feedbacks: our findings suggest distinct dynamic regimes of the Greenland Ice Sheets on the route to destabilization under global warming - from incomplete recovery, via quasi-periodic oscillations in ice volume to ice-sheet collapse. In the incomplete recovery regime, the initial ice loss due to warming is essentially reversed within 50 000 years, and the ice volume stabilizes at 61 \%-93 \% of the present-day volume. For certain combinations of temperature increase, atmospheric lapse rate and mantle viscosity, the interaction of the GIA feedback and the melt-elevation feedback leads to self-sustained, long-term oscillations in ice-sheet volume with oscillation periods between 74 000 and over 300 000 years and oscillation amplitudes between 15 \%-70 \% of present-day ice volume. This oscillatory regime reveals a possible mode of internal climatic variability in the Earth system on timescales on the order of 100 000 years that may be excited by or synchronized with orbital forcing or interact with glacial cycles and other slow modes of variability. Our findings are not meant as scenario-based near-term projections of ice losses but rather providing insight into of the feedback loops governing the "deep future" and, thus, long-term resilience of the Greenland Ice Sheet.},
  language  = {en}
}
@article{AlbrechtWinkelmannLevermann2020,
  author    = {Albrecht, Torsten and Winkelmann, Ricarda and Levermann, Anders},
  title     = {Glacial-cycle simulations of the Antarctic Ice Sheet with the Parallel Ice Sheet Model (PISM)},
  series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  volume    = {14},
  journal   = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  number    = {2},
  publisher = {Copernicus Publ.},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-14-633-2020},
  pages     = {633 -- 656},
  year      = {2020},
  abstract  = {The Parallel Ice Sheet Model (PISM) is applied to the Antarctic Ice Sheet over the last two glacial cycles (approximate to 210 000 years) with a resolution of 16 km. An ensemble of 256 model runs is analyzed in which four relevant model parameters have been systematically varied using full-factorial parameter sampling. Parameters and plausible parameter ranges have been identified in a companion paper (Albrecht et al., 2020) and are associated with ice dynamics, climatic forcing, basal sliding and bed deformation and represent distinct classes of model uncertainties. The model is scored against both modern and geologic data, including reconstructed grounding-line locations, elevation-age data, ice thickness, surface velocities and uplift rates. An aggregated score is computed for each ensemble member that measures the overall model-data misfit, including measurement uncertainty in terms of a Gaussian error model (Briggs and Tarasov, 2013). The statistical method used to analyze the ensemble simulation results follows closely the simple averaging method described in Pollard et al. (2016). This analysis reveals clusters of best-fit parameter combinations, and hence a likely range of relevant model and boundary parameters, rather than individual best-fit parameters. The ensemble of reconstructed histories of Antarctic Ice Sheet volumes provides a score-weighted likely range of sea-level contributions since the Last Glacial Maximum (LGM) of 9.4 +/- 4.1m (or 6.5 +/- 2.0 x 10(6) km(3)), which is at the upper range of most previous studies. The last deglaciation occurs in all ensemble simulations after around 12 000 years before present and hence after the meltwater pulse 1A (MWP1a). Our ensemble analysis also provides an estimate of parametric uncertainty bounds for the present-day state that can be used for PISM projections of future sea-level contributions from the Antarctic Ice Sheet.},
  language  = {en}
}
@article{SchlemmFeldmannWinkelmannetal.2022,
  author    = {Schlemm, Tanja and Feldmann, Johannes and Winkelmann, Ricarda and Levermann, Anders},
  title     = {Stabilizing effect of melange buttressing on the marine ice-cliff instability of the West Antarctic Ice Sheet},
  series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  volume    = {16},
  journal   = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  number    = {5},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-16-1979-2022},
  pages     = {1979 -- 1996},
  year      = {2022},
  abstract  = {Owing to global warming and particularly high regional ocean warming, both Thwaites and Pine Island Glaciers in the Amundsen region of the Antarctic Ice Sheet could lose their buttressing ice shelves over time. We analyse the possible consequences using the parallel ice sheet model (PISM), applying a simple cliff-calving parameterization and an ice melange-buttressing model. We find that the instantaneous loss of ice-shelf buttressing, due to enforced ice-shelf melting, initiates grounding-line retreat and triggers marine ice sheet instability (MISI). As a consequence, the grounding line progresses into the interior of the West Antarctic Ice Sheet and leads to a sea level contribution of 0.6 m within 100 a. By subjecting the exposed ice cliffs to cliff calving using our simplified parameterization, we also analyse marine ice cliff instability (MICI). In our simulations it can double or even triple the sea level contribution depending on the only loosely constrained parameter that determines the maximum cliff-calving rate. The speed of MICI depends on this upper bound of the calving rate, which is given by the ice melange buttressing the glacier. However, stabilization of MICI may occur for geometric reasons. Because the embayment geometry changes as MICI advances into the interior of the ice sheet, the upper bound on calving rates is reduced and the progress of MICI is slowed down. Although we cannot claim that our simulations bear relevant quantitative estimates of the effect of ice-melange buttressing on MICI, the mechanism has the potential to stop the instability. Further research is needed to evaluate its role for the past and future evolution of the Antarctic Ice Sheet.},
  language  = {en}
}
@article{FeldmannReeseWinkelmannetal.2022,
  author    = {Feldmann, Johannes and Reese, Ronja and Winkelmann, Ricarda and Levermann, Anders},
  title     = {Shear-margin melting causes stronger transient ice discharge than ice-stream melting in idealized simulations},
  series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  volume    = {16},
  journal   = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  number    = {5},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1994-0416},
  doi       = {10.5194/tc-16-1927-2022},
  pages     = {1927 -- 1940},
  year      = {2022},
  abstract  = {Basal ice-shelf melting is the key driver of Antarctica's increasing sea-level contribution. In diminishing the buttressing force of the ice shelves that fringe the ice sheet, the melting increases the ice discharge into the ocean. Here we contrast the influence of basal melting in two different ice-shelf regions on the time-dependent response of an isothermal, inherently buttressed ice-sheet-shelf system. In the idealized numerical simulations, the basal-melt perturbations are applied close to the grounding line in the ice-shelf's (1) ice-stream region, where the ice shelf is fed by the fastest ice masses that stream through the upstream bed trough and (2) shear margins, where the ice flow is slower. The results show that melting below one or both of the shear margins can cause a decadal to centennial increase in ice discharge that is more than twice as large compared to a similar perturbation in the ice-stream region. We attribute this to the fact that melt-induced ice-shelf thinning in the central grounding-line region is attenuated very effectively by the fast flow of the central ice stream. In contrast, the much slower ice dynamics in the lateral shear margins of the ice shelf facilitate sustained ice-shelf thinning and thereby foster buttressing reduction. Regardless of the melt location, a higher melt concentration toward the grounding line generally goes along with a stronger response. Our results highlight the vulnerability of outlet glaciers to basal melting in stagnant, buttressing-relevant ice-shelf regions, a mechanism that may gain importance under future global warming.},
  language  = {en}
}
@article{WunderlingWilleitDongesetal.2020,
  author    = {Wunderling, Nico and Willeit, Matteo and Donges, Jonathan and Winkelmann, Ricarda},
  title     = {Global warming due to loss of large ice masses and Arctic summer sea ice},
  series = {Nature Communications},
  volume    = {11},
  journal   = {Nature Communications},
  number    = {1},
  publisher = {Nature Publishing Group},
  address   = {Berlin},
  issn      = {2041-1723},
  doi       = {10.1038/s41467-020-18934-3},
  pages     = {14},
  year      = {2020},
  abstract  = {Several large-scale cryosphere elements such as the Arctic summer sea ice, the mountain glaciers, the Greenland and West Antarctic Ice Sheet have changed substantially during the last century due to anthropogenic global warming. However, the impacts of their possible future disintegration on global mean temperature (GMT) and climate feedbacks have not yet been comprehensively evaluated. Here, we quantify this response using an Earth system model of intermediate complexity. Overall, we find a median additional global warming of 0.43 degrees C (interquartile range: 0.39-0.46 degrees C) at a CO2 concentration of 400 ppm. Most of this response (55\%) is caused by albedo changes, but lapse rate together with water vapour (30\%) and cloud feedbacks (15\%) also contribute significantly. While a decay of the ice sheets would occur on centennial to millennial time scales, the Arctic might become ice-free during summer within the 21st century. Our findings imply an additional increase of the GMT on intermediate to long time scales. The disintegration of cryosphere elements such as the Arctic summer sea ice, mountain glaciers, Greenland and West Antarctica is associated with temperature and radiative feedbacks. In this work, the authors quantify these feedbacks and find an additional global warming of 0.43 degrees C.},
  language  = {en}
}
@article{DurandvandenBroekeLeCozannetetal.2022,
  author    = {Durand, Gael and van den Broeke, Michiel R. and Le Cozannet, Goneri and Edwards, Tamsin L. and Holland, Paul R. and Jourdain, Nicolas C. and Marzeion, Ben and Mottram, Ruth and Nicholls, Robert J. and Pattyn, Frank and Paul, Frank and Slangen, Aimee B. A. and Winkelmann, Ricarda and Burgard, Clara and van Calcar, Caroline J. and Barre, Jean-Baptiste and Bataille, Amelie and Chapuis, Anne},
  title     = {Sea-Level rise: from global perspectives to local services},
  series = {Frontiers in Marine Science},
  volume    = {8},
  journal   = {Frontiers in Marine Science},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-7745},
  doi       = {10.3389/fmars.2021.709595},
  pages     = {8},
  year      = {2022},
  abstract  = {Coastal areas are highly diverse, ecologically rich, regions of key socio-economic activity, and are particularly sensitive to sea-level change. Over most of the 20th century, global mean sea level has risen mainly due to warming and subsequent expansion of the upper ocean layers as well as the melting of glaciers and ice caps. Over the last three decades, increased mass loss of the Greenland and Antarctic ice sheets has also started to contribute significantly to contemporary sea-level rise. The future mass loss of the two ice sheets, which combined represent a sea-level rise potential of similar to 65 m, constitutes the main source of uncertainty in long-term (centennial to millennial) sea-level rise projections. Improved knowledge of the magnitude and rate of future sea-level change is therefore of utmost importance. Moreover, sea level does not change uniformly across the globe and can differ greatly at both regional and local scales. The most appropriate and feasible sea level mitigation and adaptation measures in coastal regions strongly depend on local land use and associated risk aversion. Here, we advocate that addressing the problem of future sea-level rise and its impacts requires (i) bringing together a transdisciplinary scientific community, from climate and cryospheric scientists to coastal impact specialists, and (ii) interacting closely and iteratively with users and local stakeholders to co-design and co-build coastal climate services, including addressing the high-end risks.},
  language  = {en}
}
@article{ZeitzReeseBeckmannetal.2021,
  author    = {Zeitz, Maria and Reese, Ronja and Beckmann, Johanna and Krebs-Kanzow, Uta and Winkelmann, Ricarda},
  title     = {Impact of the melt-albedo feedback on the future evolution of the Greenland Ice Sheet with PISM-dEBM-simple},
  series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  volume    = {15},
  journal   = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union},
  number    = {12},
  publisher = {Copernicus},
  address   = {Katlenburg-Lindau},
  issn      = {1994-0416},
  doi       = {10.5194/tc-15-5739-2021},
  pages     = {5739 -- 5764},
  year      = {2021},
  abstract  = {Surface melting of the Greenland Ice Sheet contributes a large amount to current and future sea level rise. Increased surface melt may lower the reflectivity of the ice sheet surface and thereby increase melt rates: the so-called melt-albedo feedback describes this self-sustaining increase in surface melting. In order to test the effect of the melt-albedo feedback in a prognostic ice sheet model, we implement dEBM-simple, a simplified version of the diurnal Energy Balance Model dEBM, in the Parallel Ice Sheet Model (PISM). The implementation includes a simple representation of the melt-albedo feedback and can thereby replace the positive-degree-day melt scheme. Using PISM-dEBM-simple, we find that this feedback increases ice loss through surface warming by 60 \% until 2300 for the high-emission scenario RCP8.5 when compared to a scenario in which the albedo remains constant at its present-day values. With an increase of 90 \% compared to a fixed-albedo scenario, the effect is more pronounced for lower surface warming under RCP2.6. Furthermore, assuming an immediate darkening of the ice surface over all summer months, we estimate an upper bound for this effect to be 70 \% in the RCP8.5 scenario and a more than 4-fold increase under RCP2.6. With dEBM-simple implemented in PISM, we find that the melt-albedo feedback is an essential contributor to mass loss in dynamic simulations of the Greenland Ice Sheet under future warming.},
  language  = {en}
}
@article{KloseWunderlingWinkelmannetal.2021,
  author    = {Klose, Ann Kristin and Wunderling, Nico and Winkelmann, Ricarda and Donges, Jonathan},
  title     = {What do we mean, 'tipping cascade'?},
  series = {Environmental research letters : ERL},
  volume    = {16},
  journal   = {Environmental research letters : ERL},
  number    = {12},
  publisher = {IOP Publ. Ltd.},
  address   = {Bristol},
  issn      = {1748-9326},
  doi       = {10.1088/1748-9326/ac3955},
  pages     = {11},
  year      = {2021},
  abstract  = {Based on suggested interactions of potential tipping elements in the Earth's climate and in ecological systems, tipping cascades as possible dynamics are increasingly discussed and studied. The activation of such tipping cascades would impose a considerable risk for human societies and biosphere integrity. However, there are ambiguities in the description of tipping cascades within the literature so far. Here we illustrate how different patterns of multiple tipping dynamics emerge from a very simple coupling of two previously studied idealized tipping elements. In particular, we distinguish between a two phase cascade, a domino cascade and a joint cascade. A mitigation of an unfolding two phase cascade may be possible and common early warning indicators are sensitive to upcoming critical transitions to a certain degree. In contrast, a domino cascade may hardly be stopped once initiated and critical slowing down-based indicators fail to indicate tipping of the following element. These different potentials for intervention and anticipation across the distinct patterns of multiple tipping dynamics should be seen as a call to be more precise in future analyses of cascading dynamics arising from tipping element interactions in the Earth system.},
  language  = {en}
}
@article{TiberiusWeyland2023,
  author    = {Tiberius, Victor and Weyland, Michael},
  title     = {Identifying constituent elements of entrepreneurship curricula},
  series = {Administrative sciences},
  volume    = {14},
  journal   = {Administrative sciences},
  number    = {1},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2076-3387},
  doi       = {10.3390/admsci14010001},
  pages     = {18},
  year      = {2023},
  abstract  = {Entrepreneurship education research has a strong "output" focus on impact studies but pays much less attention to the "inside" or process perspective of the way entrepreneurship education occurs. In particular, the scattered previous entrepreneurship curriculum research has not managed to provide a current and comprehensive overview of the curricular elements that constitute entrepreneurship education. To overcome this shortcoming, we aim to identify the teaching objectives, teaching contents, teaching methods, and assessment methods discussed in entrepreneurship curriculum research. To this end, we conducted a systematic literature review on the four entrepreneurship curriculum dimensions and collected all mentioned curriculum items. We used a two-stage coding procedure to find the genuinely entrepreneurship-specific items. Among numerous items (also from business management and other subjects), we found 26 objectives, 34 contents, 11 teaching methods, and 7 assessment methods that were entrepreneurship-specific. Most of these items were addressed by only a few scholarly papers.},
  language  = {en}
}