@article{LangaryKuekenNikoloski2023, author = {Langary, Damoun and K{\"u}ken, Anika and Nikoloski, Zoran}, title = {The effective deficiency of biochemical networks}, series = {Scientific reports}, volume = {13}, journal = {Scientific reports}, publisher = {Springer Nature}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-023-41767-1}, pages = {12}, year = {2023}, abstract = {The deficiency of a (bio)chemical reaction network can be conceptually interpreted as a measure of its ability to support exotic dynamical behavior and/or multistationarity. The classical definition of deficiency relates to the capacity of a network to permit variations of the complex formation rate vector at steady state, irrespective of the network kinetics. However, the deficiency is by definition completely insensitive to the fine details of the directionality of reactions as well as bounds on reaction fluxes. While the classical definition of deficiency can be readily applied in the analysis of unconstrained, weakly reversible networks, it only provides an upper bound in the cases where relevant constraints on reaction fluxes are imposed. Here we propose the concept of effective deficiency, which provides a more accurate assessment of the network's capacity to permit steady state variations at the complex level for constrained networks of any reversibility patterns. The effective deficiency relies on the concept of nonstoichiometric balanced complexes, which we have already shown to be present in real-world biochemical networks operating under flux constraints. Our results demonstrate that the effective deficiency of real-world biochemical networks is smaller than the classical deficiency, indicating the effects of reaction directionality and flux bounds on the variation of the complex formation rate vector at steady state.}, language = {en} } @article{SammoudBouguezziUthoffetal.2023, author = {Sammoud, Senda and Bouguezzi, Raja and Uthoff, Aaron and Ramirez-Campillo, Rodrigo and Moran, Jason and Negra, Yassine and Hachana, Younes and Chaabene, Helmi}, title = {The effects of backward vs. forward running training on measures of physical fitness in young female handball players}, series = {Frontiers in sports and active living}, volume = {5}, journal = {Frontiers in sports and active living}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2624-9367}, doi = {10.3389/fspor.2023.1244369}, pages = {10}, year = {2023}, abstract = {Introduction This study examined the effects of an 8-week backward running (BR) vs. forward running (FR) training programmes on measures of physical fitness in young female handball players. Methods Twenty-nine players participated in this study. Participants were randomly assigned to a FR training group, BR training group, and a control group. Results and discussion Within-group analysis indicated significant, small-to-large improvements in all performance tests (effect size [g] = 0.36 to 1.80), except 5-m forward sprint-time in the BR group and 5- and 10-m forward sprint-time in the FR group. However, the CG significantly decreased forward sprint performance over 10-m and 20-m (g = 0.28 to 0.50) with no changes in the other fitness parameters. No significant differences in the amount of change scores between the BR and FR groups were noted. Both training interventions have led to similar improvements in measures of muscle power, change of direction (CoD) speed, sprint speed either forward or backward, and repeated sprint ability (RSA) in young female handball players, though BR training may have a small advantage over FR training for 10-m forward sprint time and CoD speed, while FR training may provide small improvements over BR training for RSAbest. Practitioners are advised to consider either FR or BR training to improve various measures of physical fitness in young female handball players.}, language = {en} } @article{QuarmbyZhangGeisleretal.2023, author = {Quarmby, Andrew and Zhang, Martin and Geisler, Moritz and Javorsky, Tomas and Mugele, Hendrik and Cassel, Michael and Lawley, Justin}, title = {Risk factors and injury prevention strategies for overuse injuries in adult climbers}, series = {Frontiers in sports and active living}, volume = {5}, journal = {Frontiers in sports and active living}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2624-9367}, doi = {10.3389/fspor.2023.1269870}, pages = {13}, year = {2023}, abstract = {Introduction Climbing is an increasingly popular activity and imposes specific physiological demands on the human body, which results in unique injury presentations. Of particular concern are overuse injuries (non-traumatic injuries). These injuries tend to present in the upper body and might be preventable with adequate knowledge of risk factors which could inform about injury prevention strategies. Research in this area has recently emerged but has yet to be synthesized comprehensively. Therefore, the aim of this study was to conduct a systematic review of the potential risk factors and injury prevention strategies for overuse injuries in adult climbers. Methods This systematic review was conducted in accordance with the PRISMA guidelines. Databases were searched systematically, and articles were deemed eligible based upon specific criteria. Research included was original and peer-reviewed, involving climbers, and published in English, German or Czech. Outcomes included overuse injury, and at least one or more variable indicating potential risk factors or injury prevention strategies. The methodological quality of the included studies was assessed with the Downs and Black Quality Index. Data were extracted from included studies and reported descriptively for population, climbing sport type, study design, injury definition and incidence/prevalence, risk factors, and injury prevention strategies. Results Out of 1,183 records, a total of 34 studies were included in the final analysis. Higher climbing intensity, bouldering, reduced grip/finger strength, use of a "crimp" grip, and previous injury were associated with an increased risk of overuse injury. Additionally, a strength training intervention prevented shoulder and elbow injuries. BMI/body weight, warm up/cool downs, stretching, taping and hydration were not associated with risk of overuse injury. The evidence for the risk factors of training volume, age/years of climbing experience, and sex was conflicting. Discussion This review presents several risk factors which appear to increase the risk of overuse injury in climbers. Strength and conditioning, load management, and climbing technique could be targeted in injury prevention programs, to enhance the health and wellbeing of climbing athletes. Further research is required to investigate the conflicting findings reported across included studies, and to investigate the effectiveness of injury prevention programs. Systematic Review Registrationhttps://www.crd.york.ac.uk/, PROSPERO (CRD42023404031).}, language = {en} } @article{KellerNotbohmBlochetal.2022, author = {Keller, Sebastian and Notbohm, Hannah Lisa and Bloch, Wilhelm and Schumann, Moritz}, title = {Reduced serum concentrations of reactive oxygen and nitrogen species following strenuous exercise in the heat are not associated with an upregulation in serum antioxidative capacity}, series = {Baltic Journal of Health and Physical Activity}, volume = {14}, journal = {Baltic Journal of Health and Physical Activity}, number = {4}, publisher = {Gda`nsk Academy; Versita, Warsaw}, address = {Gdansk}, issn = {2080-9999}, doi = {10.29359/BJHPA.14.4.03}, pages = {12}, year = {2022}, abstract = {Introduction: Reactive oxygen and nitrogen species (RONS) are produced as a response to exercise and play a part in guiding the adaptive response to physical training. Exercise in the heat has been shown to further increase accumulation of RONS in systemic circulation; however, a high antioxidative response or heat acclimatization mechanisms could attenuate this response. In a previous study, we found reduced RONS concentrations in trained athletes following strenuous cycling in the heat. Therefore, this secondary analysis assessed whether these reduced RONS serum concentrations are induced by an increased serum antioxidant capacity. Methods: Twelve male cyclists (V?O2peak: 60 +/- 4 ml center dot kg-1 center dot min-1) completed a 60-minute constant workload trial (55\% peak power output, ambient temperature 30.4 +/- 0.6 degrees C) with and without ice vest in a randomized order. The core body temperature (Tcore) was measured by an ingestible capsule. Blood samples were collected before and after each trial to determine superoxide dismutase (SOD) and catalase (CAT) activity, total antioxidant capacity (TAC) and RONS. Due to the absence of between-group differences, data of both conditions were pooled. Results: Tcore statistically increased (p < 0.001) over the experimental trials (+6.0 +/- 1.6\%, effect size (ES) = 5.6). Concentrations of RONS (-17.2 +/- 15.5\%, p < 0.001, ES = 1.0) and TAC (-8.9 +/- 22.9\%, p = 0.04, ES = 0.7) statistically decreased, while the activity of CAT (+15.5 +/- 84.0\%, p = 0.90, ES = 0.04) and SOD (+9.2 +/- 58.7\%, p = 0.98, ES = 0.01) remained unchanged. Conclusions: Reduced serum RONS concentrations after strenuous cycling in the heat were not associated with upregulation of serum antioxidant capacity in trained athletes. The prooxidant-antioxidant balance may rather be regulated at a myocellular level and should be further assessed in future studies.}, language = {en} } @article{SteirouGerlitzSunetal.2022, author = {Steirou, Eva and Gerlitz, Lars and Sun, Xun and Apel, Heiko and Agarwal, Ankit and Totz, Sonja Juliana and Merz, Bruno}, title = {Towards seasonal forecasting of flood probabilities in Europe using climate and catchment information}, series = {Scientific reports}, volume = {12}, journal = {Scientific reports}, number = {1}, publisher = {Nature portfolio}, address = {Berlin}, issn = {2045-2322}, doi = {10.1038/s41598-022-16633-1}, pages = {10}, year = {2022}, abstract = {We investigate whether the distribution of maximum seasonal streamflow is significantly affected by catchment or climate state of the season/month ahead. We fit the Generalized Extreme Value (GEV) distribution to extreme seasonal streamflow for around 600 stations across Europe by conditioning the GEV location and scale parameters on 14 indices, which represent the season-ahead climate or catchment state. The comparison of these climate-informed models with the classical GEV distribution, with time-constant parameters, suggests that there is a substantial potential for seasonal forecasting of flood probabilities. The potential varies between seasons and regions. Overall, the season-ahead catchment wetness shows the highest potential, although climate indices based on large-scale atmospheric circulation, sea surface temperature or sea ice concentration also show some skill for certain regions and seasons. Spatially coherent patterns and a substantial fraction of climate-informed models are promising signs towards early alerts to increase flood preparedness already a season ahead.}, language = {en} } @inproceedings{Brinkmann2021, author = {Brinkmann, Maik}, title = {Relevance of public administrations}, series = {Proceedings of the 54th Hawaii International Conference on System Sciences 2021}, booktitle = {Proceedings of the 54th Hawaii International Conference on System Sciences 2021}, publisher = {University of Hawaiʻi at Mānoa}, address = {Honolulu, HI}, isbn = {978-0-9981331-4-0}, doi = {10.24251/HICSS.2021.285}, pages = {10}, year = {2021}, abstract = {Power relations within the area of blockchain governance are complex by definition and a comprehensive analysis that links technological and institutional elements is missing to date. The research that is presented with this article focuses on the visualization of the shifting power relations with the introduction of blockchain. For this purpose, the analysis leverages an adjusted version of the multi-stakeholder influence mapping tool. The analysis considers the various stakeholders within the multi-layered blockchain technology stack and compares three fundamental blockchain scenarios, including public and private blockchain settings. The findings show that public administrations face indeed less power with the introduction of blockchain, while new stakeholders come into play who wield influence rather uncontrolled. Nonetheless, public administrations are not powerless overall and remain influential stakeholders. This paper concludes that blockchain governance is not as democratic as blockchain enthusiasts tend to argue and derives corresponding opportunities for further research.}, language = {en} } @article{Shabbat2021, author = {Shabbat, Maya}, title = {Heimweh}, series = {Quest : issues in contemporary Jewish history}, journal = {Quest : issues in contemporary Jewish history}, number = {20}, publisher = {Fondazione Centro di Documentazione Ebraica Contemporanea}, address = {Milano}, issn = {2037-741X}, doi = {10.48248/issn.2037-741X/13095}, pages = {109 -- 139}, year = {2021}, abstract = {The concept of Heimweh conveys a set of emotions and images that have been described in different ways in different languages. This article intends to analyze the Heimweh experienced by Galician intellectual Jewry during the process of linguistic and cultural change that took place from 1867 until the mid.-1880s. This will be discussed while focusing on the urban intelligentsia circles in Lemberg (Lviv), which had a tremendous influence on some Galician Jewish intellectuals during that period. I will analyze the nature of a clash of identities that eventually brought some of the urban intelligentsia in Lemberg to consider themselves as living a "Spiritual" or "linguistic exile"(Sprachexil), regardless of whether they had migrated or not. Longing for the homeland as a nostalgic destination, whether they referred to it as Heimat or Ojczyzna, and whether they called it Lemberg or Lwow, was longing to be part of a group holding a distinct Kultur or Kultura, a set of values, culture and language, which coexisted with their Jewish identity.}, language = {en} } @misc{Wyrwa2020, author = {Wyrwa, Ulrich}, title = {Rezension zu: Brenner, Michael: Der lange Schatten der Revolution : Juden und Antisemiten in Hitlers M{\"u}nchen 1918 bis 1923. - Berlin: J{\"u}discher Verlag im Suhrkamp Verlag, 2019. - 300 S. - ISBN 978-3-633-54295-6}, series = {Quest : issues in contemporary Jewish history}, journal = {Quest : issues in contemporary Jewish history}, number = {17}, publisher = {Fondazione Centro di Documentazione Ebraica Contemporanea}, address = {Milano}, issn = {2037-741X}, doi = {10.48248/issn.2037-741X/1842}, pages = {222 -- 225}, year = {2020}, language = {en} } @misc{Wyrwa2022, author = {Wyrwa, Ulrich}, title = {Review of: Music for the "Axis". German-Italian music relations under Hitler and Mussolini until 1943}, series = {Quest : issues in contemporary Jewish history}, journal = {Quest : issues in contemporary Jewish history}, number = {22}, publisher = {Fondazione Centro Documentazione Ebraica Contemporanea}, address = {Milano}, issn = {2037-741X}, doi = {10.48248/issn.2037-741X/13762}, pages = {222 -- 225}, year = {2022}, language = {en} } @article{WoodfieldHorneGlauertetal.2018, author = {Woodfield, Emma E. and Horne, Richard B. and Glauert, S. A. and Menietti, J. D. and Shprits, Yuri and Kurth, William S.}, title = {Formation of electron radiation belts at Saturn by Z-mode wave acceleration}, series = {Nature Communications}, volume = {9}, journal = {Nature Communications}, publisher = {Nature Publ. Group}, address = {London}, issn = {2041-1723}, doi = {10.1038/s41467-018-07549-4}, pages = {7}, year = {2018}, abstract = {At Saturn electrons are trapped in the planet's magnetic field and accelerated to relativistic energies to form the radiation belts, but how this dramatic increase in electron energy occurs is still unknown. Until now the mechanism of radial diffusion has been assumed but we show here that in-situ acceleration through wave particle interactions, which initial studies dismissed as ineffectual at Saturn, is in fact a vital part of the energetic particle dynamics there. We present evidence from numerical simulations based on Cassini spacecraft data that a particular plasma wave, known as Z-mode, accelerates electrons to MeV energies inside 4 RS (1 RS = 60,330 km) through a Doppler shifted cyclotron resonant interaction. Our results show that the Z-mode waves observed are not oblique as previously assumed and are much better accelerators than O-mode waves, resulting in an electron energy spectrum that closely approaches observed values without any transport effects included.}, language = {en} }