@article{RischStollSchomoelleretal.2020, author = {Risch, Lucie and Stoll, Josefine and Schom{\"o}ller, Anne and Engel, Tilman and Mayer, Frank and Cassel, Michael}, title = {Intraindividual Doppler Flow Response to Exercise Differs Between Symptomatic and Asymptomatic Achilles Tendons}, series = {Frontiers in physiology}, volume = {12}, journal = {Frontiers in physiology}, publisher = {Frontiers Research Foundation}, address = {Lausanne, Schweiz}, issn = {1664-042X}, doi = {10.3389/fphys.2021.617497}, pages = {1 -- 8}, year = {2020}, abstract = {Objective: This study investigated intraindividual differences of intratendinous blood flow (IBF) in response to running exercise in participants with Achilles tendinopathy. Design: This is a cross-sectional study. Setting: The study was conducted at the University Outpatient Clinic. Participants: Sonographic detectable intratendinous blood flow was examined in symptomatic and contralateral asymptomatic Achilles tendons of 19 participants (42 ± 13 years, 178 ± 10 cm, 76 ± 12 kg, VISA-A 75 ± 16) with clinically diagnosed unilateral Achilles tendinopathy and sonographic evident tendinosis. Intervention: IBF was assessed using Doppler ultrasound "Advanced Dynamic Flow" before (Upre) and 5, 30, 60, and 120 min (U5-U120) after a standardized submaximal constant load run. Main Outcome Measure: IBF was quantified by counting the number (n) of vessels in each tendon. Results: At Upre, IBF was higher in symptomatic compared with asymptomatic tendons [mean 6.3 (95\% CI: 2.8-9.9) and 1.7 (0.4-2.9), p < 0.01]. Overall, 63\% of symptomatic and 47\% of asymptomatic Achilles tendons responded to exercise, whereas 16 and 11\% showed persisting IBF and 21 and 42\% remained avascular throughout the investigation. At U5, IBF increased in both symptomatic and asymptomatic tendons [difference to baseline: 2.4 (0.3-4.5) and 0.9 (0.5-1.4), p = 0.05]. At U30 to U120, IBF was still increased in symptomatic but not in asymptomatic tendons [mean difference to baseline: 1.9 (0.8-2.9) and 0.1 (-0.9 to 1.2), p < 0.01]. Conclusion: Irrespective of pathology, 47-63\% of Achilles tendons responded to exercise with an immediate acute physiological IBF increase by an average of one to two vessels ("responders"). A higher amount of baseline IBF (approximately five vessels) and a prolonged exercise-induced IBF response found in symptomatic ATs indicate a pain-associated altered intratendinous "neovascularization."}, language = {en} } @misc{ValsecchiDimigenKliegletal.2009, author = {Valsecchi, Matteo and Dimigen, Olaf and Kliegl, Reinhold and Sommer, Werner and Turatto, Massimo}, title = {Microsaccadic Inhibition and P300 Enhancement in a Visual Oddball Task}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-57170}, year = {2009}, abstract = {It has recently been demonstrated that the presentation of a rare target in a visual oddball paradigm induces a prolonged inhibition of microsaccades. In the field of electrophysiology, the amplitude of the P300 component in event-related potentials (ERP) has been shown to be sensitive to the stimulus category (target vs. non target) of the eliciting stimulus, its overall probability, and the preceding stimulus sequence. In the present study we further specify the functional underpinnings of the prolonged microsaccadic inhibition in the visual oddball task, showing that the stimulus category, the frequency of a stimulus and the preceding stimulus sequence influence microsaccade rate. Furthermore, by co-recording ERPs and eye-movements, we were able to demonstrate that, despite being largely sensitive to the same experimental manipulation, the amplitude of P300 and the microsaccadic inhibition predict each other very weakly, and thus constitute two independent measures of the brain's response to rare targets in the visual oddball paradigm.}, language = {en} } @misc{BostonHaleKliegletal.2008, author = {Boston, Marisa Ferrara and Hale, John and Kliegl, Reinhold and Patil, Umesh and Vasishth, Shravan}, title = {Parsing costs as predictors of reading difficulty: An evaluation using the Potsdam Sentence Corpus}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-57139}, year = {2008}, abstract = {The surprisal of a word on a probabilistic grammar constitutes a promising complexity metric for human sentence comprehension difficulty. Using two different grammar types, surprisal is shown to have an effect on fixation durations and regression probabilities in a sample of German readers' eye movements, the Potsdam Sentence Corpus. A linear mixed-effects model was used to quantify the effect of surprisal while taking into account unigram and bigram frequency, word length, and empirically-derived word predictability; the so-called "early" and "late" measures of processing difficulty both showed an effect of surprisal. Surprisal is also shown to have a small but statistically non-significant effect on empirically-derived predictability itself. This work thus demonstrates the importance of including parsing costs as a predictor of comprehension difficulty in models of reading, and suggests that a simple identification of syntactic parsing costs with early measures and late measures with durations of post-syntactic events may be difficult to uphold.}, language = {en} } @misc{MingKlieglShuetal.2010, author = {Ming, Yan and Kliegl, Reinhold and Shu, Hua and Pan, Jinger and Zhou, Xiaolin}, title = {Parafoveal Load of Word N+1 Modulates Preprocessing Effectivenessof Word N+2 in Chinese Reading}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-57103}, year = {2010}, abstract = {Preview benefits (PBs) from two words to the right of the fixated one (i.e., word N+2)and associated parafoveal-on-foveal effects are critical for proposals of distributed lexical processing during reading. This experiment examined parafoveal processing during reading of Chinese sentences, using a boundary manipulation of N+2-word preview with low- and high-frequency words N+1. The main findings were (a) an identity PB for word N+2 that was (b) primarily observed when word N+1 was of high frequency (i.e., an interaction between frequency of word N+1 and PB for word N+2), and (c) a parafoveal-on-foveal frequency effect of word N+1 for fixation durations on word N. We discuss implications for theories of serial attention shifts and parallel distributed processing of words during reading.}, language = {en} } @misc{AngeleSlatteryYangetal.2008, author = {Angele, Bernhard and Slattery, Timothy J. and Yang, Jinmian and Kliegl, Reinhold and Rayner, Keith}, title = {Parafoveal processing in reading: Manipulating n+1 and n+2 previews simultaneously}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-57128}, year = {2008}, abstract = {The boundary paradigm (Rayner, 1975) with a novel preview manipulation was used to examine the extent of parafoveal processing of words to the right of fixation. Words n+1 and n+2 had either correct or incorrect previews prior to fixation (prior to crossing the boundary location). In addition, the manipulation utilized either a high or low frequency word in word n+1 location on the assumption that it would be more likely that n+2 preview effects could be obtained when word n+1 was high frequency. The primary findings were that there was no evidence for a preview benefit for word n+2 and no evidence for parafoveal-on-foveal effects when word n+1 is at least four letters long. We discuss implications for models of eye-movement control in reading.}, language = {en} } @misc{BostonHaleVasishthetal.2011, author = {Boston, Marisa Ferrara and Hale, John T. and Vasishth, Shravan and Kliegl, Reinhold}, title = {Parallel processing and sentence comprehension difficulty}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-57159}, year = {2011}, abstract = {Eye fixation durations during normal reading correlate with processing difficulty but the specific cognitive mechanisms reflected in these measures are not well understood. This study finds support in German readers' eyefixations for two distinct difficulty metrics: surprisal, which reflects the change in probabilities across syntactic analyses as new words are integrated, and retrieval, which quantifies comprehension difficulty in terms of working memory constraints. We examine the predictions of both metrics using a family of dependency parsers indexed by an upper limit on the number of candidate syntactic analyses they retain at successive words. Surprisal models all fixation measures and regression probability. By contrast, retrieval does not model any measure in serial processing. As more candidate analyses are considered in parallel at each word, retrieval can account for the same measures as surprisal. This pattern suggests an important role for ranked parallelism in theories of sentence comprehension.}, language = {en} } @article{HeringHauptfleischJagoetal.2022, author = {Hering, Robert and Hauptfleisch, Morgan and Jago, Mark and Smith, Taylor and Kramer-Schadt, Stephanie and Stiegler, Jonas and Blaum, Niels}, title = {Don't stop me now: Managed fence gaps could allow migratory ungulates to track dynamic resources and reduce fence related energy loss}, series = {Frontiers in Ecology and Evolution}, journal = {Frontiers in Ecology and Evolution}, publisher = {Frontiers}, address = {Lausanne, Schweiz}, issn = {2296-701X}, doi = {10.3389/fevo.2022.907079}, pages = {1 -- 18}, year = {2022}, abstract = {In semi-arid environments characterized by erratic rainfall and scattered primary production, migratory movements are a key survival strategy of large herbivores to track resources over vast areas. Veterinary Cordon Fences (VCFs), intended to reduce wildlife-livestock disease transmission, fragment large parts of southern Africa and have limited the movements of large wild mammals for over 60 years. Consequently, wildlife-fence interactions are frequent and often result in perforations of the fence, mainly caused by elephants. Yet, we lack knowledge about at which times fences act as barriers, how fences directly alter the energy expenditure of native herbivores, and what the consequences of impermeability are. We studied 2-year ungulate movements in three common antelopes (springbok, kudu, eland) across a perforated part of Namibia's VCF separating a wildlife reserve and Etosha National Park using GPS telemetry, accelerometer measurements, and satellite imagery. We identified 2905 fence interaction events which we used to evaluate critical times of encounters and direct fence effects on energy expenditure. Using vegetation type-specific greenness dynamics, we quantified what animals gained in terms of high quality food resources from crossing the VCF. Our results show that the perforation of the VCF sustains herbivore-vegetation interactions in the savanna with its scattered resources. Fence permeability led to peaks in crossing numbers during the first flush of woody plants before the rain started. Kudu and eland often showed increased energy expenditure when crossing the fence. Energy expenditure was lowered during the frequent interactions of ungulates standing at the fence. We found no alteration of energy expenditure when springbok immediately found and crossed fence breaches. Our results indicate that constantly open gaps did not affect energy expenditure, while gaps with obstacles increased motion. Closing gaps may have confused ungulates and modified their intended movements. While browsing, sedentary kudu's use of space was less affected by the VCF; migratory, mixed-feeding springbok, and eland benefited from gaps by gaining forage quality and quantity after crossing. This highlights the importance of access to vast areas to allow ungulates to track vital vegetation patches.}, language = {en} } @article{HeroldTheobaldGronwaldetal.2022, author = {Herold, Fabian and Theobald, Paula and Gronwald, Thomas and Rapp, Michael A. and M{\"u}ller, Notger Germar}, title = {Going digital - a commentary on the terminology used at the intersection of physical activity and digital health}, series = {European review of aging and physical activity}, volume = {19}, journal = {European review of aging and physical activity}, publisher = {Springer}, address = {Berlin ; Heidelberg}, issn = {1861-6909}, doi = {10.1186/s11556-022-00296-y}, pages = {7}, year = {2022}, abstract = {In recent years digital technologies have become a major means for providing health-related services and this trend was strongly reinforced by the current Coronavirus disease 2019 (COVID-19) pandemic. As it is well-known that regular physical activity has positive effects on individual physical and mental health and thus is an important prerequisite for healthy aging, digital technologies are also increasingly used to promote unstructured and structured forms of physical activity. However, in the course of this development, several terms (e.g., Digital Health, Electronic Health, Mobile Health, Telehealth, Telemedicine, and Telerehabilitation) have been introduced to refer to the application of digital technologies to provide health-related services such as physical interventions. Unfortunately, the above-mentioned terms are often used in several different ways, but also relatively interchangeably. Given that ambiguous terminology is a major source of difficulty in scientific communication which can impede the progress of theoretical and empirical research, this article aims to make the reader aware of the subtle differences between the relevant terms which are applied at the intersection of physical activity and Digital Health and to provide state-of-art definitions for them.}, language = {en} } @article{PerezChaparroSchuchZechetal.2021, author = {P{\´e}rez Chaparro, Camilo Germ{\´a}n Alberto and Schuch, Felipe Barreto and Zech, Philipp and Kangas, Maria and Rapp, Michael A. and Heißel, Andreas}, title = {Recreational exercising and self-reported cardiometabolic diseases in German people living with HIV}, series = {International journal of environmental research and public health : IJERPH / Molecular Diversity Preservation International}, volume = {18}, journal = {International journal of environmental research and public health : IJERPH / Molecular Diversity Preservation International}, number = {21}, publisher = {MDPI}, address = {Basel, Schweiz}, issn = {1660-4601}, doi = {10.3390/ijerph182111579}, pages = {1 -- 10}, year = {2021}, abstract = {Exercise is known for its beneficial effects on preventing cardiometabolic diseases (CMDs) in the general population. People living with the human immunodeficiency virus (PLWH) are prone to sedentarism, thus raising their already elevated risk of developing CMDs in comparison to individuals without HIV. The aim of this cross-sectional study was to determine if exercise is associated with reduced risk of self-reported CMDs in a German HIV-positive sample (n = 446). Participants completed a self-report survey to assess exercise levels, date of HIV diagnosis, CD4 cell count, antiretroviral therapy, and CMDs. Participants were classified into exercising or sedentary conditions. Generalized linear models with Poisson regression were conducted to assess the prevalence ratio (PR) of PLWH reporting a CMD. Exercising PLWH were less likely to report a heart arrhythmia for every increase in exercise duration (PR: 0.20: 95\% CI: 0.10-0.62, p < 0.01) and diabetes mellitus for every increase in exercise session per week (PR: 0.40: 95\% CI: 0.10-1, p < 0.01). Exercise frequency and duration are associated with a decreased risk of reporting arrhythmia and diabetes mellitus in PLWH. Further studies are needed to elucidate the mechanisms underlying exercise as a protective factor for CMDs in PLWH.}, language = {en} } @misc{YeZhangWarbyetal.2022, author = {Ye, Fangyuan and Zhang, Shuo and Warby, Jonathan and Wu, Jiawei and Gutierrez-Partida, Emilio and Lang, Felix and Shah, Sahil and Saglamkaya, Elifnaz and Sun, Bowen and Zu, Fengshuo and Shoaee, Safa and Wang, Haifeng and Stiller, Burkhard and Neher, Dieter and Zhu, Wei-Hong and Stolterfoht, Martin and Wu, Yongzhen}, title = {Overcoming C₆₀-induced interfacial recombination in inverted perovskite solar cells by electron-transporting carborane}, series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, number = {1317}, issn = {1866-8372}, doi = {10.25932/publishup-58770}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-587705}, pages = {12}, year = {2022}, abstract = {Inverted perovskite solar cells still suffer from significant non-radiative recombination losses at the perovskite surface and across the perovskite/C₆₀ interface, limiting the future development of perovskite-based single- and multi-junction photovoltaics. Therefore, more effective inter- or transport layers are urgently required. To tackle these recombination losses, we introduce ortho-carborane as an interlayer material that has a spherical molecular structure and a three-dimensional aromaticity. Based on a variety of experimental techniques, we show that ortho-carborane decorated with phenylamino groups effectively passivates the perovskite surface and essentially eliminates the non-radiative recombination loss across the perovskite/C₆₀ interface with high thermal stability. We further demonstrate the potential of carborane as an electron transport material, facilitating electron extraction while blocking holes from the interface. The resulting inverted perovskite solar cells deliver a power conversion efficiency of over 23\% with a low non-radiative voltage loss of 110 mV, and retain >97\% of the initial efficiency after 400 h of maximum power point tracking. Overall, the designed carborane based interlayer simultaneously enables passivation, electron-transport and hole-blocking and paves the way toward more efficient and stable perovskite solar cells.}, language = {en} } @article{SchraplauBlockHaeusleretal.2021, author = {Schraplau, Anne and Block, Andrea and H{\"a}usler, Andreas and Wippert, Pia-Maria and Rapp, Michael A. and V{\"o}ller, Heinz and Bonaventura, Klaus and Mayer, Frank}, title = {Mobile diagnostics and consultation for the prevention of the metabolic syndrome and its secondary diseases in Brandenburg—study protocol of a regional prospective cohort study}, series = {Pilot and Feasibility Studies}, volume = {7}, journal = {Pilot and Feasibility Studies}, publisher = {BioMed Central (Springer Nature)}, address = {London}, issn = {2055-5784}, doi = {10.1186/s40814-021-00898-w}, pages = {1 -- 11}, year = {2021}, abstract = {Background The metabolic syndrome (MetS) is a risk cluster for a number of secondary diseases. The implementation of prevention programs requires early detection of individuals at risk. However, access to health care providers is limited in structurally weak regions. Brandenburg, a rural federal state in Germany, has an especially high MetS prevalence and disease burden. This study aims to validate and test the feasibility of a setup for mobile diagnostics of MetS and its secondary diseases, to evaluate the MetS prevalence and its association with moderating factors in Brandenburg and to identify new ways of early prevention, while establishing a "Mobile Brandenburg Cohort" to reveal new causes and risk factors for MetS. Methods In a pilot study, setups for mobile diagnostics of MetS and secondary diseases will be developed and validated. A van will be equipped as an examination room using point-of-care blood analyzers and by mobilizing standard methods. In study part A, these mobile diagnostic units will be placed at different locations in Brandenburg to locally recruit 5000 participants aged 40-70 years. They will be examined for MetS and advice on nutrition and physical activity will be provided. Questionnaires will be used to evaluate sociodemographics, stress perception, and physical activity. In study part B, participants with MetS, but without known secondary diseases, will receive a detailed mobile medical examination, including MetS diagnostics, medical history, clinical examinations, and instrumental diagnostics for internal, cardiovascular, musculoskeletal, and cognitive disorders. Participants will receive advice on nutrition and an exercise program will be demonstrated on site. People unable to participate in these mobile examinations will be interviewed by telephone. If necessary, participants will be referred to general practitioners for further diagnosis. Discussion The mobile diagnostics approach enables early detection of individuals at risk, and their targeted referral to local health care providers. Evaluation of the MetS prevalence, its relation to risk-increasing factors, and the "Mobile Brandenburg Cohort" create a unique database for further longitudinal studies on the implementation of home-based prevention programs to reduce mortality, especially in rural regions. Trial registration German Clinical Trials Register, DRKS00022764; registered 07 October 2020—retrospectively registered.}, language = {en} } @article{HeisselPietrekKangasetal.2023, author = {Heissel, Andreas and Pietrek, Anou F. and Kangas, Maria and Van der Kaap-Deeder, Jolene and Rapp, Michael A.}, title = {The Mediating Role of Rumination in the Relation between Basic Psychological Need Frustration and Depressive Symptoms}, series = {Journal of Clinical Medicine}, volume = {12}, journal = {Journal of Clinical Medicine}, edition = {2}, publisher = {MDPI}, address = {Basel, Schweiz}, issn = {2077-0383}, doi = {10.3390/jcm12020395}, pages = {1 -- 10}, year = {2023}, abstract = {Research within the framework of Basic Psychological Need Theory (BPNT) finds strong associations between basic need frustration and depressive symptoms. This study examined the role of rumination as an underlying mechanism in the association between basic psychological need frustration and depressive symptoms. A cross-sectional sample of N = 221 adults (55.2\% female, mean age = 27.95, range = 18-62, SD = 10.51) completed measures assessing their level of basic psychological need frustration, rumination, and depressive symptoms. Correlational analyses and multiple mediation models were conducted. Brooding partially mediated the relation between need frustration and depressive symptoms. BPNT and Response Styles Theory are compatible and can further advance knowledge about depression vulnerabilities.}, language = {en} } @article{PietrekKangasKliegletal.2022, author = {Pietrek, Anou F. and Kangas, Maria and Kliegl, Reinhold and Rapp, Michael A. and Heinzel, Stephan and Van der Kaap-Deeder, Jolene and Heissel, Andreas}, title = {Basic psychological need satisfaction and frustration in major depressive disorder}, series = {Frontiers in Psychiatry - Mood Disorders}, journal = {Frontiers in Psychiatry - Mood Disorders}, publisher = {Frontiers Media S.A.}, address = {Lausanne, Schweiz}, issn = {1664-0640}, doi = {10.3389/fpsyt.2022.962501}, pages = {1 -- 10}, year = {2022}, abstract = {Basic psychological needs theory postulates that a social environment that satisfies individuals' three basic psychological needs of autonomy, competence, and relatedness leads to optimal growth and well-being. On the other hand, the frustration of these needs is associated with ill-being and depressive symptoms foremost investigated in non-clinical samples; yet, there is a paucity of research on need frustration in clinical samples. Survey data were compared between adult individuals with major depressive disorder (MDD; n = 115; 48.69\% female; 38.46 years, SD = 10.46) with those of a non-depressed comparison sample (n = 201; 53.23\% female; 30.16 years, SD = 12.81). Need profiles were examined with a linear mixed model (LMM). Individuals with depression reported higher levels of frustration and lower levels of satisfaction in relation to the three basic psychological needs when compared to non-depressed adults. The difference between depressed and non-depressed groups was significantly larger for frustration than satisfaction regarding the needs for relatedness and competence. LMM correlation parameters confirmed the expected positive correlation between the three needs. This is the first study showing substantial differences in need-based experiences between depressed and non-depressed adults. The results confirm basic assumptions of the self-determination theory and have preliminary implications in tailoring therapy for depression.}, language = {en} } @article{JaraMunozMelnickLietal.2022, author = {Jara Mu{\~n}oz, Julius and Melnick, Daniel and Li, Shaoyang and Socquet, Anne and Cort{\´e}s-Aranda, Joaqu{\´i}n and Brill, Dominik and Strecker, Manfred}, title = {The cryptic seismic potential of the Pichilemu blind fault in Chile revealed by off-fault geomorphology}, series = {Nature Communications}, volume = {13}, journal = {Nature Communications}, publisher = {Springer Nature}, address = {London}, issn = {2041-1723}, doi = {10.1038/s41467-022-30754-1}, pages = {13}, year = {2022}, abstract = {The first step towards assessing hazards in seismically active regions involves mapping capable faults and estimating their recurrence times. While the mapping of active faults is commonly based on distinct geologic and geomorphic features evident at the surface, mapping blind seismogenic faults is complicated by the absence of on-fault diagnostic features. Here we investigated the Pichilemu Fault in coastal Chile, unknown until it generated a Mw 7.0 earthquake in 2010. The lack of evident surface faulting suggests activity along a partly-hidden blind fault. We used off-fault deformed marine terraces to estimate a fault-slip rate of 0.52 ± 0.04 m/ka, which, when integrated with satellite geodesy suggests a 2.12 ± 0.2 ka recurrence time for Mw~7.0 normal-faulting earthquakes. We propose that extension in the Pichilemu region is associated with stress changes during megathrust earthquakes and accommodated by sporadic slip during upper-plate earthquakes, which has implications for assessing the seismic potential of cryptic faults along convergent margins and elsewhere.}, language = {en} } @book{DenzStellmacherUllrichetal.2023, author = {Denz, Rebekka and Stellmacher, Martha and Ullrich, Rebecca and Benar, Jael Andra and Uličn{\´a}, Lenka and Martini, Annett and Allgaier-Honal, Recha and Abramowicz, Isidoro and Ariel, Neri Y. and St{\"u}rzebecher, Maria and Weinhold, Beate and Singer-Brehm, Elisabeth}, title = {Genisa-Bl{\"a}tter IV}, editor = {Denz, Rebekka and Stellmacher, Martha and Ullrich, Rebecca}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-539-2}, doi = {10.25932/publishup-55535}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-555356}, publisher = {Universit{\"a}t Potsdam}, pages = {162}, year = {2023}, abstract = {Auch wenn Genisot - j{\"u}dische Ablagen nicht mehr verwendeter B{\"u}cher und Kultgegenst{\"a}nde - in der bisherigen historischen Forschung selten beachtet werden, sind sie als Quellen aus origin{\"a}r j{\"u}discher Hand von hoher Bedeutung und k{\"o}nnen unser Verst{\"a}ndnis der Umsetzung von Ritualen im Kontext der lokalen Gemeinde vertiefen. Der Schwerpunkt der ‚Genisa-Bl{\"a}tter IV' liegt auf Fragen nach j{\"u}disch-rituellen Praktiken und ihrer Bedeutung, ihren Objekten und Akteuren. Acht wissenschaftliche und ein essayistischer Beitrag n{\"a}hern sich diesen Themen {\"u}ber konkrete Funde aus Genisot mitteleurop{\"a}ischer j{\"u}discher Gemeinden, von religi{\"o}sen Texten wie dem Fragment einer Torarolle und einem Minhagim-Buch {\"u}ber Personaldokumente bis hin zu Musiknoten und Kleidungsst{\"u}cken.}, language = {de} } @article{FischerWinterFelisattietal.2021, author = {Fischer, Martin H. and Winter, Bodo and Felisatti, Arianna and Myachykov, Andriy and Jeglinski-Mende, Melinda A. and Shaki, Samuel}, title = {More instructions make fewer subtractions}, series = {Frontiers in psychology / Frontiers Research Foundation}, volume = {12}, journal = {Frontiers in psychology / Frontiers Research Foundation}, publisher = {Frontiers Research Foundation}, address = {Lausanne, Schweiz}, issn = {1664-1078}, doi = {10.3389/fpsyg.2021.720616}, pages = {1 -- 3}, year = {2021}, abstract = {Research on problem solving offers insights into how humans process task-related information and which strategies they use (Newell and Simon, 1972; {\"O}llinger et al., 2014). Problem solving can be defined as the search for possible changes in one's mind (Kahneman, 2003). In a recent study, Adams et al. (2021) assessed whether the predominant problem solving strategy when making changes involves adding or subtracting elements. In order to do this, they used several examples of simple problems, such as editing text or making visual patterns symmetrical, either in naturalistic settings or on-line. The essence of the authors' findings is a strong preference to add rather than subtract elements across a diverse range of problems, including the stabilizing of artifacts, creating symmetrical patterns, or editing texts. More specifically, they succeeded in demonstrating that "participants were less likely to identify advantageous subtractive changes when the task did not (vs. did) cue them to consider subtraction, when they had only one opportunity (vs. several) to recognize the shortcomings of an additive search strategy or when they were under a higher (vs. lower) cognitive load" (Adams et al., 2021, p. 258). Addition and subtraction are generally defined as de-contextualized mathematical operations using abstract symbols (Russell, 1903/1938). Nevertheless, understanding of both symbols and operations is informed by everyday activities, such as making or breaking objects (Lakoff and N{\´u}{\~n}ez, 2000; Fischer and Shaki, 2018). The universal attribution of "addition bias" or "subtraction neglect" to problem solving activities is perhaps a convenient shorthand but it overlooks influential framing effects beyond those already acknowledged in the report and the accompanying commentary (Meyvis and Yoon, 2021). Most importantly, while Adams et al.'s study addresses an important issue, their very method of verbally instructing participants, together with lack of control over several known biases, might render their findings less than conclusive. Below, we discuss our concerns that emerged from the identified biases, namely those regarding the instructions and the experimental materials. Moreover, we refer to research from mathematical cognition that provides new insights into Adams et al.'s findings.}, language = {en} } @article{KindermannDoblerNiedeggenetal.2022, author = {Kindermann, Liana and Dobler, Magnus and Niedeggen, Daniela and Chimbioputo Fabiano, Ezequiel and Linst{\"a}dter, Anja}, title = {Dataset on woody aboveground biomass, disturbance losses, and wood density from an African savanna ecosystem}, series = {Data in Brief}, volume = {42}, journal = {Data in Brief}, publisher = {Elsevier}, address = {Amsterdam, Niederlande}, issn = {2352-3409}, doi = {10.1016/j.dib.2022.108155}, pages = {1 -- 16}, year = {2022}, abstract = {This dataset comprises tree inventories and damage assessments performed in Namibia's semi-arid Zambezi Region. Data were sampled in savannas and savanna woodlands along steep gradients of elephant population densities to capture the effects of those (and other) disturbances on individual-level and stand-level aboveground woody biomass (AGB). The dataset contains raw data on dendrometric measures and processed data on specific wood density (SWD), woody aboveground biomass, and biomass losses through disturbance impacts. Allometric proxies (height, canopy diameters, and in adult trees also stem circumferences) were recorded for n = 6,179 tree and shrub individuals. Wood samples were taken for each encountered species to measure specific wood density. These measurements have been used to estimate woody aboveground biomass via established allometric models, advanced through our improved methodologies and workflows that accounted for tree and shrub architecture shaped by disturbance impacts. To this end, we performed a detailed damage assessment on each woody individual in the field. In addition to estimations of standing biomass, our new method also delivered data on biomass losses to different disturbance agents (elephants, fire, and others) on the level of plant individuals and stands. The data presented here have been used within a study published with Ecological Indicators (Kindermann et al., 2022) to evaluate the benefits of our improved methodology in comparison to a standard reference method of aboveground biomass estimations. Additionally, it has been employed in a study on carbon storage and sequestration in vegetation and soils (Sandhage-Hofmann et al., 2021). The raw data of dendrometric measurements can be subjected to other available allometric models for biomass estimation. The processed data can be used to analyze disturbance impacts on woody aboveground biomass, or for regional carbon storage estimates. The data on species-specific wood density can be used for application to other dendrometric datasets to (re-) estimate biomass through allometric models requiring wood density. It can further be used for plant functional trait analyses.}, language = {en} } @article{PerkinsRoseGrossartetal.2021, author = {Perkins, Anita and Rose, Andrew and Grossart, Hans-Peter and Rojas-Jimenez, Keilor Osvaldo and Barroso Prescott, Selva Kiri and Oakes, Joanne M.}, title = {Oxic and Anoxic Organic Polymer Degradation Potential of Endophytic Fungi From the Marine Macroalga, Ecklonia radiata}, series = {Frontiers in Microbiology}, volume = {12}, journal = {Frontiers in Microbiology}, publisher = {Frontiers in microbiology}, address = {Lausanne, Schweiz}, issn = {1664-302X}, doi = {10.3389/fmicb.2021.726138}, pages = {1 -- 13}, year = {2021}, abstract = {Cellulose and chitin are the most abundant polymeric, organic carbon source globally. Thus, microbes degrading these polymers significantly influence global carbon cycling and greenhouse gas production. Fungi are recognized as important for cellulose decomposition in terrestrial environments, but are far less studied in marine environments, where bacterial organic matter degradation pathways tend to receive more attention. In this study, we investigated the potential of fungi to degrade kelp detritus, which is a major source of cellulose in marine systems. Given that kelp detritus can be transported considerable distances in the marine environment, we were specifically interested in the capability of endophytic fungi, which are transported with detritus, to ultimately contribute to kelp detritus degradation. We isolated 10 species and two strains of endophytic fungi from the kelp Ecklonia radiata. We then used a dye decolorization assay to assess their ability to degrade organic polymers (lignin, cellulose, and hemicellulose) under both oxic and anoxic conditions and compared their degradation ability with common terrestrial fungi. Under oxic conditions, there was evidence that Ascomycota isolates produced cellulose-degrading extracellular enzymes (associated with manganese peroxidase and sulfur-containing lignin peroxidase), while Mucoromycota isolates appeared to produce both lignin and cellulose-degrading extracellular enzymes, and all Basidiomycota isolates produced lignin-degrading enzymes (associated with laccase and lignin peroxidase). Under anoxic conditions, only three kelp endophytes degraded cellulose. We concluded that kelp fungal endophytes can contribute to cellulose degradation in both oxic and anoxic environments. Thus, endophytic kelp fungi may play a significant role in marine carbon cycling via polymeric organic matter degradation.}, language = {en} } @article{DenzStellmacherUllrich2023, author = {Denz, Rebekka and Stellmacher, Martha and Ullrich, Rebecca}, title = {Einleitung}, series = {Genisa-Bl{\"a}tter IV}, journal = {Genisa-Bl{\"a}tter IV}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-539-2}, doi = {10.25932/publishup-58484}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-584843}, pages = {9 -- 13}, year = {2023}, language = {de} } @book{Denz2009, author = {Denz, Rebekka}, title = {Bundistinnen}, series = {Pri ha-Pardes}, journal = {Pri ha-Pardes}, number = {5}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-940793-58-4}, issn = {1863-7442}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-27889}, publisher = {Universit{\"a}t Potsdam}, pages = {169}, year = {2009}, abstract = {Pri ha-Pardes (Fr{\"u}chte des Obstgartens) ist eine Reihe der Vereinigung f{\"u}r J{\"u}dische Studien e.V., welche in Verbindung mit dem Zentrum f{\"u}r J{\"u}dische Studien der Universit{\"a}t Potsdam publiziert wird. Pri ha-Pardes m{\"o}chte kleineren wissenschaftlichen Studien, Forschungen am Rande der großen Disziplinen und exzellenten Masterarbeiten eine Publikationsplattform bieten. Im f{\"u}nften Band der Reihe Pri ha-Pardes skizziert Rebekka Denz die Geschichte von Frauen im Allgemeinen J{\"u}dischen Arbeiterbund („Bund") seit seiner Gr{\"u}ndung 1897 bis zum Jahr 1939. Durch das Prisma der gew{\"a}hlten Hauptquelle ─ die Frauenbiographien der „Doires Bundistn", einer jiddischsprachigen Biographiensammlung verfasst von Mitgliedern des „Bund" ─ werden das Mitwirken und die Bedeutung von Frauen in dieser sozialistischen, jiddischistischen Bewegung Ost(mittel)europas dargestellt. Zudem wird ein erster Versuch unternommen, diesen Teil der bundischen Parteigeschichtsschreibung hinsichtlich ihrer (Re-) Konstruktionsprinzipien zu lesen. Die Arbeit gliedert sich dabei analog zum bundischen Selbstverst{\"a}ndnis und der geographischen Verschiebung seines Hauptwirkungsfeldes in zwei Teile: Frauen im „Russischen Bund" (1897-1917) und Frauen im „Polnischen Bund" (1918-1939). Die Auswirkungen der unterschiedlichen historischen Kontexte auf lebensweltliche Aspekte, T{\"a}tigkeiten in Bewegung und Partei sowie Tendenzen der Lebensgestaltung der Bundistinnen werden anhand von drei Vergleichskapiteln aufgezeigt; weitere Einzelkapitel behandeln zeitspezifische Aspekte. Die Instabilit{\"a}t der Lebensverh{\"a}ltnisse f{\"u}r die Mitglieder im illegalen „Russischen Bund" bzw. die gr{\"o}ßere Stabilit{\"a}t in der Zeit des „Bund" in Polen als legale Partei bilden wichtige, bislang vernachl{\"a}ssigte Faktoren bei der Betrachtung der weiblichen Lebensmuster.}, language = {de} } @article{HauffeRathAgyapongetal.2022, author = {Hauffe, Robert and Rath, Michaela and Agyapong, Wilson and Jonas, Wenke and Vogel, Heike and Schulz, Tim Julius and Schwarz, Maria and Kipp, Anna Patricia and Bl{\"u}her, Matthias and Kleinridders, Andr{\´e}}, title = {Obesity Hinders the Protective Effect of Selenite Supplementation on Insulin Signaling}, series = {Antioxidants}, volume = {11}, journal = {Antioxidants}, edition = {5}, publisher = {MDPI}, address = {Basel, Schweiz}, issn = {2076-3921}, doi = {10.3390/antiox11050862}, pages = {1 -- 16}, year = {2022}, abstract = {The intake of high-fat diets (HFDs) containing large amounts of saturated long-chain fatty acids leads to obesity, oxidative stress, inflammation, and insulin resistance. The trace element selenium, as a crucial part of antioxidative selenoproteins, can protect against the development of diet-induced insulin resistance in white adipose tissue (WAT) by increasing glutathione peroxidase 3 (GPx3) and insulin receptor (IR) expression. Whether selenite (Se) can attenuate insulin resistance in established lipotoxic and obese conditions is unclear. We confirm that GPX3 mRNA expression in adipose tissue correlates with BMI in humans. Cultivating 3T3-L1 pre-adipocytes in palmitate-containing medium followed by Se treatment attenuates insulin resistance with enhanced GPx3 and IR expression and adipocyte differentiation. However, feeding obese mice a selenium-enriched high-fat diet (SRHFD) only resulted in a modest increase in overall selenoprotein gene expression in WAT in mice with unaltered body weight development, glucose tolerance, and insulin resistance. While Se supplementation improved adipocyte morphology, it did not alter WAT insulin sensitivity. However, mice fed a SRHFD exhibited increased insulin content in the pancreas. Overall, while selenite protects against palmitate-induced insulin resistance in vitro, obesity impedes the effect of selenite on insulin action and adipose tissue metabolism in vivo.}, language = {en} } @techreport{LessmannGrunerKalkuhletal.2024, type = {Working Paper}, author = {Lessmann, Kai and Gruner, Friedemann and Kalkuhl, Matthias and Edenhofer, Ottmar}, title = {Emissions Trading with Clean-up Certificates}, series = {CEPA Discussion Papers}, journal = {CEPA Discussion Papers}, number = {79}, issn = {2628-653X}, doi = {10.25932/publishup-64136}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-641368}, pages = {35}, year = {2024}, abstract = {We analyze how conventional emissions trading schemes (ETS) can be modified by introducing "clean-up certificates" to allow for a phase of net-negative emissions. Clean-up certificates bundle the permission to emit CO2 with the obligation for its removal. We show that demand for such certificates is determined by cost-saving technological progress, the discount rate and the length of the compliance period. Introducing extra clean-up certificates into an existing ETS reduces near-term carbon prices and mitigation efforts. In contrast, substituting ETS allowances with clean-up certificates reduces cumulative emissions without depressing carbon prices or mitigation in the near term. We calibrate our model to the EU ETS and identify reforms where simultaneously (i) ambition levels rise, (ii) climate damages fall, (iii) revenues from carbon prices rise and (iv) carbon prices and aggregate mitigation cost fall. For reducing climate damages, roughly half of the issued clean-up certificates should replace conventional ETS allowances. In the context of the EU ETS, a European Carbon Central Bank could manage the implementation of cleanup certificates and could serve as an enforcement mechanism.}, language = {en} } @book{SchmidtUlrichBuechneretal.2024, author = {Schmidt, Thorsten Ingo and Ulrich, Peter and B{\"u}chner, Christiane and Franzke, Jochen and Jann, Werner and Bauer, Hartmut and Wagner, Dieter and Br{\"u}ning, Christoph and Bickenbach, Christian and Kuhlmann, Sabine and Peters, Niklas and Reichard, Christoph and Tessmann, Jens and Maaß, Christian and Kern, Kristine and Kochsk{\"a}mper, Elisa and Gailing, Ludger and Krzymuski, Marcin}, title = {Kommunalwissenschaften an der Universit{\"a}t Potsdam}, series = {KWI-Schriften}, journal = {KWI-Schriften}, number = {15}, editor = {Schmidt, Thorsten Ingo and Bickenbach, Christian and Gronewold, Ulfert and Kuhlmann, Sabine and Ulrich, Peter}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-581-1}, issn = {1867-951X}, doi = {10.25932/publishup-63618}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-636180}, publisher = {Universit{\"a}t Potsdam}, pages = {124}, year = {2024}, abstract = {Zum dreißigj{\"a}hrigen Bestehen des Kommunalwissenschaftlichen Instituts an der Universit{\"a}t Potsdam vereint dieser Jubil{\"a}umsband kurze Aufs{\"a}tze von ehemaligen und aktuellen Vorstandsmitgliedern, von Ehrenmitgliedern des Vorstands, langj{\"a}hrigen wissenschaftlichen Mitarbeitern des Instituts und aktuellen wissenschaftlichen Kooperationspartnern. Die insgesamt zw{\"o}lf Beitr{\"a}ge befassen sich mit den Kommunalwissenschaften und der Geschichte des Kommunalwissenschaftlichen Instituts, mit aktuellen kommunalwissenschaftlichen Fragestellungen und wissenschaftlichen Kooperationen des KWI. Der vom KWI-Vorstand herausgegebene Band soll einen breiten Blick auf 30 Jahre Kommunalwissenschaften in Brandenburg und an der Universit{\"a}t Potsdam werfen und einen Ausblick auf zuk{\"u}nftige kommunalwissenschaftliche Forschung geben.}, language = {de} } @article{Maass2024, author = {Maaß, Christian}, title = {Brandenburg, (k)ein Land der Reformen?}, series = {Kommunalwissenschaften an der Universit{\"a}t Potsdam (KWI-Schriften ; 15)}, journal = {Kommunalwissenschaften an der Universit{\"a}t Potsdam (KWI-Schriften ; 15)}, number = {15}, editor = {Schmidt, Thorsten Ingo and Bickenbach, Christian and Gronewold, Ulfert and Kuhlmann, Sabine and Ulrich, Peter}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-581-1}, issn = {1867-951X}, doi = {10.25932/publishup-64787}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-647878}, pages = {87 -- 98}, year = {2024}, language = {de} } @article{KernKochskaemper2024, author = {Kern, Kristine and Kochsk{\"a}mper, Elisa}, title = {Wege zur urbanen Transformation}, series = {Kommunalwissenschaften an der Universit{\"a}t Potsdam (KWI-Schriften ; 15)}, journal = {Kommunalwissenschaften an der Universit{\"a}t Potsdam (KWI-Schriften ; 15)}, number = {15}, editor = {Schmidt, Thorsten Ingo and Bickenbach, Christian and Gronewold, Ulfert and Kuhlmann, Sabine and Ulrich, Peter}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-581-1}, issn = {1867-951X}, doi = {10.25932/publishup-64788}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-647882}, pages = {101 -- 109}, year = {2024}, language = {de} } @article{Gailing2024, author = {Gailing, Ludger}, title = {Regionalplanung - und die Kommunalwissenschaften}, series = {Kommunalwissenschaften an der Universit{\"a}t Potsdam (KWI-Schriften ; 15)}, journal = {Kommunalwissenschaften an der Universit{\"a}t Potsdam (KWI-Schriften ; 15)}, number = {15}, editor = {Schmidt, Thorsten Ingo and Bickenbach, Christian and Gronewold, Ulfert and Kuhlmann, Sabine and Ulrich, Peter}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-581-1}, issn = {1867-951X}, doi = {10.25932/publishup-64789}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-647899}, pages = {111 -- 120}, year = {2024}, language = {de} } @article{Tessmann2024, author = {Tessmann, Jens}, title = {Organisationsvarianten kommunaler Selbstverwaltung in Deutschland}, series = {Kommunalwissenschaften an der Universit{\"a}t Potsdam (KWI-Schriften ; 15)}, journal = {Kommunalwissenschaften an der Universit{\"a}t Potsdam (KWI-Schriften ; 15)}, number = {15}, editor = {Schmidt, Thorsten Ingo and Bickenbach, Christian and Gronewold, Ulfert and Kuhlmann, Sabine and Ulrich, Peter}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-581-1}, issn = {1867-951X}, doi = {10.25932/publishup-64786}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-647869}, pages = {79 -- 85}, year = {2024}, language = {de} } @article{Krzymuski2024, author = {Krzymuski, Marcin}, title = {Ph{\"a}nomen des Kollisionsrechts im Verwaltungsrecht?}, series = {Kommunalwissenschaften an der Universit{\"a}t Potsdam (KWI-Schriften ; 15)}, journal = {Kommunalwissenschaften an der Universit{\"a}t Potsdam (KWI-Schriften ; 15)}, number = {15}, editor = {Schmidt, Thorsten Ingo and Bickenbach, Christian and Gronewold, Ulfert and Kuhlmann, Sabine and Ulrich, Peter}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-581-1}, issn = {1867-951X}, doi = {10.25932/publishup-64791}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-647912}, pages = {121 -- 124}, year = {2024}, language = {de} } @misc{WernerCiceroneKliegletal.1984, author = {Werner, John S. and Cicerone, Carola M. and Kliegl, Reinhold and DellaRosa, Denise}, title = {Spectral efficiency of blackness induction}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-16897}, year = {1984}, abstract = {The spectral efficiency of blackness induction was measured in three normal trichromatic observers and in one deuteranomalous observer. The psychophysical task was to adjust the radiance of a monochromatic 60-120′ annulus until a 45′ central broadband field just turned black and its contour became indiscriminable from a dark surrounding gap that separated it from the annulus. The reciprocal of the radiance required to induce blackness with annulus wavelengths between 420 and 680 nm was used to define a spectral-efficiency function for the blackness component of the achromatic process. For each observer, the shape of this blackness-sensitivity function agreed with the spectral-efficiency function based on heterochromatic flicker photometry when measured with the same 60-120′ annulus. Both of these functions matched the Commission Internationale de l'Eclairage Vλ function except at short wavelengths. Ancillary measurements showed that the latter difference in sensitivity can be ascribed to nonuniformities of preretinal absorption, since the annular field excluded the central 60′ of the fovea. Thus our evidence indicates that, at least to a good first approximation, induced blackness is inversely related to the spectral-luminosity function. These findings are consistent with a model that separates the achromatic and the chromatic pathways.}, language = {en} } @phdthesis{Videla2014, author = {Videla, Santiago}, title = {Reasoning on the response of logical signaling networks with answer set programming}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-71890}, school = {Universit{\"a}t Potsdam}, year = {2014}, abstract = {Deciphering the functioning of biological networks is one of the central tasks in systems biology. In particular, signal transduction networks are crucial for the understanding of the cellular response to external and internal perturbations. Importantly, in order to cope with the complexity of these networks, mathematical and computational modeling is required. We propose a computational modeling framework in order to achieve more robust discoveries in the context of logical signaling networks. More precisely, we focus on modeling the response of logical signaling networks by means of automated reasoning using Answer Set Programming (ASP). ASP provides a declarative language for modeling various knowledge representation and reasoning problems. Moreover, available ASP solvers provide several reasoning modes for assessing the multitude of answer sets. Therefore, leveraging its rich modeling language and its highly efficient solving capacities, we use ASP to address three challenging problems in the context of logical signaling networks: learning of (Boolean) logical networks, experimental design, and identification of intervention strategies. Overall, the contribution of this thesis is three-fold. Firstly, we introduce a mathematical framework for characterizing and reasoning on the response of logical signaling networks. Secondly, we contribute to a growing list of successful applications of ASP in systems biology. Thirdly, we present a software providing a complete pipeline for automated reasoning on the response of logical signaling networks.}, language = {en} } @article{HeimannJelinek2024, author = {Heimann-Jelinek, Felicitas}, title = {What was "Jewish" about the Old Jewish Museum of Vienna?}, series = {PaRDeS}, journal = {PaRDeS}, number = {29}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-574-3}, issn = {1614-6492}, doi = {10.25932/publishup-65028}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-650283}, pages = {125 -- 134}, year = {2024}, abstract = {The Jewish museums established in the fin-de-si{\`e}cle Habsburg Empire postulated the unity of "the Jewish people," with custodians constructing an "us" (Jews) in distinction to the "other" (non-Jews). In the difference-oriented frenzy of the time, Jewish identity was predominantly presented as Central European, enlightened, not overly religious, and middle-class. Then, when the Viennese Jewish Museum opened its doors in 1895, the painters Isidor Kaufmann and David Kohn created an installation called "Die Gute Stube" (The Parlor). This exhibit housed books, furniture, as well as decorative and ritual objects of the kind that were thought to be found in typical Eastern European Jewish households. However, as this article argues, this attempted visualization of the essence of Judaism and the range of Jewish life worlds promoted a paradigmatic stereotype with which Jewish museums would have to struggle for decades to come.}, language = {en} } @phdthesis{Brill2022, author = {Brill, Fabio Alexander}, title = {Applications of machine learning and open geospatial data in flood risk modelling}, doi = {10.25932/publishup-55594}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-555943}, school = {Universit{\"a}t Potsdam}, pages = {xix, 124}, year = {2022}, abstract = {Der technologische Fortschritt erlaubt es, zunehmend komplexe Vorhersagemodelle auf Basis immer gr{\"o}ßerer Datens{\"a}tze zu produzieren. F{\"u}r das Risikomanagement von Naturgefahren sind eine Vielzahl von Modellen als Entscheidungsgrundlage notwendig, z.B. in der Auswertung von Beobachtungsdaten, f{\"u}r die Vorhersage von Gefahrenszenarien, oder zur statistischen Absch{\"a}tzung der zu erwartenden Sch{\"a}den. Es stellt sich also die Frage, inwiefern moderne Modellierungsans{\"a}tze wie das maschinelle Lernen oder Data-Mining in diesem Themenbereich sinnvoll eingesetzt werden k{\"o}nnen. Zus{\"a}tzlich ist im Hinblick auf die Datenverf{\"u}gbarkeit und -zug{\"a}nglichkeit ein Trend zur {\"O}ffnung (open data) zu beobachten. Thema dieser Arbeit ist daher, die M{\"o}glichkeiten und Grenzen des maschinellen Lernens und frei verf{\"u}gbarer Geodaten auf dem Gebiet der Hochwasserrisikomodellierung im weiteren Sinne zu untersuchen. Da dieses {\"u}bergeordnete Thema sehr breit ist, werden einzelne relevante Aspekte herausgearbeitet und detailliert betrachtet. Eine prominente Datenquelle im Bereich Hochwasser ist die satellitenbasierte Kartierung von {\"U}berflutungsfl{\"a}chen, die z.B. {\"u}ber den Copernicus Service der Europ{\"a}ischen Union frei zur Verf{\"u}gung gestellt werden. Große Hoffnungen werden in der wissenschaftlichen Literatur in diese Produkte gesetzt, sowohl f{\"u}r die akute Unterst{\"u}tzung der Einsatzkr{\"a}fte im Katastrophenfall, als auch in der Modellierung mittels hydrodynamischer Modelle oder zur Schadensabsch{\"a}tzung. Daher wurde ein Fokus in dieser Arbeit auf die Untersuchung dieser Flutmasken gelegt. Aus der Beobachtung, dass die Qualit{\"a}t dieser Produkte in bewaldeten und urbanen Gebieten unzureichend ist, wurde ein Verfahren zur nachtr{\"a}glichenVerbesserung mittels maschinellem Lernen entwickelt. Das Verfahren basiert auf einem Klassifikationsalgorithmus der nur Trainingsdaten von einer vorherzusagenden Klasse ben{\"o}tigt, im konkreten Fall also Daten von {\"U}berflutungsfl{\"a}chen, nicht jedoch von der negativen Klasse (trockene Gebiete). Die Anwendung f{\"u}r Hurricane Harvey in Houston zeigt großes Potenzial der Methode, abh{\"a}ngig von der Qualit{\"a}t der urspr{\"u}nglichen Flutmaske. Anschließend wird anhand einer prozessbasierten Modellkette untersucht, welchen Einfluss implementierte physikalische Prozessdetails auf das vorhergesagte statistische Risiko haben. Es wird anschaulich gezeigt, was eine Risikostudie basierend auf etablierten Modellen leisten kann. Solche Modellketten sind allerdings bereits f{\"u}r Flusshochwasser sehr komplex, und f{\"u}r zusammengesetzte oder kaskadierende Ereignisse mit Starkregen, Sturzfluten, und weiteren Prozessen, kaum vorhanden. Im vierten Kapitel dieser Arbeit wird daher getestet, ob maschinelles Lernen auf Basis von vollst{\"a}ndigen Schadensdaten einen direkteren Weg zur Schadensmodellierung erm{\"o}glicht, der die explizite Konzeption einer solchen Modellkette umgeht. Dazu wird ein staatlich erhobener Datensatz der gesch{\"a}digten Geb{\"a}ude w{\"a}hrend des schweren El Ni{\~n}o Ereignisses 2017 in Peru verwendet. In diesem Kontext werden auch die M{\"o}glichkeiten des Data-Mining zur Extraktion von Prozessverst{\"a}ndnis ausgelotet. Es kann gezeigt werden, dass diverse frei verf{\"u}gbare Geodaten n{\"u}tzliche Informationen f{\"u}r die Gefahren- und Schadensmodellierung von komplexen Flutereignissen liefern, z.B. satellitenbasierte Regenmessungen, topographische und hydrographische Information, kartierte Siedlungsfl{\"a}chen, sowie Indikatoren aus Spektraldaten. Zudem zeigen sich Erkenntnisse zu den Sch{\"a}digungsprozessen, die im Wesentlichen mit den vorherigen Erwartungen in Einklang stehen. Die maximale Regenintensit{\"a}t wirkt beispielsweise in St{\"a}dten und steilen Schluchten st{\"a}rker sch{\"a}digend, w{\"a}hrend die Niederschlagssumme in tiefliegenden Flussgebieten und bewaldeten Regionen als aussagekr{\"a}ftiger befunden wurde. L{\"a}ndliche Gebiete in Peru weisen in der pr{\"a}sentierten Studie eine h{\"o}here Vulnerabilit{\"a}t als die Stadtgebiete auf. Jedoch werden auch die grunds{\"a}tzlichen Grenzen der Methodik und die Abh{\"a}ngigkeit von spezifischen Datens{\"a}tzen and Algorithmen offenkundig. In der {\"u}bergreifenden Diskussion werden schließlich die verschiedenen Methoden - prozessbasierte Modellierung, pr{\"a}diktives maschinelles Lernen, und Data-Mining - mit Blick auf die Gesamtfragestellungen evaluiert. Im Bereich der Gefahrenbeobachtung scheint eine Fokussierung auf neue Algorithmen sinnvoll. Im Bereich der Gefahrenmodellierung, insbesondere f{\"u}r Flusshochwasser, wird eher die Verbesserung von physikalischen Modellen, oder die Integration von prozessbasierten und statistischen Verfahren angeraten. In der Schadensmodellierung fehlen nach wie vor die großen repr{\"a}sentativen Datens{\"a}tze, die f{\"u}r eine breite Anwendung von maschinellem Lernen Voraussetzung ist. Daher ist die Verbesserung der Datengrundlage im Bereich der Sch{\"a}den derzeit als wichtiger einzustufen als die Auswahl der Algorithmen.}, language = {en} } @phdthesis{Schifferle2024, author = {Schifferle, Lukas}, title = {Optical properties of (Mg,Fe)O at high pressure}, doi = {10.25932/publishup-62216}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-622166}, school = {Universit{\"a}t Potsdam}, pages = {XIV, 90}, year = {2024}, abstract = {Large parts of the Earth's interior are inaccessible to direct observation, yet global geodynamic processes are governed by the physical material properties under extreme pressure and temperature conditions. It is therefore essential to investigate the deep Earth's physical properties through in-situ laboratory experiments. With this goal in mind, the optical properties of mantle minerals at high pressure offer a unique way to determine a variety of physical properties, in a straight-forward, reproducible, and time-effective manner, thus providing valuable insights into the physical processes of the deep Earth. This thesis focusses on the system Mg-Fe-O, specifically on the optical properties of periclase (MgO) and its iron-bearing variant ferropericlase ((Mg,Fe)O), forming a major planetary building block. The primary objective is to establish links between physical material properties and optical properties. In particular the spin transition in ferropericlase, the second-most abundant phase of the lower mantle, is known to change the physical material properties. Although the spin transition region likely extends down to the core-mantle boundary, the ef-fects of the mixed-spin state, where both high- and low-spin state are present, remains poorly constrained. In the studies presented herein, we show how optical properties are linked to physical properties such as electrical conductivity, radiative thermal conductivity and viscosity. We also show how the optical properties reveal changes in the chemical bonding. Furthermore, we unveil how the chemical bonding, the optical and other physical properties are affected by the iron spin transition. We find opposing trends in the pres-sure dependence of the refractive index of MgO and (Mg,Fe)O. From 1 atm to ~140 GPa, the refractive index of MgO decreases by ~2.4\% from 1.737 to 1.696 (±0.017). In contrast, the refractive index of (Mg0.87Fe0.13)O (Fp13) and (Mg0.76Fe0.24)O (Fp24) ferropericlase increases with pressure, likely because Fe Fe interactions between adjacent iron sites hinder a strong decrease of polarizability, as it is observed with increasing density in the case of pure MgO. An analysis of the index dispersion in MgO (decreasing by ~23\% from 1 atm to ~103 GPa) reflects a widening of the band gap from ~7.4 eV at 1 atm to ~8.5 (±0.6) eV at ~103 GPa. The index dispersion (between 550 and 870 nm) of Fp13 reveals a decrease by a factor of ~3 over the spin transition range (~44-100 GPa). We show that the electrical band gap of ferropericlase significantly widens up to ~4.7 eV in the mixed spin region, equivalent to an increase by a factor of ~1.7. We propose that this is due to a lower electron mobility between adjacent Fe2+ sites of opposite spin, explaining the previously observed low electrical conductivity in the mixed spin region. From the study of absorbance spectra in Fp13, we show an increasing covalency of the Fe-O bond with pressure for high-spin ferropericlase, whereas in the low-spin state a trend to a more ionic nature of the Fe-O bond is observed, indicating a bond weakening effect of the spin transition. We found that the spin transition is ultimately caused by both an increase of the ligand field-splitting energy and a decreasing spin-pairing energy of high-spin Fe2+.}, language = {en} } @article{KuehneFauthAyBrysonetal.2021, author = {K{\"u}hne, Franziska and Fauth, Henriette and Ay-Bryson, Destina Sevde and Visser, Leonie N.C. and Weck, Florian}, title = {Communicating the diagnosis of cancer or depression}, series = {Cancer medicine}, volume = {10}, journal = {Cancer medicine}, number = {24}, publisher = {Wiley}, address = {Hoboken, New Jersey, USA}, issn = {2045-7634}, doi = {10.1002/cam4.4396}, pages = {9012 -- 9021}, year = {2021}, abstract = {Background Communicating a diagnosis is highly important, yet complex, especially in the context of cancer and mental disorders. The aim was to explore the communication style of an oncologist vs. psychotherapist in an online study. Methods Patients (N = 136: 65 cancer, 71 depression) were randomly assigned to watch a standardized video vignette with one of two communication styles (empathic vs. unempathic). Outcome measures of affectivity, information recall, communication skills, empathy and trust were applied. Results Regardless of diagnosis, empathic communication was associated with the perception of a significantly more empathic (p < 0.001, η2partial = 0.08) and trustworthy practitioner (p = 0.014, η2partial = 0.04) with better communication skills (p = 0.013, η2partial = 0.05). Cancer patients reported a larger decrease in positive affect (p < 0.001, η2partial = 0.15) and a larger increase in negative affect (p < 0.001, η2partial = 0.14) from pre- to post-video than depressive patients. Highly relevant information was recalled better in both groups (p < 0.001, d = 0.61-1.06). Conclusions The results highlight the importance of empathy while communicating both a diagnosis of cancer and a mental disorder. Further research should focus on the communication of a mental disorder in association with cancer.}, language = {en} } @phdthesis{Martin2024, author = {Martin, Johannes}, title = {Synthesis of protein-polymer conjugates and block copolymers via sortase-mediated ligation}, doi = {10.25932/publishup-64566}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-645669}, school = {Universit{\"a}t Potsdam}, pages = {XVII, 150}, year = {2024}, abstract = {In den vergangenen Jahrzehnten haben therapeutische Proteine in der pharmazeutischen Industrie mehr und mehr an Bedeutung gewonnen. Werden Proteine nichtmenschlichen Ursprungs verwendet, kann es jedoch zu einer Immunreaktion kommen, sodass das Protein sehr schnell aus dem K{\"o}rper ausgeschieden oder abgebaut wird. Um die Zirkulationszeit im Blut signifikant zu verl{\"a}ngern, werden die Proteine mit synthetischen Polymeren modifiziert (Protein-Polymer-Konjugate). Die Proteine aller heute auf dem Markt erh{\"a}ltlichen Medikamente dieser Art tragen eine oder mehrere Polymerketten aus Poly(ethylenglycol) (PEG). Ein Nachteil der PEGylierung ist, dass viele Patienten bei regelm{\"a}ßiger Einnahme dieser Medikamente Antik{\"o}rper gegen PEG entwickeln, die den effizienzsteigernden Effekt der PEGylierung wieder aufheben. Ein weiterer Nachteil der PEGylierung ist die oftmals deutlich verringerte Aktivit{\"a}t der Konjugate im Vergleich zum nativen Protein. Der Grund daf{\"u}r ist die Herstellungsmethode der Konjugate, bei der meist die prim{\"a}ren Amine der Lysin-Seitenketten und der N-Terminus des Proteins genutzt werden. Da die meisten Proteine mehrere gut zug{\"a}ngliche Lysine aufweisen, werden oft unterschiedliche und teilweise mehrere Lysine mit PEG funktionalisiert, was zu einer Mischung an Regioisomeren f{\"u}hrt. Je nach Position der PEG-Kette kann das aktive Zentrum abgeschirmt oder die 3D-Struktur des Proteins ver{\"a}ndert werden, was zu einem teilweise drastischen Aktivit{\"a}tsabfall f{\"u}hrt. In dieser Arbeit wurde eine neuartige Methode zur Ligation von Makromolek{\"u}len untersucht. Die Verwendung eines Enzyms als Katalysator zur Verbindung zweier Makromolek{\"u}le ist bisher wenig untersucht und ineffizient. Als Enzym wurde Sortase A ausgew{\"a}hlt, eine gut untersuchte Ligase aus der Familie der Transpeptidasen, welche die Ligation zweier Peptide katalysieren kann. Ein Nachteil dieser Sortase-vermittelten Ligation ist, dass es sich um eine Gleichgewichtsreaktion handelt, wodurch hohe Ausbeuten schwierig zu erreichen sind. Im Rahmen dieser Dissertation wurden zwei zuvor entwickelte Methoden zur Verschiebung des Gleichgewichts ohne Einsatz eines großen {\"U}berschusses von einem Edukt f{\"u}r Makromolek{\"u}le {\"u}berpr{\"u}ft. Zur Durchf{\"u}hrung der Sortase-vermittelten Ligation werden zwei komplement{\"a}re Peptidsequenzen verwendet, die Erkennungssequenz und das Nukleophil. Um eine systematische Untersuchung durchf{\"u}hren zu k{\"o}nnen, wurden alle n{\"o}tigen Bausteine (Protein-Erkennungssequenz zur Reaktion mit Nukleophil-Polymer und Polymer-Erkennungssequenz mit Nukleophil-Protein) hergestellt. Als Polymerisationstechnik wurde die radikalische Polymerisation mit reversibler Deaktivierung (im Detail, Atom Transfer Radical Polymerization, ATRP und Reversible Addition-Fragmentation Chain Transfer, RAFT polymerization) gew{\"a}hlt, um eine enge Molmassenverteilung zu erreichen. Die Herstellung der Bausteine begann mit der Synthese der Peptide via automatisierter Festphasen-Peptidsynthese, um eine einfache {\"A}nderung der Peptidsequenz zu gew{\"a}hrleisten und um eine Modifizierung der Polymerkette nach der Polymerisation zu umgehen. Um die ben{\"o}tigte unterschiedliche Funktionalit{\"a}t der zwei Peptidsequenzen (freier C-Terminus bei der Erkennungssequenz bzw. freier N-Terminus bei dem Nukleophil) zu erreichen, wurden verschiedene Linker zwischen Harz und Peptid verwendet. Danach wurde der Ketten{\"u}bertr{\"a}ger (chain transfer agent, CTA) zur Kontrolle der Polymerisation mit dem auf dem Harz befindlichen Peptid gekoppelt. Die f{\"u}r die anschließende Polymerisation verwendeten Monomere basierten auf Acrylamiden und Acrylaten und wurden anhand ihrer Eignung als Alternativen zu PEG ausgew{\"a}hlt. Es wurde eine k{\"u}rzlich entwickelte Technik basierend auf der RAFT-Polymerisation (xanthate-supported photo-iniferter RAFT, XPI-RAFT) verwendet um eine Reihe an Peptid-Polymeren mit unterschiedlichen Molekulargewichten und engen Molekulargewichtsverteilungen herzustellen. Nach Entfernung der Schutzgruppen der Peptid-Seitenketten wurden die Peptid-Polymere zun{\"a}chst genutzt, um mittels Sortase-vermittelter Ligation zwei Polymerketten zu einem Blockcopolymer zu verbinden. Unter Verwendung von Ni2+-Ionen in Kombination mit einer Verl{\"a}ngerung der Erkennungssequenz um ein Histidin zur Unterdr{\"u}ckung der R{\"u}ckreaktion konnte ein maximaler Umsatz von 70 \% erreicht werden. Dabei zeigte sich ein oberes Limit von durchschnittlich 100 Wiederholungseinheiten; die Ligation von l{\"a}ngeren Polymeren war nicht erfolgreich. Danach wurden ein Modellprotein und ein Nanobody mit vielversprechenden medizinischen Eigenschaften mit den f{\"u}r die enzymkatalysierte Ligation ben{\"o}tigten Peptidsequenzen f{\"u}r die Kopplung mit den zuvor hergestellten Peptid-Polymeren verwendet. Dabei konnte bei Verwendung des Modellproteins keine Bildung von Protein-Polymer-Konjugaten beobachtet werden. Der Nanobody konnte dagegen C-terminal mit einem Polymer funktionalisiert werden. Dabei wurde eine {\"a}hnliche Limitierung in der Polymer-Kettenl{\"a}nge beobachtet wie zuvor. Die auf Ni-Ionen basierte Strategie zur Gleichgewichtsverschiebung hatte hier keinen ausschlaggebenden Effekt, w{\"a}hrend die Verwendung von einem {\"U}berschuss an Polymer zur vollst{\"a}ndigen Umsetzung des Edukt-Nanobody f{\"u}hrte. Die erhaltenen Daten aus diesem Projekt bilden eine gute Basis f{\"u}r weitere Forschung in dem vielversprechenden Feld der enzymkatalysierten Herstellung von Protein-Polymer-Konjugaten und Blockcopolymeren. Langfristig k{\"o}nnte diese Herangehensweise eine vielseitig einsetzbare Herstellungsmethode von ortsspezifischen therapeutischen Protein-Polymer Konjugaten darstellen, welche sowohl eine hohe Aktivit{\"a}t als auch eine lange Zirkulationszeit im Blut aufweisen.}, language = {en} } @article{GiraudierVenturaBortWendtetal.2022, author = {Giraudier, Manon and Ventura-Bort, Carlos and Wendt, Julia and Lischke, Alexander and Weymar, Mathias}, title = {Memory advantage for untrustworthy faces: Replication across lab- and web-based studies}, series = {PLoS ONE}, volume = {17}, journal = {PLoS ONE}, edition = {2}, publisher = {PLoS ONE}, address = {San Francisco, California, US}, issn = {1932-6203}, doi = {10.1371/journal.pone.0264034}, pages = {1 -- 11}, year = {2022}, abstract = {The Covid-19 pandemic imposed new constraints on empirical research and forced researchers to transfer from traditional laboratory research to the online environment. This study tested the validity of a web-based episodic memory paradigm by comparing participants' memory performance for trustworthy and untrustworthy facial stimuli in a supervised laboratory setting and an unsupervised web setting. Consistent with previous results, we observed enhanced episodic memory for untrustworthy compared to trustworthy faces. Most importantly, this memory bias was comparable in the online and the laboratory experiment, suggesting that web-based procedures are a promising tool for memory research.}, language = {en} } @article{GiraudierVenturaBortBurgeretal.2022, author = {Giraudier, Manon and Ventura-Bort, Carlos and Burger, Andreas M. and Claes, Nathalie and D'Agostini, Martina and Fischer, Rico and Franssen, Mathijs and Kaess, Michael and Koenig, Julian and Liepelt, Roman and Nieuwenhuis, Sander and Sommer, Aldo and Usichenko, Taras and Van Diest, Ilse and von Leupoldt, Andreas and Warren, Christopher Michael and Weymar, Mathias}, title = {Evidence for a modulating effect of transcutaneous auricular vagus nerve stimulation (taVNS) on salivary alpha-amylase as indirect noradrenergic marker: A pooled mega-analysis}, series = {Brain Stimulation}, volume = {15}, journal = {Brain Stimulation}, edition = {6}, publisher = {Elsevier}, address = {New York, NY, USA}, issn = {1876-4754}, doi = {10.1016/j.brs.2022.09.009}, pages = {1378 -- 1388}, year = {2022}, abstract = {Background Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) has received tremendous attention as a potential neuromodulator of cognitive and affective functions, which likely exerts its effects via activation of the locus coeruleus-noradrenaline (LC-NA) system. Reliable effects of taVNS on markers of LC-NA system activity, however, have not been demonstrated yet. Methods The aim of the present study was to overcome previous limitations by pooling raw data from a large sample of ten taVNS studies (371 healthy participants) that collected salivary alpha-amylase (sAA) as a potential marker of central NA release. Results While a meta-analytic approach using summary statistics did not yield any significant effects, linear mixed model analyses showed that afferent stimulation of the vagus nerve via taVNS increased sAA levels compared to sham stimulation (b = 0.16, SE = 0.05, p = 0.001). When considering potential confounders of sAA, we further replicated previous findings on the diurnal trajectory of sAA activity. Conclusion(s) Vagal activation via taVNS increases sAA release compared to sham stimulation, which likely substantiates the assumption that taVNS triggers NA release. Moreover, our results highlight the benefits of data pooling and data sharing in order to allow stronger conclusions in research.}, language = {en} } @inproceedings{Sommer2006, author = {Sommer, Michael}, title = {Nicht-invasive Methoden in der Bodenlandschaftsforschung}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-7117}, year = {2006}, abstract = {Der Referent ist Leiter des Institutes f{\"u}r Bodenlandschaftsforschung am Leibniz-Zentrum f{\"u}r Agrarlandschaftsforschung (ZALF) e. V. in M{\"u}ncheberg.}, language = {de} } @misc{OPUS4-64958, title = {Erkl{\"a}rung Potsdamer B{\"u}rgerinnen und B{\"u}rger zur Robotik in der Altenpflege}, editor = {Bubeck, Marc and Haltaufderheide, Joschka and Sakowsky, Ruben Andreas and Ranisch, Robert}, doi = {10.25932/publishup-64958}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-649589}, pages = {53}, year = {2024}, abstract = {Die bedarfsgerechte Versorgung im Alter zuk{\"u}nftig sicherzustellen, geh{\"o}rt zu den entscheidenden Aufgaben unserer Zeit. Der in Deutschland bestehende Fachkr{\"a}ftemangel sowie der demografische Wandel belasten das Pflegesystem in mehrfacher Hinsicht: In einer alternden Gesellschaft sind immer mehr Menschen auf eine anhaltende Unterst{\"u}tzung angewiesen. Niedrige Geburtenraten und damit verbunden ein sinkender Bev{\"o}lkerungs-anteil von Menschen im erwerbsf{\"a}higen Alter bringen einen bereits heute sp{\"u}rbaren Mangel an beruflich Pflegenden mit sich. Um eine menschenw{\"u}rdige Pflege anhaltend zu gew{\"a}hrleisten, m{\"u}ssen vorhandene Ressourcen gezielter eingesetzt und zus{\"a}tzliche Reserven freigelegt werden. Viele Hoffnungen liegen hier auf technologischen Innovationen. Die Digitalisierung soll das Gesundheitswesen effizienter gestalten und beispielsweise durch K{\"u}nstliche Intelligenz zeitraubende Prozesse vereinfachen oder sogar automatisieren. Im Kontext der Pflege wird der Einsatz von robotischen Assistenzsystemen diskutiert. Aus diesem Grund wurde die die Potsdamer B{\"u}rger:innenkonferenz „Robotik in der Altenpflege?" initiiert. Um die Zukunft der Pflege gemeinsam zu gestalten, wurden 3.500 Potsdamer B{\"u}rgerinnen und B{\"u}rger kontaktiert und schließlich f{\"u}nfundzwanzig Teilnehmende ausgew{\"a}hlt. Im Fr{\"u}hjahr 2024 kamen sie zusammen, um den verantwortlichen Einsatz von Robotik in der Pflege zu diskutieren. Die hier vorliegende Erkl{\"a}rung ist das Ergebnis der B{\"u}rger:innenkonferenz. Sie enth{\"a}lt die zentralen Positionen der Teilnehmenden. Die B{\"u}rger:innenkonferenz ist Teil des Projekts E-cARE („Ethics Guidelines for Socially Assistive Robots in Elderly Care: An Empirical-Participatory Approach"), welches die Juniorprofessur f{\"u}r Medizinische Ethik mit Schwerpunkt auf Digitalisierung der Fakult{\"a}t f{\"u}r Gesundheitswissenschaften Brandenburg, Universit{\"a}t Potsdam, durchgef{\"u}hrt hat.}, language = {de} }