@techreport{MeyerKleinknechtRichter2022, author = {Meyer, Andr{\´e} and Kleinknecht, Marc and Richter, Dirk}, title = {Abschlussbericht im BMBF-Projekt "Verbundprojekt E-LANE: E-Learning in der Lehrerfortbildung: Angebote, Nutzung und Ertr{\"a}ge" (F{\"o}rderkennzeichen: 01JD1825A-B)}, doi = {10.25932/publishup-56742}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-567428}, pages = {16}, year = {2022}, abstract = {Der vorliegende Abschlussbericht pr{\"a}sentiert die Ergebnisse des BMBF-gef{\"o}rderten Verbundprojektes "E-LANE: E-Learning in der Lehrerfortbildung: Angebote, Nutzung und Ertr{\"a}ge", das gemeinsam durch die Universit{\"a}t Potsdam (Prof. Dr. Dirk Richter) und der Leuphana Universit{\"a}t L{\"u}neburg (Prof. Dr. Marc Kleinknecht) durchgef{\"u}hrt wurde. Ziel des Projektes war die Untersuchung des Angebotes von digitalen bzw. digital-gest{\"u}tzten Fortbildungen f{\"u}r Lehrkr{\"a}fte in den Bundesl{\"a}ndern Berlin, Brandenburg und Schleswig-Holstein. Im Rahmen von vier Teilstudien wurden Datenbankanalysen der Fortbildungsangebote in den jeweiligen L{\"a}ndern sowie schriftliche Befragungen mit Fortbildner*innen sowie Teilnehmer*innen von Online-Fortbildungen durchgef{\"u}hrt. Dar{\"u}ber hinaus wurde eine Online-Fortbildung f{\"u}r Lehrkr{\"a}fte zum Thema Feedback eigens konzipiert und durchgef{\"u}hrt.}, language = {de} } @phdthesis{Kegelmann2019, author = {Kegelmann, Lukas}, title = {Advancing charge selective contacts for efficient monolithic perovskite-silicon tandem solar cells}, doi = {10.25932/publishup-42642}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-426428}, school = {Universit{\"a}t Potsdam}, pages = {v, 155}, year = {2019}, abstract = {Hybrid organic-inorganic perovskites are one of the most promising material classes for photovoltaic energy conversion. In solar cells, the perovskite absorber is sandwiched between n- and p-type contact layers which selectively transport electrons and holes to the cell's cathode and anode, respectively. This thesis aims to advance contact layers in perovskite solar cells and unravel the impact of interface and contact properties on the device performance. Further, the contact materials are applied in monolithic perovskite-silicon heterojunction (SHJ) tandem solar cells, which can overcome the single junction efficiency limits and attract increasing attention. Therefore, all contact layers must be highly transparent to foster light harvesting in the tandem solar cell design. Besides, the SHJ device restricts processing temperatures for the selective contacts to below 200°C. A comparative study of various electron selective contact materials, all processed below 180°C, in n-i-p type perovskite solar cells highlights that selective contacts and their interfaces to the absorber govern the overall device performance. Combining fullerenes and metal-oxides in a TiO2/PC60BM (phenyl-C60-butyric acid methyl ester) double-layer contact allows to merge good charge extraction with minimized interface recombination. The layer sequence thereby achieved high stabilized solar cell performances up to 18.0\% and negligible current-voltage hysteresis, an otherwise pronounced phenomenon in this device design. Double-layer structures are therefore emphasized as a general concept to establish efficient and highly selective contacts. Based on this success, the concept to combine desired properties of different materials is transferred to the p-type contact. Here, a mixture of the small molecule Spiro-OMeTAD [2,2',7,7'-tetrakis(N,N-di-p-methoxyphenylamine)-9,9'-spirobifluoren] and the doped polymer PEDOT [poly(3,4-ethylenedioxythiophene)] is presented as a novel hole selective contact. PEDOT thereby remarkably suppresses charge recombination at the perovskite surface, allowing an increase of quasi-Fermi level splitting in the absorber. Further, the addition of Spiro-OMeTAD into the PEDOT layer is shown to enhance charge extraction at the interface and allow high efficiencies up to 16.8\%. Finally, the knowledge on contact properties is applied to monolithic perovskite-SHJ tandem solar cells. The main goal is to optimize the top contact stack of doped Spiro-OMeTAD/molybdenum oxide(MoOx)/ITO towards higher transparency by two different routes. First, fine-tuning of the ITO deposition to mitigate chemical reduction of MoOx and increase the transmittance of MoOx/ITO stacks by 25\%. Second, replacing Spiro-OMeTAD with the alternative hole transport materials PEDOT/Spiro-OMeTAD mixtures, CuSCN or PTAA [poly(triaryl amine)]. Experimental results determine layer thickness constrains and validate optical simulations, which subsequently allow to realistically estimate the respective tandem device performances. As a result, PTAA represents the most promising replacement for Spiro-OMeTAD, with a projected increase of the optimum tandem device efficiency for the herein used architecture by 2.9\% relative to 26.5\% absolute. The results also reveal general guidelines for further performance gains of the technology.}, language = {en} } @article{MachlebSeyboth2021, author = {Machleb, Franziska and Seyboth, Margret}, title = {Alles kann besser werden!}, series = {Spektrum Patholinguistik}, journal = {Spektrum Patholinguistik}, number = {14}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-507-1}, issn = {1866-9085}, doi = {10.25932/publishup-51041}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-510412}, pages = {121 -- 137}, year = {2021}, language = {de} } @techreport{RadtkeHartmannNeurothetal.2020, author = {Radtke, Ina and Hartmann, Niklas and Neuroth, Heike and Rothfritz, Laura and Wuttke, Ulrike and Straka, Janine and Zeunert, Miriam and Schneemann, Carsten}, title = {Anforderungserhebung bei den brandenburgischen Hochschulen}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, doi = {10.25932/publishup-48091}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-480914}, pages = {50}, year = {2020}, abstract = {Dieser Bericht nimmt die Institutionalisierung von Forschungsdatenmanagement (FDM) an den staatlichen Hochschulen Brandenburgs in den Blick. Er soll zur Beantwortung der folgenden Fragen beitragen: Warum wird FDM dort institutionalisiert? Wie wird FDM dort institutionalisiert? Welche Herausforderungen f{\"u}r eine weitere Institutionalisierung bestehen und wie kann ihnen begegnet werden? Zur Erhebung des Status Quo und zur Identifikation von Anforderungen und Weiterentwicklungspotenzialen wurde deshalb eine Organisationsuntersuchung durchgef{\"u}hrt. Untersuchung ist neben der Einhaltung wissenschaftlicher und professioneller Standards auch dem Anwendungsbezug der Ergebnisse, deren Anwendbarkeit im Kontext und der Partizipation der Beteiligten verpflichtet. Da es sich um ein f{\"u}r die betrachteten Einrichtungen noch vergleichsweise neues Themengebiet handelt, wurde ein exploratives Forschungsdesign unter Einsatz qualitativer Methoden gew{\"a}hlt. Grundlage der Ergebnisse sind ein Auftaktworkshop unter Beteiligung der Hochschulen, eine Dokumentenanalyse und 16 leitfadengest{\"u}tzte Expert*innen-Interviews auf Arbeits- und Leitungsebene der brandenburgischen Hochschulen. Die Ergebnisse werden anhand von vier Handlungsbereichen strukturiert vorgestellt: Relevanz von FDM und Institutionalisierung an den Hochschulen; Technologie und Infrastruktur; Personal und Qualifizierung; Organisation, Kooperation und Finanzierung. Dabei stellt der Bericht sowohl den Status Quo als auch die Ziele der Hochschulen sowie die W{\"u}nsche an eine Landesinitiative vor.}, subject = {Forschungsdaten}, language = {de} } @article{AscheArnold2020, author = {Asche, Matthias and Arnold, Matthieu}, title = {Anton Schindling (1947-2020)}, series = {Francia : Forschungen zur westeurop{\"a}ischen Geschichte}, journal = {Francia : Forschungen zur westeurop{\"a}ischen Geschichte}, number = {47}, publisher = {Thorbecke}, address = {Ostfildern}, isbn = {978-3-7995-8147-9}, doi = {10.11588/fr.2020.0.75750}, pages = {501 -- 503}, year = {2020}, language = {de} } @article{Leinweber2021, author = {Leinweber, Juliane}, title = {App-Einsatz in der Logop{\"a}die/Sprachtherapie: Strategien und Kriterien}, series = {Spektrum Patholinguistik}, journal = {Spektrum Patholinguistik}, number = {14}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-507-1}, issn = {1866-9085}, doi = {10.25932/publishup-51019}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-510199}, pages = {69 -- 76}, year = {2021}, language = {de} } @book{Taneja2007, author = {Taneja, Preti}, title = {Assimilation, exodus, eradication}, publisher = {Minority Rights Group International}, address = {London}, isbn = {1-904584-60-8}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-bbdig-87}, publisher = {Universit{\"a}t Potsdam}, pages = {40}, year = {2007}, language = {en} } @book{FthenakisGisbertGriebel2007, author = {Fthenakis, Wassilios E. and Gisbert, Kristin and Griebel, Wilfried}, title = {Auf den Anfang kommt es an}, series = {Bildungsforschung}, volume = {16}, journal = {Bildungsforschung}, edition = {Unver{\"a}nd. Nachdr.}, address = {Bonn [u.a.]}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-bbdig-136}, publisher = {Universit{\"a}t Potsdam}, pages = {251}, year = {2007}, language = {de} } @book{StraetzSolbachHolstSolbach2007, author = {Str{\"a}tz, Rainer and Solbach, Regina and Holst-Solbach, Friedemann}, title = {Bildungsh{\"a}user f{\"u}r Kinder von drei bis zehn Jahren}, address = {Berlin}, organization = {Bundesministeriumf{\"u}r Bildung und Forschung (BMBF), Referat {\"O}ffentlichkeitsarbeit}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-bbdig-128}, publisher = {Universit{\"a}t Potsdam}, pages = {142}, year = {2007}, language = {de} } @phdthesis{LopezGarcia2019, author = {L{\´o}pez Garc{\´i}a, Patricia}, title = {Coiled coils as mechanical building blocks}, doi = {10.25932/publishup-42956}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-429568}, school = {Universit{\"a}t Potsdam}, pages = {xi, 130}, year = {2019}, abstract = {The natural abundance of Coiled Coil (CC) motifs in cytoskeleton and extracellular matrix proteins suggests that CCs play an important role as passive (structural) and active (regulatory) mechanical building blocks. CCs are self-assembled superhelical structures consisting of 2-7 α-helices. Self-assembly is driven by hydrophobic and ionic interactions, while the helix propensity of the individual helices contributes additional stability to the structure. As a direct result of this simple sequence-structure relationship, CCs serve as templates for protein design and sequences with a pre-defined thermodynamic stability have been synthesized de novo. Despite this quickly increasing knowledge and the vast number of possible CC applications, the mechanical function of CCs has been largely overlooked and little is known about how different CC design parameters determine the mechanical stability of CCs. Once available, this knowledge will open up new applications for CCs as nanomechanical building blocks, e.g. in biomaterials and nanobiotechnology. With the goal of shedding light on the sequence-structure-mechanics relationship of CCs, a well-characterized heterodimeric CC was utilized as a model system. The sequence of this model system was systematically modified to investigate how different design parameters affect the CC response when the force is applied to opposing termini in a shear geometry or separated in a zipper-like fashion from the same termini (unzip geometry). The force was applied using an atomic force microscope set-up and dynamic single-molecule force spectroscopy was performed to determine the rupture forces and energy landscape properties of the CC heterodimers under study. Using force as a denaturant, CC chain separation is initiated by helix uncoiling from the force application points. In the shear geometry, this allows uncoiling-assisted sliding parallel to the force vector or dissociation perpendicular to the force vector. Both competing processes involve the opening of stabilizing hydrophobic (and ionic) interactions. Also in the unzip geometry, helix uncoiling precedes the rupture of hydrophobic contacts. In a first series of experiments, the focus was placed on canonical modifications in the hydrophobic core and the helix propensity. Using the shear geometry, it was shown that both a reduced core packing and helix propensity lower the thermodynamic and mechanical stability of the CC; however, with different effects on the energy landscape of the system. A less tightly packed hydrophobic core increases the distance to the transition state, with only a small effect on the barrier height. This originates from a more dynamic and less tightly packed core, which provides more degrees of freedom to respond to the applied force in the direction of the force vector. In contrast, a reduced helix propensity decreases both the distance to the transition state and the barrier height. The helices are 'easier' to unfold and the remaining structure is less thermodynamically stable so that dissociation perpendicular to the force axis can occur at smaller deformations. Having elucidated how canonical sequence modifications influence CC mechanics, the pulling geometry was investigated in the next step. Using one and the same sequence, the force application points were exchanged and two different shear and one unzipping geometry were compared. It was shown that the pulling geometry determines the mechanical stability of the CC. Different rupture forces were observed in the different shear as well as in the unzipping geometries, suggesting that chain separation follows different pathways on the energy landscape. Whereas the difference between CC shearing and unzipping was anticipated and has also been observed for other biological structures, the observed difference for the two shear geometries was less expected. It can be explained with the structural asymmetry of the CC heterodimer. It is proposed that the direction of the α-helices, the different local helix propensities and the position of a polar asparagine in the hydrophobic core are responsible for the observed difference in the chain separation pathways. In combination, these factors are considered to influence the interplay between processes parallel and perpendicular to the force axis. To obtain more detailed insights into the role of helix stability, helical turns were reinforced locally using artificial constraints in the form of covalent and dynamic 'staples'. A covalent staple bridges to adjacent helical turns, thus protecting them against uncoiling. The staple was inserted directly at the point of force application in one helix or in the same terminus of the other helix, which did not experience the force directly. It was shown that preventing helix uncoiling at the point of force application reduces the distance to the transition state while slightly increasing the barrier height. This confirms that helix uncoiling is critically important for CC chain separation. When inserted into the second helix, this stabilizing effect is transferred across the hydrophobic core and protects the force-loaded turns against uncoiling. If both helices were stapled, no additional increase in mechanical stability was observed. When replacing the covalent staple with a dynamic metal-coordination bond, a smaller decrease in the distance to the transition was observed, suggesting that the staple opens up while the CC is under load. Using fluorinated amino acids as another type of non-natural modification, it was investigated how the enhanced hydrophobicity and the altered packing at the interface influences CC mechanics. The fluorinated amino acid was inserted into one central heptad of one or both α-helices. It was shown that this substitution destabilized the CC thermodynamically and mechanically. Specifically, the barrier height was decreased and the distance to the transition state increased. This suggests that a possible stabilizing effect of the increased hydrophobicity is overruled by a disturbed packing, which originates from a bad fit of the fluorinated amino acid into the local environment. This in turn increases the flexibility at the interface, as also observed for the hydrophobic core substitution described above. In combination, this confirms that the arrangement of the hydrophobic side chains is an additional crucial factor determining the mechanical stability of CCs. In conclusion, this work shows that knowledge of the thermodynamic stability alone is not sufficient to predict the mechanical stability of CCs. It is the interplay between helix propensity and hydrophobic core packing that defines the sequence-structure-mechanics relationship. In combination, both parameters determine the relative contribution of processes parallel and perpendicular to the force axis, i.e. helix uncoiling and uncoiling-assisted sliding as well as dissociation. This new mechanistic knowledge provides insight into the mechanical function of CCs in tissues and opens up the road for designing CCs with pre-defined mechanical properties. The library of mechanically characterized CCs developed in this work is a powerful starting point for a wide spectrum of applications, ranging from molecular force sensors to mechanosensitive crosslinks in protein nanostructures and synthetic extracellular matrix mimics.}, language = {en} }