@misc{LadwigZhouXuetal.2018,
  author    = {Ladwig, Simon and Zhou, Zien and Xu, Ying and Wang, Xia and Chow, Clara K. and Werheid, Katja and Hackett, Maree L.},
  title     = {Comparison of treatment rates of depression after stroke versus myocardial infarction},
  series = {Psychosomatic medicine},
  volume    = {80},
  journal   = {Psychosomatic medicine},
  number    = {8},
  publisher = {Lippincott Williams \& Wilkins},
  address   = {Philadelphia},
  issn      = {0033-3174},
  doi       = {10.1097/PSY.0000000000000632},
  pages     = {754 -- 763},
  year      = {2018},
  abstract  = {Objective Depression after stroke and myocardial infarction (MI) is common but often assumed to be undertreated without reliable evidence being available. Thus, we aimed to determine treatment rates and investigate the application of guidelines in these conditions. Methods Databases MEDLINE, EMBASE, PsycInfo, Web of Science, CINAHL, and Scopus were systematically searched without language restriction from inception to June 30, 2017. Prospective observational studies with consecutive recruitment reporting any antidepressant treatment in adults with depression after stroke or MI were included. Random-effects models were used to calculate pooled estimates of treatment rates. Results Fifty-five studies reported 32 stroke cohorts (n = 8938; pooled frequency of depression = 34\%, 95\% confidence interval [CI] = 29\%-38\%) and 17 MI cohorts (n = 10,767; pooled frequency of depression = 24\%, 95\% CI = 20\%-28\%). In 29 stroke cohorts, 24\% (95\% CI = 20\%-27\%) of 2280 depressed people used antidepressant medication. In 15 MI cohorts, 14\% (95\% CI = 8\%-19\%) of 2381 depressed people used antidepressant medication indicating a lower treatment rate than in stroke. Two studies reported use of psychosocial interventions, indicating that less than 10\% of participants were treated. Conclusions Despite the high frequency of depression after stroke and MI and the existence of efficacious treatment strategies, people often remain untreated. Innovative strategies are needed to increase the use of effective antidepressive interventions in patients with cardiovascular disease.},
  language  = {en}
}
@article{XuZhouMetzleretal.2020,
  author    = {Xu, Pengbo and Zhou, Tian and Metzler, Ralf and Deng, Weihua},
  title     = {L{\´e}vy walk dynamics in an external harmonic potential},
  series = {Physical review : E, Statistical, nonlinear, and soft matter physics},
  volume    = {101},
  journal   = {Physical review : E, Statistical, nonlinear, and soft matter physics},
  number    = {6},
  publisher = {American Physical Society},
  address   = {College Park},
  issn      = {2470-0045},
  doi       = {10.1103/PhysRevE.101.062127},
  pages     = {12},
  year      = {2020},
  abstract  = {Levy walks (LWs) are spatiotemporally coupled random-walk processes describing superdiffusive heat conduction in solids, propagation of light in disordered optical materials, motion of molecular motors in living cells, or motion of animals, humans, robots, and viruses. We here investigate a key feature of LWs-their response to an external harmonic potential. In this generic setting for confined motion we demonstrate that LWs equilibrate exponentially and may assume a bimodal stationary distribution. We also show that the stationary distribution has a horizontal slope next to a reflecting boundary placed at the origin, in contrast to correlated superdiffusive processes. Our results generalize LWs to confining forces and settle some longstanding puzzles around LWs.},
  language  = {en}
}
@misc{XuZhouMetzleretal.2022,
  author    = {Xu, Pengbo and Zhou, Tian and Metzler, Ralf and Deng, Weihua},
  title     = {Stochastic harmonic trapping of a L{\´e}vy walk: transport and first-passage dynamics under soft resetting strategies},
  series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-56040},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-560402},
  pages     = {1 -- 28},
  year      = {2022},
  abstract  = {We introduce and study a L{\´e}vy walk (LW) model of particle spreading with a finite propagation speed combined with soft resets, stochastically occurring periods in which an harmonic external potential is switched on and forces the particle towards a specific position. Soft resets avoid instantaneous relocation of particles that in certain physical settings may be considered unphysical. Moreover, soft resets do not have a specific resetting point but lead the particle towards a resetting point by a restoring Hookean force. Depending on the exact choice for the LW waiting time density and the probability density of the periods when the harmonic potential is switched on, we demonstrate a rich emerging response behaviour including ballistic motion and superdiffusion. When the confinement periods of the soft-reset events are dominant, we observe a particle localisation with an associated non-equilibrium steady state. In this case the stationary particle probability density function turns out to acquire multimodal states. Our derivations are based on Markov chain ideas and LWs with multiple internal states, an approach that may be useful and flexible for the investigation of other generalised random walks with soft and hard resets. The spreading efficiency of soft-rest LWs is characterised by the first-passage time statistic.},
  language  = {en}
}
@article{ZhangXuGaillardetal.2016,
  author    = {Zhang, Shengrui and Xu, Qinghai and Gaillard, Marie-Jose and Cao, Xianyong and Li, Jianyong and Zhang, Liyan and Li, Yuecong and Tian, Fang and Zhou, Liping and Lin, Fengyou and Yang, Xiaolan},
  title     = {Characteristic pollen source area and vertical pollen dispersal and deposition in a mixed coniferous and deciduous broad-leaved woodland in the Changbai mountains, northeast China},
  series = {Vegetation History and Archaeobotany},
  volume    = {25},
  journal   = {Vegetation History and Archaeobotany},
  publisher = {Springer},
  address   = {New York},
  issn      = {0939-6314},
  doi       = {10.1007/s00334-015-0532-0},
  pages     = {29 -- 43},
  year      = {2016},
  abstract  = {Pollen influx (number of pollen grains cm\&\#8722;2 year\&\#8722;1) can objectively reflect the dispersal and deposition features of pollen within a certain time and space, and is often used as a basis for the quantitative reconstruction of palaeovegetation; however, little is known about the features and mechanisms of vertical dispersal of pollen. Here we present the results from a 5 year (2006-2010) monitoring program using pollen traps placed at different heights from ground level up to 60 m and surface soil samples in a mixed coniferous and deciduous broad-leaved woodland in the Changbai mountains, northeastern China. The pollen percentages and pollen influx from the traps have very similar characteristics to the highest values for Betula, Fraxinus, Quercus and Pinus, among the tree taxa and Artemisia, Chenopodiaceae and Asteraceae among the herb taxa. Pollen influx values vary significantly with height and show major differences between three distinct layers, above-canopy (\&\#8805;32 m), within the trunk layer (8 \&\#8804; 32 m) and on the ground (0 m). These differences in pollen influx are explained by differences in (i) the air flows in each of these layers and (ii) the fall speed of pollen of the various taxa. We found that the pollen recorded on the ground surface is a good representation of the major part of the pollen transported in the trunk space of the woodland. Comparison of the pollen influx values with the theoretical, calculated "characteristic pollen source area" (CPSA) of 12 selected taxa indicates that the pollen deposited on the ground surface of the woodland is a fair representation with 85-90 \% of the total pollen deposited at a wind speed of 2.4 m s\&\#8722;1 coming from within ca. 1-5 km for Pinus and Quercus, ca. 5-10 km for Ulmus, Tilia, Oleaceae and Betula, ca. 20-40 km for Fraxinus, Poaceae, Chenopodiaceae, Populus and Salix, and ca. 30-60 km for Artemisia; it is also a good representation with 90-98 \% of the total pollen deposited coming from within 60 km at a wind speed of 2.4 m s\&\#8722;1, or 100 km at a wind speed: 6 m s\&\#8722;1, for the 12 selected taxa used in the CPSA calculation. Furthermore, comparison with the vegetation map of the area around the sampling site shows that the pollen deposited on the ground represents all plant communities which grow in the study area within 70 km radius of the sampling site. In this study, the pollen percentages obtained from the soil surface samples are significantly biased towards pollen taxa with good preservation due to thick and robust pollen walls. Therefore, if mosses are available instead, soil samples should be avoided for pollen studies, in particular for the study of pollen-vegetation relationships, the estimation of pollen productivities and quantitative reconstruction of past vegetation. The results also indicate that the existing model of pollen dispersal and deposition, Prentice's model, provides a fair description of the actual pollen dispersal and deposition in this kind of woodland, which suggests that the application of the landscape reconstruction algorithm would be relevant for reconstruction of this type of woodland in the past.},
  language  = {en}
}
@phdthesis{Zhou2014,
  author    = {Zhou, Xu},
  title     = {Atmospheric interactions with land surface in the arctic based on regional climate model solutions},
  pages     = {143},
  year      = {2014},
  language  = {en}
}
@article{XuZhouMetzleretal.2022,
  author    = {Xu, Pengbo and Zhou, Tian and Metzler, Ralf and Deng, Weihua},
  title     = {Stochastic harmonic trapping of a L{\´e}vy walk},
  series = {New journal of physics : the open-access journal for physics / Deutsche Physikalische Gesellschaft ; IOP, Institute of Physics},
  volume    = {24},
  journal   = {New journal of physics : the open-access journal for physics / Deutsche Physikalische Gesellschaft ; IOP, Institute of Physics},
  number    = {3},
  publisher = {Deutsche Physikalische Gesellschaft},
  address   = {Bad Honnef},
  issn      = {1367-2630},
  doi       = {10.1088/1367-2630/ac5282},
  pages     = {1 -- 28},
  year      = {2022},
  abstract  = {We introduce and study a L{\´e}vy walk (LW) model of particle spreading with a finite propagation speed combined with soft resets, stochastically occurring periods in which an harmonic external potential is switched on and forces the particle towards a specific position. Soft resets avoid instantaneous relocation of particles that in certain physical settings may be considered unphysical. Moreover, soft resets do not have a specific resetting point but lead the particle towards a resetting point by a restoring Hookean force. Depending on the exact choice for the LW waiting time density and the probability density of the periods when the harmonic potential is switched on, we demonstrate a rich emerging response behaviour including ballistic motion and superdiffusion. When the confinement periods of the soft-reset events are dominant, we observe a particle localisation with an associated non-equilibrium steady state. In this case the stationary particle probability density function turns out to acquire multimodal states. Our derivations are based on Markov chain ideas and LWs with multiple internal states, an approach that may be useful and flexible for the investigation of other generalised random walks with soft and hard resets. The spreading efficiency of soft-rest LWs is characterised by the first-passage time statistic.},
  language  = {en}
}
@article{ZhouZengFuetal.2016,
  author    = {Zhou, Ying and Zeng, Lanting and Fu, Xiumin and Mei, Xin and Cheng, Sihua and Liao, Yinyin and Deng, Rufang and Xu, Xinlan and Jiang, Yueming and Duan, Xuewu and Baldermann, Susanne and Yang, Ziyin},
  title     = {The sphingolipid biosynthetic enzyme Sphingolipid delta8 desaturase is important for chilling resistance of tomato},
  series = {Scientific reports},
  volume    = {6},
  journal   = {Scientific reports},
  publisher = {Nature Publ. Group},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/srep38742},
  pages     = {10},
  year      = {2016},
  abstract  = {The physiological functions of sphingolipids in animals have been intensively studied, while less attention has been paid to their roles in plants. Here, we reveal the involvement of sphingolipid delta8 desaturase (SlSLD) in the chilling resistance of tomato (Solanum lycopersicum cv. Micro-Tom). We used the virus-induced gene silencing (VIGS) approach to knock-down SlSLD expression in tomato leaves, and then evaluated chilling resistance. Changes in leaf cell structure under a chilling treatment were observed by transmission electron microscopy. In control plants, SlSLD was highly expressed in the fruit and leaves in response to a chilling treatment. The degree of chilling damage was greater in SlSLD-silenced plants than in control plants, indicating that SlSLD knock-down significantly reduced the chilling resistance of tomato. Compared with control plants, SlSLD-silenced plants showed higher relative electrolytic leakage and malondialdehyde content, and lower superoxide dismutase and peroxidase activities after a chilling treatment. Chilling severely damaged the chloroplasts in SlSLD-silenced plants, resulting in the disruption of chloroplast membranes, swelling of thylakoids, and reduced granal stacking. Together, these results show that SlSLD is crucial for chilling resistance in tomato.},
  language  = {en}
}
@article{ZhouXuMaetal.2021,
  author    = {Zhou, Shuo and Xu, Xun and Ma, Nan and Jung, Friedrich and Lendlein, Andreas},
  title     = {Influence of sterilization conditions on sulfate-functionalized polyGGE},
  series = {Clinical hemorheology and microcirculation : blood flow and vessels},
  volume    = {79},
  journal   = {Clinical hemorheology and microcirculation : blood flow and vessels},
  number    = {4},
  publisher = {IOS Press},
  address   = {Amsterdam},
  issn      = {1386-0291},
  doi       = {10.3233/CH-211241},
  pages     = {597 -- 608},
  year      = {2021},
  abstract  = {Sulfated biomolecules are known to influence numerous biological processes in all living organisms. Particularly, they contribute to prevent and inhibit the hypercoagulation condition. The failure of polymeric implants and blood contacting devices is often related to hypercoagulation and microbial contamination. Here, bioactive sulfated biomacromolecules are mimicked by sulfation of poly(glycerol glycidyl ether) (polyGGE) films. Autoclaving, gamma-ray irradiation and ethylene oxide (EtO) gas sterilization techniques were applied to functionalized materials. The sulfate group density and hydrophilicity of sulfated polymers were decreased while chain mobility and thermal degradation were enhanced post autoclaving when compared to those after EtO sterilization. These results suggest that a quality control after sterilization is mandatory to ensure the amount and functionality of functionalized groups are retained.},
  language  = {en}
}
@article{TaoSuXuetal.2018,
  author    = {Tao, Ting and Su, Qiongli and Xu, Simeng and Deng, Jun and Zhou, Sichun and Zhuang, Yu and Huang, Yanjun and He, Caimei and He, Shanping and Peng, Mei and Hocher, Berthold and Yang, Xiaoping},
  title     = {Down-regulation of PKM2 decreases FASN expression in bladder cancer cells through AKT/mTOR/SREBP-1c axis},
  series = {Journal of cellular physiology},
  volume    = {234},
  journal   = {Journal of cellular physiology},
  number    = {3},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {0021-9541},
  doi       = {10.1002/jcp.27129},
  pages     = {3088 -- 3104},
  year      = {2018},
  abstract  = {Fatty acid synthase (FASN) catalyzing the terminal steps in the de novo biogenesis of fatty acids is correlated with low survival and high disease recurrence in patients with bladder cancer. Pyruvate kinase M2 (PKM2) regulates the final step of glycolysis levels and provides a growth advantage to tumors. However, it is unclear whether the change of PKM2 has an effect on FASN and what is the mechanisms underlying. Here we describe a novel function of PKM2 in control of lipid metabolism by mediating transcriptional activation of FASN, showing the reduced expression of sterol regulatory element binding protein 1c (SREBP-1c). We first discovered that PKM2 physically interacts with the SREBP-1c using biochemical approaches, and downregulation of PKM2 reduced the expression of SREBP-1c by inactivating the AKT/mTOR signaling pathway, which in turn directly suppressed the transcription of major lipogenic genes FASN to reduce tumor growths. Furthermore, either PKM2 inhibitor-Shikonin or FASN inhibitor-TVB-3166 alone induced a strong antiproliferative and anticolony forming effect in bladder cancer cell line. The combination of both inhibitors exhibits a super synergistic effect on blocking the bladder cancer cells growth. It provides a new target and scientific basis for the treatment of bladder cancer.},
  language  = {en}
}