@misc{VoigtZimmermannStierLascheitetal.2019, author = {Voigt-Zimmermann, Susanne and Stier, Karl-Heinz and Lascheit, Thomas and Kruse, Stephanie A. and Blickensdorff, Maria and F{\"o}rster, Theresa and Schumacher, Rebecca and Burchert, Frank and Ablinger, Irene and F{\"o}rster, Christine and Wahl, Michael and Schirmacher, Irene and Ostermann, Frank and Welke, Lisa-Marie and Frank, Ulrike and Zakari{\´a}s, Lilla and Salis, Christos and Wartenburger, Isabell and Krug, Ragna and St{\"u}bner, Hanna and Hoffmann, Sophie and Heide, Judith}, title = {Spektrum Patholinguistik Band 11. Schwerpunktthema: Gut gestimmt: Diagnostik und Therapie bei Dysphonie}, number = {11}, editor = {Fritzsche, Tom and Yetim, {\"O}zlem and Otto, Constanze and Adelt, Anne}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-448-7}, issn = {1866-9085}, doi = {10.25932/publishup-41857}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-418574}, pages = {142}, year = {2019}, abstract = {Das 11. Herbsttreffen Patholinguistik mit dem Schwerpunktthema »Gut gestimmt: Diagnostik und Therapie bei Dysphonie« fand am 18.11.2017 in Potsdam statt. Das Herbsttreffen wird seit 2007 j{\"a}hrlich vom Verband f{\"u}r Patholinguistik e.V. (vpl) durchgef{\"u}hrt. Der vorliegende Tagungsband beinhaltet die Hauptvortr{\"a}ge zum Schwerpunktthema sowie Beitr{\"a}ge zu den Kurzvortr{\"a}gen »Spektrum Patholinguistik« und der Posterpr{\"a}sentationen zu weiteren Themen aus der sprachtherapeutischen Forschung und Praxis.}, language = {de} } @article{MehnertAkhrifTelkemeyeretal.2013, author = {Mehnert, Jan and Akhrif, Atae and Telkemeyer, Silke and Rossi, Sonja and Schmitz, Christoph H. and Steinbrink, Jens and Wartenburger, Isabell and Obrig, Hellmuth and Neufang, Susanne}, title = {Developmental changes in brain activation and functional connectivity during response inhibition in the early childhood brain}, series = {Brain and development : official journal of the Japanese Society of Child Neurology}, volume = {35}, journal = {Brain and development : official journal of the Japanese Society of Child Neurology}, number = {10}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0387-7604}, doi = {10.1016/j.braindev.2012.11.006}, pages = {894 -- 904}, year = {2013}, abstract = {Response inhibition is an attention function which develops relatively early during childhood. Behavioral data suggest that by the age of 3, children master the basic task requirements for the assessment of response inhibition but performance improves substantially until the age of 7. The neuronal mechanisms underlying these developmental processes, however, are not well understood. In this study, we examined brain activation patterns and behavioral performance of children aged between 4 and 6 years compared to adults by applying a go/no-go paradigm during near-infrared spectroscopy (NIRS) brain imaging. We furthermore applied task-independent functional connectivity measures to the imaging data to identify maturation of intrinsic neural functional networks. We found a significant group x condition related interaction in terms of inhibition-related reduced right fronto-parietal activation in children compared to adults. In contrast, motor-related activation did not differ between age groups. Functional connectivity analysis revealed that in the children's group, short-range coherence within frontal areas was stronger, and long-range coherence between frontal and parietal areas was weaker, compared to adults. Our findings show that in children aged from 4 to 6 years fronto-parietal brain maturation plays a crucial part in the cognitive development of response inhibition.}, language = {en} } @article{TelkemeyerRossiKochetal.2009, author = {Telkemeyer, Silke and Rossi, Sonja and Koch, Stefan P. and Nierhaus, Till and Steinbrink, Jens and Poeppel, David and Obrig, Hellmuth and Wartenburger, Isabell}, title = {Sensitivity of newborn auditory cortex to the temporal structure of sounds}, issn = {0270-6474}, doi = {10.1523/Jneurosci.1246-09.2009}, year = {2009}, abstract = {Understanding the rapidly developing building blocks of speech perception in infancy requires a close look at the auditory prerequisites for speech sound processing. Pioneering studies have demonstrated that hemispheric specializations for language processing are already present in early infancy. However, whether these computational asymmetries can be considered a function of linguistic attributes or a consequence of basic temporal signal properties is under debate. Several studies in adults link hemispheric specialization for certain aspects of speech perception to an asymmetry in cortical tuning and reveal that the auditory cortices are differentially sensitive to spectrotemporal features of speech. Applying concurrent electrophysiological (EEG) and hemodynamic (near-infrared spectroscopy) recording to newborn infants listening to temporally structured nonspeech signals, we provide evidence that newborns process nonlinguistic acoustic stimuli that share critical temporal features with language in a differential manner. The newborn brain preferentially processes temporal modulations especially relevant for phoneme perception. In line with multi-time-resolution conceptions, modulations on the time scale of phonemes elicit strong bilateral cortical responses. Our data furthermore suggest that responses to slow acoustic modulations are lateralized to the right hemisphere. That is, the newborn auditory cortex is sensitive to the temporal structure of the auditory input and shows an emerging tendency for functional asymmetry. Hence, our findings support the hypothesis that development of speech perception is linked to basic capacities in auditory processing. From birth, the brain is tuned to critical temporal properties of linguistic signals to facilitate one of the major needs of humans: to communicate.}, language = {en} } @article{PassowMuellerWesterhausenetal.2013, author = {Passow, Susanne and M{\"u}ller, Maike and Westerhausen, Rene and Hugdahl, Kenneth and Wartenburger, Isabell and Heekeren, Hauke R. and Lindenberger, Ulman and Li, Shu-Chen}, title = {Development of attentional control of verbal auditory perception from middle to late childhood - comparisons to healthy aging}, series = {Developmental psychology}, volume = {49}, journal = {Developmental psychology}, number = {10}, publisher = {American Psychological Association}, address = {Washington}, issn = {0012-1649}, doi = {10.1037/a0031207}, pages = {1982 -- 1993}, year = {2013}, abstract = {Multitalker situations confront listeners with a plethora of competing auditory inputs, and hence require selective attention to relevant information, especially when the perceptual saliency of distracting inputs is high. This study augmented the classical forced-attention dichotic listening paradigm by adding an interaural intensity manipulation to investigate developmental differences in the interplay between perceptual saliency and attentional control during auditory processing between early and middle childhood. We found that older children were able to flexibly focus on instructed auditory inputs from either the right or the left ear, overcoming the effects of perceptual saliency. In contrast, younger children implemented their attentional focus less efficiently. Direct comparisons of the present data with data from a recently published study of younger and older adults from our group suggest that younger children and older adults show similar levels of performance. Critically, follow-up comparisons revealed that younger children's performance restrictions reflect difficulties in attentional control only, whereas older adults' performance deficits also reflect an exaggerated reliance on perceptual saliency. We conclude that auditory attentional control improves considerably from middle to late childhood and that auditory attention deficits in healthy aging cannot be reduced to a simple reversal of child developmental improvements.}, language = {en} } @article{WartenburgerKuehnSassenbergetal.2010, author = {Wartenburger, Isabell and K{\"u}hn, Esther and Sassenberg, Uta and Foth, Manja and Franz, Elisabeth A. and van der Meer, Elke}, title = {On the relationship between fluid intelligence, gesture production, and brain structure}, issn = {0160-2896}, doi = {10.1016/j.intell.2009.11.001}, year = {2010}, abstract = {Individuals scoring high in fluid intelligence tasks generally perform very efficiently in problem solving tasks and analogical reasoning tasks presumably because they are able to select the task-relevant information very quickly and focus on a limited set of task-relevant cognitive operations. Moreover, individuals with high fluid intelligence produce more representational hand and arm gestures when describing a geometric analogy task than individuals with average fluid intelligence. No study has yet addressed the relationship between intelligence, gesture production, and brain structure, to our knowledge. That was the purpose of our study. To characterize the relation between intelligence, gesture production, and brain structure we assessed the frequency of representational gestures and cortical thickness values in a group of adolescents differing in fluid intelligence. Individuals scoring high in fluid intelligence showed higher accuracy in the geometric analogy task and produced more representational gestures (in particular more movement gestures) when explaining how they solved the task and showed larger cortical thickness values in some regions in the left hemisphere (namely the pars opercularis, superior frontal, and temporal cortex) than individuals with average fluid intelligence. Moreover, the left pars opercularis (a part of Broca's area) and left transverse temporal cortex showed larger cortical thickness values in participants who produced representational and in particular movement gestures compared to those who did not. Our results thus indicate that cortical thickness of those brain regions is related to both high fluid intelligence and the production of gestures. Results are discussed in the gestures-as-simulated-action framework that states that gestures result from simulated perception and simulated action that underlie embodied language and mental imagery.}, language = {en} } @article{WartenburgerHeekerenPreusseetal.2009, author = {Wartenburger, Isabell and Heekeren, Hauke R. and Preusse, Franziska and Kramer, J{\"u}rg and van der Meer, Elke}, title = {Cerebral correlates of analogical processing and their modulation by training}, issn = {1053-8119}, doi = {10.1016/j.neuroimage.2009.06.025}, year = {2009}, abstract = {There is increasing interest ill understanding the neural systems that mediate analogical thinking, which is essential for learning and fluid intelligence. The aim of the present study was to shed light on the cerebral correlates of geometric analogical processing and on training-induced changes at the behavioral and brain level. In healthy participants a bilateral fronto-parietal network was engaged in processing geometric analogies and showed greater blood oxygenation dependent (BOLD) signals as resource demands increased. This network, as well as fusiform and subcortical brain regions, additionally showed training-induced decreases in the BOLD signal over time. The general finding that brain regions were modulated by the amount of resources demanded by the task, and/or by the reduction of allocated resources due to short term training, reflects increased efficiency - in terms of more focal and more specialized brain activation - to more economically process the geometric analogies. Our data indicate a rapid adaptation of the cognitive system which is efficiently modulated by short term training based on a positive correlation of resource demands and brain activation.}, language = {en} } @article{PrehnWartenburgerMeriauetal.2008, author = {Prehn, Kristin and Wartenburger, Isabell and M{\´e}riau, Katja and Scheibe, Christina and Goodenough, Oliver R. and Villringer, Arno and van der Meer, Elke and Heekeren, Hauke R.}, title = {Individual differences in moral judgment competence influence neural correlates of socio-normative judgments}, issn = {1749-5016}, year = {2008}, language = {en} } @article{vanderMeerBeyerHornetal.2010, author = {van der Meer, Elke and Beyer, Reinhard and Horn, Judith and Foth, Manja and Bornemann, Boris and Ries, Jan and Kramer, J{\"u}rg and Warmuth, Elke and Heekeren, Hauke R. and Wartenburger, Isabell}, title = {Resource allocation and fluid intelligence ; insights from pupillometry}, issn = {0048-5772}, year = {2010}, language = {en} } @article{CannestraWartenburgerObrigetal.2003, author = {Cannestra, Andrew F. and Wartenburger, Isabell and Obrig, Hellmuth and Villringer, Arno and Toga, Arthur W.}, title = {Functional assessment of Broca's area using near infrared spectroscopy in humans}, issn = {0959-4965}, year = {2003}, language = {en} } @article{ScheibeWartenburgerWuestenbergetal.2006, author = {Scheibe, Christina and Wartenburger, Isabell and W{\"u}stenberg, Torsten and Kathmann, Norbert and Villringer, Arno and Heekeren, Hauke R.}, title = {Neural correlates of the interaction between transient and sustained processes : a mixed blocked/event-related fMRI study}, issn = {1065-9471}, year = {2006}, language = {en} }