@misc{SchindlerFrank2012, author = {Schindler, Wencke and Frank, Ulrike}, title = {Wasserschlucktests in der klinischen Dysphagiediagnostik : Einzelschluckvolumen als Pr{\"a}diktor f{\"u}r die sequentielle Schluckrate?}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-62506}, year = {2012}, language = {de} } @book{NasdalaMoebusStockhorstetal.2001, author = {Nasdala, Gerhard and M{\"o}bus, Frank and Stockhorst, Stefanie and M{\"a}lzig, Ulrike}, title = {Wege nach Weimar : Beitr{\"a}ge der Studentenkolloquien im Rahmen des Modellprojekts Weimarer Klassik und Jenaer Romantik 1996/97}, series = {Ver{\"o}ffentlichungen des Studienprogramms Weimarer Klassik und Jenaer Romantik}, volume = {1}, journal = {Ver{\"o}ffentlichungen des Studienprogramms Weimarer Klassik und Jenaer Romantik}, publisher = {Litblock{\´i}n}, address = {Fernwald}, isbn = {3-932289-57-9}, pages = {185 S.}, year = {2001}, language = {de} } @article{OpitzWuennemannAichneretal.2012, author = {Opitz, Stephan and W{\"u}nnemann, Bernd and Aichner, Bernhard and Dietze, Elisabeth and Hartmann, Kai and Herzschuh, Ulrike and IJmker, Janneke and Lehmkuhl, Frank and Li, Shijie and Mischke, Steffen and Plotzki, Anna and Stauch, Georg and Diekmann, Bernhard}, title = {Late Glacial and Holocene development of Lake Donggi Cona, north-eastern Tibetan Plateau, inferred from sedimentological analysis}, series = {Palaeogeography, palaeoclimatology, palaeoecology : an international journal for the geo-sciences}, volume = {337}, journal = {Palaeogeography, palaeoclimatology, palaeoecology : an international journal for the geo-sciences}, number = {23}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0031-0182}, doi = {10.1016/j.palaeo.2012.04.013}, pages = {159 -- 176}, year = {2012}, abstract = {Sediments of Lake Donggi Cona on the northeastern Tibetan Plateau were studied to infer changes in the lacustrine depositional environment, related to climatic and non-climatic changes during the last 19 kyr. The lake today fills a 30x8 km big and 95 m deep tectonic basin, associated with the Kunlun Fault. The study was conducted on a sediment-core transect through the lake basin, in order to gain a complete picture of spatio-temporal environmental change. The recovered sediments are partly finely laminated and are composed of calcareous muds with variable amounts of carbonate micrite, organic matter, detrital silt and clay. On the basis of sedimentological, geochemical, and mineralogical data up to five lithological units (LU) can be distinguished that document distinct stages in the development of the lake system. The onset of the lowermost LU with lacustrine muds above basal sands indicates that lake level was at least 39 m below the present level and started to rise after 19 ka, possibly in response to regional deglaciation. At this time, the lacustrine environment was characterized by detrital sediment influx and the deposition of siliciclastic sediment. In two sediment cores, upward grain-size coarsening documents a lake-level fall after 13 cal ka BP, possibly associated with the late-glacial Younger Dryas stadial. From 11.5 to 4.3 cal ka BP, grain-size fining in sediment cores from the profundal coring sites and the onset of lacustrine deposition at a litoral core site (2 m water depth) in a recent marginal bay of Donggi Cona document lake-level rise during the early to mid-Holocene to at least modern level. In addition, high biological productivity and pronounced precipitation of carbonate micrites are consistent with warm and moist climate conditions related to an enhanced influence of summer monsoon. At 4.3 cal ka BP the lake system shifted from an aragonite- to a calcite-dominated system, indicating a change towards a fully open hydrological lake system. The younger clay-rich sediments are moreover non-laminated and lack any diagenetic sulphides, pointing to fully ventilated conditions, and the prevailing absence of lake stratification. This turning point in lake history could imply either a threshold response to insolation-forced climate cooling or a response to a non-climatic trigger, such as an erosional event or a tectonic pulse that induced a strong earthquake, which is difficult to decide from our data base.}, language = {en} } @article{TianHerzschuhMischkeetal.2014, author = {Tian, Fang and Herzschuh, Ulrike and Mischke, Steffen and Schluetz, Frank}, title = {What drives the recent intensified vegetation degradation in Mongolia - Climate change or human activity?}, series = {The Holocene : an interdisciplinary journal focusing on recent environmental change}, volume = {24}, journal = {The Holocene : an interdisciplinary journal focusing on recent environmental change}, number = {10}, publisher = {Sage Publ.}, address = {London}, issn = {0959-6836}, doi = {10.1177/0959683614540958}, pages = {1206 -- 1215}, year = {2014}, abstract = {This study examines the course and driving forces of recent vegetation change in the Mongolian steppe. A sediment core covering the last 55years from a small closed-basin lake in central Mongolia was analyzed for its multi-proxy record at annual resolution. Pollen analysis shows that highest abundances of planted Poaceae and highest vegetation diversity occurred during 1977-1992, reflecting agricultural development in the lake area. A decrease in diversity and an increase in Artemisia abundance after 1992 indicate enhanced vegetation degradation in recent times, most probably because of overgrazing and farmland abandonment. Human impact is the main factor for the vegetation degradation within the past decades as revealed by a series of redundancy analyses, while climate change and soil erosion play subordinate roles. High Pediastrum (a green algae) influx, high atomic total organic carbon/total nitrogen (TOC/TN) ratios, abundant coarse detrital grains, and the decrease of C-13(org) and N-15 since about 1977 but particularly after 1992 indicate that abundant terrestrial organic matter and nutrients were transported into the lake and caused lake eutrophication, presumably because of intensified land use. Thus, we infer that the transition to a market economy in Mongolia since the early 1990s not only caused dramatic vegetation degradation but also affected the lake ecosystem through anthropogenic changes in the catchment area.}, language = {en} } @misc{CostardStadieRitteretal.2011, author = {Costard, Sylvia and Stadie, Nicole and Ritter, Christiane and Moll, Kristina and Landerl, Karin and Kohnen, Saskia and Kentner, Gerrit and Bethmann, Anja and Scheich, Henning and Brechmann, Andr{\´e} and De Kok, D{\"o}rte and Berger, Frauke and Sticher, Heike and Czepluch, Christine and M{\"a}tzener, Flurina and Wilmes, Stefanie and Hadert, Sandra and Frank, Ulrike and M{\"a}der, Mark and Westermann, Antje and Meinusch, Miriam and Neumann, Sandra and D{\"u}sterh{\"o}ft, Stefanie and Posse, Dorothea and Puritz, Caroline and Seidl, Rainer Ottis and Etzien, Maria and Machleb, Franziska and Lorenz, Antje and H{\"o}ger, Maria and Schr{\"o}der, Astrid and Busch, Tobias and Heide, Judith and Tagoe, Tanja and Watermeyer, Melanie and H{\"o}hle, Barbara and Kauschke, Christina}, title = {Spektrum Patholinguistik = Schwerpunktthema: Lesen lernen: Diagnostik und Therapie bei St{\"o}rungen des Leseerwerbs}, number = {4}, editor = {Hanne, Sandra and Fritzsche, Tom and Ott, Susan and Adelt, Anne}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, organization = {Verband f{\"u}r Patholinguistik e. V. (vpl)}, isbn = {978-3-86956-145-5}, issn = {1869-3822}, doi = {10.25932/publishup-5155}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-53146}, year = {2011}, abstract = {Am 20. November 2010 fand an der Universit{\"a}t Potsdam das 4. Herbsttreffen Patholinguistik statt. Die Konferenzreihe wird regelm{\"a}ßig seit 2007 vom Verband f{\"u}r Patholinguistik e.V. (vpl) durchgef{\"u}hrt. Der vorliegende Tagungsband ver{\"o}ffentlicht die Hauptvortr{\"a}ge des Herbsttreffens zum Thema "Lesen lernen: Diagnostik und Therapie bei St{\"o}rungen des Leseerwerbs". Des Weiteren sind die Beitr{\"a}ge promovierender bzw. promovierter PatholinguistInnen sowie der Posterpr{\"a}sentationen enthalten.}, language = {de} } @misc{vFrankenbergSeidlSchultheissetal.2012, author = {v. Frankenberg, Jenny and Seidl, Rainer Ottis and Schultheiss, Corinna and Frank, Ulrike and Fuß, Sophia and Stefke, Michaela and Honekamp, Andrea and Winkler, Silke and J{\"a}ckel, Annemarie and Schindler, Wencke and Wenglarczyk, Anke and Weise, Stefanie and Heide, Judith and Stadie, Nicole and Schr{\"o}der, Astrid and Baer-Henney, Dinah and van de Vijver, Ruben and Sauerland, Uli and Yatsushiro, Kazuko and Sch{\"o}ppe, Doreen and Blatter, Kristine and Faust, Verena and J{\"a}ger, Dana and Artelt, Cordula and Schneider, Wolfgang and Stanat, Petra and Bruchm{\"u}ller, Wiebke and Sj{\"o}str{\"o}m, Saana and Sch{\"u}tz, Susann and Swietza, Romy and Zielina, Marie and Freymann, Marie and Hausmann, Nadin and K{\"o}ntopp, Isabelle and Liebig, Johanna and Schnell, Annemarie and Wegener, Viktoria and Heinemann, Steffi and Haensel, Diana and M{\"u}rbe, Dirk and Pomnitz, Patricia and Siegm{\"u}ller, Julia}, title = {Spektrum Patholinguistik = Schwerpunktthema: Schluck f{\"u}r Schluck: Dysphagietherapie bei Kindern und Erwachsenen}, number = {5}, editor = {Heide, Judith and Fritzsche, Tom and Meyer, Corinna B. and Ott, Susan}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, organization = {Verband f{\"u}r Patholinguistik e.V.}, isbn = {978-3-86956-199-8}, issn = {1866-9433}, doi = {10.25932/publishup-5866}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-59877}, year = {2012}, abstract = {Das Herbsttreffen Patholinguistik wird seit 2007 j{\"a}hrlich vom Verband f{\"u}r Patholinguistik e.V. (vpl) durchgef{\"u}hrt. Die Jubil{\"a}umsveranstaltung am 19.11.2011 in Potsdam war nicht nur die 5. Auflage der Veranstaltung, sondern auch ein Fest zum 10j{\"a}hrigen Bestehen des Verbandes. Das Thema lautete "Schluck f{\"u}r Schluck: Dysphagietherapie bei Kindern und Erwachsenen". Im vorliegenden Tagungsband finden sich die Artikel der Hauptvortr{\"a}ge sowie die Abstracts der Posterpr{\"a}sentationen.}, language = {de} } @article{SchirrmeisterMeyerAndreevetal.2016, author = {Schirrmeister, Lutz and Meyer, Hanno and Andreev, Andrei and Wetterich, Sebastian and Kienast, Frank and Bobrov, Anatoly and Fuchs, Margret and Sierralta, Melanie and Herzschuh, Ulrike}, title = {Late Quaternary paleoenvironmental records from the Chatanika River valley near Fairbanks (Alaska)}, series = {Quaternary science reviews : the international multidisciplinary research and review journal}, volume = {147}, journal = {Quaternary science reviews : the international multidisciplinary research and review journal}, publisher = {Elsevier}, address = {Oxford}, issn = {0277-3791}, doi = {10.1016/j.quascirev.2016.02.009}, pages = {259 -- 278}, year = {2016}, abstract = {Perennially-frozen deposits are considered as excellent paleoenvironmental archives similar to lacustrine, deep marine, and glacier records because of the long-term and good preservation of fossil records under stable permafrost conditions. A permafrost tunnel in the Vault Creek Valley (Chatanika River Valley, near Fairbanks) exposes a sequence of frozen deposits and ground ice that provides a comprehensive set of proxies to reconstruct the late Quaternary environmental history of Interior Alaska. The multi-proxy approach includes different dating techniques (radiocarbon-accelerator mass spectrometry [AMS C-14], optically stimulated luminescence [OSL], thorium/uranium radioisotope disequilibria [Th-230/U]), as well as methods of sedimentology, paleoecology, hydrochemistry, and stable isotope geochemistry of ground ice. The studied sequence consists of 36-m-thick late Quaternary deposits above schistose bedrock. Main portions of the sequence accumulated during the early and middle Wisconsin periods. The lowermost unit A consists of about 9-m-thick ice-bonded fluvial gravels with sand and peat lenses. A late Sangamon (MIS 5a) age of unit A is assumed. Spruce forest with birch, larch, and some shrubby alder dominated the vegetation. High presence of Sphagnum spores and Cyperaceae pollen points to mires in the Vault Creek Valley. The overlying unit B consists of 10-m-thick alternating fluvial gravels, loess-like silt, and sand layers, penetrated by small ice wedges. OSL dates support a stadial early Wisconsin (MIS 4) age of unit B. Pollen and plant macrofossil data point to spruce forests with some birch interspersed with wetlands around the site. The following unit C is composed of 15-m-thick ice-rich loess-like and organic-rich silt with fossil bones and large ice wedges. Unit C formed during the interstadial mid-Wisconsin (MIS 3) and stadial late Wisconsin (MIS 2) as indicated by radiocarbon ages. Post-depositional slope processes significantly deformed both, ground ice and sediments of unit C. Pollen data show that spruce forests and wetlands dominated the area. The macrofossil remains of Picea, Larix, and Alnus incana ssp. tenuifolia also prove the existence of boreal coniferous forests during the mid-Wisconsin interstadial, which were replaced by treeless tundra-steppe vegetation during the late Wisconsin stadial. Unit C is discordantly overlain by the 2-m-thick late Holocene deposits of unit D. The pollen record of unit D indicates boreal forest vegetation similar to the modern one. The permafrost record from the Vault Creek tunnel reflects more than 90 ka of periglacial landscape dynamics triggered by fluvial and eolian accumulation, and formation of ice-wedge polygons and post depositional deformation by slope processes. The record represents a typical Wisconsin valley-bottom facies in Central Alaska. (C) 2016 Elsevier Ltd. All rights reserved.}, language = {en} } @article{DunkerBoydDurkaetal.2022, author = {Dunker, Susanne and Boyd, Matthew and Durka, Walter and Erler, Silvio and Harpole, W. Stanley and Henning, Silvia and Herzschuh, Ulrike and Hornick, Thomas and Knight, Tiffany and Lips, Stefan and M{\"a}der, Patrick and Švara, Elena Motivans and Mozarowski, Steven and Rakosy, Demetra and R{\"o}mermann, Christine and Schmitt-Jansen, Mechthild and Stoof-Leichsenring, Kathleen R. and Stratmann, Frank and Treudler, Regina and Virtanen, Risto and Wendt-Potthoff, Katrin and Wilhelm, Christian}, title = {The potential of multispectral imaging flow cytometry for environmental monitoring}, series = {Cytometry part A}, volume = {101}, journal = {Cytometry part A}, number = {9}, publisher = {Wiley}, address = {Hoboken}, issn = {1552-4922}, doi = {10.1002/cyto.a.24658}, pages = {782 -- 799}, year = {2022}, abstract = {Environmental monitoring involves the quantification of microscopic cells and particles such as algae, plant cells, pollen, or fungal spores. Traditional methods using conventional microscopy require expert knowledge, are time-intensive and not well-suited for automated high throughput. Multispectral imaging flow cytometry (MIFC) allows measurement of up to 5000 particles per second from a fluid suspension and can simultaneously capture up to 12 images of every single particle for brightfield and different spectral ranges, with up to 60x magnification. The high throughput of MIFC has high potential for increasing the amount and accuracy of environmental monitoring, such as for plant-pollinator interactions, fossil samples, air, water or food quality that currently rely on manual microscopic methods. Automated recognition of particles and cells is also possible, when MIFC is combined with deep-learning computational techniques. Furthermore, various fluorescence dyes can be used to stain specific parts of the cell to highlight physiological and chemical features including: vitality of pollen or algae, allergen content of individual pollen, surface chemical composition (carbohydrate coating) of cells, DNA- or enzyme-activity staining. Here, we outline the great potential for MIFC in environmental research for a variety of research fields and focal organisms. In addition, we provide best practice recommendations.}, language = {en} } @article{VogelClausAhringetal.2022, author = {Vogel, Annemarie and Claus, Inga and Ahring, Sigrid and Gruber, Doreen and Haghikia, Aiden and Frank, Ulrike and Dziewas, Rainer and Ebersbach, Georg and Gandor, Florin and Warnecke, Tobias}, title = {Endoscopic characteristics of dysphagia in multiple system atrophy}, series = {Movement disorders : official journal of the Movement Disorder Society}, volume = {37}, journal = {Movement disorders : official journal of the Movement Disorder Society}, number = {3}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0885-3185}, doi = {10.1002/mds.28854}, pages = {535 -- 544}, year = {2022}, abstract = {Background Dysphagia is a major clinical concern in multiple system atrophy (MSA). A detailed evaluation of its major endoscopic features compared with Parkinson's disease (PD) is lacking. Objective This study systematically assessed dysphagia in MSA compared with PD and correlated subjective dysphagia to objective endoscopic findings. Methods Fifty-seven patients with MSA (median, 64 [interquartile range (IQR): 59-71] years; 35 women) underwent flexible endoscopic evaluation of swallowing using a specific MSA-flexible endoscopic evaluation of swallowing task protocol. Findings were compared with an age-matched cohort of 57 patients with PD (median, 67 [interquartile range: 60-73] years; 28 women). In a subcohort, subjective dysphagia was assessed using the Swallowing Disturbance Questionnaire and correlated to endoscopy findings. Results Patients with MSA predominantly showed symptoms suggestive of oral-phase disturbance (premature spillage, 75.4\%, piecemeal deglutition, 75.4\%). Pharyngeal-phase symptoms occurred less often (pharyngeal residues, 50.9\%; penetration/aspiration, 28.1\%). In contrast, pharyngeal symptoms were the most common finding in PD (pharyngeal residues, 47.4\%). Oral symptoms occurred less frequently in PD (premature spillage, 15.8\%, P < 0.001; piecemeal deglutition, 1.8\%, P < 0.01). Patients with MSA had a greater risk for oral-phase disturbances with increased disease severity (P < 0.05; odds ratio, 3.15). Patients with MSA showed a significantly higher intraindividual interswallow variability compared with PD. When correlating Swallowing Disturbance Questionnaire scores with endoscopy results, its cutoff, validated for PD, was not sensitive enough to identify patients with MSA with dysphagia. We developed a subscore for identifying dysphagia in MSA and calculated a new cutoff (sensitivity 85\%, specificity 100\%). Conclusions In contrast with patients with PD, patients with dysphagic MSA more frequently present with oral-phase symptoms and a significantly higher intraindividual interswallow variability. A novel Swallowing Disturbance Questionnaire MSA subscore may be a valuable tool to identify patients with MSA with early oropharyngeal dysphagia.}, language = {en} } @article{KetelhutBittmannScheffleretal.2003, author = {Ketelhut, Kerstin and Bittmann, Frank and Scheffler, Christiane and Morgenstern, Ulrike}, title = {Vergleichsuntersuchung {\"u}ber K{\"o}rpermaße und motorische F{\"a}higkeiten bei Kindern}, year = {2003}, language = {de} }